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3EA5
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BU of 3ea5 by Molmil
Kap95p Binding Induces the Switch Loops of RanGDP to adopt the GTP-bound Conformation: Implications for Nuclear Import Complex Assembly Dynamics
Descriptor: GTP-binding nuclear protein Ran, GUANOSINE-5'-DIPHOSPHATE, Importin subunit beta-1, ...
Authors:Forwood, J.K, Lonhienne, J.K, Guncar, G, Stewart, M, Marfori, M, Kobe, B.
Deposit date:2008-08-24
Release date:2008-10-21
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Kap95p binding induces the switch loops of RanGDP to adopt the GTP-bound conformation: implications for nuclear import complex assembly dynamics.
J.Mol.Biol., 383, 2008
2V1O
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BU of 2v1o by Molmil
Crystal structure of N-terminal domain of acyl-CoA thioesterase 7
Descriptor: COENZYME A, CYTOSOLIC ACYL COENZYME A THIOESTER HYDROLASE
Authors:Forwood, J.K, Thakur, A.S, Guncar, G, Marfori, M, Mouradov, D, Meng, W.N, Robinson, J, Huber, T, Kellie, S, Martin, J.L, Hume, D.A, Kobe, B.
Deposit date:2007-05-28
Release date:2007-06-26
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Structural Basis for Recruitment of Tandem Hotdog Domains in Acyl-Coa Thioesterase 7 and its Role in Inflammation.
Proc.Natl.Acad.Sci.USA, 104, 2007
3SPS
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BU of 3sps by Molmil
Crystal Structure of Apo-Hexameric Acyl-CoA Thioesterase
Descriptor: Acyl-CoA hydrolase
Authors:Forwood, J.K, Marfori, M, Kobe, B.
Deposit date:2011-07-03
Release date:2011-08-17
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Ligand-Induced Conformational Changes within a Hexameric Acyl-CoA Thioesterase
To be Published
6RPK
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BU of 6rpk by Molmil
non-expanded bat circovirus with DNA VLP
Descriptor: Capsid protein
Authors:Forwood, J.K, Luque, D, Mata, C.P, Das, S, Raidal, S.
Deposit date:2019-05-14
Release date:2020-11-25
Method:ELECTRON MICROSCOPY (2.84 Å)
Cite:non-expanded bat circovirus with DNA VLP
To Be Published
6RPO
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BU of 6rpo by Molmil
bat circovirus without DNA VLP
Descriptor: bat circovirus capsid protein
Authors:Forwood, J.K, Luque, D, Mata, C.P, Das, S, Raidal, S.
Deposit date:2019-05-14
Release date:2020-11-25
Method:ELECTRON MICROSCOPY (2.39 Å)
Cite:bat circovirus without DNA VLP
To Be Published
6RPL
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BU of 6rpl by Molmil
Expanded bat circovirus with DNA VLP
Descriptor: Capsid protein
Authors:Forwood, J.K, Luque, D, Mata, C.P, Das, S, Raidal, S.
Deposit date:2019-05-14
Release date:2020-11-25
Method:ELECTRON MICROSCOPY (3.85 Å)
Cite:expanded bat circovirus with DNA VLP
To Be Published
3ND2
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BU of 3nd2 by Molmil
Structure of Yeast Importin-beta (Kap95p)
Descriptor: Importin subunit beta-1
Authors:Forwood, J.K, Kobe, B.
Deposit date:2010-06-06
Release date:2010-07-07
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Quantitative Structural Analysis of Importin-beta Flexibility: Paradigm for Solenoid Protein Structures
Structure, 18, 2010
2Q2B
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BU of 2q2b by Molmil
Crystal structure of the C-terminal domain of mouse acyl-CoA thioesterase 7
Descriptor: Cytosolic acyl coenzyme A thioester hydrolase
Authors:Guncar, G, Forwood, J.K, Kobe, B.
Deposit date:2007-05-27
Release date:2007-07-17
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for recruitment of tandem hotdog domains in acyl-CoA thioesterase 7 and its role in inflammation.
Proc.Natl.Acad.Sci.Usa, 104, 2007
6UDS
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BU of 6uds by Molmil
Crystal structure of a putative 3-oxoacyl-ACP reductase (FabG) from Acinetobacter baumannii
Descriptor: 3-oxoacyl-(Acyl-carrier-protein) reductase
Authors:Forwood, J.K, Cross, E.M.
Deposit date:2019-09-19
Release date:2019-10-09
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Insights into Acinetobacter baumannii fatty acid synthesis 3-oxoacyl-ACP reductases.
Sci Rep, 11, 2021
7JVO
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BU of 7jvo by Molmil
Importin alpha bound to the C-terminus of ACE2
Descriptor: ARG-LYS-LYS-LYS-ASN-LYS-ALA, Importin subunit alpha-1
Authors:Forwood, J.K, Cross, E.M, Tsimbalyuk, S.
Deposit date:2020-08-22
Release date:2020-10-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Targeting novel LSD1-dependent ACE2 demethylation domains inhibits SARS-CoV-2 replication.
Cell Discov, 7, 2021
6WPR
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BU of 6wpr by Molmil
Crystal structure of a putative 3-oxoacyl-ACP reductase (FabG) with NADP(H) from Acinetobacter baumannii
Descriptor: 3-oxoacyl-[acyl-carrier-protein] reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Cross, E.M, Forwood, J.K.
Deposit date:2020-04-27
Release date:2020-06-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Insights into Acinetobacter baumannii fatty acid synthesis 3-oxoacyl-ACP reductases.
Sci Rep, 11, 2021
8G8Q
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BU of 8g8q by Molmil
RelB NLS in complex with Importin alpha 2
Descriptor: Importin subunit alpha-1, bacterial peptide, monopartite p52 NLS
Authors:Tsimbslyuk, S, Stewart, M, Forwood, J.K.
Deposit date:2023-02-19
Release date:2024-02-21
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:p52 monopartite NLS in complex with Importin alpha 2
To Be Published
8G8R
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BU of 8g8r by Molmil
RelB NLS in complex with Importin alpha 2
Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Importin subunit alpha-1, Transcription factor RelB
Authors:Tsimbslyuk, S, Stewart, M, Forwood, J.K.
Deposit date:2023-02-19
Release date:2024-02-21
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:monopartite p52 NLS in complex with Importin alpha 2
To Be Published
8G8S
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BU of 8g8s by Molmil
bipartite p52 NLS in complex with Importin alpha 2
Descriptor: Importin subunit alpha-1, Nuclear factor NF-kappa-B p100 subunit isoform X1
Authors:Tsimbslyuk, S, Stewart, M, Forwood, J.K.
Deposit date:2023-02-19
Release date:2024-02-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:p52 bipartite NLS in complex with Importin alpha 2
To Be Published
5KLT
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BU of 5klt by Molmil
Prototypical P4[M]cNLS
Descriptor: Importin subunit alpha-1, Prototypical P4[M]cNLS
Authors:Smith, K.M, Forwood, J.K.
Deposit date:2016-06-25
Release date:2016-07-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Contribution of the residue at position 4 within classical nuclear localization signals to modulating interaction with importins and nuclear targeting.
Biochim Biophys Acta Mol Cell Res, 1865, 2018
5KLR
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BU of 5klr by Molmil
Prototypical P4[R]cNLS
Descriptor: Importin subunit alpha-1, Prototypical P4[R]cNLS
Authors:Smith, K.M, Forwood, J.K.
Deposit date:2016-06-25
Release date:2016-07-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Contribution of the residue at position 4 within classical nuclear localization signals to modulating interaction with importins and nuclear targeting.
Biochim Biophys Acta Mol Cell Res, 1865, 2018
6WX7
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BU of 6wx7 by Molmil
SOX2 bound to Importin-alpha 2
Descriptor: Importin subunit alpha-1, Transcription factor SOX-2
Authors:Bikshapathi, J, Stewart, M, Forwood, J.K, Aragao, D, Roman, N.
Deposit date:2020-05-09
Release date:2020-10-28
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for nuclear import selectivity of pioneer transcription factor SOX2.
Nat Commun, 12, 2021
6WX8
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BU of 6wx8 by Molmil
SOX2 bound to Importin-alpha 3
Descriptor: Importin subunit alpha-3, SULFATE ION, Transcription factor SOX-2
Authors:Bikshapathi, J, Stewart, M, Forwood, J.K, Aragao, D, Roman, N.
Deposit date:2020-05-10
Release date:2020-10-28
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for nuclear import selectivity of pioneer transcription factor SOX2.
Nat Commun, 12, 2021
6WX9
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BU of 6wx9 by Molmil
SOX2 bound to Importin-alpha 5
Descriptor: Importin subunit alpha-5, Transcription factor SOX-2
Authors:Bikshapathi, J, Stewart, M, Forwood, J.K, Aragao, D, Roman, N.
Deposit date:2020-05-10
Release date:2020-10-28
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for nuclear import selectivity of pioneer transcription factor SOX2.
Nat Commun, 12, 2021
6BVV
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BU of 6bvv by Molmil
Nipah virus W protein C-terminus in complex with Importin alpha 3
Descriptor: Importin subunit alpha-3, Protein W
Authors:Smith, K.M, Tsimbalyuk, S, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K.
Deposit date:2017-12-13
Release date:2018-07-04
Last modified:2023-03-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses.
Nat Commun, 9, 2018
2QVT
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BU of 2qvt by Molmil
Structure of Melampsora lini avirulence protein, AvrL567-D
Descriptor: AvrL567-D
Authors:Guncar, G, Wang, C.I, Forwood, J.K, Teh, T, Catanzariti, A.M, Lawrence, G, Schirra, H.J, Anderson, P.A, Ellis, J.G, Dodds, P.N, Kobe, B.
Deposit date:2007-08-08
Release date:2007-10-30
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Crystal structures of flax rust avirulence proteins AvrL567-A and -D reveal details of the structural basis for flax disease resistance specificity.
Plant Cell, 19, 2007
6UUV
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BU of 6uuv by Molmil
Crystal structure of a high molecular weight 3-oxoacyl-ACP reductase (FabG) from Acinetobacter baumannii crystal form 1
Descriptor: 3-ketoacyl-ACP reductase
Authors:Cross, E.M, Forwood, J.K.
Deposit date:2019-11-01
Release date:2019-12-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Insights into Acinetobacter baumannii fatty acid synthesis 3-oxoacyl-ACP reductases.
Sci Rep, 11, 2021
6UUT
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BU of 6uut by Molmil
Crystal structure of a high molecular weight 3-oxoacyl-ACP reductase (FabG) from Acinetobacter baumannii crystal form 2
Descriptor: 3-ketoacyl-ACP reductase
Authors:Cross, E.M, Forwood, J.K.
Deposit date:2019-10-31
Release date:2019-12-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Insights into Acinetobacter baumannii fatty acid synthesis 3-oxoacyl-ACP reductases.
Sci Rep, 11, 2021
4XY5
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BU of 4xy5 by Molmil
Crystal Structure of mutant (Asp52Ala) Hypothetical Thioesterase Protein SP_1851 from Streptococcus pneumoniae TIGR4
Descriptor: Hypothetical Thioesterase Protein SP_1851
Authors:Khandokar, Y.B, Srivastava, P, Forwood, J.K.
Deposit date:2015-02-02
Release date:2015-05-06
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of mutant (Asp52Ala) Hypothetical Thioesterase Protein SP_1851 from Streptococcus pneumoniae TIGR4
To Be Published
4YLT
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BU of 4ylt by Molmil
Crystal structure of beta-ketoacyl-ACP synthase III (FabH) from Yersinia pestis
Descriptor: 3-oxoacyl-[acyl-carrier-protein] synthase 3
Authors:Nanson, J.D, Forwood, J.K.
Deposit date:2015-03-05
Release date:2015-04-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Characterisation of the Beta-Ketoacyl-Acyl Carrier Protein Synthases, FabF and FabH, of Yersinia pestis.
Sci Rep, 5, 2015

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