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7NJ5
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BU of 7nj5 by Molmil
1918 H1N1 Viral influenza polymerase heterotrimer with Nb8199 core
分子名称: Nb8199 Core, Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ...
著者Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M.
登録日2021-02-16
公開日2021-12-01
最終更新日2022-02-09
実験手法ELECTRON MICROSCOPY (4.63 Å)
主引用文献Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
7NIS
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BU of 7nis by Molmil
1918 H1N1 Viral influenza polymerase heterotrimer with Nb8192 core
分子名称: Nanobody8192 core, Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ...
著者Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M.
登録日2021-02-13
公開日2021-12-01
最終更新日2022-02-09
実験手法ELECTRON MICROSCOPY (5.96 Å)
主引用文献Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
7NK8
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BU of 7nk8 by Molmil
1918 H1N1 Viral influenza polymerase heterotrimer with Nb8205 core
分子名称: Nb8205, Polymerase acidic protein, Polymerase basic protein 2,Polymerase basic protein 2, ...
著者Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M.
登録日2021-02-17
公開日2021-12-01
最終更新日2022-02-09
実験手法ELECTRON MICROSCOPY (5.34 Å)
主引用文献Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
7NFR
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BU of 7nfr by Molmil
Fujian capmidlink domain in complex with Nb8194
分子名称: GLYCEROL, NB8194, Polymerase basic protein 2, ...
著者Keown, J.R, Grimes, J.M, Fodor, E.
登録日2021-02-07
公開日2021-12-01
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
7NHA
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BU of 7nha by Molmil
1918 H1N1 Viral influenza polymerase heterotrimer - Endonuclease and priming loop ordered (Class2a)
分子名称: Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, RNA (5'-R(P*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*CP*C)-3'), ...
著者Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M.
登録日2021-02-10
公開日2021-12-01
最終更新日2022-02-09
実験手法ELECTRON MICROSCOPY (2.91 Å)
主引用文献Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
7NHX
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BU of 7nhx by Molmil
1918 H1N1 Viral influenza polymerase heterotrimer - full transcriptase (Class1)
分子名称: Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, RNA (5'-R(P*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*CP*C)-3'), ...
著者Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M.
登録日2021-02-11
公開日2021-12-01
最終更新日2022-02-09
実験手法ELECTRON MICROSCOPY (3.23 Å)
主引用文献Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
7NKR
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BU of 7nkr by Molmil
1918 H1N1 Viral influenza polymerase heterotrimer with Nb8210
分子名称: Nb8210, Polymerase acidic protein, Polymerase basic protein 2,Polymerase basic protein 2, ...
著者Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M.
登録日2021-02-18
公開日2021-12-01
最終更新日2022-02-09
実験手法ELECTRON MICROSCOPY (5.6 Å)
主引用文献Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
7NK4
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BU of 7nk4 by Molmil
1918 H1N1 Viral influenza polymerase heterotrimer with Nb8203 core
分子名称: Nanobody 8203, Polymerase acidic protein, Polymerase basic protein 2,Polymerase basic protein 2, ...
著者Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M.
登録日2021-02-17
公開日2021-12-01
最終更新日2022-02-09
実験手法ELECTRON MICROSCOPY (5.32 Å)
主引用文献Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
7NJ3
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BU of 7nj3 by Molmil
1918 H1N1 Viral influenza polymerase heterotrimer with Nb8196 core
分子名称: Nanobody8196 core, Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ...
著者Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M.
登録日2021-02-15
公開日2021-12-01
最終更新日2022-02-09
実験手法ELECTRON MICROSCOPY (4.48 Å)
主引用文献Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
7NKI
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BU of 7nki by Molmil
1918 H1N1 Viral influenza polymerase heterotrimer with Nb8209 core
分子名称: Nb8209, Polymerase acidic protein, Polymerase basic protein 2,Polymerase basic protein 2, ...
著者Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M.
登録日2021-02-18
公開日2021-12-01
最終更新日2022-02-09
実験手法ELECTRON MICROSCOPY (4.67 Å)
主引用文献Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
7NIK
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BU of 7nik by Molmil
1918 H1N1 Viral influenza polymerase heterotrimer with Nb8189 core
分子名称: Nanobody8189 core, Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ...
著者Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M.
登録日2021-02-12
公開日2021-12-01
最終更新日2022-02-09
実験手法ELECTRON MICROSCOPY (6.2 Å)
主引用文献Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
7NJ4
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BU of 7nj4 by Molmil
1918 H1N1 Viral influenza polymerase heterotrimer with Nb8198 core
分子名称: Nb8198 Core, Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ...
著者Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M.
登録日2021-02-16
公開日2021-12-01
最終更新日2022-02-09
実験手法ELECTRON MICROSCOPY (5.84 Å)
主引用文献Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
7NK6
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BU of 7nk6 by Molmil
1918 H1N1 Viral influenza polymerase heterotrimer with Nb8204
分子名称: Nb8204, Polymerase acidic protein, Polymerase basic protein 2,Polymerase basic protein 2, ...
著者Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M.
登録日2021-02-17
公開日2021-12-01
最終更新日2022-02-09
実験手法ELECTRON MICROSCOPY (6.72 Å)
主引用文献Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
7NI0
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BU of 7ni0 by Molmil
1918 H1N1 Viral influenza polymerase heterotrimer - Replicase (class 3)
分子名称: Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, RNA (5'-R(P*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*CP*C)-3'), ...
著者Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M.
登録日2021-02-11
公開日2021-12-01
最終更新日2022-02-09
実験手法ELECTRON MICROSCOPY (3.32 Å)
主引用文献Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
7NKA
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BU of 7nka by Molmil
1918 H1N1 Viral influenza polymerase heterotrimer with Nb8206
分子名称: NB8206, Polymerase acidic protein, Polymerase basic protein 2,Polymerase basic protein 2, ...
著者Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M.
登録日2021-02-17
公開日2021-12-01
最終更新日2022-02-09
実験手法ELECTRON MICROSCOPY (4.07 Å)
主引用文献Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
7NK1
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BU of 7nk1 by Molmil
1918 Influenza virus polymerase heterotirmer in complex with vRNA promoters and Nb8201
分子名称: Nanobody8201, Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ...
著者Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M.
登録日2021-02-17
公開日2021-12-01
最終更新日2022-02-09
実験手法ELECTRON MICROSCOPY (4.22 Å)
主引用文献Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
7NFQ
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BU of 7nfq by Molmil
Fujian capmidlink domain in complex with Nb8193
分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, Nb8193, ...
著者Keown, J.R, Grimes, J.M, Fodor, E.
登録日2021-02-07
公開日2021-12-01
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
7NIR
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BU of 7nir by Molmil
1918 H1N1 Viral influenza polymerase heterotrimer with Nb8191 core
分子名称: Nanobody8191 core, Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ...
著者Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M.
登録日2021-02-13
公開日2021-12-01
最終更新日2022-02-09
実験手法ELECTRON MICROSCOPY (6.7 Å)
主引用文献Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
7NJ7
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BU of 7nj7 by Molmil
1918 H1N1 Viral influenza polymerase heterotrimer with Nb8200 core
分子名称: Nb8200 core, Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ...
著者Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M.
登録日2021-02-16
公開日2021-12-01
最終更新日2022-02-09
実験手法ELECTRON MICROSCOPY (4.82 Å)
主引用文献Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
7NT8
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BU of 7nt8 by Molmil
Influenza virus H3N2 nucleoprotein - R416A mutant
分子名称: Glutathione S-transferase class-mu 26 kDa isozyme,Nucleoprotein
著者Keown, J.R, Knight, M.L, Grimes, J.M, Fodor, E.
登録日2021-03-09
公開日2021-07-07
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Structure of an H3N2 influenza virus nucleoprotein.
Acta Crystallogr.,Sect.F, 77, 2021
3EBJ
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BU of 3ebj by Molmil
Crystal structure of an avian influenza virus protein
分子名称: MAGNESIUM ION, Polymerase acidic protein
著者Yuan, P, Bartlam, M, Lou, Z, Chen, S, Rao, Z, Liu, Y.
登録日2008-08-27
公開日2009-02-10
最終更新日2021-11-10
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of an avian influenza polymerase PA(N) reveals an endonuclease active site
Nature, 458, 2009
6QNW
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BU of 6qnw by Molmil
Influenza A Polymerase Heterotrimer Human H3N2 Northern Territory 1968
分子名称: Polymerase acidic protein, Polymerase basic protein 2, RNA-directed RNA polymerase catalytic subunit
著者Keown, J.R, Fan, H, Grimes, J.M.
登録日2019-02-12
公開日2019-09-04
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.31 Å)
主引用文献Structures of influenza A virus RNA polymerase offer insight into viral genome replication.
Nature, 573, 2019
6F5O
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BU of 6f5o by Molmil
A mechanism for the activation of the influenza virus transcriptase
分子名称: 3' promoter vRNA, 5' promoter vRNA, Polymerase acidic protein, ...
著者Serna Martin, I, Grimes, J.M.
登録日2017-12-02
公開日2018-06-27
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (9.8 Å)
主引用文献A Mechanism for the Activation of the Influenza Virus Transcriptase.
Mol. Cell, 70, 2018
6F5P
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BU of 6f5p by Molmil
A mechanism for the activation of the influenza virus transcriptase
分子名称: ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA, DNA-directed RNA polymerase subunit, MAGNESIUM ION, ...
著者Serna Martin, I, Grimes, J.M.
登録日2017-12-02
公開日2018-09-19
実験手法X-RAY DIFFRACTION (4.14 Å)
主引用文献A Mechanism for the Activation of the Influenza Virus Transcriptase.
Mol. Cell, 70, 2018
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