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7NKA
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BU of 7nka by Molmil
1918 H1N1 Viral influenza polymerase heterotrimer with Nb8206
Descriptor: NB8206, Polymerase acidic protein, Polymerase basic protein 2,Polymerase basic protein 2, ...
Authors:Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M.
Deposit date:2021-02-17
Release date:2021-12-01
Last modified:2022-02-09
Method:ELECTRON MICROSCOPY (4.07 Å)
Cite:Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
7NKR
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BU of 7nkr by Molmil
1918 H1N1 Viral influenza polymerase heterotrimer with Nb8210
Descriptor: Nb8210, Polymerase acidic protein, Polymerase basic protein 2,Polymerase basic protein 2, ...
Authors:Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M.
Deposit date:2021-02-18
Release date:2021-12-01
Last modified:2022-02-09
Method:ELECTRON MICROSCOPY (5.6 Å)
Cite:Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
7NHA
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BU of 7nha by Molmil
1918 H1N1 Viral influenza polymerase heterotrimer - Endonuclease and priming loop ordered (Class2a)
Descriptor: Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, RNA (5'-R(P*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*CP*C)-3'), ...
Authors:Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M.
Deposit date:2021-02-10
Release date:2021-12-01
Last modified:2022-02-09
Method:ELECTRON MICROSCOPY (2.91 Å)
Cite:Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
7NFQ
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BU of 7nfq by Molmil
Fujian capmidlink domain in complex with Nb8193
Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, Nb8193, ...
Authors:Keown, J.R, Grimes, J.M, Fodor, E.
Deposit date:2021-02-07
Release date:2021-12-01
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
7NIK
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BU of 7nik by Molmil
1918 H1N1 Viral influenza polymerase heterotrimer with Nb8189 core
Descriptor: Nanobody8189 core, Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ...
Authors:Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M.
Deposit date:2021-02-12
Release date:2021-12-01
Last modified:2022-02-09
Method:ELECTRON MICROSCOPY (6.2 Å)
Cite:Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
7NJ5
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BU of 7nj5 by Molmil
1918 H1N1 Viral influenza polymerase heterotrimer with Nb8199 core
Descriptor: Nb8199 Core, Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ...
Authors:Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M.
Deposit date:2021-02-16
Release date:2021-12-01
Last modified:2022-02-09
Method:ELECTRON MICROSCOPY (4.63 Å)
Cite:Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
7NI0
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BU of 7ni0 by Molmil
1918 H1N1 Viral influenza polymerase heterotrimer - Replicase (class 3)
Descriptor: Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, RNA (5'-R(P*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*CP*C)-3'), ...
Authors:Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M.
Deposit date:2021-02-11
Release date:2021-12-01
Last modified:2022-02-09
Method:ELECTRON MICROSCOPY (3.32 Å)
Cite:Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
7NKC
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BU of 7nkc by Molmil
1918 H1N1 Viral influenza polymerase heterotrimer with Nb8207
Descriptor: Nb8207, Polymerase acidic protein, Polymerase basic protein 2,Polymerase basic protein 2, ...
Authors:Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M.
Deposit date:2021-02-17
Release date:2021-12-01
Last modified:2022-02-09
Method:ELECTRON MICROSCOPY (4.46 Å)
Cite:Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
7NIR
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BU of 7nir by Molmil
1918 H1N1 Viral influenza polymerase heterotrimer with Nb8191 core
Descriptor: Nanobody8191 core, Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ...
Authors:Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M.
Deposit date:2021-02-13
Release date:2021-12-01
Last modified:2022-02-09
Method:ELECTRON MICROSCOPY (6.7 Å)
Cite:Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
7NFT
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BU of 7nft by Molmil
Fujian capbinding domain in complex with Nb8208
Descriptor: Nb8208, Polymerase basic protein 2, SULFATE ION
Authors:Keown, J.R, Grimes, J.M, Fodor, E.
Deposit date:2021-02-07
Release date:2021-12-01
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.14 Å)
Cite:Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
7NK2
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BU of 7nk2 by Molmil
1918 H1N1 Viral influenza polymerase heterotrimer with Nb8202 core
Descriptor: Nanobody8202, Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ...
Authors:Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M.
Deposit date:2021-02-17
Release date:2021-12-01
Last modified:2022-02-09
Method:ELECTRON MICROSCOPY (4.84 Å)
Cite:Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
7NHC
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BU of 7nhc by Molmil
1918 H1N1 Viral influenza polymerase heterotrimer - Endonuclease ordered (Class2b)
Descriptor: Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, RNA (5'-R(P*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*CP*C)-3'), ...
Authors:Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M.
Deposit date:2021-02-10
Release date:2021-12-01
Last modified:2022-02-09
Method:ELECTRON MICROSCOPY (2.87 Å)
Cite:Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
7NJ4
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BU of 7nj4 by Molmil
1918 H1N1 Viral influenza polymerase heterotrimer with Nb8198 core
Descriptor: Nb8198 Core, Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ...
Authors:Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M.
Deposit date:2021-02-16
Release date:2021-12-01
Last modified:2022-02-09
Method:ELECTRON MICROSCOPY (5.84 Å)
Cite:Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
7NIL
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BU of 7nil by Molmil
1918 H1N1 Viral influenza polymerase heterotrimer with Nb8190 core
Descriptor: Nanobody8190 core, Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ...
Authors:Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M.
Deposit date:2021-02-12
Release date:2021-12-01
Last modified:2022-02-09
Method:ELECTRON MICROSCOPY (5.01 Å)
Cite:Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
7NK4
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BU of 7nk4 by Molmil
1918 H1N1 Viral influenza polymerase heterotrimer with Nb8203 core
Descriptor: Nanobody 8203, Polymerase acidic protein, Polymerase basic protein 2,Polymerase basic protein 2, ...
Authors:Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M.
Deposit date:2021-02-17
Release date:2021-12-01
Last modified:2022-02-09
Method:ELECTRON MICROSCOPY (5.32 Å)
Cite:Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
7NJ3
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BU of 7nj3 by Molmil
1918 H1N1 Viral influenza polymerase heterotrimer with Nb8196 core
Descriptor: Nanobody8196 core, Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ...
Authors:Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M.
Deposit date:2021-02-15
Release date:2021-12-01
Last modified:2022-02-09
Method:ELECTRON MICROSCOPY (4.48 Å)
Cite:Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
7NK8
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BU of 7nk8 by Molmil
1918 H1N1 Viral influenza polymerase heterotrimer with Nb8205 core
Descriptor: Nb8205, Polymerase acidic protein, Polymerase basic protein 2,Polymerase basic protein 2, ...
Authors:Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M.
Deposit date:2021-02-17
Release date:2021-12-01
Last modified:2022-02-09
Method:ELECTRON MICROSCOPY (5.34 Å)
Cite:Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
7NT8
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BU of 7nt8 by Molmil
Influenza virus H3N2 nucleoprotein - R416A mutant
Descriptor: Glutathione S-transferase class-mu 26 kDa isozyme,Nucleoprotein
Authors:Keown, J.R, Knight, M.L, Grimes, J.M, Fodor, E.
Deposit date:2021-03-09
Release date:2021-07-07
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Structure of an H3N2 influenza virus nucleoprotein.
Acta Crystallogr.,Sect.F, 77, 2021
3EBJ
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BU of 3ebj by Molmil
Crystal structure of an avian influenza virus protein
Descriptor: MAGNESIUM ION, Polymerase acidic protein
Authors:Yuan, P, Bartlam, M, Lou, Z, Chen, S, Rao, Z, Liu, Y.
Deposit date:2008-08-27
Release date:2009-02-10
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of an avian influenza polymerase PA(N) reveals an endonuclease active site
Nature, 458, 2009
6F5O
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BU of 6f5o by Molmil
A mechanism for the activation of the influenza virus transcriptase
Descriptor: 3' promoter vRNA, 5' promoter vRNA, Polymerase acidic protein, ...
Authors:Serna Martin, I, Grimes, J.M.
Deposit date:2017-12-02
Release date:2018-06-27
Last modified:2018-07-04
Method:ELECTRON MICROSCOPY (9.8 Å)
Cite:A Mechanism for the Activation of the Influenza Virus Transcriptase.
Mol. Cell, 70, 2018
6F5P
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BU of 6f5p by Molmil
A mechanism for the activation of the influenza virus transcriptase
Descriptor: ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA, DNA-directed RNA polymerase subunit, MAGNESIUM ION, ...
Authors:Serna Martin, I, Grimes, J.M.
Deposit date:2017-12-02
Release date:2018-09-19
Method:X-RAY DIFFRACTION (4.14 Å)
Cite:A Mechanism for the Activation of the Influenza Virus Transcriptase.
Mol. Cell, 70, 2018
6QNW
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BU of 6qnw by Molmil
Influenza A Polymerase Heterotrimer Human H3N2 Northern Territory 1968
Descriptor: Polymerase acidic protein, Polymerase basic protein 2, RNA-directed RNA polymerase catalytic subunit
Authors:Keown, J.R, Fan, H, Grimes, J.M.
Deposit date:2019-02-12
Release date:2019-09-04
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.31 Å)
Cite:Structures of influenza A virus RNA polymerase offer insight into viral genome replication.
Nature, 573, 2019
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