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7UY6
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BU of 7uy6 by Molmil
Tetrahymena telomerase at 2.9 Angstrom resolution
Descriptor: Telomerase La-related protein p65, Telomerase RNA, Telomerase associated protein p50, ...
Authors:He, Y, Song, H, Chan, H, Wang, Y, Liu, B, Susac, L, Zhou, Z.H, Feigon, J.
Deposit date:2022-05-06
Release date:2022-07-13
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structure of Tetrahymena telomerase-bound CST with polymerase alpha-primase.
Nature, 608, 2022
7UY5
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BU of 7uy5 by Molmil
Tetrahymena telomerase with CST
Descriptor: Telomerase La-related protein p65, Telomerase RNA, Telomerase associated protein p50, ...
Authors:He, Y, Song, H, Chan, H, Wang, Y, Liu, B, Susac, L, Zhou, Z.H, Feigon, J.
Deposit date:2022-05-06
Release date:2022-07-13
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of Tetrahymena telomerase-bound CST with polymerase alpha-primase.
Nature, 608, 2022
7UY8
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BU of 7uy8 by Molmil
Tetrahymena Polymerase alpha-Primase
Descriptor: DNA polymerase, DNA polymerase alpha subunit B, DNA primase, ...
Authors:He, Y, Song, H, Chan, H, Wang, Y, Liu, B, Susac, L, Zhou, Z.H, Feigon, J.
Deposit date:2022-05-06
Release date:2022-07-13
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structure of Tetrahymena telomerase-bound CST with polymerase alpha-primase.
Nature, 608, 2022
156D
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BU of 156d by Molmil
REFINED SOLUTION STRUCTURE OF THE DIMERIC QUADRUPLEX FORMED FROM THE OXYTRICHA TELOMERIC OLIGONUCLEOTIDE D(GGGGTTTTGGGG)
Descriptor: DNA (5'-D(*GP*GP*GP*GP*TP*TP*TP*TP*GP*GP*GP*G)-3')
Authors:Schultze, P, Smith, F.W, Feigon, J.
Deposit date:1994-01-17
Release date:1994-04-30
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Refined solution structure of the dimeric quadruplex formed from the Oxytricha telomeric oligonucleotide d(GGGGTTTTGGGG).
Structure, 2, 1994
4EYT
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BU of 4eyt by Molmil
Crystal structure of the C-terminal domain of Tetrahymena telomerase protein p65
Descriptor: SULFATE ION, Telomerase associated protein p65
Authors:Singh, M, Wang, Z, Koo, B.-K, Patel, A, Cascio, D, Collins, K, Feigon, J.
Deposit date:2012-05-01
Release date:2012-06-20
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Basis for Telomerase RNA Recognition and RNP Assembly by the Holoenzyme La Family Protein p65.
Mol.Cell, 47, 2012
6D6V
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BU of 6d6v by Molmil
CryoEM structure of Tetrahymena telomerase with telomeric DNA at 4.8 Angstrom resolution
Descriptor: DNA (5'-D(P*GP*TP*TP*GP*GP*GP*GP*TP*TP*GP*GP*GP*GP*TP*TP*GP*GP*GP*G)-3'), RNA (159-MER), Telomerase associated protein p65, ...
Authors:Jiang, J, Wang, Y, Susac, L, Chan, H, Basu, R, Zhou, Z.H, Feigon, J.
Deposit date:2018-04-22
Release date:2018-05-30
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Structure of Telomerase with Telomeric DNA.
Cell, 173, 2018
4PBD
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BU of 4pbd by Molmil
Crystal structure of the N-terminal CS domain of human Shq1
Descriptor: Protein SHQ1 homolog
Authors:Singh, M, Wang, Z, Cascio, D, Feigon, J.
Deposit date:2014-04-12
Release date:2015-01-14
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Structure and Interactions of the CS Domain of Human H/ACA RNP Assembly Protein Shq1.
J.Mol.Biol., 427, 2015
4PCK
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BU of 4pck by Molmil
Crystal structure of the P22S mutant of N-terminal CS domain of human Shq1
Descriptor: GLYCEROL, Protein SHQ1 homolog
Authors:Singh, M, Wang, Z, Cascio, D, Feigon, J.
Deposit date:2014-04-15
Release date:2015-01-14
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.401 Å)
Cite:Structure and Interactions of the CS Domain of Human H/ACA RNP Assembly Protein Shq1.
J.Mol.Biol., 427, 2015
4ERD
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BU of 4erd by Molmil
Crystal structure of the C-terminal domain of Tetrahymena telomerase protein p65 in complex with stem IV of telomerase RNA
Descriptor: 5'-R(P*GP*GP*UP*CP*GP*AP*CP*AP*UP*CP*UP*UP*CP*GP*GP*AP*UP*GP*GP*AP*CP*C)-3', POTASSIUM ION, Telomerase associated protein p65
Authors:Singh, M, Wang, Z, Koo, B.-K, Patel, A, Cascio, D, Collins, K, Feigon, J.
Deposit date:2012-04-19
Release date:2012-06-20
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.589 Å)
Cite:Structural Basis for Telomerase RNA Recognition and RNP Assembly by the Holoenzyme La Family Protein p65.
Mol.Cell, 47, 2012
5KQE
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BU of 5kqe by Molmil
Solution structure of P2a-J2a/b-P2b of medaka telomerase RNA
Descriptor: Telomerase RNA P2ab
Authors:Wang, Y, Feigon, J.
Deposit date:2016-07-06
Release date:2016-08-24
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural conservation in the template/pseudoknot domain of vertebrate telomerase RNA from teleost fish to human.
Proc.Natl.Acad.Sci.USA, 113, 2016
5KNW
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BU of 5knw by Molmil
Solution NMR structure of human LARP7 xRRM2
Descriptor: La-related protein 7
Authors:Eichhorn, C.D, Feigon, J.
Deposit date:2016-06-28
Release date:2016-10-12
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:hLARP7 C-terminal domain contains an xRRM that binds the 3' hairpin of 7SK RNA.
Nucleic Acids Res., 44, 2016
185D
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BU of 185d by Molmil
SEQUENCE SPECIFICITY OF QUINOXALINE ANTIBIOTICS. 1. SOLUTION STRUCTURE OF A 1:1 COMPLEX BETWEEN TRIOSTIN A AND [D(GACGTC)]2 AND COMPARISON WITH THE SOLUTION STRUCTURE OF THE [N-MECYS3, N-MECYS7]TANDEM-[D(GATATC)]2 COMPLEX
Descriptor: 2-CARBOXYQUINOXALINE, DNA (5'-D(*GP*AP*CP*GP*TP*C)-3'), TRIOSTIN A
Authors:Addess, K.J, Feigon, J.
Deposit date:1994-08-10
Release date:1995-02-07
Last modified:2017-11-01
Method:SOLUTION NMR
Cite:Sequence Specificity of Quinoxaline Antibiotics. 1. Solution Structure of a 1:1 Complex between Triostin a and [D(Gacgtc)]2 and Comparison with the Solution Structure of the [N-Mecys3,N-Mecys7]Tandem-[D(Gatatc)]2 Complex.
Biochemistry, 33, 1994
148D
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BU of 148d by Molmil
THREE-DIMENSIONAL SOLUTION STRUCTURE OF THE THROMBIN BINDING DNA APTAMER D(GGTTGGTGTGGTTGG)
Descriptor: DNA (5'-D(*GP*GP*TP*TP*GP*GP*TP*GP*TP*GP*GP*TP*TP*GP*G)-3')
Authors:Schultze, P, Macaya, R.F, Feigon, J.
Deposit date:1993-11-15
Release date:1994-04-30
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Three-dimensional solution structure of the thrombin-binding DNA aptamer d(GGTTGGTGTGGTTGG).
J.Mol.Biol., 235, 1994
6D12
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BU of 6d12 by Molmil
Crystal structure of C-terminal xRRM domain of human Larp7 bound to 7SK stem-loop 4 RNA
Descriptor: La-related protein 7, human 7SK RNA stem-loop 4
Authors:Eichhorn, C.D, Cascio, D, Sawaya, M.R, Feigon, J.
Deposit date:2018-04-11
Release date:2018-06-27
Last modified:2020-01-15
Method:X-RAY DIFFRACTION (2.205 Å)
Cite:Structural basis for recognition of human 7SK long noncoding RNA by the La-related protein Larp7.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6DCB
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BU of 6dcb by Molmil
Structure of methylphosphate capping enzyme methyltransferase domain in complex with 5' end of 7SK RNA
Descriptor: 7SK snRNA methylphosphate capping enzyme, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, ...
Authors:Yang, Y, Eichhorn, C, Cascio, D, Feigon, J.
Deposit date:2018-05-04
Release date:2018-12-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.998 Å)
Cite:Structural basis of 7SK RNA 5'-gamma-phosphate methylation and retention by MePCE.
Nat. Chem. Biol., 15, 2019
6DCC
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BU of 6dcc by Molmil
Structure of methylphosphate capping enzyme methyltransferase domain in complex with 5' end of 7SK RNA
Descriptor: 7SK snRNA methylphosphate capping enzyme, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, ...
Authors:Yang, Y, Eichhorn, C, Cascio, D, Feigon, J.
Deposit date:2018-05-04
Release date:2018-12-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis of 7SK RNA 5'-gamma-phosphate methylation and retention by MePCE.
Nat. Chem. Biol., 15, 2019
1Y2Y
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BU of 1y2y by Molmil
Structural Characterization of Nop10p using Nuclear Magnetic Resonance Spectroscopy
Descriptor: Ribosome biogenesis protein Nop10
Authors:Khanna, M, Wu, H, Johansson, C, Caizergues-Ferrer, M, Feigon, J.
Deposit date:2004-11-23
Release date:2005-12-06
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Structural study of the H/ACA snoRNP components Nop10p and the 3' hairpin of U65 snoRNA
RNA, 12, 2006
1CG7
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BU of 1cg7 by Molmil
HMG PROTEIN NHP6A FROM SACCHAROMYCES CEREVISIAE
Descriptor: PROTEIN (NON HISTONE PROTEIN 6 A)
Authors:Allain, F.H.T, Yen, Y.M, Masse, J.E, Schultze, P, Dieckmann, T, Johnson, R.C, Feigon, J.
Deposit date:1999-03-27
Release date:1999-10-14
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution structure of the HMG protein NHP6A and its interaction with DNA reveals the structural determinants for non-sequence-specific binding.
EMBO J., 18, 1999
2P89
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BU of 2p89 by Molmil
Solution structure of the 3' pseudouridyation pocket of U65 snoRNA with bound substrate
Descriptor: 28S rRNA, U65 H/ACA snoRNA
Authors:Wu, H, Feigon, J.
Deposit date:2007-03-22
Release date:2007-04-03
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:H/ACA small nucleolar RNA pseudouridylation pockets bind substrate RNA to form three-way junctions that position the target U for modification.
Proc.Natl.Acad.Sci.Usa, 104, 2007
1FJE
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BU of 1fje by Molmil
SOLUTION STRUCTURE OF NUCLEOLIN RBD12 IN COMPLEX WITH SNRE RNA
Descriptor: NUCLEOLIN RBD12, SNRE RNA
Authors:Allain, F.H.T, Bouvet, P, Dieckmann, T, Feigon, J.
Deposit date:2000-08-08
Release date:2001-01-03
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Molecular basis of sequence-specific recognition of pre-ribosomal RNA by nucleolin.
EMBO J., 19, 2000
1P98
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BU of 1p98 by Molmil
High-resolution NMR structure of the Ubl-domain of HHR23A
Descriptor: UV excision repair protein RAD23 homolog A
Authors:Mueller, T.D, Feigon, J.
Deposit date:2003-05-09
Release date:2003-10-07
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Structural determinants for the binding of ubiquitin-like domains to the proteasome.
Embo J., 22, 2003
1IE1
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BU of 1ie1 by Molmil
NMR Solution Structure of an In Vitro Selected RNA which is Sequence Specifically Recognized by Hamster Nucleolin RBD12.
Descriptor: 5'-R(*GP*GP*CP*CP*GP*AP*AP*AP*UP*CP*CP*CP*GP*AP*AP*GP*UP*AP*GP*GP*CP*C)-3'
Authors:Bouvet, P, Allain, F.H.-T, Finger, L.D, Dieckmann, T, Feigon, J.
Deposit date:2001-04-05
Release date:2001-06-20
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Recognition of pre-formed and flexible elements of an RNA stem-loop by nucleolin.
J.Mol.Biol., 309, 2001
1IFY
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BU of 1ify by Molmil
Solution Structure of the Internal UBA Domain of HHR23A
Descriptor: UV EXCISION REPAIR PROTEIN RAD23 HOMOLOG A
Authors:Mueller, T.D, Feigon, J.
Deposit date:2001-04-13
Release date:2002-07-03
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution structures of UBA domains reveal a conserved hydrophobic surface for protein-protein interactions.
J.Mol.Biol., 319, 2002
1AFX
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BU of 1afx by Molmil
UGAA EUKARYOTIC RIBOSOMAL RNA TETRALOOP, NMR, 13 STRUCTURES
Descriptor: RNA (5'-R(*GP*GP*UP*GP*UP*GP*AP*AP*CP*AP*CP*C)-3')
Authors:Butcher, S.E, Dieckmann, T, Feigon, J.
Deposit date:1997-03-15
Release date:1997-05-15
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Solution structure of the loop B domain from the hairpin ribozyme.
Nat.Struct.Biol., 6, 1999
1B36
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BU of 1b36 by Molmil
SOLUTION STRUCTURE OF THE HAIRPIN RIBOZYME LOOP B DOMAIN RNA, NMR, 10 STRUCTURES
Descriptor: RNA (RNA LOOP B)
Authors:Butcher, S.E, Dieckmann, T, Feigon, J.
Deposit date:1998-12-17
Release date:1998-12-23
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution structure of the loop B domain from the hairpin ribozyme.
Nat.Struct.Biol., 6, 1999

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