2EUY
 
 | | Solution structure of the internal loop of human U65 H/ACA snoRNA 3' hairpin | | 分子名称: | U65 box H/ACA snoRNA | | 著者 | Feigon, J, Khanna, M, Wu, H, Johansson, C, Caizergues-Ferrer, M. | | 登録日 | 2005-10-30 | | 公開日 | 2006-01-03 | | 最終更新日 | 2022-03-09 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural study of the H/ACA snoRNP components Nop10p and the 3' hairpin of U65 snoRNA.
Rna, 12, 2006
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2QH3
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2QH2
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2QH4
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5DFM
 | | Structure of Tetrahymena telomerase p19 fused to MBP | | 分子名称: | GLYCEROL, Maltose-binding periplasmic protein,Telomerase-associated protein 19, SULFATE ION, ... | | 著者 | Chan, H, Cascio, D, Sawaya, M.R, Feigon, J. | | 登録日 | 2015-08-27 | | 公開日 | 2015-10-28 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.301 Å) | | 主引用文献 | Structure of Tetrahymena telomerase reveals previously unknown subunits, functions, and interactions.
Science, 350, 2015
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1LWM
 | | Solution Structure of the Sequence-Non-Specific HMGB protein NHP6A | | 分子名称: | NONHISTONE CHROMOSOMAL PROTEIN 6A | | 著者 | Masse, J.E, Wong, B, Yen, Y.-M, Allain, F.H.-T, Johnson, R.C, Feigon, J. | | 登録日 | 2002-05-31 | | 公開日 | 2002-10-16 | | 最終更新日 | 2022-02-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The S. cerevisiae architectural HMGB protein NHP6A complexed with DNA: DNA and protein conformational changes upon binding
J.Mol.Biol., 323, 2002
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4EYT
 | | Crystal structure of the C-terminal domain of Tetrahymena telomerase protein p65 | | 分子名称: | SULFATE ION, Telomerase associated protein p65 | | 著者 | Singh, M, Wang, Z, Koo, B.-K, Patel, A, Cascio, D, Collins, K, Feigon, J. | | 登録日 | 2012-05-01 | | 公開日 | 2012-06-20 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural Basis for Telomerase RNA Recognition and RNP Assembly by the Holoenzyme La Family Protein p65.
Mol.Cell, 47, 2012
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6TZN
 | | Structure of S. pombe telomerase accessory protein Pof8 C-terminal domain | | 分子名称: | NITRATE ION, Protein pof8 | | 著者 | Basu, R.S, Cascio, D, Eichhorn, C.D, Feigon, J. | | 登録日 | 2019-08-12 | | 公開日 | 2020-08-19 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Structure of S. pombe telomerase protein Pof8 C-terminal domain is an xRRM conserved among LARP7 proteins.
Rna Biol., 18, 2021
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6D6V
 | | CryoEM structure of Tetrahymena telomerase with telomeric DNA at 4.8 Angstrom resolution | | 分子名称: | DNA (5'-D(P*GP*TP*TP*GP*GP*GP*GP*TP*TP*GP*GP*GP*GP*TP*TP*GP*GP*GP*G)-3'), RNA (159-MER), Telomerase associated protein p65, ... | | 著者 | Jiang, J, Wang, Y, Susac, L, Chan, H, Basu, R, Zhou, Z.H, Feigon, J. | | 登録日 | 2018-04-22 | | 公開日 | 2018-05-30 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | | 主引用文献 | Structure of Telomerase with Telomeric DNA.
Cell, 173, 2018
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8GAP
 | | Structure of LARP7 protein p65-telomerase RNA complex in telomerase | | 分子名称: | Telomerase La-related protein p65, Telomerase RNA, Telomerase associated protein p50, ... | | 著者 | Wang, Y, He, Y, Wang, Y, Yang, Y, Singh, M, Eichhorn, C.D, Zhou, Z.H, Feigon, J. | | 登録日 | 2023-02-23 | | 公開日 | 2023-06-28 | | 最終更新日 | 2023-07-19 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structure of LARP7 Protein p65-telomerase RNA Complex in Telomerase Revealed by Cryo-EM and NMR.
J.Mol.Biol., 435, 2023
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2DA8
 | | SOLUTION STRUCTURE OF A COMPLEX BETWEEN (N-MECYS3,N-MECYS7)TANDEM AND (D(GATATC))2 | | 分子名称: | 2-CARBOXYQUINOXALINE, DNA (5'-D(*GP*AP*TP*AP*TP*C)-3'), TRIOSTIN A | | 著者 | Addess, K.J, Sinsheimer, J.S, Feigon, J. | | 登録日 | 1993-04-09 | | 公開日 | 1994-01-31 | | 最終更新日 | 2017-11-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution Structure of a Complex between [N-Mecys3,N-Mecys7]Tandem and [D(Gatatc)]2.
Biochemistry, 32, 1993
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1YMO
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6DCB
 | | Structure of methylphosphate capping enzyme methyltransferase domain in complex with 5' end of 7SK RNA | | 分子名称: | 7SK snRNA methylphosphate capping enzyme, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, ... | | 著者 | Yang, Y, Eichhorn, C, Cascio, D, Feigon, J. | | 登録日 | 2018-05-04 | | 公開日 | 2018-12-19 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.998 Å) | | 主引用文献 | Structural basis of 7SK RNA 5'-gamma-phosphate methylation and retention by MePCE.
Nat. Chem. Biol., 15, 2019
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230D
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5DFN
 | | Structure of Tetrahymena Telomerase P45 C-terminal domain | | 分子名称: | Telomerase associated protein p45 | | 著者 | Chan, H, Cascio, D, Sawaya, M.R, Feigon, J. | | 登録日 | 2015-08-27 | | 公開日 | 2015-10-28 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.382 Å) | | 主引用文献 | Structure of Tetrahymena telomerase reveals previously unknown subunits, functions, and interactions.
Science, 350, 2015
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156D
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1WAN
 | | DNA DTA TRIPLEX, NMR, 7 STRUCTURES | | 分子名称: | DNA (5'-D(*AP*GP*AP*TP*AP*GP*AP*AP*CP*CP*CP*CP*TP*TP*CP*TP*AP*TP*CP*TP*TP*AP*TP*AP*TP*CP*TP*(D3)P*TP*CP*TP*T)-3') | | 著者 | Wang, E, Koshlap, K.M, Gillespie, P, Dervan, P.B, Feigon, J. | | 登録日 | 1996-01-14 | | 公開日 | 1996-07-11 | | 最終更新日 | 2022-03-02 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of a pyrimidine-purine-pyrimidine triplex containing the sequence-specific intercalating non-natural base D3.
J.Mol.Biol., 257, 1996
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2K96
 | | Solution structure of the RDC-refined P2B-P3 pseudoknot from human telomerase RNA (delta U177) | | 分子名称: | TELOMERASE RNA P2B-P3 PSEUDOKNOT | | 著者 | Kim, N.-K, Zhang, Q, Zhou, J, Theimer, C.A, Peterson, R.D, Feigon, J. | | 登録日 | 2008-09-29 | | 公開日 | 2008-11-25 | | 最終更新日 | 2022-03-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution Structure and Dynamics of the Wild-type Pseudoknot of Human Telomerase RNA.
J.Mol.Biol., 384, 2008
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6DCC
 | | Structure of methylphosphate capping enzyme methyltransferase domain in complex with 5' end of 7SK RNA | | 分子名称: | 7SK snRNA methylphosphate capping enzyme, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, ... | | 著者 | Yang, Y, Eichhorn, C, Cascio, D, Feigon, J. | | 登録日 | 2018-05-04 | | 公開日 | 2018-12-19 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural basis of 7SK RNA 5'-gamma-phosphate methylation and retention by MePCE.
Nat. Chem. Biol., 15, 2019
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3EUD
 | | Structure of the CS domain of the essential H/ACA RNP assembly protein Shq1p | | 分子名称: | Protein SHQ1 | | 著者 | Singh, M, Cascio, D, Gonzales, F.A, Heckmann, N, Chanfreau, G, Feigon, J. | | 登録日 | 2008-10-09 | | 公開日 | 2008-11-18 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structure and Functional Studies of the CS Domain of the Essential H/ACA Ribonucleoparticle Assembly Protein SHQ1.
J.Biol.Chem., 284, 2009
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4ERD
 | | Crystal structure of the C-terminal domain of Tetrahymena telomerase protein p65 in complex with stem IV of telomerase RNA | | 分子名称: | 5'-R(P*GP*GP*UP*CP*GP*AP*CP*AP*UP*CP*UP*UP*CP*GP*GP*AP*UP*GP*GP*AP*CP*C)-3', POTASSIUM ION, Telomerase associated protein p65 | | 著者 | Singh, M, Wang, Z, Koo, B.-K, Patel, A, Cascio, D, Collins, K, Feigon, J. | | 登録日 | 2012-04-19 | | 公開日 | 2012-06-20 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.589 Å) | | 主引用文献 | Structural Basis for Telomerase RNA Recognition and RNP Assembly by the Holoenzyme La Family Protein p65.
Mol.Cell, 47, 2012
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185D
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148D
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7SLQ
 | | Cryo-EM structure of 7SK core RNP with circular RNA | | 分子名称: | 7SK snRNA methylphosphate capping enzyme, La-related protein 7, Minimal circular 7SK RNA, ... | | 著者 | Yang, Y, Liu, S, Zhou, Z.H, Feigon, J. | | 登録日 | 2021-10-24 | | 公開日 | 2022-03-30 | | 最終更新日 | 2022-05-18 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Structural basis of RNA conformational switching in the transcriptional regulator 7SK RNP.
Mol.Cell, 82, 2022
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7SLP
 | | Cryo-EM structure of 7SK core RNP with linear RNA | | 分子名称: | 7SK snRNA methylphosphate capping enzyme, La-related protein 7, Linear 7SK RNA, ... | | 著者 | Yang, Y, Liu, S, Zhou, Z.H, Feigon, J. | | 登録日 | 2021-10-24 | | 公開日 | 2022-03-30 | | 最終更新日 | 2022-05-18 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Structural basis of RNA conformational switching in the transcriptional regulator 7SK RNP.
Mol.Cell, 82, 2022
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