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6QPI
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BU of 6qpi by Molmil
Cryo-EM structure of calcium-free mTMEM16F lipid scramblase in nanodisc
Descriptor: Anoctamin-6
Authors:Alvadia, C, Lim, N.K, Clerico Mosina, V, Oostergetel, G.T, Dutzler, R, Paulino, C.
Deposit date:2019-02-14
Release date:2019-03-06
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cryo-EM structures and functional characterization of the murine lipid scramblase TMEM16F.
Elife, 8, 2019
6QM5
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BU of 6qm5 by Molmil
Cryo-EM structure of calcium-bound nhTMEM16 lipid scramblase in DDM
Descriptor: CALCIUM ION, Predicted protein
Authors:Kalienkova, V, Clerico Mosina, V, Bryner, L, Oostergetel, G.T, Dutzler, R, Paulino, C.
Deposit date:2019-02-01
Release date:2019-03-06
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Stepwise activation mechanism of the scramblase nhTMEM16 revealed by cryo-EM.
Elife, 8, 2019
2EXW
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BU of 2exw by Molmil
Crystal structure of a EcClC-Fab complex in the absence of bound ions
Descriptor: Fab Fragment (Heavy Chain), Fab Fragment (Light Chain), H(+)/Cl(-) exchange transporter clcA
Authors:Lobet, S, Dutzler, R.
Deposit date:2005-11-09
Release date:2006-01-24
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Ion-binding properties of the ClC chloride selectivity filter.
Embo J., 25, 2006
2EXY
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BU of 2exy by Molmil
Crystal structure of the E148Q Mutant of EcClC, Fab complexed in absence of bound ions
Descriptor: Fab Fragment (Heavy Chain), Fab Fragment (Light Chain), H(+)/Cl(-) exchange transporter clcA
Authors:Lobet, S, Dutzler, R.
Deposit date:2005-11-09
Release date:2006-01-24
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Ion-binding properties of the ClC chloride selectivity filter.
Embo J., 25, 2006
2EZ0
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BU of 2ez0 by Molmil
Crystal structure of the S107A/E148Q/Y445A mutant of EcClC, in complex with a FaB fragment
Descriptor: BROMIDE ION, Fab Fragment (Heavy Chain), Fab Fragment (Light Chain), ...
Authors:Lobet, S, Dutzler, R.
Deposit date:2005-11-10
Release date:2006-01-24
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3.54 Å)
Cite:Ion-binding properties of the ClC chloride selectivity filter.
Embo J., 25, 2006
2HT2
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BU of 2ht2 by Molmil
Structure of the Escherichia coli ClC chloride channel Y445H mutant and Fab complex
Descriptor: BROMIDE ION, Fab fragment, heavy chain, ...
Authors:Accardi, A, Lobet, S, Williams, C, Miller, C, Dutzler, R.
Deposit date:2006-07-25
Release date:2006-09-19
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (3.32 Å)
Cite:Synergism Between Halide Binding and Proton Transport in a CLC-type Exchanger.
J.Mol.Biol., 362, 2006
2HLF
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BU of 2hlf by Molmil
Structure of the Escherichis coli ClC chloride channel Y445E mutant and Fab complex
Descriptor: BROMIDE ION, Fab Fragment, Heavy chain, ...
Authors:Accardi, A, Lobet, S, Williams, C, Miller, C, Dutzler, R.
Deposit date:2006-07-07
Release date:2006-09-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Synergism Between Halide Binding and Proton Transport in a CLC-type Exchanger
J.Mol.Biol., 362, 2006
2HT3
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BU of 2ht3 by Molmil
Structure of the Escherichia coli ClC chloride channel Y445L mutant and Fab complex
Descriptor: BROMIDE ION, Fab fragment, Heavy chain, ...
Authors:Accardi, A, Lobet, S, Williams, C, Miller, C, Dutzler, R.
Deposit date:2006-07-25
Release date:2006-09-19
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Synergism between halide binding and proton transport in a CLC-type exchanger
J.Mol.Biol., 362, 2006
2HT4
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BU of 2ht4 by Molmil
Structure of the Escherichia coli ClC chloride channel Y445W mutant and Fab complex
Descriptor: BROMIDE ION, Fab fragment, Heavy chain, ...
Authors:Accardi, A, Lobet, S, Williams, C, Miller, C, Dutzler, R.
Deposit date:2006-07-25
Release date:2006-09-19
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Synergism Between Halide Binding and Proton Transport in a CLC-type Exchanger.
J.Mol.Biol., 362, 2006
2HTK
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BU of 2htk by Molmil
Structure of the Escherichia coli ClC chloride channel Y445A mutant and Fab complex
Descriptor: BROMIDE ION, Fab fragment, Heavy chain, ...
Authors:Accardi, A, Lobet, S, Williams, C, Miller, C, Dutzler, R.
Deposit date:2006-07-26
Release date:2006-09-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.41 Å)
Cite:Synergism between halide binding and proton transport in a CLC-type exchanger
J.Mol.Biol., 362, 2006
2HTL
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BU of 2htl by Molmil
Structure of the Escherichia coli ClC chloride channel Y445F mutant and Fab complex
Descriptor: BROMIDE ION, Fab fragment, Heavy chain, ...
Authors:Accardi, A, Lobet, S, Williams, C, Miller, C, Dutzler, R.
Deposit date:2006-07-26
Release date:2006-09-19
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Synergism Between Halide Binding and Proton Transport in a CLC-type Exchanger.
J.Mol.Biol., 362, 2006
2J9L
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BU of 2j9l by Molmil
Cytoplasmic Domain of the Human Chloride Transporter ClC-5 in complex with ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE CHANNEL PROTEIN 5, CHLORIDE ION
Authors:Meyer, S, Savaresi, S, Forster, I.C, Dutzler, R.
Deposit date:2006-11-13
Release date:2007-01-04
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Nucleotide Recognition by the Cytoplasmic Domain of the Human Chloride Transporter Clc-5
Nat.Struct.Mol.Biol., 14, 2006
1A8G
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BU of 1a8g by Molmil
HIV-1 PROTEASE IN COMPLEX WITH SDZ283-910
Descriptor: HIV-1 PROTEASE, benzyl [(1R)-1-({(1S,2S,3S)-1-benzyl-2-hydroxy-4-({(1S)-1-[(2-hydroxy-4-methoxybenzyl)carbamoyl]-2-methylpropyl}amino)-3-[(4-methoxybenzyl)amino]-4-oxobutyl}carbamoyl)-2,2-dimethylpropyl]carbamate
Authors:Kallen, J, Billich, A, Scholz, D, Auer, M, Kungl, A.
Deposit date:1998-03-24
Release date:1998-07-15
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:X-ray structure and conformational dynamics of the HIV-1 protease in complex with the inhibitor SDZ283-910: agreement of time-resolved spectroscopy and molecular dynamics simulations.
J.Mol.Biol., 286, 1999
5HEG
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BU of 5heg by Molmil
Pentameric ligand-gated ion channel GLIC mutant P246G
Descriptor: Proton-gated ion channel
Authors:Bertozzi, C, Hilf, R.J.C, Dtuzler, R.
Deposit date:2016-01-06
Release date:2016-03-02
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.214 Å)
Cite:Signal Transduction at the Domain Interface of Prokaryotic Pentameric Ligand-Gated Ion Channels.
Plos Biol., 14, 2016
7P60
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BU of 7p60 by Molmil
Structure of homomeric LRRC8A Volume-Regulated Anion Channel in complex with synthetic nanobody Sb4 at 1:0.5 ratio
Descriptor: Volume-regulated anion channel subunit LRRC8A, synthetic nanobody Sb4
Authors:Deneka, D, Rutz, S, Sawicka, M.
Deposit date:2021-07-15
Release date:2021-09-15
Last modified:2021-10-13
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Allosteric modulation of LRRC8 channels by targeting their cytoplasmic domains.
Nat Commun, 12, 2021
7P5V
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BU of 7p5v by Molmil
Structure of homomeric LRRC8A Volume-Regulated Anion Channel in complex with synthetic nanobody Sb1
Descriptor: Synthetic nanobody Sb1, Volume-regulated anion channel subunit LRRC8A
Authors:Deneka, D, Rutz, S, Sawicka, M.
Deposit date:2021-07-15
Release date:2021-09-15
Last modified:2021-10-13
Method:ELECTRON MICROSCOPY (3.06 Å)
Cite:Allosteric modulation of LRRC8 channels by targeting their cytoplasmic domains.
Nat Commun, 12, 2021
7P5Y
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BU of 7p5y by Molmil
Structure of homomeric LRRC8A Volume-Regulated Anion Channel in complex with synthetic nanobody Sb3
Descriptor: Volume-regulated anion channel subunit LRRC8A, synthetic nanobody Sb3
Authors:Deneka, D, Rutz, S, Sawicka, M.
Deposit date:2021-07-15
Release date:2021-09-15
Last modified:2021-10-13
Method:ELECTRON MICROSCOPY (3.29 Å)
Cite:Allosteric modulation of LRRC8 channels by targeting their cytoplasmic domains.
Nat Commun, 12, 2021
7P5W
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BU of 7p5w by Molmil
Structure of homomeric LRRC8A Volume-Regulated Anion Channel in complex with synthetic nanobody Sb2
Descriptor: Volume-regulated anion channel subunit LRRC8A, synthetic nanobody Sb2
Authors:Deneka, D, Rutz, S, Sawicka, M.
Deposit date:2021-07-15
Release date:2021-09-15
Last modified:2021-10-13
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Allosteric modulation of LRRC8 channels by targeting their cytoplasmic domains.
Nat Commun, 12, 2021
7P6K
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BU of 7p6k by Molmil
Structure of homomeric LRRC8A Volume-Regulated Anion Channel in complex with synthetic nanobody Sb5
Descriptor: Volume-regulated anion channel subunit LRRC8A, synthetic nanobody Sb5
Authors:Deneka, D, Rutz, S, Sawicka, M.
Deposit date:2021-07-16
Release date:2021-09-15
Last modified:2021-10-13
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Allosteric modulation of LRRC8 channels by targeting their cytoplasmic domains.
Nat Commun, 12, 2021
2FEC
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BU of 2fec by Molmil
Structure of the E203Q mutant of the Cl-/H+ exchanger CLC-ec1 from E.Coli
Descriptor: Fab fragment, heavy chain, light chain, ...
Authors:Accardi, A, Walden, M.P, Nguitragool, W, Jayaram, H, Williams, C, Miller, C.
Deposit date:2005-12-15
Release date:2006-01-03
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (3.967 Å)
Cite:Separate ion pathways in a Cl-/H+ exchanger
J.Gen.Physiol., 126, 2005
2FEE
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BU of 2fee by Molmil
Structure of the Cl-/H+ exchanger CLC-ec1 from E.Coli in NaBr
Descriptor: Fab fragment, heavy chain, light chain, ...
Authors:Accardi, A, Walden, M.P, Nguitragool, W, Jayaram, H, Williams, C, Miller, C.
Deposit date:2005-12-15
Release date:2006-01-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Separate ion pathways in a Cl-/H+ exchanger
J.Gen.Physiol., 126, 2005
2FED
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BU of 2fed by Molmil
Structure of the E203Q mutant of the Cl-/H+ exchanger CLC-ec1 from E.Coli
Descriptor: Fab fragment, heavy chain, light chain, ...
Authors:Accardi, A, Walden, M.P, Nguitragool, W, Jayaram, H, Williams, C, Miller, C.
Deposit date:2005-12-15
Release date:2006-01-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.317 Å)
Cite:Separate ion pathways in a Cl-/H+ exchanger
J.Gen.Physiol., 126, 2005

220113

数据于2024-05-22公开中

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