8E8M
 
 | | Mycobacterium tuberculosis RNAP paused elongation complex | | 分子名称: | DNA (54-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Delbeau, M, Darst, S.A, Campbell, E.A. | | 登録日 | 2022-08-25 | | 公開日 | 2023-03-22 | | 最終更新日 | 2023-10-11 | | 実験手法 | ELECTRON MICROSCOPY (3.13 Å) | | 主引用文献 | Structural and functional basis of the universal transcription factor NusG pro-pausing activity in Mycobacterium tuberculosis.
Mol.Cell, 83, 2023
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2Q1Z
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1OR7
 | | Crystal Structure of Escherichia coli sigmaE with the Cytoplasmic Domain of its Anti-sigma RseA | | 分子名称: | RNA polymerase sigma-E factor, Sigma-E factor negative regulatory protein | | 著者 | Campbell, E.A, Tupy, J.L, Gruber, T.M, Wang, S, Sharp, M.M, Gross, C.A, Darst, S.A. | | 登録日 | 2003-03-12 | | 公開日 | 2003-04-15 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of Escherichia coli sigmaE with the cytoplasmic domain of its anti-sigma RseA.
Mol.Cell, 11, 2003
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4OZ6
 | | Structure of the Branched Intermediate in Protein Splicing | | 分子名称: | ALA-MET-ARG-TYR, MAGNESIUM ION, Mxe gyrA intein | | 著者 | Bick, M.J, Liu, Z, Frutos, S, Vila-Perello, M, Debelouchina, G.T, Darst, S.A, Muir, T.W. | | 登録日 | 2014-02-14 | | 公開日 | 2014-05-14 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.786 Å) | | 主引用文献 | Structure of the branched intermediate in protein splicing.
Proc.Natl.Acad.Sci.USA, 111, 2014
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3D36
 | | How to Switch Off a Histidine Kinase: Crystal Structure of Geobacillus stearothermophilus KinB with the Inhibitor Sda | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Bick, M.J, Lamour, V, Rajashankar, K.R, Gordiyenko, Y, Robinson, C.V, Darst, S.A. | | 登録日 | 2008-05-09 | | 公開日 | 2009-01-13 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | How to switch off a histidine kinase: crystal structure of Geobacillus stearothermophilus KinB with the inhibitor Sda
J.Mol.Biol., 386, 2009
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1SIG
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5VI8
 | | Structure of a mycobacterium smegmatis transcription initiation complex with an upstream-fork promoter fragment | | 分子名称: | 1,2-ETHANEDIOL, DNA (26-MER), DNA (31-MER), ... | | 著者 | Hubin, E.A, Campbell, E.A, Darst, S.A. | | 登録日 | 2017-04-14 | | 公開日 | 2017-04-26 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.76 Å) | | 主引用文献 | Structural insights into the mycobacteria transcription initiation complex from analysis of X-ray crystal structures.
Nat Commun, 8, 2017
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5VT0
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2P7V
 | | Crystal structure of the Escherichia coli regulator of sigma 70, Rsd, in complex with sigma 70 domain 4 | | 分子名称: | MAGNESIUM ION, RNA polymerase sigma factor rpoD, Regulator of sigma D | | 著者 | Patikoglou, G.A, Westblade, L.F, Campbell, E.A, Lamour, V, Lane, W.J, Darst, S.A. | | 登録日 | 2007-03-20 | | 公開日 | 2007-08-21 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal structure of the Escherichia coli regulator of sigma70, Rsd, in complex with sigma70 domain 4.
J.Mol.Biol., 372, 2007
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1ZPQ
 | | STRUCTURE OF BACTERIOPHAGE LAMBDA CII protein | | 分子名称: | Regulatory protein CII | | 著者 | Jain, D, Kim, Y, Maxwell, K.L, Beasley, S, Gussin, G.N, Edwards, A.M, Joachimiak, A, Darst, S.A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2005-05-17 | | 公開日 | 2005-08-23 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal Structure of Bacteriophage lambdacII and Its DNA Complex.
Mol.Cell, 19, 2005
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1ZS4
 | | Structure of bacteriophage lambda cII protein in complex with DNA | | 分子名称: | DNA - 27mer, Regulatory protein CII | | 著者 | Jain, D, Kim, Y, Maxwell, K.L, Beasley, S, Gussin, G.N, Edwards, A.M, Darst, S.A. | | 登録日 | 2005-05-23 | | 公開日 | 2005-08-23 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal Structure of Bacteriophage lambdacII and Its DNA Complex.
Mol.Cell, 19, 2005
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2AUJ
 | | Structure of Thermus aquaticus RNA polymerase beta'-subunit insert | | 分子名称: | DNA-directed RNA polymerase beta' chain | | 著者 | Chlenov, M, Masuda, S, Murakami, K.S, Nikiforov, V, Darst, S.A, Mustaev, A. | | 登録日 | 2005-08-27 | | 公開日 | 2005-10-04 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structure and Function of Lineage-specific Sequence Insertions in the Bacterial RNA Polymerase beta' Subunit
J.Mol.Biol., 353, 2005
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2AUK
 | | Structure of E. coli RNA polymerase beta' G/G' insert | | 分子名称: | DNA-directed RNA polymerase beta' chain | | 著者 | Chlenov, M, Masuda, S, Murakami, K.S, Nikiforov, V, Darst, S.A, Mustaev, A. | | 登録日 | 2005-08-28 | | 公開日 | 2005-10-04 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure and Function of Lineage-specific Sequence Insertions in the Bacterial RNA Polymerase beta' Subunit
J.Mol.Biol., 353, 2005
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2H27
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2GHO
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2EYQ
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2ETN
 | | Crystal structure of Thermus aquaticus Gfh1 | | 分子名称: | anti-cleavage anti-GreA transcription factor Gfh1 | | 著者 | Lamour, V, Hogan, B.P, Erie, D.A, Darst, S.A. | | 登録日 | 2005-10-27 | | 公開日 | 2006-02-14 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Crystal structure of Thermus aquaticus Gfh1, a Gre-factor paralog that inhibits rather than stimulates transcript cleavage.
J.Mol.Biol., 356, 2006
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7MKE
 | | Cryo-EM structure of Escherichia coli RNA polymerase bound to lambda PR promoter DNA (class 2) | | 分子名称: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Saecker, R.M, Darst, S.A, Chen, J. | | 登録日 | 2021-04-23 | | 公開日 | 2021-09-29 | | 最終更新日 | 2021-10-13 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Structural origins of Escherichia coli RNA polymerase open promoter complex stability.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7MKJ
 | | Cryo-EM structure of Escherichia coli RNA polymerase bound to T7A1 promoter DNA | | 分子名称: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Saecker, R.M, Darst, S.A, Chen, J. | | 登録日 | 2021-04-23 | | 公開日 | 2021-09-29 | | 最終更新日 | 2021-10-13 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structural origins of Escherichia coli RNA polymerase open promoter complex stability.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7MKD
 | | Cryo-EM structure of Escherichia coli RNA polymerase bound to lambda PR promoter DNA (class 1) | | 分子名称: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Saecker, R.M, Darst, S.A, Chen, J. | | 登録日 | 2021-04-23 | | 公開日 | 2021-09-29 | | 最終更新日 | 2021-10-13 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural origins of Escherichia coli RNA polymerase open promoter complex stability.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7MKI
 | | Cryo-EM structure of Escherichia coli RNA polymerase bound to lambda PR (-5G to C) promoter DNA | | 分子名称: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Saecker, R.M, Darst, S.A, Chen, J. | | 登録日 | 2021-04-23 | | 公開日 | 2021-09-29 | | 最終更新日 | 2021-10-13 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structural origins of Escherichia coli RNA polymerase open promoter complex stability.
Proc.Natl.Acad.Sci.USA, 118, 2021
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6X50
 | | Mfd-bound E.coli RNA polymerase elongation complex - V state | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, DNA (64-MER), DNA-directed RNA polymerase subunit alpha, ... | | 著者 | Llewelyn, E, Chen, J, Kang, J.Y, Darst, S.A. | | 登録日 | 2020-05-24 | | 公開日 | 2021-02-03 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural basis for transcription complex disruption by the Mfd translocase.
Elife, 10, 2021
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6X4Y
 | | Mfd-bound E.coli RNA polymerase elongation complex - IV state | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA (64-MER), DNA-directed RNA polymerase subunit alpha, ... | | 著者 | Llewellyn, E, Chen, J, Kang, J.Y, Darst, S.A. | | 登録日 | 2020-05-24 | | 公開日 | 2021-02-03 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structural basis for transcription complex disruption by the Mfd translocase.
Elife, 10, 2021
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6X26
 | | Mfd-bound E.coli RNA polymerase elongation complex - L1 state | | 分子名称: | DNA (64-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Llewellyn, E, Chen, J, Kang, J.Y, Darst, S.A. | | 登録日 | 2020-05-20 | | 公開日 | 2021-02-03 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Structural basis for transcription complex disruption by the Mfd translocase.
Elife, 10, 2021
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6X43
 | | Mfd-bound E.coli RNA polymerase elongation complex - II state | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, DNA (64-MER), DNA-directed RNA polymerase subunit alpha, ... | | 著者 | Llewellyn, E, Chen, J, Kang, J.Y, Darst, S.A. | | 登録日 | 2020-05-22 | | 公開日 | 2021-02-03 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structural basis for transcription complex disruption by the Mfd translocase.
Elife, 10, 2021
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