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1AWO
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BU of 1awo by Molmil
THE SOLUTION NMR STRUCTURE OF ABL SH3 AND ITS RELATIONSHIP TO SH2 IN THE SH(32) CONSTRUCT, 20 STRUCTURES
分子名称: ABL TYROSINE KINASE
著者Cowburn, D.
登録日1997-10-03
公開日1998-01-28
最終更新日2022-02-16
実験手法SOLUTION NMR
主引用文献The solution structure of Abl SH3, and its relationship to SH2 in the SH(32) construct.
Structure, 3, 1995
1BAK
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BU of 1bak by Molmil
SIGNAL TRANSDUCTION PLECKSTRIN HOMOLOGY DOMAIN OF G-PROTEIN COUPLED RECEPTOR KINASE 2 (BETA-ADRENERGIC RECEPTOR KINASE 1), C-TERMINAL EXTENDED, NMR, 20 STRUCTURES
分子名称: G-PROTEIN COUPLED RECEPTOR KINASE 2
著者Fushman, D, Cowburn, D.
登録日1997-11-21
公開日1998-02-25
最終更新日2022-02-16
実験手法SOLUTION NMR
主引用文献The solution structure and dynamics of the pleckstrin homology domain of G protein-coupled receptor kinase 2 (beta-adrenergic receptor kinase 1). A binding partner of Gbetagamma subunits.
J.Biol.Chem., 273, 1998
1AB2
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THREE-DIMENSIONAL SOLUTION STRUCTURE OF THE SRC HOMOLOGY 2 DOMAIN OF C-ABL
分子名称: C-ABL TYROSINE KINASE SH2 DOMAIN
著者Overduin, M, Rios, C.B, Mayer, B.J, Baltimore, D, Cowburn, D.
登録日1993-07-19
公開日1994-01-31
最終更新日2022-02-16
実験手法SOLUTION NMR
主引用文献Three-dimensional solution structure of the src homology 2 domain of c-abl.
Cell(Cambridge,Mass.), 70, 1992
7SGT
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BU of 7sgt by Molmil
Domain III (EDIII) of the POWV E glycoprotein
分子名称: Envelope protein E
著者Harris, R, Cahill, S.M, Cowburn, D.
登録日2021-10-07
公開日2022-05-18
最終更新日2022-06-22
実験手法SOLUTION NMR
主引用文献A Powassan virus domain III nanoparticle immunogen elicits neutralizing and protective antibodies in mice.
Plos Pathog., 18, 2022
1C4B
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BU of 1c4b by Molmil
A BETA-HAIRPIN MIMIC FROM FCERI-ALPHA-CYCLO(RD-262)
分子名称: PROTEIN (CYCLO(RD-262))
著者Mcdonnell, J.M, Fushman, D, Cahill, S.M, Sutton, B.J, Cowburn, D.
登録日1999-08-02
公開日1999-08-25
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution Structures of FceRI Alpha-Chain Mimics: A Beta-Hairpin Peptide and Its Retroenantiomer
J.Am.Chem.Soc., 119, 1997
1A6S
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BU of 1a6s by Molmil
M-DOMAIN FROM GAG POLYPROTEIN OF ROUS SARCOMA VIRUS, NMR, 20 STRUCTURES
分子名称: GAG POLYPROTEIN
著者Mcdonnell, J.M, Fushman, D, Cahill, S.M, Zhou, W, Wolven, A, Wilson, C.B, Nelle, T.D, Resh, M.D, Wills, J, Cowburn, D.
登録日1998-03-02
公開日1998-10-14
最終更新日2022-02-16
実験手法SOLUTION NMR
主引用文献Solution structure and dynamics of the bioactive retroviral M domain from Rous sarcoma virus
J.Mol.Biol., 279, 1998
1Z66
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BU of 1z66 by Molmil
NMR solution structure of domain III of E-protein of tick-borne Langat flavivirus (no RDC restraints)
分子名称: Major envelope protein E
著者Mukherjee, M, Dutta, K, White, M.A, Cowburn, D, Fox, R.O.
登録日2005-03-21
公開日2006-03-28
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献NMR solution structure and backbone dynamics of domain III of the E protein of tick-borne Langat flavivirus suggests a potential site for molecular recognition.
Protein Sci., 15, 2006
1AWE
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BU of 1awe by Molmil
HUMAN SOS1 PLECKSTRIN HOMOLOGY (PH) DOMAIN, NMR, 20 STRUCTURES
分子名称: SOS1
著者Zheng, J, Cowburn, D.
登録日1997-10-01
公開日1998-02-25
最終更新日2022-02-16
実験手法SOLUTION NMR
主引用文献The solution structure of the pleckstrin homology domain of human SOS1. A possible structural role for the sequential association of diffuse B cell lymphoma and pleckstrin homology domains.
J.Biol.Chem., 272, 1997
6AX5
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BU of 6ax5 by Molmil
RPT1 region of INI1/SNF5/SMARCB1_HUMAN - SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1.
分子名称: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1
著者Girvin, M.E, Cahill, S.M, Harris, R, Cowburn, D, Spira, M, Wu, X, Prakash, R, Bernowitz, M, Almo, S.C, Kalpana, G.V.
登録日2017-09-06
公開日2017-10-18
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献INI1/SMARCB1 Rpt1 domain mimics TAR RNA in binding to integrase to facilitate HIV-1 replication.
Nat Commun, 12, 2021
5TVZ
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BU of 5tvz by Molmil
Solution NMR structure of Saccharomyces cerevisiae Pom152 Ig-like repeat, residues 718-820
分子名称: Nucleoporin POM152
著者Dutta, K, Sampathkumar, P, Cowburn, D, Almo, S.C, Rout, M.P, Fernandez-Martinez, J.
登録日2016-11-10
公開日2017-02-22
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Molecular Architecture of the Major Membrane Ring Component of the Nuclear Pore Complex.
Structure, 25, 2017
6DSL
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BU of 6dsl by Molmil
Consensus engineered intein (Cat) with atypical split site
分子名称: Consensus engineered intein CatC, Consensus engineered intein CatN
著者Sekar, G, Stevens, A.J, Muir, T.W, Cowburn, D.
登録日2018-06-14
公開日2018-09-19
最終更新日2020-01-01
実験手法SOLUTION NMR
主引用文献An Atypical Mechanism of Split Intein Molecular Recognition and Folding.
J. Am. Chem. Soc., 140, 2018
3EAC
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Crystal structure of SH2 domain of Human Csk (carboxyl-terminal src kinase), Oxidized form.
分子名称: Tyrosine-protein kinase CSK
著者Liu, D, Seidel, R.D, Cowburn, D.
登録日2008-08-25
公開日2009-11-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.37 Å)
主引用文献Combining biophysical methods to analyze the disulfide bond in SH2 domain of C-terminal Src kinase.
Biophys Rep, 2, 2016
3EAZ
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BU of 3eaz by Molmil
Crystal structure of SH2 domain of Human Csk (carboxyl-terminal src kinase), C122S mutant.
分子名称: Tyrosine-protein kinase CSK
著者Liu, D, Seidel, R.D, Cowburn, D.
登録日2008-08-26
公開日2009-11-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.31 Å)
主引用文献Combining biophysical methods to analyze the disulfide bond in SH2 domain of C-terminal Src kinase.
Biophys Rep, 2, 2016
1XBH
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BU of 1xbh by Molmil
A BETA-HAIRPIN MIMIC FROM FCERI-ALPHA-CYCLO(L-262)
分子名称: PROTEIN (CYCLO(L-262))
著者Mcdonnell, J.M, Fushman, D, Cahill, S.M, Sutton, B.J, Cowburn, D.
登録日1999-02-17
公開日1999-02-21
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution Structures of FceRI Alpha-Chain Mimics: A Beta-Hairpin Peptide and Its Retroenantiomer
J.Am.Chem.Soc., 119, 1997
1DDB
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BU of 1ddb by Molmil
STRUCTURE OF MOUSE BID, NMR, 20 STRUCTURES
分子名称: PROTEIN (BID)
著者Mcdonnell, J.M, Fushman, D, Milliman, C, Korsmeyer, S.J, Cowburn, D.
登録日1999-02-19
公開日1999-08-30
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution structure of the proapoptotic molecule BID: a structural basis for apoptotic agonists and antagonists.
Cell(Cambridge,Mass.), 96, 1999
3BRH
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BU of 3brh by Molmil
Protein Tyrosine Phosphatase PTPN-22 (Lyp) bound to the mono-Phosphorylated Lck active site peptide
分子名称: Lck Active Site Peptide, PHOSPHATE ION, Tyrosine-protein phosphatase non-receptor type 22
著者Seidel, R.D, Love, J, Piserchio, A, Cowburn, D.
登録日2007-12-21
公開日2009-02-17
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Lyp/PTPN22 Phosphatase Domain: Substrate Recognition and Specificity for Src family kinases
To be Published
2M0T
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BU of 2m0t by Molmil
Structural characterization of the extended PDZ1 domain from NHERF1
分子名称: Na(+)/H(+) exchange regulatory cofactor NHE-RF1
著者Bhattacharya, S, Ju, J.H, Cowburn, D, Bu, Z.
登録日2012-11-06
公開日2013-04-24
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Ligand-Induced Dynamic Changes in Extended PDZ Domains from NHERF1.
J.Mol.Biol., 425, 2013
2M0U
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BU of 2m0u by Molmil
Complex structure of C-terminal CFTR peptide and extended PDZ1 domain from NHERF1
分子名称: C-terminal CFTR peptide, Na(+)/H(+) exchange regulatory cofactor NHE-RF1
著者Bhattacharya, S, Ju, J.H, Cowburn, D, Bu, Z.
登録日2012-11-06
公開日2013-04-24
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Ligand-Induced Dynamic Changes in Extended PDZ Domains from NHERF1.
J.Mol.Biol., 425, 2013
2M0V
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BU of 2m0v by Molmil
Complex structure of C-terminal CFTR peptide and extended PDZ2 domain from NHERF1
分子名称: C-terminal CFTR peptide, Na(+)/H(+) exchange regulatory cofactor NHE-RF1
著者Bhattacharya, S, Ju, J.H, Cowburn, D, Bu, Z.
登録日2012-11-06
公開日2013-04-24
最終更新日2013-07-17
実験手法SOLUTION NMR
主引用文献Ligand-Induced Dynamic Changes in Extended PDZ Domains from NHERF1.
J.Mol.Biol., 425, 2013
2L6E
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BU of 2l6e by Molmil
NMR Structure of the monomeric mutant C-terminal domain of HIV-1 Capsid in complex with stapled peptide Inhibitor
分子名称: Capsid protein p24, NYAD-13 stapled peptide inhibitor
著者Bhattacharya, S, Zhang, H, Debnath, A.K, Cowburn, D.
登録日2010-11-18
公開日2010-12-29
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Solution structure of a hydrocarbon stapled peptide inhibitor in complex with monomeric C-terminal domain of HIV-1 capsid.
J.Biol.Chem., 283, 2008
1G84
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THE SOLUTION STRUCTURE OF THE C EPSILON2 DOMAIN FROM IGE
分子名称: IMMUNOGLOBULIN E
著者McDonnell, J.M, Cowburn, D, Gould, H.J, Sutton, B.J, Calvert, R, Beavil, R.E, Beavil, A.J, Henry, A.J.
登録日2000-11-16
公開日2001-05-16
最終更新日2021-10-27
実験手法SOLUTION NMR
主引用文献The structure of the IgE Cepsilon2 domain and its role in stabilizing the complex with its high-affinity receptor FcepsilonRIalpha.
Nat.Struct.Biol., 8, 2001
1JEG
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BU of 1jeg by Molmil
Solution structure of the SH3 domain from C-terminal Src Kinase complexed with a peptide from the tyrosine phosphatase PEP
分子名称: HEMATOPOIETIC CELL PROTEIN-TYROSINE PHOSPHATASE 70Z-PEP, TYROSINE-PROTEIN KINASE CSK
著者Ghose, R, Shekhtman, A, Goger, M.J, Ji, H, Cowburn, D.
登録日2001-06-17
公開日2001-10-31
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献A novel, specific interaction involving the Csk SH3 domain and its natural ligand.
Nat.Struct.Biol., 8, 2001
2GGR
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Solution structure of the C-terminal SH3 domain of c-CrkII
分子名称: Proto-oncogene C-crk
著者Muralidharan, V, Dutta, K, Muir, T.W, Cowburn, D.
登録日2006-03-24
公開日2006-08-01
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献Solution Structure and Folding Characteristics of the C-Terminal SH3 Domain of c-Crk-II
Biochemistry, 45, 2006
2GG1
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NMR solution structure of domain III of the E-protein of tick-borne Langat flavivirus (includes RDC restraints)
分子名称: Genome polyprotein
著者Mukherjee, M, Dutta, K, White, M.A, Cowburn, D, Fox, R.O.
登録日2006-03-23
公開日2006-04-25
最終更新日2023-11-29
実験手法SOLUTION NMR
主引用文献NMR solution structure and backbone dynamics of domain III of the E protein of tick-borne Langat flavivirus suggests a potential site for molecular recognition.
Protein Sci., 15, 2006
2K6X
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Autoregulation of a Group 1 Bacterial Sigma Factor Involves the Formation of a Region 1.1- Induced Compacted Structure
分子名称: RNA polymerase sigma factor rpoD
著者Schwartz, E.C, Shekhtman, A, Dutta, K, Pratt, M.R, Cowburn, D, Darst, S, Muir, T.W.
登録日2008-07-28
公開日2008-10-28
最終更新日2021-10-20
実験手法SOLUTION NMR
主引用文献Autoregulation of a Group 1 Bacterial Sigma Factor Involves the Formation of a Region 1.1 - Induced Compacted Structure
Chem.Biol., 15, 2008

 

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