2J0U
 
 | | The crystal structure of eIF4AIII-Barentsz complex at 3.0 A resolution | | Descriptor: | ATP-DEPENDENT RNA HELICASE DDX48, PROTEIN CASC3 | | Authors: | Bono, F, Ebert, J, Lorentzen, E, Conti, E. | | Deposit date: | 2006-08-04 | | Release date: | 2006-09-06 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | The Crystal Structure of the Exon Junction Complex Reveals How It Mantains a Stable Grip on Mrna
Cell(Cambridge,Mass.), 126, 2006
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2JA9
 | | Structure of the N-terminal deletion of yeast exosome component Rrp40 | | Descriptor: | EXOSOME COMPLEX EXONUCLEASE RRP40 | | Authors: | Oddone, A, Lorentzen, E, Basquin, J, Gasch, A, Rybin, V, Conti, E, Sattler, M. | | Deposit date: | 2006-11-24 | | Release date: | 2006-12-13 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural and Biochemical Characterization of the Yeast Exosome Component Rrp40
Embo Rep., 8, 2007
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2JEA
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2JEB
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2JE6
 | | Structure of a 9-subunit archaeal exosome | | Descriptor: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, EXOSOME COMPLEX EXONUCLEASE 1, ... | | Authors: | Lorentzen, E, Conti, E. | | Deposit date: | 2007-01-15 | | Release date: | 2007-01-23 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | RNA Channelling by the Archaeal Exosome.
Embo Rep., 8, 2007
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8BFJ
 | | CNOT11-GGNBP2 complex | | Descriptor: | 1,2-ETHANEDIOL, CCR4-NOT transcription complex subunit 11, Gametogenetin-binding protein 2 | | Authors: | Basquin, J, Ozgur, S, Conti, E. | | Deposit date: | 2022-10-26 | | Release date: | 2022-12-28 | | Last modified: | 2023-02-15 | | Method: | X-RAY DIFFRACTION (2.23 Å) | | Cite: | The human CNOT1-CNOT10-CNOT11 complex forms a structural platform for protein-protein interactions.
Cell Rep, 42, 2023
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8BFI
 | | human CNOT1-CNOT10-CNOT11 module | | Descriptor: | CCR4-NOT transcription complex subunit 1, CCR4-NOT transcription complex subunit 10, CCR4-NOT transcription complex subunit 11 | | Authors: | Basquin, J, Ozgur, S, Conti, E. | | Deposit date: | 2022-10-26 | | Release date: | 2022-12-28 | | Last modified: | 2023-02-15 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | The human CNOT1-CNOT10-CNOT11 complex forms a structural platform for protein-protein interactions.
Cell Rep, 42, 2023
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8BFH
 | | CNOT11 | | Descriptor: | CCR4-NOT transcription complex subunit 11 | | Authors: | Basquin, J, Ozgur, S, Conti, E. | | Deposit date: | 2022-10-26 | | Release date: | 2022-12-28 | | Last modified: | 2023-02-15 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | The human CNOT1-CNOT10-CNOT11 complex forms a structural platform for protein-protein interactions.
Cell Rep, 42, 2023
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1HL6
 | | A novel mode of RBD-protein recognition in the Y14-mago complex | | Descriptor: | CG8781 PROTEIN, MAGO NASHI PROTEIN | | Authors: | Fribourg, S, Gatfield, D, Yao, W, Izaurralde, E, Conti, E. | | Deposit date: | 2003-03-13 | | Release date: | 2003-05-08 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | A Novel Mode of Rbd-Protein Recognition in the Y14-Mago Complex
Nat.Struct.Biol., 10, 2003
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1JN5
 | | Structural basis for the recognition of a nucleoporin FG-repeat by the NTF2-like domain of TAP-p15 mRNA export factor | | Descriptor: | FG-repeat, TAP, p15 | | Authors: | Fribourg, S, Braun, I.C, Izaurralde, E, Conti, E. | | Deposit date: | 2001-07-23 | | Release date: | 2001-10-17 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural basis for the recognition of a nucleoporin FG repeat by the NTF2-like domain of the TAP/p15 mRNA nuclear export factor.
Mol.Cell, 8, 2001
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1JKG
 | | Structural basis for the recognition of a nucleoporin FG-repeat by the NTF2-like domain of TAP-p15 mRNA nuclear export factor | | Descriptor: | TAP, p15 | | Authors: | Fribourg, S, Braun, I.C, Izaurralde, E, Conti, E. | | Deposit date: | 2001-07-12 | | Release date: | 2001-10-17 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural basis for the recognition of a nucleoporin FG repeat by the NTF2-like domain of the TAP/p15 mRNA nuclear export factor.
Mol.Cell, 8, 2001
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2J0B
 | | Structure of the catalytic domain of mouse Manic Fringe in complex with UDP and manganese | | Descriptor: | BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE MANIC FRINGE, MANGANESE (II) ION, POTASSIUM ION, ... | | Authors: | Jinek, M, Chen, Y.-W, Clausen, H, Cohen, S.M, Conti, E. | | Deposit date: | 2006-08-01 | | Release date: | 2006-09-04 | | Last modified: | 2019-10-16 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural Insights Into the Notch-Modifying Glycosyltransferase Fringe
Nat.Struct.Mol.Biol., 13, 2006
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5OOQ
 | | Structure of the Mtr4 Nop53 Complex | | Descriptor: | ATP-dependent RNA helicase DOB1, Ribosome biogenesis protein NOP53, SULFATE ION | | Authors: | Falk, S, Basquin, J, Conti, E. | | Deposit date: | 2017-08-08 | | Release date: | 2017-09-20 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structural insights into the interaction of the nuclear exosome helicase Mtr4 with the preribosomal protein Nop53.
RNA, 23, 2017
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5AIE
 | | Not4 ring domain in complex with Ubc4 | | Descriptor: | GENERAL NEGATIVE REGULATOR OF TRANSCRIPTION SUBUNIT 4, UBIQUITIN-CONJUGATING ENZYME E2 4, ZINC ION | | Authors: | Bhaskar, V, Basquin, J, Conti, E. | | Deposit date: | 2015-02-12 | | Release date: | 2015-04-29 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Architecture of the Ubiquitylation Module of the Yeast Ccr4-not Complex.
Structure, 23, 2015
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5AJD
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5ANR
 | | Structure of a human 4E-T - DDX6 - CNOT1 complex | | Descriptor: | CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TRANSPORTER, PROBABLE ATP-DEPENDENT RNA HELICASE DDX6 | | Authors: | Basquin, J, Oezguer, S, Conti, E. | | Deposit date: | 2015-09-08 | | Release date: | 2015-10-21 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.102 Å) | | Cite: | Structure of a Human 4E-T/Ddx6/Cnot1 Complex Reveals the Different Interplay of Ddx6-Binding Proteins with the Ccr4-not Complex.
Cell Rep., 13, 2015
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1A0D
 | | XYLOSE ISOMERASE FROM BACILLUS STEAROTHERMOPHILUS | | Descriptor: | MANGANESE (II) ION, XYLOSE ISOMERASE | | Authors: | Gallay, O, Chopra, R, Conti, E, Brick, P, Blow, D. | | Deposit date: | 1997-11-28 | | Release date: | 1998-06-03 | | Last modified: | 2023-08-02 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Crystal Structures of Class II Xylose Isomerases from Two Thermophiles and a Hyperthermophile
To be Published
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1A0C
 | | XYLOSE ISOMERASE FROM THERMOANAEROBACTERIUM THERMOSULFURIGENES | | Descriptor: | COBALT (II) ION, XYLOSE ISOMERASE | | Authors: | Gallay, O, Chopra, R, Conti, E, Brick, P, Blow, D. | | Deposit date: | 1997-11-28 | | Release date: | 1998-06-03 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal Structures of Class II Xylose Isomerases from Two Thermophiles and a Hyperthermophile
To be Published
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5AOR
 | | Structure of MLE RNA ADP AlF4 complex | | Descriptor: | 5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP)-3', ADENOSINE-5'-DIPHOSPHATE, DOSAGE COMPENSATION REGULATOR, ... | | Authors: | Prabu, J.R, Conti, E. | | Deposit date: | 2015-09-11 | | Release date: | 2015-11-18 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.08 Å) | | Cite: | Structure of the RNA Helicase Mle Reveals the Molecular Mechanisms for Uridine Specificity and RNA-ATP Coupling.
Mol.Cell, 60, 2015
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2QFA
 | | Crystal structure of a Survivin-Borealin-INCENP core complex | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Baculoviral IAP repeat-containing protein 5, Borealin, ... | | Authors: | Jeyaprakash, A.A, Klein, U.R, Lindner, D, Ebert, J, Nigg, E.A, Conti, E. | | Deposit date: | 2007-06-27 | | Release date: | 2007-11-06 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Structure of a Survivin-Borealin-INCENP Core Complex Reveals How Chromosomal Passengers Travel Together.
Cell(Cambridge,Mass.), 131, 2007
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2X1G
 | | Crystal structure of Importin13 - Mago-Y14 complex | | Descriptor: | CADMUS, PROTEIN MAGO NASHI, RNA-BINDING PROTEIN 8A | | Authors: | Bono, F, Cook, A.G, Gruenwald, M, Ebert, J, Conti, E. | | Deposit date: | 2009-12-23 | | Release date: | 2010-02-16 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3.35 Å) | | Cite: | Nuclear Import Mechanism of the Ejc Component Mago- Y14 Revealed by Structural Studies of Importin 13.
Mol.Cell, 37, 2010
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2X19
 | | Crystal structure of Importin13 - RanGTP complex | | Descriptor: | GTP-BINDING NUCLEAR PROTEIN GSP1/CNR1, GUANOSINE-5'-TRIPHOSPHATE, IMPORTIN-13, ... | | Authors: | Bono, F, Cook, A.G, Gruenwald, M, Ebert, J, Conti, E. | | Deposit date: | 2009-12-23 | | Release date: | 2010-02-16 | | Last modified: | 2017-06-28 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Nuclear Import Mechanism of the Ejc Component Mago- Y14 Revealed by Structural Studies of Importin 13.
Mol.Cell, 37, 2010
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2XB2
 | | Crystal structure of the core Mago-Y14-eIF4AIII-Barentsz-UPF3b assembly shows how the EJC is bridged to the NMD machinery | | Descriptor: | EUKARYOTIC INITIATION FACTOR 4A-III, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | Authors: | Buchwald, G, Ebert, J, Basquin, C, Sauliere, J, Jayachandran, U, Bono, F, Le Hir, H, Conti, E. | | Deposit date: | 2010-04-03 | | Release date: | 2010-05-12 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Insights Into the Recruitment of the Nmd Machinery from the Crystal Structure of a Core Ejc-Upf3B Complex.
Proc.Natl.Acad.Sci.USA, 107, 2010
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2XZO
 | | Upf1 helicase - RNA complex | | Descriptor: | 5'-R(*UP*UP*UP*UP*UP*UP*UP)-3', ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Chakrabarti, S, Jayachandran, U, Bonneau, F, Fiorini, F, Basquin, C, Domcke, S, Le Hir, H, Conti, E. | | Deposit date: | 2010-11-26 | | Release date: | 2011-03-30 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.395 Å) | | Cite: | Molecular Mechanisms for the RNA-Dependent ATPase Activity of Upf1 and its Regulation by Upf2.
Mol.Cell, 41, 2011
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2J0A
 | | Structure of the catalytic domain of mouse Manic Fringe | | Descriptor: | BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE MANIC FRINGE, POTASSIUM ION, SULFATE ION | | Authors: | Jinek, M, Chen, Y.-W, Clausen, H, Cohen, S.M, Conti, E. | | Deposit date: | 2006-08-01 | | Release date: | 2006-09-04 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural Insights Into the Notch-Modifying Glycosyltransferase Fringe
Nat.Struct.Mol.Biol., 13, 2006
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