6UXM
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6UXR
| Crystal structure of BAK core domain BH3-groove-dimer in complex with LysoPC | 分子名称: | Bcl-2 homologous antagonist/killer, TETRAETHYLENE GLYCOL, TRIETHYLENE GLYCOL, ... | 著者 | Cowan, A.D, Colman, P.M, Czabotar, P.E. | 登録日 | 2019-11-07 | 公開日 | 2020-09-02 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | BAK core dimers bind lipids and can be bridged by them. Nat.Struct.Mol.Biol., 27, 2020
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5VWV
| Bak core latch dimer in complex with Bim-BH3 - Cubic | 分子名称: | 1,2-ETHANEDIOL, Bcl-2 homologous antagonist/killer, Bcl-2-like protein 11, ... | 著者 | Brouwer, J.M, Colman, P.M, Czabotar, P.E. | 登録日 | 2017-05-23 | 公開日 | 2017-11-15 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.897 Å) | 主引用文献 | Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design. Mol. Cell, 68, 2017
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5VX2
| Mcl-1 in complex with Bim-h3Pc-RT | 分子名称: | 1,2-ETHANEDIOL, Bcl-2-like protein 11, Induced myeloid leukemia cell differentiation protein Mcl-1 homolog,Induced myeloid leukemia cell differentiation protein Mcl-1 chimera | 著者 | Cowan, A.D, Brouwer, J.M, Colman, P.M, Czabotar, P.E. | 登録日 | 2017-05-23 | 公開日 | 2017-11-15 | 最終更新日 | 2020-01-08 | 実験手法 | X-RAY DIFFRACTION (1.851 Å) | 主引用文献 | Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design. Mol. Cell, 68, 2017
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5VX1
| Bak L100A | 分子名称: | Bcl-2 homologous antagonist/killer | 著者 | Brouwer, J.M, Colman, P.M, Czabotar, P.E. | 登録日 | 2017-05-23 | 公開日 | 2017-11-15 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.224 Å) | 主引用文献 | Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design. Mol. Cell, 68, 2017
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5VX0
| Bak in complex with Bim-h3Glg | 分子名称: | 1,2-ETHANEDIOL, Bcl-2 homologous antagonist/killer, Bcl-2-like protein 11, ... | 著者 | Brouwer, J.M, Lan, P, Lessene, G, Colman, P.M, Czabotar, P.E. | 登録日 | 2017-05-23 | 公開日 | 2017-11-15 | 最終更新日 | 2020-01-08 | 実験手法 | X-RAY DIFFRACTION (1.599 Å) | 主引用文献 | Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design. Mol. Cell, 68, 2017
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5VWW
| Bak core latch dimer in complex with Bim-RT - Tetragonal | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, BROMIDE ION, Bcl-2 homologous antagonist/killer, ... | 著者 | Brouwer, J.M, Colman, P.M, Czabotar, P.E. | 登録日 | 2017-05-23 | 公開日 | 2017-11-15 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.802 Å) | 主引用文献 | Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design. Mol. Cell, 68, 2017
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5W62
| Crystal structure of mouse BAX monomer | 分子名称: | Apoptosis regulator BAX, SULFATE ION | 著者 | Robin, A.Y, Colman, P.M, Czabotar, P.E, Luo, C.S. | 登録日 | 2017-06-16 | 公開日 | 2018-06-27 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.196 Å) | 主引用文献 | Ensemble Properties of Bax Determine Its Function. Structure, 26, 2018
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5VWZ
| Bak in complex with Bim-h3Pc | 分子名称: | 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, AMMONIUM ION, Bcl-2 homologous antagonist/killer, ... | 著者 | Brouwer, J.M, Colman, P.M, Czabotar, P.E. | 登録日 | 2017-05-23 | 公開日 | 2017-11-15 | 最終更新日 | 2020-01-08 | 実験手法 | X-RAY DIFFRACTION (1.622 Å) | 主引用文献 | Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design. Mol. Cell, 68, 2017
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5VWY
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5VX3
| Bcl-xL in complex with Bim-h3Pc-RT | 分子名称: | 1,2-ETHANEDIOL, Bcl-2-like protein 1, Bcl-2-like protein 11 | 著者 | Cowan, A.D, Brouwer, J.M, Colman, P.M, Czabotar, P.E. | 登録日 | 2017-05-23 | 公開日 | 2017-11-15 | 最終更新日 | 2020-01-08 | 実験手法 | X-RAY DIFFRACTION (1.945 Å) | 主引用文献 | Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design. Mol. Cell, 68, 2017
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5W5X
| Crystal structure of BAXP168G in complex with an activating antibody | 分子名称: | 1,2-ETHANEDIOL, 3C10 Fab' heavy chain, 3C10 Fab' light chain, ... | 著者 | Robin, A.Y, Colman, P.M, Czabotar, P.E. | 登録日 | 2017-06-16 | 公開日 | 2018-06-27 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.502 Å) | 主引用文献 | Ensemble Properties of Bax Determine Its Function. Structure, 26, 2018
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5VWX
| Bak core latch dimer in complex with Bim-h0-h3Glt | 分子名称: | 1,2-ETHANEDIOL, Bcl-2 homologous antagonist/killer, Bcl-2-like protein 11 | 著者 | Brouwer, J.M, Lan, P, Lessene, G, Colman, P.M, Czabotar, P.E. | 登録日 | 2017-05-23 | 公開日 | 2017-11-15 | 最終更新日 | 2020-01-08 | 実験手法 | X-RAY DIFFRACTION (2.489 Å) | 主引用文献 | Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design. Mol. Cell, 68, 2017
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5W5Z
| Crystal structure of BAXP168G in complex with an activating antibody at high resolution | 分子名称: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3C10 Fab heavy chain, ... | 著者 | Robin, A.Y, Colman, P.M, Czabotar, P.E. | 登録日 | 2017-06-16 | 公開日 | 2018-06-27 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.997 Å) | 主引用文献 | Ensemble Properties of Bax Determine Its Function. Structure, 26, 2018
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5W60
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5W61
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5W63
| Crystal structure of channel catfish BAX | 分子名称: | 1,2-ETHANEDIOL, Apoptosis regulator bax, SULFATE ION | 著者 | Robin, A.Y, Colman, P.M, Czabotar, P.E, Luo, C.S. | 登録日 | 2017-06-16 | 公開日 | 2018-06-27 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.436 Å) | 主引用文献 | Ensemble Properties of Bax Determine Its Function. Structure, 26, 2018
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1F8C
| Native Influenza Neuraminidase in Complex with 4-amino-2-deoxy-2,3-dehydro-N-neuraminic Acid | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-AMINO-2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, ... | 著者 | Smith, B.J, Colman, P.M, Von Itzstein, M, Danylec, B, Varghese, J.N. | 登録日 | 2000-06-30 | 公開日 | 2001-04-11 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Analysis of inhibitor binding in influenza virus neuraminidase. Protein Sci., 10, 2001
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1F8D
| Native Influenza Neuraminidase in Complex with 9-amino-2-deoxy-2,3-dehydro-N-neuraminic Acid | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 9-AMINO-2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, ... | 著者 | Smith, B.J, Colman, P.M, Von Itzstein, M, Danylec, B, Varghese, J.N. | 登録日 | 2000-06-30 | 公開日 | 2001-04-11 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Analysis of inhibitor binding in influenza virus neuraminidase. Protein Sci., 10, 2001
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1F8E
| Native Influenza Neuraminidase in Complex with 4,9-diamino-2-deoxy-2,3-dehydro-N-acetyl-neuraminic Acid | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4,9-AMINO-2,4-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, CALCIUM ION, ... | 著者 | Smith, B.J, Colman, P.M, Von Itzstein, M, Danylec, B, Varghese, J.N. | 登録日 | 2000-06-30 | 公開日 | 2001-04-11 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Analysis of inhibitor binding in influenza virus neuraminidase. Protein Sci., 10, 2001
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2V6Q
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2VTY
| Vaccinia virus anti-apoptotic F1L is a novel Bcl-2-like domain swapped dimer | 分子名称: | PROTEIN F1 | 著者 | Kvansakul, M, Yang, H, Fairlie, W.D, Czabotar, P.E, Fischer, S.F, Perugini, M.A, Huang, D.C.S, Colman, P.M. | 登録日 | 2008-05-19 | 公開日 | 2008-06-24 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Vaccinia Virus Anti-Apoptotic F1L is a Novel Bcl-2-Like Domain-Swapped Dimer that Binds a Highly Selective Subset of Bh3-Containing Death Ligands. Cell Death Differ., 15, 2008
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2WBF
| Crystal Structure Analysis of SERA5E from plasmodium falciparum with loop 690-700 ordered | 分子名称: | CALCIUM ION, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | 著者 | Smith, B.J, Malby, R.L, Colman, P.M, Clarke, O.B. | 登録日 | 2009-02-27 | 公開日 | 2009-03-31 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural insights into the protease-like antigen Plasmodium falciparum SERA5 and its noncanonical active-site serine. J. Mol. Biol., 392, 2009
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2WH6
| Crystal structure of anti-apoptotic BHRF1 in complex with the Bim BH3 domain | 分子名称: | BCL-2-LIKE PROTEIN 11, BROMIDE ION, EARLY ANTIGEN PROTEIN R, ... | 著者 | Kvansakul, M, Huang, D.C.S, Colman, P.M. | 登録日 | 2009-05-01 | 公開日 | 2010-05-26 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structural basis for apoptosis inhibition by Epstein-Barr virus BHRF1. PLoS Pathog., 6, 2010
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1L7H
| Crystal structure of R292K mutant influenza virus neuraminidase in complex with BCX-1812 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(1-ACETYLAMINO-2-ETHYL-BUTYL)-4-GUANIDINO-2-HYDROXY-CYCLOPENTANECARBOXYLIC ACID, ... | 著者 | Smith, B.J, McKimm-Breshkin, J.L, McDonald, M, Fernley, R.T, Varghese, J.N, Colman, P.M. | 登録日 | 2002-03-15 | 公開日 | 2002-05-29 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structural studies of the resistance of influenza virus neuramindase to inhibitors. J.Med.Chem., 45, 2002
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