1C8J
| CRYSTAL STRUCTURE OF CYTOCHROME P450CAM MUTANT (F87W/Y96F) | 分子名称: | CYTOCHROME P450-CAM, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Liu, Y, Jiang, F, Guo, Q, Chen, X, Jin, J, Sun, Y, Rao, Z. | 登録日 | 2000-05-31 | 公開日 | 2001-05-09 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal Structure of Cytochrome P450cam mutant (F87W/Y96F) To be Published
|
|
5KOC
| Pavine N-methyltransferase in complex with S-adenosylmethionine pH 7 | 分子名称: | Pavine N-methyltransferase, S-ADENOSYLMETHIONINE | 著者 | Torres, M.A, Hoffarth, E, Savtchouk, J, Chen, X, Morris, J, Facchini, P.J, Ng, K.K.S. | 登録日 | 2016-06-30 | 公開日 | 2016-09-07 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.293 Å) | 主引用文献 | Structural and Functional Studies of Pavine N-Methyltransferase from Thalictrum flavum Reveal Novel Insights into Substrate Recognition and Catalytic Mechanism. J.Biol.Chem., 291, 2016
|
|
5KOK
| Pavine N-methyltransferase in complex with Tetrahydropapaverine and S-adenosylhomocysteine pH 7.25 | 分子名称: | (1~{R})-1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline, (1~{S})-1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline, Pavine N-methyltransferase, ... | 著者 | Torres, M.A, Hoffarth, E, Eugenio, L, Savtchouk, J, Chen, X, Morris, J, Facchini, P.J, Ng, K.K.S. | 登録日 | 2016-06-30 | 公開日 | 2016-09-07 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.792 Å) | 主引用文献 | Structural and Functional Studies of Pavine N-Methyltransferase from Thalictrum flavum Reveal Novel Insights into Substrate Recognition and Catalytic Mechanism. J.Biol.Chem., 291, 2016
|
|
5KPC
| Pavine N-methyltransferase H206A mutant in complex with S-adenosylmethionine pH 6 | 分子名称: | Pavine N-methyltransferase, S-ADENOSYLMETHIONINE | 著者 | Torres, M.A, Hoffarth, E, Eugenio, L, Savtchouk, J, Chen, X, Morris, J, Facchini, P.J, Ng, K.K.S. | 登録日 | 2016-07-03 | 公開日 | 2016-09-07 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural and Functional Studies of Pavine N-Methyltransferase from Thalictrum flavum Reveal Novel Insights into Substrate Recognition and Catalytic Mechanism. J.Biol.Chem., 291, 2016
|
|
5KN4
| Pavine N-methyltransferase apoenzyme pH 6.0 | 分子名称: | Pavine N-methyltransferase | 著者 | Torres, M.A, Hoffarth, E, Eugenio, L, Savtchouk, J, Chen, X, Morris, J, Facchini, P.J, Ng, K.K.S. | 登録日 | 2016-06-27 | 公開日 | 2016-09-07 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Structural and Functional Studies of Pavine N-Methyltransferase from Thalictrum flavum Reveal Novel Insights into Substrate Recognition and Catalytic Mechanism. J.Biol.Chem., 291, 2016
|
|
5KPG
| Pavine N-methyltransferase in complex with S-adenosylhomocysteine pH 7 | 分子名称: | Pavine N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | 著者 | Torres, M.A, Hoffarth, E, Eugenio, L, Savtchouk, J, Chen, X, Morris, J, Facchini, P.J, Ng, K.K.S. | 登録日 | 2016-07-04 | 公開日 | 2016-09-07 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural and Functional Studies of Pavine N-Methyltransferase from Thalictrum flavum Reveal Novel Insights into Substrate Recognition and Catalytic Mechanism. J.Biol.Chem., 291, 2016
|
|
6IZJ
| Structural characterization of mutated NreA protein in nitrate binding site from Staphylococcus aureus | 分子名称: | 1,2-ETHANEDIOL, NITRATE ION, NreA | 著者 | Sangare, L, Chen, W, Wang, C, Chen, X, Wu, M, Zhang, X, Zang, J. | 登録日 | 2018-12-19 | 公開日 | 2020-01-22 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural insights into the conformational change of Staphylococcus aureus NreA at C-terminus. Biotechnol.Lett., 42, 2020
|
|
6K2H
| structural characterization of mutated NreA protein in nitrate binding site from staphylococcus aureus. | 分子名称: | 1,2-ETHANEDIOL, NreA | 著者 | Sangare, L, Chen, W, Wang, C, Chen, X, Wu, M, Zhang, X, Zang, J. | 登録日 | 2019-05-14 | 公開日 | 2020-03-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural insights into the conformational change of Staphylococcus aureus NreA at C-terminus. Biotechnol.Lett., 42, 2020
|
|
7RR5
| Structure of ribosomal complex bound with Rbg1/Tma46 | 分子名称: | 18S rRNA, 25S rRNA, 40S ribosomal protein S0, ... | 著者 | Zeng, F, Li, X, Pires-Alves, M, Chen, X, Hawk, C.W, Jin, H. | 登録日 | 2021-08-09 | 公開日 | 2021-11-10 | 実験手法 | ELECTRON MICROSCOPY (3.23 Å) | 主引用文献 | Conserved heterodimeric GTPase Rbg1/Tma46 promotes efficient translation in eukaryotic cells. Cell Rep, 37, 2021
|
|
7RSL
| Seipin forms a flexible cage at lipid droplet formation sites | 分子名称: | Seipin | 著者 | Arlt, H, Sui, X, Folger, B, Adams, C, Chen, X, Remme, R, Hamprecht, F.A, DiMaio, F, Liao, M, Goodman, J.M, Farese Jr, R.V, Walther, T.C. | 登録日 | 2021-08-11 | 公開日 | 2022-02-09 | 最終更新日 | 2022-03-30 | 実験手法 | ELECTRON MICROSCOPY (3.45 Å) | 主引用文献 | Seipin forms a flexible cage at lipid droplet formation sites. Nat.Struct.Mol.Biol., 29, 2022
|
|
1QET
| TANDEM GU MISMATCHES IN RNA, NMR, 30 STRUCTURES | 分子名称: | RNA (5'-R(*GP*GP*AP*UP*GP*UP*CP*C)-3') | 著者 | Mcdowell, J.A, He, L, Chen, X, Turner, D.H. | 登録日 | 1997-03-04 | 公開日 | 1997-06-05 | 最終更新日 | 2022-03-02 | 実験手法 | SOLUTION NMR | 主引用文献 | Investigation of the structural basis for thermodynamic stabilities of tandem GU wobble pairs: NMR structures of (rGGAGUUCC)2 and (rGGAUGUCC)2. Biochemistry, 36, 1997
|
|
1QES
| TANDEM GU MISMATCHES IN RNA, NMR, 30 STRUCTURES | 分子名称: | RNA (5'-R(*GP*GP*AP*GP*UP*UP*CP*C)-3') | 著者 | Mcdowell, J.A, He, L, Chen, X, Turner, D.H. | 登録日 | 1997-03-04 | 公開日 | 1997-06-05 | 最終更新日 | 2022-03-02 | 実験手法 | SOLUTION NMR | 主引用文献 | Investigation of the structural basis for thermodynamic stabilities of tandem GU wobble pairs: NMR structures of (rGGAGUUCC)2 and (rGGAUGUCC)2. Biochemistry, 36, 1997
|
|
1R1V
| Crystal structure of the metal-sensing transcriptional repressor CzrA from Staphylococcus aureus in the Zn2-form | 分子名称: | ZINC ION, repressor protein | 著者 | Eicken, C, Pennella, M.A, Chen, X, Koshlap, K.M, VanZile, M.L, Sacchettini, J.C, Giedroc, D.P. | 登録日 | 2003-09-25 | 公開日 | 2004-05-18 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | A metal-ligand-mediated intersubunit allosteric switch in related SmtB/ArsR zinc sensor proteins. J.Mol.Biol., 333, 2003
|
|
1R22
| Crystal structure of the cyanobacterial metallothionein repressor SmtB (C14S/C61S/C121S mutant) in the Zn2alpha5-form | 分子名称: | Transcriptional repressor smtB, ZINC ION | 著者 | Eicken, C, Pennella, M.A, Chen, X, Koshlap, K.M, VanZile, M.L, Sacchettini, J.C, Giedroc, D.P. | 登録日 | 2003-09-25 | 公開日 | 2004-05-18 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | A metal-ligand-mediated intersubunit allosteric switch in related SmtB/ArsR zinc sensor proteins. J.Mol.Biol., 333, 2003
|
|
1R1U
| Crystal structure of the metal-sensing transcriptional repressor CzrA from Staphylococcus aureus in the apo-form | 分子名称: | repressor protein | 著者 | Eicken, C, Pennella, M.A, Chen, X, Koshlap, K.M, VanZile, M.L, Sacchettini, J.C, Giedroc, D.P. | 登録日 | 2003-09-25 | 公開日 | 2004-05-18 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A metal-ligand-mediated intersubunit allosteric switch in related SmtB/ArsR zinc sensor proteins. J.Mol.Biol., 333, 2003
|
|
1R23
| Crystal structure of the cyanobacterial metallothionein repressor SmtB in the Zn1-form (one Zn(II) per dimer) | 分子名称: | Transcriptional repressor smtB, ZINC ION | 著者 | Eicken, C, Pennella, M.A, Chen, X, Koshlap, K.M, VanZile, M.L, Sacchettini, J.C, Giedroc, D.P. | 登録日 | 2003-09-25 | 公開日 | 2004-05-18 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A metal-ligand-mediated intersubunit allosteric switch in related SmtB/ArsR zinc sensor proteins. J.Mol.Biol., 333, 2003
|
|
1R1T
| Crystal structure of the cyanobacterial metallothionein repressor SmtB in the apo-form | 分子名称: | Transcriptional repressor smtB | 著者 | Eicken, C, Pennella, M.A, Chen, X, Koshlap, K.M, VanZile, M.L, Sacchettini, J.C, Giedroc, D.P. | 登録日 | 2003-09-25 | 公開日 | 2004-05-18 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | A metal-ligand-mediated intersubunit allosteric switch in related SmtB/ArsR zinc sensor proteins. J.Mol.Biol., 333, 2003
|
|
1S8K
| Solution Structure of BmKK4, A Novel Potassium Channel Blocker from Scorpion Buthus martensii Karsch, 25 structures | 分子名称: | Toxin BmKK4 | 著者 | Zhang, N, Chen, X, Li, M, Cao, C, Wang, Y, Hu, G, Wu, H. | 登録日 | 2004-02-02 | 公開日 | 2005-02-08 | 最終更新日 | 2022-03-02 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of BmKK4, the first member of subfamily alpha-KTx 17 of scorpion toxins Biochemistry, 43, 2004
|
|
3G5C
| Structural and biochemical studies on the ectodomain of human ADAM22 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ADAM 22, CALCIUM ION | 著者 | Liu, H, Shim, A, Chen, X, He, X. | 登録日 | 2009-02-04 | 公開日 | 2009-08-18 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | 主引用文献 | Structural and biochemical studies on the ectodomain of human ADAM22 J.Biol.Chem., 2009
|
|
1MI8
| 2.0 Angstrom crystal structure of a DnaB intein from Synechocystis sp. PCC 6803 | 分子名称: | DnaB intein | 著者 | Ding, Y, Chen, X, Ferrandon, S, Xu, M, Rao, Z. | 登録日 | 2002-08-22 | 公開日 | 2003-08-19 | 最終更新日 | 2021-11-10 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of mini-intein reveals a conserved catalytic module involved in side chain cyclization of asparagine during protein splicing J.Biol.Chem., 278, 2003
|
|
1MPW
| Molecular Recognition in (+)-a-Pinene Oxidation by Cytochrome P450cam | 分子名称: | (+)-alpha-Pinene, CYTOCHROME P450CAM, POTASSIUM ION, ... | 著者 | Bell, S.G, Chen, X, Sowden, R.J, Xu, F, Willams, J.N, Wong, L.-L, Rao, Z. | 登録日 | 2002-09-13 | 公開日 | 2002-10-09 | 最終更新日 | 2021-11-10 | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | 主引用文献 | Molecular recognition in (+)-alpha-pinene oxidation by cytochrome P450cam J.Am.Chem.Soc., 125, 2003
|
|
2QVU
| Porcine Liver Fructose-1,6-bisphosphatase cocrystallized with Fru-2,6-P2 and Mg2+, I(T)-state | 分子名称: | 2,6-di-O-phosphono-beta-D-fructofuranose, Fructose-1,6-bisphosphatase 1, MAGNESIUM ION, ... | 著者 | Hines, J.K, Chen, X, Nix, J.C, Fromm, H.J, Honzatko, R.B. | 登録日 | 2007-08-08 | 公開日 | 2007-10-23 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structures of mammalian and bacterial fructose-1,6-bisphosphatase reveal the basis for synergism in AMP/fructose 2,6-bisphosphate inhibition J.Biol.Chem., 282, 2007
|
|
2QVV
| Porcine Liver Fructose-1,6-bisphosphatase cocrystallized with Fru-2,6-P2 and Zn2+, I(T)-state | 分子名称: | 2,6-di-O-phosphono-beta-D-fructofuranose, Fructose-1,6-bisphosphatase 1, PHOSPHATE ION, ... | 著者 | Hines, J.K, Chen, X, Nix, J.C, Fromm, H.J, Honzatko, R.B. | 登録日 | 2007-08-08 | 公開日 | 2007-10-23 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Structures of mammalian and bacterial fructose-1,6-bisphosphatase reveal the basis for synergism in AMP/fructose 2,6-bisphosphate inhibition J.Biol.Chem., 282, 2007
|
|
7CN9
| Cryo-EM structure of SARS-CoV-2 Spike ectodomain | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Ho, M, Chang, Y, Wang, C, Wu, Y, Huang, H, Chen, T, Lo, J.M, Chen, X, Ma, C. | 登録日 | 2020-07-30 | 公開日 | 2020-08-26 | 最終更新日 | 2021-03-10 | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | 主引用文献 | A Carbohydrate-Binding Protein from the Edible Lablab Beans Effectively Blocks the Infections of Influenza Viruses and SARS-CoV-2. Cell Rep, 32, 2020
|
|
6JPJ
| Crystal structure of FGF401 in complex of FGFR4 | 分子名称: | Fibroblast growth factor receptor 4, N-[5-cyano-4-(2-methoxyethylamino)pyridin-2-yl]-7-methanoyl-6-[(4-methyl-2-oxidanylidene-piperazin-1-yl)methyl]-3,4-dihydro-2H-1,8-naphthyridine-1-carboxamide, SULFATE ION | 著者 | Zhou, Z, Chen, X, Chen, Y. | 登録日 | 2019-03-27 | 公開日 | 2019-05-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.638 Å) | 主引用文献 | Characterization of FGF401 as a reversible covalent inhibitor of fibroblast growth factor receptor 4. Chem.Commun.(Camb.), 55, 2019
|
|