8C59
 
 | | CpG specific M.MpeI methyltransferase crystallized in the presence of 5-bromocytosine (converted to 5mC) and 5-methylcytosine containing dsDNA | | 分子名称: | CARBONATE ION, CITRIC ACID, Cytosine-specific methyltransferase, ... | | 著者 | Wojciechowski, M, Czapinska, H, Krwawicz, J, Rafalski, D, Bochtler, M. | | 登録日 | 2023-01-06 | | 公開日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Cytosine analogues as DNA methyltransferase substrates and inhibitors
To Be Published
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5LEO
 | | Complex structure of lysostaphin SH3b domain with peptidoglycan fragment | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, GLY-GLY-GLY-GLY-GLY, Lysostaphin, ... | | 著者 | Jagielska, E, Nowak, E, Bochtler, M, Sabala, I. | | 登録日 | 2016-06-30 | | 公開日 | 2017-07-12 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Complex structure of lysostaphin SH3doamin with peptidoglycan fragment
To Be Published
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3NDH
 | | Restriction endonuclease in complex with substrate DNA | | 分子名称: | ACETATE ION, CHLORIDE ION, DNA (5'-D(*C*CP*AP*TP*CP*GP*CP*GP*TP*AP*C)-3'), ... | | 著者 | Firczuk, M, Wojciechowski, M, Czapinska, H, Bochtler, M. | | 登録日 | 2010-06-07 | | 公開日 | 2010-07-28 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | DNA intercalation without flipping in the specific ThaI-DNA complex
Nucleic Acids Res., 39, 2011
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4KYW
 | | Restriction endonuclease DPNI in complex with two DNA molecules | | 分子名称: | 5'-(*DC*DTP*DGP*DGP*6MAP*DTP*DCP*DCP*DAP*DG)-3', CALCIUM ION, SODIUM ION, ... | | 著者 | Mierzejewska, K, Siwek, W, Czapinska, H, Skowronek, K, Bujnicki, J.M, Bochtler, M. | | 登録日 | 2013-05-29 | | 公開日 | 2014-06-04 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Structural basis of the methylation specificity of R.DpnI.
Nucleic Acids Res., 42, 2014
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2Q10
 | | RESTRICTION ENDONUCLEASE BcnI (WILD TYPE)-COGNATE DNA SUBSTRATE COMPLEX | | 分子名称: | CALCIUM ION, CHLORIDE ION, DNA (5'-D(*AP*AP*CP*CP*CP*GP*GP*AP*GP*AP*C)-3'), ... | | 著者 | Sokolowska, M, Kaus-Drobek, M, Czapinska, H, Tamulaitis, G, Szczepanowski, R.H, Urbanke, C, Siksnys, V, Bochtler, M. | | 登録日 | 2007-05-23 | | 公開日 | 2007-06-05 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Monomeric Restriction Endonuclease BcnI in the Apo Form and in an Asymmetric Complex with Target DNA.
J.Mol.Biol., 369, 2007
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1TZP
 | | MEPA, inactive form without ZN in P21 | | 分子名称: | 1,4-BUTANEDIOL, Penicillin-insensitive murein endopeptidase, SULFATE ION | | 著者 | Marcyjaniak, M, Odintsov, S.G, Sabala, I, Bochtler, M. | | 登録日 | 2004-07-11 | | 公開日 | 2004-09-07 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Peptidoglycan amidase MepA is a LAS metallopeptidase
J.Biol.Chem., 279, 2004
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6G3B
 | | AvaII restriction endonuclease in complex with an RNA/DNA hybrid | | 分子名称: | DNA (5'-D(*CP*CP*AP*TP*GP*GP*TP*CP*CP*TP*A)-3'), RNA (5'-R(P*GP*UP*AP*GP*GP*AP*CP*CP*AP*UP*G)-3'), Type II site-specific deoxyribonuclease | | 著者 | Kisiala, M, Kowalska, M, Czapinska, H, Bochtler, M. | | 登録日 | 2018-03-24 | | 公開日 | 2019-04-10 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Restriction endonucleases that cleave RNA/DNA heteroduplexes bind dsDNA in A-like conformation
Nucleic Acids Res., 2020
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4DKJ
 | | CpG specific methyltransferase in complex with target DNA | | 分子名称: | Cytosine-specific methyltransferase, DNA (5'-D(*CP*CP*AP*CP*AP*TP*GP*(C37)P*GP*CP*TP*GP*AP*A)-3'), DNA (5'-D(*GP*TP*TP*CP*AP*GP*(5CM)P*GP*CP*AP*TP*GP*TP*G)-3'), ... | | 著者 | Wojciechowski, M, Czapinska, H, Bochtler, M. | | 登録日 | 2012-02-03 | | 公開日 | 2012-12-05 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | CpG underrepresentation and the bacterial CpG-specific DNA methyltransferase M.MpeI.
Proc.Natl.Acad.Sci.USA, 110, 2013
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6S58
 | | AvaII restriction endonuclease in the absence of nucleic acids | | 分子名称: | CALCIUM ION, Type II site-specific deoxyribonuclease, UNKNOWN ATOM OR ION | | 著者 | Kisiala, M, Kowalska, M, Korza, H, Czapinska, H, Bochtler, M. | | 登録日 | 2019-06-30 | | 公開日 | 2020-05-20 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | | 主引用文献 | Restriction endonucleases that cleave RNA/DNA heteroduplexes bind dsDNA in A-like conformation.
Nucleic Acids Res., 48, 2020
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6S48
 | | AvaII RESTRICTION ENDONUCLEASE IN COMPLEX WITH PARTIALLY CLEAVED dsDNA | | 分子名称: | BETA-MERCAPTOETHANOL, CALCIUM ION, DNA (5'-D(*GP*AP*TP*G)-3'), ... | | 著者 | Kisiala, M, Kowalska, M, Korza, H, Czapinska, H, Bochtler, M. | | 登録日 | 2019-06-26 | | 公開日 | 2020-05-20 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Restriction endonucleases that cleave RNA/DNA heteroduplexes bind dsDNA in A-like conformation.
Nucleic Acids Res., 48, 2020
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6R64
 | | N-terminal domain of modification dependent EcoKMcrA restriction endonuclease (NEco) in complex with C5mCGG target sequence | | 分子名称: | 5-methylcytosine-specific restriction enzyme A, DNA (5'-D(*GP*AP*AP*CP*(5CM)P*GP*GP*TP*GP*A)-3'), DNA (5'-D(*TP*CP*AP*CP*(5CM)P*GP*GP*TP*TP*C)-3') | | 著者 | Slyvka, A, Zagorskaite, E, Czapinska, H, Sasnauskas, G, Bochtler, M. | | 登録日 | 2019-03-26 | | 公開日 | 2019-10-23 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | | 主引用文献 | Crystal structure of the EcoKMcrA N-terminal domain (NEco): recognition of modified cytosine bases without flipping.
Nucleic Acids Res., 47, 2019
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1PXV
 | | The staphostatin-staphopain complex: a forward binding inhibitor in complex with its target cysteine protease | | 分子名称: | GUANIDINE, SULFATE ION, cysteine protease, ... | | 著者 | Filipek, R, Rzychon, M, Oleksy, A, Gruca, M, Dubin, A, Potempa, J, Bochtler, M. | | 登録日 | 2003-07-07 | | 公開日 | 2003-10-21 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The Staphostatin-Staphopain Complex: A FORWARD BINDING INHIBITOR IN COMPLEX WITH ITS TARGET CYSTEINE PROTEASE.
J.Biol.Chem., 278, 2003
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6GHC
 | | Modification dependent EcoKMcrA restriction endonuclease | | 分子名称: | 5-methylcytosine-specific restriction enzyme A, ZINC ION | | 著者 | Czapinska, H, Kowalska, M, Zagorskaite, E, Manakova, E, Xu, S, Siksnys, V, Sasnauskas, G, Bochtler, M. | | 登録日 | 2018-05-07 | | 公開日 | 2018-08-08 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Activity and structure of EcoKMcrA.
Nucleic Acids Res., 46, 2018
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6GHS
 | | Modification dependent TagI restriction endonuclease | | 分子名称: | SODIUM ION, TagI restriction endonuclease, ZINC ION | | 著者 | Kisiala, M, Copelas, A, Czapinska, H, Xu, S, Bochtler, M. | | 登録日 | 2018-05-08 | | 公開日 | 2018-08-29 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.92 Å) | | 主引用文献 | Crystal structure of the modification-dependent SRA-HNH endonuclease TagI.
Nucleic Acids Res., 46, 2018
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1U10
 | | MEPA, active form with ZN in P1 | | 分子名称: | Penicillin-insensitive murein endopeptidase, SULFATE ION, ZINC ION | | 著者 | Marcyjaniak, M, Odintsov, S.G, Sabala, I, Bochtler, M. | | 登録日 | 2004-07-14 | | 公開日 | 2004-09-07 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Peptidoglycan amidase MepA is a LAS metallopeptidase
J.Biol.Chem., 279, 2004
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2ODH
 | | Restriction Endonuclease BCNI in the Absence of DNA | | 分子名称: | ACETATE ION, DI(HYDROXYETHYL)ETHER, R.BcnI | | 著者 | Sokolowska, M, Kaus-Drobek, M, Czapinska, H, Tamulaitis, G, Szczepanowski, R.H, Urbanke, K, Siksnys, V, Bochtler, M. | | 登録日 | 2006-12-22 | | 公開日 | 2007-03-20 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Monomeric restriction endonuclease BcnI in the apo form and in an asymmetric complex with target DNA.
J.Mol.Biol., 369, 2007
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2OA9
 | | Restriction endonuclease MvaI in the absence of DNA | | 分子名称: | ACETATE ION, CADMIUM ION, CHLORIDE ION, ... | | 著者 | Kaus-Drobek, M, Czapinska, H, Sokolowska, M, Tamulaitis, G, Szczepanowski, R.H, Urbanke, K, Siksnys, V, Bochtler, M. | | 登録日 | 2006-12-15 | | 公開日 | 2007-02-20 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Restriction endonuclease MvaI is a monomer that recognizes its target sequence asymmetrically.
Nucleic Acids Res., 35, 2007
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2ODI
 | | Restriction Endonuclease BCNI-Cognate DNA Substrate Complex | | 分子名称: | 5'-D(*AP*AP*CP*CP*CP*GP*GP*AP*GP*AP*C)-3', 5'-D(*CP*TP*CP*CP*GP*GP*GP*TP*TP*GP*T)-3', CALCIUM ION, ... | | 著者 | Sokolowska, M, Kaus-Drobek, M, Czapinska, H, Tamulaitis, G, Szczepanowski, R.H, Urbanke, C, Siksnys, V, Bochtler, M. | | 登録日 | 2006-12-22 | | 公開日 | 2007-03-20 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Monomeric restriction endonuclease BcnI in the apo form and in an asymmetric complex with target DNA.
J.Mol.Biol., 369, 2007
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2OAA
 | | Restriction endonuclease MvaI-cognate DNA substrate complex | | 分子名称: | 5'-D(*CP*AP*TP*CP*CP*AP*GP*GP*TP*AP*C)-3', 5'-D(*GP*GP*TP*AP*CP*CP*TP*GP*GP*AP*T)-3', CALCIUM ION, ... | | 著者 | Kaus-Drobek, M, Czapinska, H, Sokolowska, M, Tamulaitis, G, Szczepanowski, R.H, Urbanke, K, Siksnys, V, Bochtler, M. | | 登録日 | 2006-12-15 | | 公開日 | 2007-02-20 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Restriction endonuclease MvaI is a monomer that recognizes its target sequence asymmetrically.
Nucleic Acids Res., 35, 2007
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4OQ2
 | | 5hmC specific restriction endonuclease PvuRTs1I | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Restriction endonuclease PvuRts1 I | | 著者 | Kazrani, A.A, Kowalska, M, Czapinska, H, Bochtler, M. | | 登録日 | 2014-02-07 | | 公開日 | 2014-03-12 | | 最終更新日 | 2018-03-07 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Crystal structure of the 5hmC specific endonuclease PvuRts1I.
Nucleic Acids Res., 42, 2014
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3FC3
 | | Crystal structure of the beta-beta-alpha-Me type II restriction endonuclease Hpy99I | | 分子名称: | 5'-(*DCP*DTP*DCP*DGP*DAP*DCP*DGP*DTP*DAP*DGP*DA)-3', 5'-(*DTP*DAP*DCP*DGP*DTP*DCP*DGP*DAP*DGP*DTP*DC)-3', Restriction endonuclease Hpy99I, ... | | 著者 | Sokolowska, M, Czapinska, H, Bochtler, M. | | 登録日 | 2008-11-21 | | 公開日 | 2009-03-31 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Crystal structure of the beta beta alpha-Me type II restriction endonuclease Hpy99I with target DNA.
Nucleic Acids Res., 37, 2009
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3GOX
 | | Crystal structure of the beta-beta-alpha-Me type II restriction endonuclease Hpy99I in the absence of EDTA | | 分子名称: | 5'-(*DCP*DTP*DCP*DGP*DAP*DCP*DGP*DTP*DAP*DGP*DA)-3', 5'-(*DTP*DAP*DCP*DGP*DTP*DCP*DGP*DAP*DGP*DTP*DC)-3', PENTAETHYLENE GLYCOL, ... | | 著者 | Sokolowska, M, Czapinska, H, Bochtler, M. | | 登録日 | 2009-03-20 | | 公開日 | 2009-04-28 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Crystal structure of the beta beta alpha-Me type II restriction endonuclease Hpy99I with target DNA.
Nucleic Acids Res., 37, 2009
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1OH1
 | | Solution structure of staphostatin A form Staphylococcus aureus confirms the discovery of a novel class of cysteine proteinase inhibitors. | | 分子名称: | STAPHOSTATIN A | | 著者 | Dubin, G, Popowicz, G, Krajewski, M, Stec, J, Bochtler, M, Potempa, J, Dubin, A, Holak, T.A. | | 登録日 | 2003-05-21 | | 公開日 | 2003-11-20 | | 最終更新日 | 2011-07-13 | | 実験手法 | SOLUTION NMR | | 主引用文献 | A Novel Class of Cysteine Protease Inhibitors: Solution Structure of Staphostatin a from Staphylococcus Aureus
Biochemistry, 42, 2003
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4ESJ
 | | RESTRICTION ENDONUCLEASE DpnI IN COMPLEX WITH TARGET DNA | | 分子名称: | AZIDE ION, DNA (5'-D(*CP*TP*GP*GP*(6MA)P*TP*CP*CP*AP*G)-3'), GLYCEROL, ... | | 著者 | Siwek, W, Czapinska, H, Bochtler, M, Bujnicki, J.M, Skowronek, K. | | 登録日 | 2012-04-23 | | 公開日 | 2012-06-13 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Crystal structure and mechanism of action of the N6-methyladenine-dependent type IIM restriction endonuclease R.DpnI.
Nucleic Acids Res., 40, 2012
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1NYC
 | | Staphostatins resemble lipocalins, not cystatins in fold. | | 分子名称: | CHLORIDE ION, SULFATE ION, cysteine protease inhibitor | | 著者 | Rzychon, M, Filipek, R, Sabat, A, Kosowska, K, Dubin, A, Potempa, J, Bochtler, M. | | 登録日 | 2003-02-12 | | 公開日 | 2003-09-30 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Staphostatins resemble lipocalins, not cystatins in fold.
Protein Sci., 12, 2003
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