3R6C
 
 | | Anthranilate phosphoribosyltransferase (trpD) from Mycobacterium tuberculosis (complex with inhibitor ACS179) | | 分子名称: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 8-methoxyphenanthro[3,4-d][1,3]dioxole-5,6-dicarboxylic acid, Anthranilate phosphoribosyltransferase, ... | | 著者 | Castell, A, Short, F.L, Lott, J.S, TB Structural Genomics Consortium (TBSGC) | | 登録日 | 2011-03-21 | | 公開日 | 2012-09-26 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | The Substrate Capture Mechanism of Mycobacterium tuberculosis Anthranilate Phosphoribosyltransferase Provides a Mode for Inhibition.
Biochemistry, 52, 2013
|
|
3RV9
 | | Structure of a M. tuberculosis Salicylate Synthase, MbtI, in Complex with an Inhibitor with Ethyl R-Group | | 分子名称: | 3-{[(1Z)-1-carboxybut-1-en-1-yl]oxy}-2-hydroxybenzoic acid, Isochorismate synthase/isochorismate-pyruvate lyase mbtI | | 著者 | Chi, G, Bulloch, E.M.M, Manos-Turvey, A, Payne, R.J, Lott, J.S, TB Structural Genomics Consortium (TBSGC) | | 登録日 | 2011-05-06 | | 公開日 | 2012-05-09 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | | 主引用文献 | Implications of binding mode and active site flexibility for inhibitor potency against the salicylate synthase from Mycobacterium tuberculosis
Biochemistry, 51, 2012
|
|
3RV8
 | | Structure of a M. tuberculosis Salicylate Synthase, MbtI, in Complex with an Inhibitor with Cyclopropyl R-Group | | 分子名称: | 3-{[(E)-1-carboxy-2-cyclopropylethenyl]oxy}-2-hydroxybenzoic acid, 3-{[(Z)-1-carboxy-2-cyclopropylethenyl]oxy}-2-hydroxybenzoic acid, Isochorismate synthase/isochorismate-pyruvate lyase mbtI | | 著者 | Chi, G, Bulloch, E.M.M, Manos-Turvey, A, Payne, R.J, Lott, J.S, TB Structural Genomics Consortium (TBSGC) | | 登録日 | 2011-05-06 | | 公開日 | 2012-05-09 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | | 主引用文献 | Implications of binding mode and active site flexibility for inhibitor potency against the salicylate synthase from Mycobacterium tuberculosis
Biochemistry, 51, 2012
|
|
3RV7
 | | Structure of a M. tuberculosis Salicylate Synthase, MbtI, in Complex with an Inhibitor with Isopropyl R-Group | | 分子名称: | 3-{[(1Z)-1-carboxy-3-methylbut-1-en-1-yl]oxy}-2-hydroxybenzoic acid, Isochorismate synthase/isochorismate-pyruvate lyase mbtI | | 著者 | Chi, G, Bulloch, E.M.M, Manos-Turvey, A, Payne, R.J, Lott, J.S, TB Structural Genomics Consortium (TBSGC) | | 登録日 | 2011-05-06 | | 公開日 | 2012-05-09 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Implications of binding mode and active site flexibility for inhibitor potency against the salicylate synthase from Mycobacterium tuberculosis
Biochemistry, 51, 2012
|
|
3RV6
 | | Structure of a M. tuberculosis Salicylate Synthase, MbtI, in Complex with an Inhibitor with Phenyl R-Group | | 分子名称: | 3-{[(E)-1-carboxy-2-phenylethenyl]oxy}-2-hydroxybenzoic acid, 3-{[(Z)-1-carboxy-2-phenylethenyl]oxy}-2-hydroxybenzoic acid, Isochorismate synthase/isochorismate-pyruvate lyase mbtI, ... | | 著者 | Chi, G, Bulloch, E.M.M, Manos-Turvey, A, Payne, R.J, Lott, J.S, TB Structural Genomics Consortium (TBSGC) | | 登録日 | 2011-05-06 | | 公開日 | 2012-05-09 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | | 主引用文献 | Implications of binding mode and active site flexibility for inhibitor potency against the salicylate synthase from Mycobacterium tuberculosis
Biochemistry, 51, 2012
|
|
3ST6
 | | Structure of a M. tuberculosis Synthase, MbtI, in Complex with an Isochorismate Analogue Inhibitor | | 分子名称: | 3-[(1-carboxyethenyl)oxy]-2-hydroxybenzoic acid, Isochorismate synthase/isochorismate-pyruvate lyase mbtI | | 著者 | Chi, G, Bulloch, E.M.M, Manos-Turvey, A, Payne, R.J, Lott, J.S, TB Structural Genomics Consortium (TBSGC) | | 登録日 | 2011-07-08 | | 公開日 | 2012-05-30 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Implications of binding mode and active site flexibility for inhibitor potency against the salicylate synthase from Mycobacterium tuberculosis
Biochemistry, 51, 2012
|
|
3TWP
 | | Crystal structure of M. tuberculosis TrpD in complex with an inhibitor | | 分子名称: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 2-HYDROXYBENZOIC ACID, Anthranilate phosphoribosyltransferase, ... | | 著者 | Castell, A, Short, F.L, Lott, J.S. | | 登録日 | 2011-09-22 | | 公開日 | 2012-09-26 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | The Substrate Capture Mechanism of Mycobacterium tuberculosis Anthranilate Phosphoribosyltransferase Provides a Mode for Inhibition.
Biochemistry, 52, 2013
|
|
1MBS
 | |
1E84
 | | Cytochrome c' from Alcaligenes xylosoxidans - reduced structure | | 分子名称: | CYTOCHROME C', HEME C | | 著者 | Lawson, D.M, Stevenson, C.E.M, Andrew, C.R, Eady, R.R. | | 登録日 | 2000-09-15 | | 公開日 | 2000-11-06 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Unprecedented Proximal Binding of Nitric Oxide to Heme: Implications for Guanylate Cyclase
Embo J., 19, 2000
|
|
1E86
 | | Cytochrome c' from Alcaligenes xylosoxidans - reduced structure with CO bound to distal side of heme | | 分子名称: | CARBON MONOXIDE, CYTOCHROME C', HEME C | | 著者 | Lawson, D.M, Stevenson, C.E.M, Andrew, C.R, Eady, R.R. | | 登録日 | 2000-09-15 | | 公開日 | 2000-11-06 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Unprecedented Proximal Binding of Nitric Oxide to Heme: Implications for Guanylate Cyclase
Embo J., 19, 2000
|
|
1E83
 | | Cytochrome c' from Alcaligenes xylosoxidans - oxidized structure | | 分子名称: | CYTOCHROME C', HEME C | | 著者 | Lawson, D.M, Stevenson, C.E.M, Andrew, C.R, Eady, R.R. | | 登録日 | 2000-09-15 | | 公開日 | 2000-11-06 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Unprecedented Proximal Binding of Nitric Oxide to Heme: Implications for Guanylate Cyclase
Embo J., 19, 2000
|
|
4N93
 | | Alternative substrates of Mycobacterium tuberculosis anthranilate phosphoribosyl transferase | | 分子名称: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 2-amino-6-methylbenzoic acid, Anthranilate phosphoribosyltransferase, ... | | 著者 | Castell, A, Short, F.L, Lott, J.S. | | 登録日 | 2013-10-19 | | 公開日 | 2014-04-23 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | Alternative substrates reveal catalytic cycle and key binding events in the reaction catalysed by anthranilate phosphoribosyltransferase from Mycobacterium tuberculosis.
Biochem.J., 461, 2014
|
|
4OWV
 | | Anthranilate phosphoribosyl transferase from Mycobacterium tuberculosis in complex with anthranilate | | 分子名称: | 2-AMINOBENZOIC ACID, Anthranilate phosphoribosyltransferase, GLYCEROL, ... | | 著者 | Castell, A, Cookson, T.V.M, Short, F.L, Lott, J.S. | | 登録日 | 2014-02-04 | | 公開日 | 2014-04-23 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Alternative substrates reveal catalytic cycle and key binding events in the reaction catalysed by anthranilate phosphoribosyltransferase from Mycobacterium tuberculosis.
Biochem.J., 461, 2014
|
|
4OWQ
 | | Anthranilate phosphoribosyl transferase from Mycobacterium tuberculosis in complex with 3-methylanthranilate, PRPP and Magnesium | | 分子名称: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 2-azanyl-3-methyl-benzoic acid, Anthranilate phosphoribosyltransferase, ... | | 著者 | Castell, A, Cookson, T.V.M, Short, F.L, Lott, J.S. | | 登録日 | 2014-02-03 | | 公開日 | 2014-04-23 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | | 主引用文献 | Alternative substrates reveal catalytic cycle and key binding events in the reaction catalysed by anthranilate phosphoribosyltransferase from Mycobacterium tuberculosis.
Biochem.J., 461, 2014
|
|
4OWM
 | | Anthranilate phosphoribosyl transferase from Mycobacterium tuberculosis in complex with 3-fluoroanthranilate, PRPP and Magnesium | | 分子名称: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 2-azanyl-3-fluoranyl-benzoic acid, Anthranilate phosphoribosyltransferase, ... | | 著者 | Castell, A, Cookson, T.V.M, Short, F.L, Lott, J.S. | | 登録日 | 2014-02-02 | | 公開日 | 2014-04-23 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Alternative substrates reveal catalytic cycle and key binding events in the reaction catalysed by anthranilate phosphoribosyltransferase from Mycobacterium tuberculosis.
Biochem.J., 461, 2014
|
|
4OWN
 | | Anthranilate phosphoribosyl transferase from Mycobacterium tuberculosis in complex with 5-fluoroanthranilate, PRPP and Magnesium | | 分子名称: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 2-amino-5-fluorobenzoic acid, Anthranilate phosphoribosyltransferase, ... | | 著者 | Castell, A, Cookson, T.V.M, Short, F.L, Lott, J.S. | | 登録日 | 2014-02-02 | | 公開日 | 2014-04-23 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | | 主引用文献 | Alternative substrates reveal catalytic cycle and key binding events in the reaction catalysed by anthranilate phosphoribosyltransferase from Mycobacterium tuberculosis.
Biochem.J., 461, 2014
|
|
4OWO
 | | Anthranilate phosphoribosyl transferase from Mycobacterium tuberculosis in complex with 6-fluoroanthranilate, PRPP and Magnesium | | 分子名称: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 2-azanyl-6-fluoranyl-benzoic acid, Anthranilate phosphoribosyltransferase, ... | | 著者 | Castell, A, Cookson, T.V.M, Short, F.L, Lott, J.S. | | 登録日 | 2014-02-02 | | 公開日 | 2014-04-23 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Alternative substrates reveal catalytic cycle and key binding events in the reaction catalysed by anthranilate phosphoribosyltransferase from Mycobacterium tuberculosis.
Biochem.J., 461, 2014
|
|
4OWU
 | | Anthranilate phosphoribosyl transferase from Mycobacterium tuberculosis in complex with 5-methylanthranilate, PRPP and Magnesium | | 分子名称: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 2-azanyl-5-methyl-benzoic acid, Anthranilate phosphoribosyltransferase, ... | | 著者 | Castell, A, Cookson, T.V.M, Short, F.L, Lott, J.S. | | 登録日 | 2014-02-03 | | 公開日 | 2014-04-23 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | | 主引用文献 | Alternative substrates reveal catalytic cycle and key binding events in the reaction catalysed by anthranilate phosphoribosyltransferase from Mycobacterium tuberculosis.
Biochem.J., 461, 2014
|
|
4OWS
 | | Anthranilate phosphoribosyl transferase from Mycobacterium tuberculosis in complex with 4-methylanthranilate, PRPP and Magnesium | | 分子名称: | 2-azanyl-4-methyl-benzoic acid, Anthranilate phosphoribosyltransferase, IMIDAZOLE, ... | | 著者 | Castell, A, Cookson, T.V.M, Short, F.L, Lott, J.S. | | 登録日 | 2014-02-03 | | 公開日 | 2014-04-23 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | | 主引用文献 | Alternative substrates reveal catalytic cycle and key binding events in the reaction catalysed by anthranilate phosphoribosyltransferase from Mycobacterium tuberculosis.
Biochem.J., 461, 2014
|
|
2INS
 | | THE STRUCTURE OF DES-PHE B1 BOVINE INSULIN | | 分子名称: | DES-PHE B1 INSULIN (CHAIN A), DES-PHE B1 INSULIN (CHAIN B), ZINC ION | | 著者 | Smith, G.D, Duax, W.L, Dodson, E.J, Dodson, G.G, Degraaf, R.A.G, Reynolds, C.D. | | 登録日 | 1982-05-10 | | 公開日 | 1982-08-05 | | 最終更新日 | 2017-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The Structure of Des-Phe B1 Bovine Insulin
Acta Crystallogr.,Sect.B, 38, 1982
|
|
2JB7
 | | PAE2307 with AMP | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETATE ION, ADENOSINE MONOPHOSPHATE, ... | | 著者 | Rajasekaran, K, Lott, J.S, Johnston, J.M. | | 登録日 | 2006-12-04 | | 公開日 | 2008-08-05 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Pae2307 a Phosphotransferase
To be Published
|
|
1BEN
 | | INSULIN COMPLEXED WITH 4-HYDROXYBENZAMIDE | | 分子名称: | 4-HYDROXYBENZAMIDE, CHLORIDE ION, HUMAN INSULIN, ... | | 著者 | Smith, G.D, Ciszak, E, Pangborn, W. | | 登録日 | 1996-02-15 | | 公開日 | 1996-07-11 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | A novel complex of a phenolic derivative with insulin: structural features related to the T-->R transition.
Protein Sci., 5, 1996
|
|
5ID2
 | |
2BJJ
 | | Structure of recombinant human lactoferrin produced in the milk of transgenic cows | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, FE (III) ION, ... | | 著者 | Thomassen, E.A.J, Van Veen, H.A, Van Berkel, P.H.C, Nuijens, J.H, Abrahams, J.P. | | 登録日 | 2005-02-03 | | 公開日 | 2005-08-01 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | The Protein Structure of Recombinant Human Lactoferrin Produced in the Milk of Transgenic Cows Closely Matches the Structure of Human Milk-Derived Lactoferrin
Transgenic Res., 14, 2005
|
|
3BXD
 | | Crystal structure of Mouse Myo-inositol oxygenase (re-refined) | | 分子名称: | 1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE, FE (III) ION, FORMIC ACID, ... | | 著者 | Hallberg, B.M. | | 登録日 | 2008-01-13 | | 公開日 | 2008-02-05 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural and biophysical characterization of human myo-inositol oxygenase.
J.Biol.Chem., 283, 2008
|
|
