4KHT
| Triple helix bundle of GP41 complexed with fab 8066 | Descriptor: | 8066 heavy chain, 8066 light chain, Gp41 helix | Authors: | Li, M, Gustchina, A, Wlodawer, A. | Deposit date: | 2013-05-01 | Release date: | 2014-03-12 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (2.817 Å) | Cite: | Complexes of neutralizing and non-neutralizing affinity matured Fabs with a mimetic of the internal trimeric coiled-coil of HIV-1 gp41. Plos One, 8, 2013
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4KHX
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7AWT
| E. coli NADH quinone oxidoreductase hydrophilic arm | Descriptor: | FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, IRON/SULFUR CLUSTER, ... | Authors: | Schimpf, J, Grishkovskaya, I, Haselbach, D, Friedrich, T. | Deposit date: | 2020-11-09 | Release date: | 2021-09-15 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.73 Å) | Cite: | Structure of the peripheral arm of a minimalistic respiratory complex I. Structure, 30, 2022
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1S1A
| Pterocarpus angolensis seed lectin (PAL) with one binding site free and one binding site containing the disaccharide Man(a1-3)ManMe | Descriptor: | CALCIUM ION, Lectin, MANGANESE (II) ION, ... | Authors: | Buts, L, Imberty, A, Wyns, L, Beeckmans, S, Loris, R. | Deposit date: | 2004-01-06 | Release date: | 2005-01-18 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: |
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7Q9B
| MHC Class I A02 Allele presenting EAAGIGILTV, in complex with Mel8 TCR | Descriptor: | 1,2-ETHANEDIOL, Beta-2-microglobulin, GLU-ALA-ALA-GLY-ILE-GLY-ILE-LEU-THR-VAL, ... | Authors: | Rizkallah, P.J, Sewell, A.K, Wall, A, Fuller, A. | Deposit date: | 2021-11-12 | Release date: | 2023-02-22 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3.24 Å) | Cite: | Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy. Cell, 186, 2023
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7Q99
| MHC Class I A02 Allele presenting NLSALGIFST, in complex with Mel5 TCR | Descriptor: | 1,2-ETHANEDIOL, ASN-LEU-SER-ALA-LEU-GLY-ILE-PHE-SER-THR, Beta-2-microglobulin, ... | Authors: | Rizkallah, P.J, Sewell, A.K, Wall, A, Fuller, A. | Deposit date: | 2021-11-12 | Release date: | 2023-02-22 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy. Cell, 186, 2023
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7Q98
| MHC Class I A02 Allele presenting NLSALGIFST | Descriptor: | 1,2-ETHANEDIOL, ASN-LEU-SER-ALA-LEU-GLY-ILE-PHE-SER-THR, Beta-2-microglobulin, ... | Authors: | Rizkallah, P.J, Sewell, A.K. | Deposit date: | 2021-11-12 | Release date: | 2023-02-22 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy. Cell, 186, 2023
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7Q9A
| MHC Class I A02 Allele presenting LLLGIGILVL, in complex with Mel5 TCR | Descriptor: | Beta-2-microglobulin, GLYCEROL, Human Mel5 T Cell Receptor, ... | Authors: | Rizkallah, P.J, Sewell, A.K, Wall, A, Fuller, A. | Deposit date: | 2021-11-12 | Release date: | 2023-02-22 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy. Cell, 186, 2023
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7ANT
| Structure of CYP153A from Polaromonas sp. | Descriptor: | 1,2-ETHANEDIOL, Cytochrome P450, HEME C | Authors: | Zukic, E, Rowlinson, B, Sharma, M, Hoffman, S, Hauer, B, Grogan, G. | Deposit date: | 2020-10-12 | Release date: | 2021-04-07 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | Substrate Anchoring and Flexibility Reduction in CYP153AM.aq Leads to Highly Improved Efficiency toward Octanoic Acid Acs Catalysis, 11, 2021
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7AO7
| Structure of CYP153A from Polaromonas sp. in complex with octan-1-ol | Descriptor: | Cytochrome P450, OCTAN-1-OL, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Zukic, E, Rowlinson, B, Sharma, M, Hoffmann, S, Hauer, B, Grogan, G. | Deposit date: | 2020-10-13 | Release date: | 2021-04-07 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Substrate Anchoring and Flexibility Reduction in CYP153AM.aq Leads to Highly Improved Efficiency toward Octanoic Acid Acs Catalysis, 11, 2021
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6Y5V
| Structure of Human Potassium Chloride Transporter KCC3b (S45D/T940D/T997D) in KCl | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Solute carrier family 12 member 6, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Chi, G, Man, H, Ebenhoch, R, Reggiano, G, Pike, A.C.W, Wang, D, McKinley, G, Mukhopadhyay, S.M.M, MacLean, E.M, Chalk, R, Moreau, C, Snee, M, Bohstedt, T, Singh, N.K, Abrusci, P, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Marsden, B.D, Burgess-Brown, N.A, DiMaio, F, Duerr, K.L. | Deposit date: | 2020-02-25 | Release date: | 2020-07-15 | Last modified: | 2024-10-16 | Method: | ELECTRON MICROSCOPY (4.08 Å) | Cite: | Phospho-regulation, nucleotide binding and ion access control in potassium-chloride cotransporters. Embo J., 40, 2021
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4USE
| Human STK10 (LOK) with SB-633825 | Descriptor: | 4-{5-(6-methoxynaphthalen-2-yl)-1-methyl-2-[2-methyl-4-(methylsulfonyl)phenyl]-1H-imidazol-4-yl}pyridine, SERINE/THREONINE-PROTEIN KINASE 10 | Authors: | Elkins, J.M, Salah, E, Szklarz, M, von Delft, F, Canning, P, Raynor, J, Bountra, C, Edwards, A.M, Knapp, S. | Deposit date: | 2014-07-07 | Release date: | 2015-07-22 | Last modified: | 2018-01-24 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Comprehensive Characterization of the Published Kinase Inhibitor Set. Nat.Biotechnol., 34, 2016
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9FCZ
| Coxsackievirus A9 bound with compound 17 (CL301) | Descriptor: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | Authors: | Plavec, Z, Butcher, S.J, Mitchell, C, Buckner, C. | Deposit date: | 2024-05-16 | Release date: | 2024-10-02 | Method: | ELECTRON MICROSCOPY (2.53 Å) | Cite: | SAR Analysis of Novel Coxsackie virus A9 Capsid Binders. J.Med.Chem., 2024
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9FO2
| Coxsackievirus A9 bound with compound 15 (CL278) | Descriptor: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | Authors: | Plavec, Z, Butcher, S.J, Mitchell, C, Buckner, C. | Deposit date: | 2024-06-11 | Release date: | 2024-10-02 | Method: | ELECTRON MICROSCOPY (2.58 Å) | Cite: | SAR Analysis of Novel Coxsackie virus A9 Capsid Binders. J.Med.Chem., 2024
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9FO5
| Coxsackievirus A9 bound with compound 19 (CL313) | Descriptor: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | Authors: | Plavec, Z, Butcher, S.J, Mitchell, C, Buckner, C. | Deposit date: | 2024-06-11 | Release date: | 2024-10-02 | Method: | ELECTRON MICROSCOPY (2.69 Å) | Cite: | SAR Analysis of Novel Coxsackie virus A9 Capsid Binders. J.Med.Chem., 2024
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9FGN
| Coxsackievirus A9 bound with compound 18 (CL304) | Descriptor: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | Authors: | Plavec, Z, Butcher, S.J, Mitchell, C, Buckner, C. | Deposit date: | 2024-05-24 | Release date: | 2024-10-02 | Method: | ELECTRON MICROSCOPY (2.64 Å) | Cite: | SAR Analysis of Novel Coxsackie virus A9 Capsid Binders. J.Med.Chem., 2024
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9EXI
| Coxsackievirus A9 bound with compound 14 (CL275) | Descriptor: | 4-[(4-methylpiperazin-1-yl)methyl]-N-[[4-(trifluoromethyl)phenyl]methyl]aniline, Capsid protein VP1, Capsid protein VP2, ... | Authors: | Plavec, Z, Butcher, S.J, Mitchell, C, Buckner, C. | Deposit date: | 2024-04-08 | Release date: | 2024-10-02 | Method: | ELECTRON MICROSCOPY (2.31 Å) | Cite: | SAR Analysis of Novel Coxsackie virus A9 Capsid Binders. J.Med.Chem., 2024
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9FP5
| Coxsackievirus A9 bound with CL213. | Descriptor: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | Authors: | Plavec, Z, Butcher, S.J, Mitchell, C, Buckner, C. | Deposit date: | 2024-06-13 | Release date: | 2024-10-02 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | SAR Analysis of Novel Coxsackie virus A9 Capsid Binders. J.Med.Chem., 2024
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9FA9
| Coxsackievirus A9 bound with compound 16 (CL298) | Descriptor: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | Authors: | Plavec, Z, Butcher, S.J, Mitchell, C, Buckner, C. | Deposit date: | 2024-05-10 | Release date: | 2024-10-02 | Method: | ELECTRON MICROSCOPY (2.75 Å) | Cite: | SAR Analysis of Novel Coxsackie virus A9 Capsid Binders. J.Med.Chem., 2024
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7S83
| Crystal structure of SARS CoV-2 Spike Receptor Binding Domain in complex with shark neutralizing VNARs ShAb01 and ShAb02 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ShAb01 VNAR, ... | Authors: | Chen, W.-H, Hajduczki, A, Dooley, H.M, Joyce, M.G. | Deposit date: | 2021-09-17 | Release date: | 2022-11-23 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.52 Å) | Cite: | Shark nanobodies with potent SARS-CoV-2 neutralizing activity and broad sarbecovirus reactivity. Nat Commun, 14, 2023
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9FKZ
| Discovery of a Series of Covalent, Cell Active Bfl-1 Inhibitors | Descriptor: | Bcl-2-related protein A1, ~{N}-[4-[(1~{R},3~{R})-3-azanylcyclopentyl]oxyphenyl]-~{N}-[(4-chlorophenyl)methyl]prop-2-enamide | Authors: | Hargreaves, D. | Deposit date: | 2024-06-04 | Release date: | 2024-10-02 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (1.684 Å) | Cite: | Structure-Based Optimization of a Series of Covalent, Cell Active Bfl-1 Inhibitors. J.Med.Chem., 67, 2024
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9FL0
| Discovery of a Series of Covalent, Cell Active Bfl-1 Inhibitors | Descriptor: | Bcl-2-related protein A1, ~{N}-[(4-chlorophenyl)methyl]-~{N}-(4-fluorophenyl)prop-2-enamide | Authors: | Hargreaves, D. | Deposit date: | 2024-06-04 | Release date: | 2024-10-02 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Structure-Based Optimization of a Series of Covalent, Cell Active Bfl-1 Inhibitors. J.Med.Chem., 67, 2024
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9FKY
| Discovery of a Series of Covalent, Cell Active Bfl-1 Inhibitors | Descriptor: | Bcl-2-related protein A1, ~{N}-[4-[(1~{R},3~{R})-3-azanylcyclopentyl]oxyphenyl]-~{N}-[(1~{S})-1-[3-cyano-4-(trifluoromethyl)phenyl]ethyl]propanamide | Authors: | Hargreaves, D. | Deposit date: | 2024-06-04 | Release date: | 2024-10-02 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (1.557 Å) | Cite: | Structure-Based Optimization of a Series of Covalent, Cell Active Bfl-1 Inhibitors. J.Med.Chem., 67, 2024
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1CKN
| STRUCTURE OF GUANYLYLATED MRNA CAPPING ENZYME COMPLEXED WITH GTP | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, MRNA CAPPING ENZYME, ... | Authors: | Hakansson, K, Doherty, A.J, Wigley, D.B. | Deposit date: | 1997-04-20 | Release date: | 1997-07-07 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | X-ray crystallography reveals a large conformational change during guanyl transfer by mRNA capping enzymes. Cell(Cambridge,Mass.), 89, 1997
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1CKM
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