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1NZK
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BU of 1nzk by Molmil
Crystal Structure of a Multiple Mutant (L44F, L73V, V109L, L111I, C117V) of Human Acidic Fibroblast Growth Factor
Descriptor: Acidic Fibroblast Growth Factor, FORMIC ACID, SULFATE ION
Authors:Brych, S.R, Kim, J, Logan, T.M, Blaber, M.
Deposit date:2003-02-18
Release date:2004-03-02
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Accommodation of a highly symmetric core within a symmetric protein superfold.
Protein Sci., 12, 2003
1Q03
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BU of 1q03 by Molmil
Crystal structure of FGF-1, S50G/V51G mutant
Descriptor: Heparin-binding growth factor 1
Authors:Kim, J, Blaber, M.
Deposit date:2003-07-15
Release date:2004-07-27
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Sequence swapping does not result in conformation swapping for the beta4/beta5 and beta8/beta9 beta-hairpin turns in human acidic fibroblast growth factor
Protein Sci., 14, 2005
1P63
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BU of 1p63 by Molmil
Human Acidic Fibroblast Growth Factor. 140 Amino Acid Form with Amino Terminal His Tag and Leu111 Replaced with Ile (L111I)
Descriptor: ACIDIC FIBROBLAST GROWTH FACTOR, FORMIC ACID, SULFATE ION
Authors:Brych, S.R, Kim, J, Logan, T.M, Blaber, M.
Deposit date:2003-04-28
Release date:2004-05-11
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Accommodation of a highly symmetric core within a symmetric protein superfold
Protein Sci., 12, 2003
1RG8
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BU of 1rg8 by Molmil
Human Acidic Fibroblast Growth Factor (haFGF-1) at 1.10 angstrom resolution (140 amino acid form)
Descriptor: FORMIC ACID, Heparin-binding growth factor 1
Authors:Bernett, M.J, Somasundaram, T, Blaber, M.
Deposit date:2003-11-11
Release date:2004-10-05
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:An atomic resolution structure for human fibroblast growth factor 1.
Proteins, 57, 2004
1M9H
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BU of 1m9h by Molmil
Corynebacterium 2,5-DKGR A and Phe 22 replaced with Tyr (F22Y), Lys 232 replaced with Gly (K232G), Arg 238 replaced with His (R238H)and Ala 272 replaced with Gly (A272G)in presence of NADH cofactor
Descriptor: 2,5-diketo-D-gluconic acid reductase A, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION
Authors:Sanli, G, Blaber, M.
Deposit date:2002-07-29
Release date:2003-08-12
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural alteration of cofactor specificity in Corynebacterium 2,5-diketo-D-gluconic acid reductase
Protein Sci., 13, 2004
1JY0
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BU of 1jy0 by Molmil
Human acidic fibroblast growth factor. 141 amino acid form with amino terminal His tag and Cys 117 replaced with Val (C117V).
Descriptor: FORMIC ACID, acidic fibroblast growth factor
Authors:Brych, S.R, Blaber, M.
Deposit date:2001-09-10
Release date:2003-08-12
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Accommodation of a highly symmetric core within a symmetric protein superfold.
Protein Sci., 12, 2003
1M16
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BU of 1m16 by Molmil
Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag and Leu 44 Replaced with Phe (L44F), Leu 73 Replaced with Val (L73V), Val 109 Replaced with Leu (V109L) and Cys 117 Replaced with Val (C117V).
Descriptor: FORMIC ACID, SULFATE ION, acidic fibroblast growth factor
Authors:Brych, S.R, Kim, J, Spielmann, G.L, Logan, T.M, Blaber, M.
Deposit date:2002-06-17
Release date:2003-08-05
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Accommodation of a highly symmetric core within a symmetric protein superfold
Protein Sci., 12, 2003
3VTE
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BU of 3vte by Molmil
Crystal structure of tetrahydrocannabinolic acid synthase from Cannabis sativa
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, FLAVIN-ADENINE DINUCLEOTIDE, Tetrahydrocannabinolic acid synthase
Authors:Shoyama, Y, Tamada, T, Kurihara, K, Takeuchi, A, Taura, F, Arai, S, Blaber, M, Shoyama, Y, Morimoto, S, Kuroki, R.
Deposit date:2012-05-28
Release date:2012-07-25
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structure and function of 1-tetrahydrocannabinolic acid (THCA) synthase, the enzyme controlling the psychoactivity of Cannabis sativa
J.Mol.Biol., 423, 2012
4QKR
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BU of 4qkr by Molmil
Crystal Structure of 6xTyr/PV2: de novo designed beta-trefoil architecture with symmetric primary structure (L22Y/L44Y/L64Y/L85Y/L108Y/L132Y, Primitive Version 2)
Descriptor: DE NOVO PROTEIN 6XTYR/PV2, IMIDAZOLE
Authors:Longo, L.M, Blaber, M, Tenorio, C.A.
Deposit date:2014-06-09
Release date:2015-01-14
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.746 Å)
Cite:A single aromatic core mutation converts a designed "primitive" protein from halophile to mesophile folding.
Protein Sci., 24, 2015
4QKS
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BU of 4qks by Molmil
Crystal Structure of 6xTrp/PV2: de novo designed beta-trefoil architecture with symmetric primary structure (L22W/L44W/L64W/L85W/L108W/L132W his Primitive Version 2)
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DE NOVO PROTEIN 6XTRP/PV2, SULFATE ION
Authors:Longo, L.M, Tenorio, C.A, Blaber, M.
Deposit date:2014-06-09
Release date:2015-01-14
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A single aromatic core mutation converts a designed "primitive" protein from halophile to mesophile folding.
Protein Sci., 24, 2015
4Q91
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BU of 4q91 by Molmil
Crystal structure of C16A/K12V/C117V/P134V mutant of human acidic fibroblast growth factor
Descriptor: FORMIC ACID, Fibroblast growth factor 1, PHOSPHATE ION
Authors:Xia, X, Blaber, M.
Deposit date:2014-04-28
Release date:2015-03-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.799 Å)
Cite:Mutation choice to eliminate buried free cysteines in protein therapeutics.
J.Pharm.Sci., 104, 2015
3O4B
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BU of 3o4b by Molmil
Crystal structure of Symfoil-4T: de novo designed beta-trefoil architecture with symmetric primary structure
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, SULFATE ION, ...
Authors:Lee, J, Blaber, M.
Deposit date:2010-07-26
Release date:2010-12-22
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Experimental support for the evolution of symmetric protein architecture from a simple peptide motif.
Proc.Natl.Acad.Sci.USA, 108, 2011
3O4A
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BU of 3o4a by Molmil
Crystal structure of Symfoil-2: de novo designed beta-trefoil architecture with symmetric primary structure
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, SULFATE ION, de novo designed beta-trefoil architecture with symmetric primary structure
Authors:Lee, J, Blaber, M.
Deposit date:2010-07-26
Release date:2010-12-22
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Experimental support for the evolution of symmetric protein architecture from a simple peptide motif.
Proc.Natl.Acad.Sci.USA, 108, 2011
3OL0
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BU of 3ol0 by Molmil
Crystal structure of Monofoil-4P homo-trimer: de novo designed monomer trefoil-fold sub-domain which forms homo-trimer assembly
Descriptor: SULFATE ION, de novo designed monomer trefoil-fold sub-domain which forms homo-trimer assembly
Authors:Lee, J, Blaber, M.
Deposit date:2010-08-25
Release date:2010-12-22
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.483 Å)
Cite:Experimental support for the evolution of symmetric protein architecture from a simple peptide motif.
Proc.Natl.Acad.Sci.USA, 108, 2011
3O49
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BU of 3o49 by Molmil
Crystal structure of Symfoil-1: de novo designed beta-trefoil architecture with symmetric primary structure
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, SULFATE ION, de novo designed beta-trefoil architecture with symmetric primary structure
Authors:Lee, J, Blaber, M.
Deposit date:2010-07-26
Release date:2010-12-22
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Experimental support for the evolution of symmetric protein architecture from a simple peptide motif.
Proc.Natl.Acad.Sci.USA, 108, 2011
3O4C
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BU of 3o4c by Molmil
Crystal structure of Symfoil-4V: de novo designed beta-trefoil architecture with symmetric primary structure
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, SULFATE ION, ...
Authors:Lee, J, Blaber, M.
Deposit date:2010-07-26
Release date:2010-12-22
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Experimental support for the evolution of symmetric protein architecture from a simple peptide motif.
Proc.Natl.Acad.Sci.USA, 108, 2011
3OGF
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BU of 3ogf by Molmil
Crystal structure of Difoil-4P homo-trimer: de novo designed dimeric trefoil-fold sub-domain which forms homo-trimer assembly
Descriptor: SULFATE ION, de novo designed dimeric trefoil-fold sub-domain which forms homo-trimer assembly
Authors:Lee, J, Blaber, M.
Deposit date:2010-08-16
Release date:2010-12-22
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.864 Å)
Cite:Experimental support for the evolution of symmetric protein architecture from a simple peptide motif.
Proc.Natl.Acad.Sci.USA, 108, 2011
3O4D
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BU of 3o4d by Molmil
Crystal structure of Symfoil-4P: de novo designed beta-trefoil architecture with symmetric primary structure
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, SULFATE ION, ...
Authors:Lee, J, Blaber, M.
Deposit date:2010-07-26
Release date:2010-12-22
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Experimental support for the evolution of symmetric protein architecture from a simple peptide motif.
Proc.Natl.Acad.Sci.USA, 108, 2011
3BAG
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BU of 3bag by Molmil
Crystal structure of K112N/N114A mutant of Human acidic fibroblast growth factor
Descriptor: FORMIC ACID, Heparin-binding growth factor 1
Authors:Lee, J, Blaber, M.
Deposit date:2007-11-07
Release date:2008-04-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:A logical OR redundancy within the Asx-Pro-Asx-Gly type I beta-turn motif.
J.Mol.Biol., 377, 2008
3BAU
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BU of 3bau by Molmil
Crystal structure of K12V/L26D/D28A mutant of Human acidic fibroblast growth factor
Descriptor: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION
Authors:Lee, J, Blaber, M.
Deposit date:2007-11-08
Release date:2008-04-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:A logical OR redundancy within the Asx-Pro-Asx-Gly type I beta-turn motif.
J.Mol.Biol., 377, 2008
3BAQ
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BU of 3baq by Molmil
Crystal structure of L26A mutant of Human acidic fibroblast growth factor
Descriptor: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION
Authors:Lee, J, Blaber, M.
Deposit date:2007-11-08
Release date:2008-04-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A logical OR redundancy within the Asx-Pro-Asx-Gly type I beta-turn motif.
J.Mol.Biol., 377, 2008
3BAH
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BU of 3bah by Molmil
Crystal structure of K112N mutant of Human acidic fibroblast growth factor
Descriptor: FORMIC ACID, Heparin-binding growth factor 1
Authors:Lee, J, Blaber, M.
Deposit date:2007-11-07
Release date:2008-04-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:A logical OR redundancy within the Asx-Pro-Asx-Gly type I beta-turn motif.
J.Mol.Biol., 377, 2008
3BAO
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BU of 3bao by Molmil
Crystal structure of L26N mutant of Human acidic fibroblast growth factor
Descriptor: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION
Authors:Lee, J, Blaber, M.
Deposit date:2007-11-08
Release date:2008-04-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:A logical OR redundancy within the Asx-Pro-Asx-Gly type I beta-turn motif.
J.Mol.Biol., 377, 2008
3BAV
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BU of 3bav by Molmil
Crystal structure of L26A/D28N mutant of Human acidic fibroblast growth factor
Descriptor: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION
Authors:Lee, J, Blaber, M.
Deposit date:2007-11-08
Release date:2008-04-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:A logical OR redundancy within the Asx-Pro-Asx-Gly type I beta-turn motif.
J.Mol.Biol., 377, 2008
3BB2
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BU of 3bb2 by Molmil
Crystal structure of L26D/D28N mutant of Human acidic fibroblast growth factor
Descriptor: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION
Authors:Lee, J, Blaber, M.
Deposit date:2007-11-09
Release date:2008-04-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:A logical OR redundancy within the Asx-Pro-Asx-Gly type I beta-turn motif.
J.Mol.Biol., 377, 2008

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