6CXD
 
 | | Crystal structure of peptidase B from Yersinia pestis CO92 at 2.75 A resolution | | Descriptor: | Peptidase B, SULFATE ION | | Authors: | Woinska, M, Lipowska, J, Shabalin, I.G, Cymborowski, M, Grimshaw, S, Winsor, J, Shuvalova, L, Satchell, K.J, Joachimiak, A, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2018-04-02 | | Release date: | 2018-04-18 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | Structural and biochemical analysis of Bacillus anthracis prephenate dehydrogenase reveals an unusual mode of inhibition by tyrosine via the ACT domain.
Febs J., 287, 2020
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4D4Y
 | | Focal Adhesion Kinase catalytic domain | | Descriptor: | DIMETHYL SULFOXIDE, FOCAL ADHESION KINASE 1, SULFATE ION | | Authors: | Le Coq, J, Lin, A, Lietha, D. | | Deposit date: | 2014-10-31 | | Release date: | 2015-02-18 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Allosteric Regulation of Focal Adhesion Kinase by Pip2 and ATP.
Biophys.J., 108, 2015
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3EUP
 | | The crystal structure of the transcriptional regulator, TetR family from Cytophaga hutchinsonii | | Descriptor: | SULFATE ION, Transcriptional regulator, TetR family | | Authors: | Zhang, R, Bigelow, L, Abdullah, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2008-10-10 | | Release date: | 2008-11-25 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.99 Å) | | Cite: | The crystal structure of the transcriptional regulator, TetR family from Cytophaga hutchinsonii
To be Published
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4D55
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4UUZ
 | | MCM2-histone complex | | Descriptor: | DNA REPLICATION LICENSING FACTOR MCM2, HISTONE H3, HISTONE H4 | | Authors: | Richet, N, Liu, D, Legrand, P, Bakail, M, Compper, C, Besle, A, Guerois, R, Ochsenbein, F. | | Deposit date: | 2014-08-01 | | Release date: | 2015-02-11 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structural Insight Into How the Human Helicase Subunit Mcm2 May Act as a Histone Chaperone Together with Asf1 at the Replication Fork.
Nucleic Acids Res., 43, 2015
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3EWL
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3EWI
 | | Structural analysis of the C-terminal domain of murine CMP-Sialic acid Synthetase | | Descriptor: | N-acylneuraminate cytidylyltransferase | | Authors: | Oschlies, M, Dickmanns, A, Stummeyer, K, Gerardy-Schahn, R, Ficner, R, Muenster-Kuehnel, A.K. | | Deposit date: | 2008-10-15 | | Release date: | 2009-08-18 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | A C-terminal phosphatase module conserved in vertebrate CMP-sialic acid synthetases provides a tetramerization interface for the physiologically active enzyme.
J.Mol.Biol., 393, 2009
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4UU4
 | | Crystal structure of LptH, the LptA homologous periplasmic component of the conserved lipopolysaccharide transport device from Pseudomonas aeruginosa | | Descriptor: | PERIPLASMIC LIPOPOLYSACCHARIDE TRANSPORT PROTEIN LPTH | | Authors: | Bollati, M, Villa, R, Gourlay, L.J, Barbiroli, A, Deho, G, Benedet, M, Polissi, A, Martorana, A, Sperandeo, P, Bolognesi, M, Nardini, M. | | Deposit date: | 2014-07-24 | | Release date: | 2015-03-25 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.751 Å) | | Cite: | Crystal Structure of Lpth, the Periplasmic Component of the Lipopolysaccharide Transport Machinery from Pseudomonas Aeruginosa.
FEBS J., 282, 2015
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1KXT
 | | Camelid VHH Domains in Complex with Porcine Pancreatic alpha-Amylase | | Descriptor: | ALPHA-AMYLASE, PANCREATIC, CALCIUM ION, ... | | Authors: | Desmyter, A, Spinelli, S, Payan, F, Lauwereys, M, Wyns, L, Muyldermans, S, Cambillau, C. | | Deposit date: | 2002-02-01 | | Release date: | 2002-06-19 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Three camelid VHH domains in complex with porcine pancreatic alpha-amylase. Inhibition and versatility of binding topology.
J.Biol.Chem., 277, 2002
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3EW2
 | | Crystal structure of rhizavidin-biotin complex | | Descriptor: | BIOTIN, rhizavidin | | Authors: | Livnah, O, Meir, A. | | Deposit date: | 2008-10-14 | | Release date: | 2008-12-23 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure of rhizavidin: insights into the enigmatic high-affinity interaction of an innate biotin-binding protein dimer.
J.Mol.Biol., 386, 2009
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3EY5
 | | Putative acetyltransferase from GNAT family from Bacteroides thetaiotaomicron. | | Descriptor: | Acetyltransferase-like, GNAT family, SULFATE ION | | Authors: | Osipiuk, J, Bigelow, L, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2008-10-17 | | Release date: | 2008-11-18 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | X-ray crystal structure of putative acetyltransferase from GNAT family from Bacteroides thetaiotaomicron.
To be Published
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3F0A
 | | Structure of a putative n-acetyltransferase (ta0374) in complex with acetyl-coa from thermoplasma acidophilum | | Descriptor: | ACETYL COENZYME *A, CHLORIDE ION, N-ACETYLTRANSFERASE, ... | | Authors: | Filippova, E.V, Minasov, G, Shuvalova, L, Kiryukhina, O, Clancy, S, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2008-10-24 | | Release date: | 2008-11-11 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structure of the novel PaiA N-acetyltransferase from Thermoplasma acidophilum involved in the negative control of sporulation and degradative enzyme production.
Proteins, 79, 2011
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1KEF
 | | PDZ1 of SAP90 | | Descriptor: | synapse associated protein-90 | | Authors: | Piserchio, A, Pellegrini, M, Mehta, S, Blackman, S.M, Garcia, E.P, Marshall, J, Mierke, D.F. | | Deposit date: | 2001-11-15 | | Release date: | 2002-03-06 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | The PDZ1 domain of SAP90. Characterization of structure and binding.
J.Biol.Chem., 277, 2002
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3F3A
 | | Crystal Structure of LeuT bound to L-Tryptophan and Sodium | | Descriptor: | SODIUM ION, TETRADECANE, TRYPTOPHAN, ... | | Authors: | Singh, S.K, Piscitelli, C.L, Yamashita, A, Gouaux, E. | | Deposit date: | 2008-10-30 | | Release date: | 2008-12-23 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | A competitive inhibitor traps LeuT in an open-to-out conformation.
Science, 322, 2008
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4D09
 | | PDE2a catalytic domain in complex with a brain penetrant inhibitor | | Descriptor: | CGMP-DEPENDENT 3', 5'-CYCLIC PHOSPHODIESTERASE, MAGNESIUM ION, ... | | Authors: | Buijnsters, P, Andres, J.I, DeAngelis, M, Langlois, X, Rombouts, F, Sanderson, W, Tresadern, G, Trabanco, A, VanHoof, G, VanRoosbroeck, Y. | | Deposit date: | 2014-04-24 | | Release date: | 2014-08-06 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structure-Based Design of a Potent, Selective, and Brain Penetrating Pde2 Inhibitor with Demonstrated Target Engagement.
Acs Med.Chem.Lett., 5, 2014
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3F3P
 | | Crystal structure of the nucleoporin pair Nup85-Seh1, space group P21212 | | Descriptor: | Nucleoporin NUP85, Nucleoporin SEH1 | | Authors: | Debler, E.W, Hseo, H, Ma, Y, Blobel, G, Hoelz, A. | | Deposit date: | 2008-10-31 | | Release date: | 2009-04-07 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | A fence-like coat for the nuclear pore membrane.
Mol.Cell, 32, 2008
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1KEX
 | | Crystal Structure of the b1 Domain of Human Neuropilin-1 | | Descriptor: | Neuropilin-1 | | Authors: | Lee, C.C, Kreusch, A, McMullan, D, Ng, K, Spraggon, G. | | Deposit date: | 2001-11-18 | | Release date: | 2003-01-28 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal Structure of the Human Neuropilin-1 b1 Domain
Structure, 11, 2003
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3FBM
 | | D431N Mutant VP2 Protein of Infectious Bursal Disease Virus; Derived T=1 Particles | | Descriptor: | CALCIUM ION, Polyprotein | | Authors: | Irigoyen, N, Garriga, D, Navarro, A, Verdaguer, N, Rodriguez, J.F, Caston, J.R. | | Deposit date: | 2008-11-19 | | Release date: | 2009-01-13 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Autoproteolytic Activity Derived from the Infectious Bursal Disease Virus Capsid Protein
J.Biol.Chem., 284, 2009
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6D3W
 | | Chromosomal trehalose-6-phosphate phosphatase from P. aeruginosa | | Descriptor: | 1,2-ETHANEDIOL, ACETIC ACID, CALCIUM ION, ... | | Authors: | Hofmann, A, Cross, M, Park, S.-Y. | | Deposit date: | 2018-04-17 | | Release date: | 2018-05-09 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Trehalose 6-phosphate phosphatases of Pseudomonas aeruginosa.
FASEB J., 32, 2018
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1KOG
 | | Crystal structure of E. coli threonyl-tRNA synthetase interacting with the essential domain of its mRNA operator | | Descriptor: | 5'-O-(N-(L-THREONYL)-SULFAMOYL)ADENOSINE, Threonyl-tRNA synthetase, Threonyl-tRNA synthetase mRNA, ... | | Authors: | Torres-Larrios, A, Dock-Bregeon, A.C, Romby, P, Rees, B, Sankaranarayanan, R, Caillet, J, Springer, M, Ehresmann, C, Ehresmann, B, Moras, D. | | Deposit date: | 2001-12-20 | | Release date: | 2002-04-26 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Structural basis of translational control by Escherichia coli threonyl tRNA synthetase.
Nat.Struct.Biol., 9, 2002
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1KL4
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3F2K
 | | Structure of the transposase domain of human Histone-lysine N-methyltransferase SETMAR | | Descriptor: | Histone-lysine N-methyltransferase SETMAR, LYFA Peptide, MAGNESIUM ION | | Authors: | Amaya, M.F, Dombrovski, L, Ni, S, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Botchkarev, A, Min, J, Plotnikov, A.N, Wu, H, Structural Genomics Consortium (SGC) | | Deposit date: | 2008-10-29 | | Release date: | 2008-11-25 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | The Crystal Structure of Transposase Domain of Human
Histone-lysine N-methyltransferase SETMAR.
To be Published
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3F2U
 | | Crystal structure of human chromobox homolog 1 (CBX1) | | Descriptor: | Chromobox protein homolog 1 | | Authors: | Amaya, M.F, Ravichandran, M, Tempel, W, Wernimont, A.K, Loppnau, P, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Bountra, C, Botchkarev, A, Min, J, Ouyang, H, Structural Genomics Consortium (SGC) | | Deposit date: | 2008-10-30 | | Release date: | 2008-11-25 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structure of the complex of human chromobox homolog 1 (CBX1)
To be Published
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3F3D
 | | Crystal structure of LeuT bound to L-Methionine and sodium | | Descriptor: | METHIONINE, SODIUM ION, Transporter, ... | | Authors: | Singh, S.K, Piscitelli, C.L, Yamashita, A, Gouaux, E. | | Deposit date: | 2008-10-30 | | Release date: | 2008-12-23 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | A competitive inhibitor traps LeuT in an open-to-out conformation.
Science, 322, 2008
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3EXN
 | | Crystal structure of acetyltransferase from Thermus thermophilus HB8 | | Descriptor: | ACETYL COENZYME *A, CHLORIDE ION, Probable acetyltransferase | | Authors: | Nocek, B, Hatzos, C, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2008-10-16 | | Release date: | 2009-01-06 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structure of acetyltransferase from Thermus thermophilus HB8
To be Published
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