1Q57
 
 | | The Crystal Structure of the Bifunctional Primase-Helicase of Bacteriophage T7 | | Descriptor: | DNA primase/helicase | | Authors: | Toth, E.A, Li, Y, Sawaya, M.R, Cheng, Y, Ellenberger, T. | | Deposit date: | 2003-08-06 | | Release date: | 2003-11-25 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (3.45 Å) | | Cite: | The Crystal Structure of the Bifunctional Primase-Helicase of Bacteriophage T7
Mol.Cell, 12, 2003
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3ZZ0
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4D6V
 | | Crystal structure of signal transducing protein | | Descriptor: | G PROTEIN BETA SUBUNIT GIB2 | | Authors: | Ero, R, Dimitrova, V.T, Chen, Y, Bu, W, Feng, S, Liu, T, Wang, P, Xue, C, Tan, S.M, Gao, Y.G. | | Deposit date: | 2014-11-17 | | Release date: | 2015-03-18 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal Structure of Gib2, a Signal-Transducing Protein Scaffold Associated with Ribosomes in Cryptococcus Neoformans.
Sci.Rep., 5, 2015
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4BVV
 | | Identification of small molecule inhibitors selective for apo(a) kringles KIV-7, KIV-10 and KV. | | Descriptor: | 1-CYCLOPROPYL-6-FLUORO-4-OXO-7-PIPERAZIN-1-YL-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID, APOLIPOPROTEIN(A), SULFATE ION | | Authors: | Sandmark, J, Althage, M, Andersson, G.M.K, Antonsson, T, Blaho, S, Bodin, C, Bostrom, J, Chen, Y, Dahlen, A, Eriksson, P.O, Evertsson, E, Fex, T, Fjellstrom, O, Gustafsson, D, Hallberg, C, Hicks, R, Jarkvist, E, Johansson, C, Kalies, I, Kang, D, Svalstedt Karlsson, B, Kartberg, F, Legnehed, A, Lindqvist, A.M, Martinsson, S.A, Moberg, A, Petersson, A.U, Ridderstrom, M, Thelin, A, Tigerstrom, A, Vinblad, J, Xu, B, Knecht, W. | | Deposit date: | 2013-06-28 | | Release date: | 2014-07-16 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Small Molecules Used to Decipher the Pathophysiological Roles of the Kringle Domains Kiv-7, - 10 and Kv of Apolipoprotein(A)
To be Published
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2XIM
 | | ARGININE RESIDUES AS STABILIZING ELEMENTS IN PROTEINS | | Descriptor: | D-XYLOSE ISOMERASE, MAGNESIUM ION, Xylitol | | Authors: | Mrabet, N.T, Van Denbroek, A, Van Den Brande, I, Stanssens, P, Laroche, Y, Lambeir, A.-M, Matthyssens, G, Jenkins, J, Chiadmi, M, Vantilbeurgh, H, Rey, F, Janin, J, Quax, W.J, Lasters, I, Demaeyer, M, Wodak, S.J. | | Deposit date: | 1991-05-29 | | Release date: | 1993-04-15 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Arginine residues as stabilizing elements in proteins.
Biochemistry, 31, 1992
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4DDS
 | | CTX-M-9 class A beta-lactamase complexed with compound 11 | | Descriptor: | 3-(pyrimidin-2-yl)-N-[3-(1H-tetrazol-5-yl)phenyl]benzamide, Beta-lactamase, DIMETHYL SULFOXIDE | | Authors: | Nichols, D.A, Chen, Y. | | Deposit date: | 2012-01-19 | | Release date: | 2012-03-28 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (1.36 Å) | | Cite: | Structure-Based Design of Potent and Ligand-Efficient Inhibitors of CTX-M Class A Beta-Lactamase
J.Med.Chem., 55, 2012
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4DE0
 | | CTX-M-9 class A beta-lactamase complexed with compound 16 | | Descriptor: | Beta-lactamase, DIMETHYL SULFOXIDE, N-[3-(1H-tetrazol-5-yl)phenyl]-1H-benzimidazole-7-carboxamide | | Authors: | Nichols, D.N, Chen, Y. | | Deposit date: | 2012-01-19 | | Release date: | 2012-03-28 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.12 Å) | | Cite: | Structure-Based Design of Potent and Ligand-Efficient Inhibitors of CTX-M Class A Beta-Lactamase
J.Med.Chem., 55, 2012
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4DSR
 | | Crystal structure of peroxiredoxin Ahp1 from Saccharomyces cerevisiae in reduced form | | Descriptor: | Peroxiredoxin type-2 | | Authors: | Lian, F.M, Yu, J, Ma, X.X, Yu, X.J, Chen, Y, Zhou, C.Z. | | Deposit date: | 2012-02-19 | | Release date: | 2012-04-11 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.91 Å) | | Cite: | Structural Snapshots of Yeast Alkyl Hydroperoxide Reductase Ahp1 Peroxiredoxin Reveal a Novel Two-cysteine Mechanism of Electron Transfer to Eliminate Reactive Oxygen Species.
J.Biol.Chem., 287, 2012
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4DE2
 | | CTX-M-9 class A beta-lactamase complexed with compound 12 | | Descriptor: | 3-[(dimethylamino)methyl]-N-[3-(1H-tetrazol-5-yl)phenyl]benzamide, Beta-lactamase, DIMETHYL SULFOXIDE | | Authors: | Nichols, D.A, Chen, Y. | | Deposit date: | 2012-01-19 | | Release date: | 2012-03-28 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Structure-Based Design of Potent and Ligand-Efficient Inhibitors of CTX-M Class A Beta-Lactamase
J.Med.Chem., 55, 2012
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4DSQ
 | | Crystal structure of peroxiredoxin Ahp1 from Saccharomyces cerevisiae in oxidized form | | Descriptor: | Peroxiredoxin type-2 | | Authors: | Lian, F.M, Yu, J, Ma, X.X, Yu, X.J, Chen, Y, Zhou, C.Z. | | Deposit date: | 2012-02-19 | | Release date: | 2012-04-11 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural Snapshots of Yeast Alkyl Hydroperoxide Reductase Ahp1 Peroxiredoxin Reveal a Novel Two-cysteine Mechanism of Electron Transfer to Eliminate Reactive Oxygen Species
J.Biol.Chem., 287, 2012
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4DE1
 | | CTX-M-9 class A beta-lactamase complexed with compound 18 | | Descriptor: | Beta-lactamase, DIMETHYL SULFOXIDE, N-[3-(1H-tetrazol-5-yl)phenyl]-2H-indazole-5-carboxamide | | Authors: | Nichols, D.A, Chen, Y. | | Deposit date: | 2012-01-19 | | Release date: | 2012-03-28 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.26 Å) | | Cite: | Structure-Based Design of Potent and Ligand-Efficient Inhibitors of CTX-M Class A Beta-Lactamase
J.Med.Chem., 55, 2012
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1M6X
 | | Flpe-Holliday Junction Complex | | Descriptor: | Flp recombinase, Symmetrized FRT site | | Authors: | Conway, A.B, Chen, Y, Rice, P.A. | | Deposit date: | 2002-07-17 | | Release date: | 2003-02-04 | | Last modified: | 2021-10-27 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural Plasticity of the Flp-Holliday Junction Complex
J.Mol.Biol., 326, 2003
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3E29
 | | X-Ray structure of the protein Q7WE92_BORBR from thioesterase superfamily. Northeast Structural Genomics Consortium Target BoR214A. | | Descriptor: | uncharacterized protein Q7WE92_BORBR | | Authors: | Kuzin, A.P, Chen, Y, Setharaman, J, Wang, D, Mao, L, Foote, E.L, Xiao, R, Nair, R, Everett, J.K, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2008-08-05 | | Release date: | 2008-09-30 | | Last modified: | 2017-10-25 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | X-Ray structure of the protein Q7WE92_BORBR from thioesterase superfamily. Northeast Structural Genomics Consortium Target BoR214A.
To be Published
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3P9V
 | | High Resolution Crystal Structure of protein Maqu_3174 from Marinobacter aquaeolei, Northeast Structural Genomics Consortium Target MqR197 | | Descriptor: | Uncharacterized protein | | Authors: | Kuzin, A, Chen, Y, Seetharaman, J, Mao, M, Xiao, R, Ciccosanti, C, Wang, H, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2010-10-18 | | Release date: | 2010-10-27 | | Last modified: | 2012-02-22 | | Method: | X-RAY DIFFRACTION (1.78 Å) | | Cite: | Northeast Structural Genomics Consortium Target MqR197
To be published
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3PUT
 | | Crystal Structure of the CERT START domain (mutant V151E) from Rhizobium etli at the resolution 1.8A, Northeast Structural Genomics Consortium Target ReR239. | | Descriptor: | HEXANE-1,6-DIOL, Hypothetical conserved protein | | Authors: | Kuzin, A, Chen, Y, Seetharaman, J, Mao, M, Xiao, R, Ciccosanti, C, Wang, D, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2010-12-06 | | Release date: | 2010-12-22 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (1.828 Å) | | Cite: | Crystal Structure of the CERT START domain (mutant V151E) from Rhizobium etli at the resolution 1.8A, Northeast Structural Genomics Consortium Target ReR239.
To be Published
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3PIN
 | | Crystal structure of Mxr1 from Saccharomyces cerevisiae in complex with Trx2 | | Descriptor: | Peptide methionine sulfoxide reductase, Thioredoxin-2 | | Authors: | Ma, X.X, Guo, P.C, Shi, W.W, Luo, M, Tan, X.F, Chen, Y, Zhou, C.Z. | | Deposit date: | 2010-11-07 | | Release date: | 2011-02-23 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural plasticity of the thioredoxin recognition site of yeast methionine S-sulfoxide reductase Mxr1
J.Biol.Chem., 286, 2011
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3PIM
 | | Crystal structure of Mxr1 from Saccharomyces cerevisiae in unusual oxidized form | | Descriptor: | Peptide methionine sulfoxide reductase | | Authors: | Ma, X.X, Guo, P.C, Shi, W.W, Luo, M, Tan, X.F, Chen, Y, Zhou, C.Z. | | Deposit date: | 2010-11-07 | | Release date: | 2011-02-23 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural plasticity of the thioredoxin recognition site of yeast methionine S-sulfoxide reductase Mxr1
J.Biol.Chem., 286, 2011
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3EYX
 | | Crystal structure of Carbonic Anhydrase Nce103 from Saccharomyces cerevisiae | | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, Carbonic anhydrase, ... | | Authors: | Teng, Y.B, Jiang, Y.L, Chen, Y, Zhou, C.Z. | | Deposit date: | 2008-10-22 | | Release date: | 2009-09-15 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.04 Å) | | Cite: | Structural insights into the substrate tunnel of Saccharomyces cerevisiae carbonic anhydrase Nce103.
Bmc Struct.Biol., 9, 2009
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3FIA
 | | Crystal structure of the EH 1 domain from human intersectin-1 protein. Northeast Structural Genomics Consortium target HR3646e. | | Descriptor: | CALCIUM ION, Intersectin-1, SULFATE ION | | Authors: | Vorobiev, S.M, Chen, Y, Seetharaman, J, Devices, C, Zhao, L, Foote, E.L, Ciccosanti, C, Mao, L, Xiao, R, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2008-12-11 | | Release date: | 2008-12-30 | | Last modified: | 2021-10-20 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Crystal structure of the EH 1 domain from human intersectin-1 protein.
To be Published
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5YN8
 | | Crystal structure of MERS-CoV nsp16/nsp10 complex bound to SAH | | Descriptor: | S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION, nsp10 protein, ... | | Authors: | Wei, S.M, Yang, L, Ke, Z.H, Chen, Y, Guo, D.Y, Fan, C.P. | | Deposit date: | 2017-10-24 | | Release date: | 2018-12-05 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.97 Å) | | Cite: | Structural insights into the molecular mechanism of MERS Coronavirus RNA ribose 2'-O-methylation by nsp16/nsp10 protein complex
To Be Published
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5YNJ
 | | Crystal structure of MERS-CoV nsp16/nsp10 complex bound to m7GpppG | | Descriptor: | 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, ZINC ION, nsp10 protein, ... | | Authors: | Wei, S.M, Yang, L, Ke, Z.H, Chen, Y, Guo, D.Y, Fan, C.P. | | Deposit date: | 2017-10-24 | | Release date: | 2018-12-05 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.043 Å) | | Cite: | Structural insights into the molecular mechanism of MERS Coronavirus RNA ribose 2'-O-methylation by nsp16/nsp10 protein complex
To Be Published
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3D5N
 | | Crystal structure of the Q97W15_SULSO protein from Sulfolobus solfataricus. NESG target SsR125. | | Descriptor: | Q97W15_SULSO | | Authors: | Vorobiev, S.M, Chen, Y, Seetharaman, J, Lee, D, Foote, R.E, Maglaqui, M, Janjua, H, Xiao, R, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2008-05-16 | | Release date: | 2008-07-15 | | Last modified: | 2017-10-25 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal structure of the Q97W15_SULSO protein from Sulfolobus solfataricus. NESG target SsR125.
To be Published
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3PU2
 | | Crystal Structure of the Q3J4M4_RHOS4 protein from Rhodobacter sphaeroides. Northeast Structural Genomics Consortium Target RhR263. | | Descriptor: | uncharacterized protein | | Authors: | Vorobiev, S, Chen, Y, Seetharaman, J, Sahdev, S, Xiao, R, Ciccosanti, C, Wang, D, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2010-12-03 | | Release date: | 2010-12-15 | | Last modified: | 2012-02-22 | | Method: | X-RAY DIFFRACTION (2.606 Å) | | Cite: | Crystal Structure of the Q3J4M4_RHOS4 protein from Rhodobacter sphaeroides.
To be Published
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3QV0
 | | Crystal structure of Saccharomyces cerevisiae Mam33 | | Descriptor: | Mitochondrial acidic protein MAM33 | | Authors: | Jiang, Y.L, Pu, Y.G, Ma, X.X, Chen, Y, Zhou, C.Z. | | Deposit date: | 2011-02-24 | | Release date: | 2011-06-08 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal structures and putative interface of Saccharomyces cerevisiae mitochondrial matrix proteins Mmf1 and Mam33.
J.Struct.Biol., 175, 2011
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5YNI
 | | Crystal structure of MERS-CoV nsp16/nsp10 complex bound to SAM and m7GpppG | | Descriptor: | 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, S-ADENOSYLMETHIONINE, ZINC ION, ... | | Authors: | Wei, S.M, Yang, L, Ke, Z.H, Chen, Y, Guo, D.Y, Fan, C.P. | | Deposit date: | 2017-10-24 | | Release date: | 2018-12-05 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.07 Å) | | Cite: | Structural insights into the molecular mechanism of MERS Coronavirus RNA ribose 2'-O-methylation by nsp16/nsp10 protein complex
To Be Published
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