4E0D
 
 | | Binary complex of Bacillus DNA Polymerase I Large Fragment E658A and duplex DNA | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... | | Authors: | Wang, W, Beese, L.S. | | Deposit date: | 2012-03-02 | | Release date: | 2012-06-06 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.58 Å) | | Cite: | Structural factors that determine selectivity of a high fidelity DNA polymerase for deoxy-, dideoxy-, and ribonucleotides.
J.Biol.Chem., 287, 2012
|
|
4F2R
 | | DNA Polymerase I Large Fragment complex 3 | | Descriptor: | CYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*TP*GP*GP*GP*AP*GP*TP*CP*AP*GP*G)-3'), DNA (5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*(DOC))-3'), ... | | Authors: | Wang, W, Beese, L.S. | | Deposit date: | 2012-05-08 | | Release date: | 2013-07-24 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.63 Å) | | Cite: | Structures of a High-fidelity DNA Polymerase
to be published
|
|
8HZ8
 | |
4LJL
 | |
4LJK
 | |
8G7U
 | |
8G7T
 | | Cryo-EM structure of Riplet:RIG-I:dsRNA complex (end-end) | | Descriptor: | Antiviral innate immune response receptor RIG-I, E3 ubiquitin-protein ligase RNF135, ZINC ION, ... | | Authors: | Wang, W, Pyle, A.M. | | Deposit date: | 2023-02-17 | | Release date: | 2023-11-15 | | Last modified: | 2024-10-09 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | The E3 ligase Riplet promotes RIG-I signaling independent of RIG-I oligomerization.
Nat Commun, 14, 2023
|
|
8G7V
 | | Cryo-EM structure of Riplet:RIG-I:dsRNA complex (end-inter) | | Descriptor: | Antiviral innate immune response receptor RIG-I, E3 ubiquitin-protein ligase RNF135, ZINC ION, ... | | Authors: | Wang, W, Pyle, A.M. | | Deposit date: | 2023-02-17 | | Release date: | 2023-11-15 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | The E3 ligase Riplet promotes RIG-I signaling independent of RIG-I oligomerization.
Nat Commun, 14, 2023
|
|
4LJR
 | |
1PWK
 | | Structure of the Monomeric 8-kDa Dynein Light Chain and Mechanism of Domain Swapped Dimer Assembly | | Descriptor: | dynein light chain-2 | | Authors: | Wang, W, Lo, K.W.-H, Kan, H.-M, Fan, J.-S, Zhang, M. | | Deposit date: | 2003-07-02 | | Release date: | 2003-10-21 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Structure of the Monomeric 8-kDa Dynein Light Chain and Mechanism of the Domain-swapped Dimer Assembly
J.Biol.Chem., 278, 2003
|
|
3PX0
 | |
3PV8
 | |
3PX6
 | |
3PS5
 | | Crystal structure of the full-length Human Protein Tyrosine Phosphatase SHP-1 | | Descriptor: | SULFATE ION, Tyrosine-protein phosphatase non-receptor type 6 | | Authors: | Wang, W, Liu, L, Song, X, Mo, Y, Komma, C, Bellamy, H.D, Zhao, Z.J, Zhou, G.W. | | Deposit date: | 2010-11-30 | | Release date: | 2011-04-20 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Crystal structure of human protein tyrosine phosphatase SHP-1 in the open conformation.
J.Cell.Biochem., 112, 2011
|
|
3PX4
 | |
1PWJ
 | | Structure of the Monomeric 8-kDa Dynein Light Chain and Mechanism of Domain Swapped Dimer Assembly | | Descriptor: | dynein light chain-2 | | Authors: | Wang, W, Lo, K.W.-H, Kan, H.-M, Fan, J.-S, Zhang, M. | | Deposit date: | 2003-07-02 | | Release date: | 2003-10-21 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Structure of the Monomeric 8-kDa Dynein Light Chain and Mechanism of the Domain-swapped Dimer Assembly
J.Biol.Chem., 278, 2003
|
|
1ZDU
 | | The Crystal Structure of Human Liver Receptor Homologue-1 | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Nuclear receptor coactivator 2, Orphan nuclear receptor NR5A2, ... | | Authors: | Wang, W, Zhang, C, Marimuthu, A, Krupka, H.I, Tabrizizad, M, Shelloe, R, Mehra, U, Eng, K, Nguyen, H, Settachatgul, C, Powell, B, Milburn, M.V, West, B.L. | | Deposit date: | 2005-04-14 | | Release date: | 2005-05-24 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | The crystal structures of human steroidogenic factor-1 and liver receptor homologue-1
Proc.Natl.Acad.Sci.USA, 102, 2005
|
|
1ZDT
 | | The Crystal Structure of Human Steroidogenic Factor-1 | | Descriptor: | DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE, Nuclear receptor coactivator 2, Steroidogenic factor 1 | | Authors: | Wang, W, Zhang, C, Marimuthu, A, Krupka, H.I, Tabrizizad, M, Shelloe, R, Mehra, U, Eng, K, Nguyen, H, Settachatgul, C, Powell, B, Milburn, M.V, West, B.L. | | Deposit date: | 2005-04-14 | | Release date: | 2005-05-24 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | The crystal structures of human steroidogenic factor-1 and liver receptor homologue-1
Proc.Natl.Acad.Sci.USA, 102, 2005
|
|
7KZI
 | | Intermediate state (QQQ) of near full-length DnaK alternatively fused with a substrate peptide | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, Chaperone protein DnaK fused with substrate peptide,Chaperone protein DnaK fused with substrate peptide, ... | | Authors: | Wang, W, Hendrickson, W.A. | | Deposit date: | 2020-12-10 | | Release date: | 2021-05-12 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.82 Å) | | Cite: | Intermediates in allosteric equilibria of DnaK-ATP interactions with substrate peptides
Acta Crystallogr.,Sect.D, 77, 2021
|
|
7KRW
 | |
7KO2
 | |
7KRU
 | |
7KRV
 | | Stimulating state of disulfide-bridged Hsp70 DnaK | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Chaperone protein DnaK fused with substrate peptide, MAGNESIUM ION, ... | | Authors: | Wang, W, Hendrickson, W.A. | | Deposit date: | 2020-11-20 | | Release date: | 2021-09-15 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.92 Å) | | Cite: | Conformational equilibria in allosteric control of Hsp70 chaperones.
Mol.Cell, 81, 2021
|
|
7KRT
 | | Restraining state of a truncated Hsp70 DnaK | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Chaperone protein DnaK, MAGNESIUM ION | | Authors: | Wang, W, Hendrickson, W.A. | | Deposit date: | 2020-11-20 | | Release date: | 2021-09-15 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.79 Å) | | Cite: | Conformational equilibria in allosteric control of Hsp70 chaperones.
Mol.Cell, 81, 2021
|
|
7TNY
 | | Cryo-EM structure of RIG-I in complex with p2dsRNA | | Descriptor: | Antiviral innate immune response receptor RIG-I, ZINC ION, p2dsRNA | | Authors: | Wang, W, Pyle, A.M. | | Deposit date: | 2022-01-22 | | Release date: | 2022-11-02 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands.
Mol.Cell, 82, 2022
|
|
