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4RD2
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BU of 4rd2 by Molmil
Structure of aIF2-gamma H97A variant from Sulfolobus solfataricus bound to GDPNP
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Dubiez, E, Aleksandrov, A, Lazennec-Schurdevin, C, Mechulam, Y, Schmitt, E.
Deposit date:2014-09-18
Release date:2015-05-27
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.585 Å)
Cite:Identification of a second GTP-bound magnesium ion in archaeal initiation factor 2.
Nucleic Acids Res., 43, 2015
4RD4
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BU of 4rd4 by Molmil
Structure of aIF2 gamma from sulfolobus solfataricus bound to gdpnp
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Dubiez, E, Aleksandrov, A, Lazennec-Schurdevin, C, Mechulam, Y, Schmitt, E.
Deposit date:2014-09-18
Release date:2015-05-27
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Identification of a second GTP-bound magnesium ion in archaeal initiation factor 2.
Nucleic Acids Res., 43, 2015
4RCY
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BU of 4rcy by Molmil
Structure of aIF2-gamma D19A variant from Sulfolobus solfataricus bound to GTP
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Dubiez, E, Aleksandrov, A, Lazennec-Schurdevin, C, Mechulam, Y, Schmitt, E.
Deposit date:2014-09-18
Release date:2015-05-27
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Identification of a second GTP-bound magnesium ion in archaeal initiation factor 2.
Nucleic Acids Res., 43, 2015
4RD0
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BU of 4rd0 by Molmil
Structure of aIF2-gamma D19A variant from Sulfolobus solfataricus bound to GDP
Descriptor: CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Dubiez, E, Aleksandrov, A, Lazennec-Schurdevin, C, Mechulam, Y, Schmitt, E.
Deposit date:2014-09-18
Release date:2015-05-27
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.713 Å)
Cite:Identification of a second GTP-bound magnesium ion in archaeal initiation factor 2.
Nucleic Acids Res., 43, 2015
4ZGO
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BU of 4zgo by Molmil
Structure of C-terminally truncated Cdc123 from Schizosaccharomyces pombe
Descriptor: Cell division cycle protein 123
Authors:Panvert, M, Dubiez, E, Arnold, L, Perez, J, Seufert, W, Mechulam, Y, Schmitt, E.
Deposit date:2015-04-23
Release date:2015-09-30
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.063 Å)
Cite:Cdc123, a Cell Cycle Regulator Needed for eIF2 Assembly, Is an ATP-Grasp Protein with Unique Features.
Structure, 23, 2015
4ZGP
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BU of 4zgp by Molmil
Structure of Cdc123 from Schizosaccharomyces pombe
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Cell division cycle protein 123
Authors:Panvert, M, Dubiez, E, Arnold, L, Perez, J, Seufert, W, Mechulam, Y, Schmitt, E.
Deposit date:2015-04-23
Release date:2015-10-14
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Cdc123, a Cell Cycle Regulator Needed for eIF2 Assembly, Is an ATP-Grasp Protein with Unique Features.
Structure, 23, 2015
4ZGQ
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BU of 4zgq by Molmil
Structure of Cdc123 bound to eIF2-gammaDIII domain
Descriptor: Cell division cycle protein 123, Eukaryotic translation initiation factor 2 subunit gamma
Authors:Panvert, M, Dubiez, E, Arnold, L, Perez, J, Seufert, W, Mechulam, Y, Schmitt, E.
Deposit date:2015-04-23
Release date:2015-10-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:Cdc123, a Cell Cycle Regulator Needed for eIF2 Assembly, Is an ATP-Grasp Protein with Unique Features.
Structure, 23, 2015
4ZGN
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BU of 4zgn by Molmil
Structure Cdc123 complexed with the C-terminal domain of eIF2gamma
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cell division cycle protein 123, Eukaryotic translation initiation factor 2 subunit gamma, ...
Authors:Panvert, M, Dubiez, E, Arnold, L, Perez, J, Seufert, W, Mechulam, Y, Schmitt, E.
Deposit date:2015-04-23
Release date:2015-09-30
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Cdc123, a Cell Cycle Regulator Needed for eIF2 Assembly, Is an ATP-Grasp Protein with Unique Features.
Structure, 23, 2015
3CW5
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BU of 3cw5 by Molmil
E. coli Initiator tRNA
Descriptor: Initiator tRNA
Authors:Barraud, P, Schmitt, E, Mechulam, Y, Dardel, F, Tisne, C.
Deposit date:2008-04-21
Release date:2008-09-02
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:A unique conformation of the anticodon stem-loop is associated with the capacity of tRNAfMet to initiate protein synthesis.
Nucleic Acids Res., 36, 2008
7ZAH
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BU of 7zah by Molmil
Cryo-EM structure of a Pyrococcus abyssi 30S bound to Met-initiator tRNA, mRNA, aIF1A and aIF5B
Descriptor: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Coureux, P.D, Bourgeois, G, Mechulam, Y, Schmitt, E, Kazan, R.
Deposit date:2022-03-22
Release date:2022-08-03
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Role of aIF5B in archaeal translation initiation.
Nucleic Acids Res., 50, 2022
7ZAG
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BU of 7zag by Molmil
Cryo-EM structure of a Pyrococcus abyssi 30S bound to Met-initiator tRNA,mRNA, aIF1A and the C-terminal domain of aIF5B.
Descriptor: 30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, ...
Authors:Coureux, P.D, Bourgeois, G, Mechulam, Y, Schmitt, E, Kazan, R.
Deposit date:2022-03-22
Release date:2022-08-03
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2.77 Å)
Cite:Role of aIF5B in archaeal translation initiation.
Nucleic Acids Res., 50, 2022
7ZAI
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BU of 7zai by Molmil
Cryo-EM structure of a Pyrococcus abyssi 30S bound to Met-initiator tRNA, mRNA and aIF1A.
Descriptor: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Coureux, P.D, Bourgeois, G, Mechulam, Y, Schmitt, E, Kazan, R.
Deposit date:2022-03-22
Release date:2022-07-13
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Role of aIF5B in archaeal translation initiation.
Nucleic Acids Res., 50, 2022
7ZHG
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BU of 7zhg by Molmil
High-resolution cryo-EM structure of Pyrococcus abyssi 30S ribosomal subunit bound to mRNA and initiator tRNA anticodon stem-loop
Descriptor: 30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, ...
Authors:Kazan, R, Bourgeois, G, Mechulam, Y, Coureux, P.D, Schmitt, E.
Deposit date:2022-04-06
Release date:2022-06-29
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2.25 Å)
Cite:Role of aIF5B in archaeal translation initiation.
Nucleic Acids Res., 50, 2022
7ZKI
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BU of 7zki by Molmil
Cryo-EM structure of aIF1A:aIF5B:Met-tRNAiMet complex from a Pyrococcus abyssi 30S initiation complex
Descriptor: MAGNESIUM ION, METHIONINE, Met-tRNAiMet, ...
Authors:Coureux, P.D, Bourgeois, G, Mechulam, Y, Schmitt, E, Kazan, R.
Deposit date:2022-04-13
Release date:2022-07-20
Last modified:2022-08-31
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Role of aIF5B in archaeal translation initiation.
Nucleic Acids Res., 50, 2022
3CW6
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BU of 3cw6 by Molmil
E. coli Initiator tRNA
Descriptor: Initiator tRNA
Authors:Barraud, P, Schmitt, E, Mechulam, Y, Dardel, F, Tisne, C.
Deposit date:2008-04-21
Release date:2008-09-02
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:A unique conformation of the anticodon stem-loop is associated with the capacity of tRNAfMet to initiate protein synthesis.
Nucleic Acids Res., 36, 2008
6Q6R
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BU of 6q6r by Molmil
Recognition of different base tetrads by RHAU: X-ray crystal structure of G4 recognition motif bound to the 3-end tetrad of a DNA G-quadruplex
Descriptor: ATP-dependent DNA/RNA helicase DHX36, POTASSIUM ION, Parallel stranded DNA G-quadruplex
Authors:Heddi, B, Cheong, V.V, Schmitt, E, Mechulam, Y, Phan, A.T.
Deposit date:2018-12-11
Release date:2019-10-16
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Recognition of different base tetrads by RHAU (DHX36): X-ray crystal structure of the G4 recognition motif bound to the 3'-end tetrad of a DNA G-quadruplex.
J.Struct.Biol., 209, 2020
6QJO
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BU of 6qjo by Molmil
DNA containing both right- and left-handed parallel-stranded G-quadruplexes
Descriptor: DNA (28-MER), POTASSIUM ION
Authors:Winnerdy, F.R, Bakalar, B, Maity, A, Vandana, J.J, Schmitt, E, Mechulam, Y, Phan, A.T.
Deposit date:2019-01-24
Release date:2019-07-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:NMR solution and X-ray crystal structures of a DNA molecule containing both right- and left-handed parallel-stranded G-quadruplexes.
Nucleic Acids Res., 47, 2019
1XTY
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BU of 1xty by Molmil
Crystal structure of Sulfolobus solfataricus peptidyl-tRNA hydrolase
Descriptor: Peptidyl-tRNA hydrolase, SULFATE ION
Authors:Fromant, M, Schmitt, E, Mechulam, Y, Lazennec, C, Plateau, P, Blanquet, S.
Deposit date:2004-10-25
Release date:2005-03-22
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure at 1.8 A resolution and identification of active site residues of Sulfolobus solfataricus peptidyl-tRNA hydrolase.
Biochemistry, 44, 2005
3M4X
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BU of 3m4x by Molmil
Structure of a ribosomal methyltransferase
Descriptor: NOL1/NOP2/sun family protein
Authors:Galimand, M, Schmitt, E, Panvert, M, Mechulam, Y, Courvalin, P.
Deposit date:2010-03-12
Release date:2010-04-14
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Structure of an RNA methyltransferase
To be Published
1YZ6
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BU of 1yz6 by Molmil
Crystal structure of intact alpha subunit of aIF2 from Pyrococcus abyssi
Descriptor: Probable translation initiation factor 2 alpha subunit
Authors:Yatime, L, Schmitt, E, Blanquet, S, Mechulam, Y.
Deposit date:2005-02-28
Release date:2005-06-28
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.37 Å)
Cite:Structure-Function Relationships of the Intact aIF2alpha Subunit from the Archaeon Pyrococcus abyssi
Biochemistry, 44, 2005
1YZ7
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BU of 1yz7 by Molmil
Crystal structure of a C-terminal segment of the alpha subunit of aIF2 from Pyrococcus abyssi
Descriptor: Probable translation initiation factor 2 alpha subunit
Authors:Yatime, L, Schmitt, E, Blanquet, S, Mechulam, Y.
Deposit date:2005-02-28
Release date:2005-06-28
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Structure-Function Relationships of the Intact aIF2alpha Subunit from the Archaeon Pyrococcus abyssi
Biochemistry, 44, 2005
1JKE
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BU of 1jke by Molmil
D-Tyr tRNATyr deacylase from Escherichia coli
Descriptor: D-Tyr-tRNATyr deacylase, ZINC ION
Authors:Ferri-Fioni, M.L, Schmitt, E, Soutourina, J, Plateau, P, Mechulam, Y, Blanquet, S.
Deposit date:2001-07-12
Release date:2002-01-25
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structure of crystalline D-Tyr-tRNA(Tyr) deacylase. A representative of a new class of tRNA-dependent hydrolases.
J.Biol.Chem., 276, 2001
6SWC
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BU of 6swc by Molmil
IC2B model of cryo-EM structure of a full archaeal ribosomal translation initiation complex devoid of aIF1 in P. abyssi
Descriptor: 16S ribosomal rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Coureux, P.-D, Mechulam, Y, Schmitt, E.
Deposit date:2019-09-20
Release date:2020-02-19
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cryo-EM study of an archaeal 30S initiation complex gives insights into evolution of translation initiation.
Commun Biol, 3, 2020
6SWE
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BU of 6swe by Molmil
IC2 head of cryo-EM structure of a full archaeal ribosomal translation initiation complex devoid of aIF1 in P. abyssi
Descriptor: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S13, ...
Authors:Coureux, P.-D, Mechulam, Y, Schmitt, E.
Deposit date:2019-09-20
Release date:2020-02-19
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Cryo-EM study of an archaeal 30S initiation complex gives insights into evolution of translation initiation.
Commun Biol, 3, 2020
6SW9
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BU of 6sw9 by Molmil
IC2A model of cryo-EM structure of a full archaeal ribosomal translation initiation complex devoid of aIF1 in P. abyssi
Descriptor: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Coureux, P.-D, Mechulam, Y, Schmitt, E.
Deposit date:2019-09-20
Release date:2020-02-19
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Cryo-EM study of an archaeal 30S initiation complex gives insights into evolution of translation initiation.
Commun Biol, 3, 2020

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