7F4G
 
 | | Structure of RPAP2-bound RNA polymerase II | | Descriptor: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ... | | Authors: | Chen, X, Qi, Y, Wang, X, Li, J, Zhao, D, Xu, Y. | | Deposit date: | 2021-06-18 | | Release date: | 2021-07-07 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (2.78 Å) | | Cite: | RPAP2 regulates a transcription initiation checkpoint by inhibiting assembly of pre-initiation complex.
Cell Rep, 39, 2022
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4G4Q
 | | MutM containing F114A mutation bound to undamaged DNA | | Descriptor: | DNA (5'-D(*AP*GP*GP*TP*AP*GP*AP*CP*TP*CP*GP*GP*AP*CP*GP*C)-3'), DNA (5'-D(*TP*GP*CP*GP*TP*CP*CP*GP*AP*GP*(TX2)P*CP*TP*AP*CP*C)-3'), Formamidopyrimidine-DNA glycosylase, ... | | Authors: | Sung, R.J, Zhang, M, Qi, Y, Verdine, G.L. | | Deposit date: | 2012-07-16 | | Release date: | 2013-02-20 | | Last modified: | 2013-04-24 | | Method: | X-RAY DIFFRACTION (1.86 Å) | | Cite: | Structural and Biochemical Analysis of DNA Helix Invasion by the Bacterial 8-Oxoguanine DNA Glycosylase MutM.
J.Biol.Chem., 288, 2013
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4G4O
 | | MutM containing M77A mutation bound to oxoG-containing DNA | | Descriptor: | DNA (5'-D(*TP*GP*CP*GP*TP*CP*CP*(8OG)P*AP*GP*(TX2)P*CP*TP*AP*CP*C)-3'), DNA (5'-D(P*AP*GP*GP*TP*AP*GP*AP*CP*TP*CP*GP*GP*AP*CP*GP*C)-3'), Formamidopyrimidine-DNA glycosylase, ... | | Authors: | Sung, R.J, Zhang, M, Qi, Y, Verdine, G.L. | | Deposit date: | 2012-07-16 | | Release date: | 2013-02-20 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Structural and Biochemical Analysis of DNA Helix Invasion by the Bacterial 8-Oxoguanine DNA Glycosylase MutM.
J.Biol.Chem., 288, 2013
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4G4R
 | | MutM containing F114A mutation bound to oxoG-containing DNA | | Descriptor: | DNA (5'-D(*TP*GP*CP*GP*TP*CP*CP*(8OG)P*AP*GP*(TX2)P*CP*TP*AP*CP*C)-3'), DNA (5'-D(P*AP*GP*GP*TP*AP*GP*AP*CP*TP*CP*GP*GP*AP*CP*GP*C)-3'), Formamidopyrimidine-DNA glycosylase, ... | | Authors: | Sung, R.J, Zhang, M, Qi, Y, Verdine, G.L. | | Deposit date: | 2012-07-16 | | Release date: | 2013-02-20 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Structural and Biochemical Analysis of DNA Helix Invasion by the Bacterial 8-Oxoguanine DNA Glycosylase MutM.
J.Biol.Chem., 288, 2013
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6K9L
 | | 4.27 Angstrom resolution cryo-EM structure of human dimeric ATM kinase | | Descriptor: | Serine-protein kinase ATM | | Authors: | Xiao, J, Liu, M, Qi, Y, Chaban, Y, Gao, C, Tian, Y, Yu, Z, Li, J, Zhang, P, Xu, Y. | | Deposit date: | 2019-06-16 | | Release date: | 2019-12-25 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (4.27 Å) | | Cite: | Structural insights into the activation of ATM kinase.
Cell Res., 29, 2019
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6K9K
 | | Monomeric human ATM (Ataxia telangiectasia mutated) kinase | | Descriptor: | Serine-protein kinase ATM | | Authors: | Xiao, J, Liu, M, Qi, Y, Yuriy, C, Zhang, P, Xu, Y. | | Deposit date: | 2019-06-16 | | Release date: | 2019-12-25 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (7.82 Å) | | Cite: | Structural insights into the activation of ATM kinase.
Cell Res., 29, 2019
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7YCX
 | | The structure of INTAC-PEC complex | | Descriptor: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1,DNA-directed RNA polymerase II subunit RPB1, ... | | Authors: | Zheng, H, Jin, Q, Wang, X, Qi, Y, Liu, W, Ren, Y, Zhao, D, Chen, F.X, Cheng, J, Chen, X, Xu, Y. | | Deposit date: | 2022-07-02 | | Release date: | 2023-03-15 | | Last modified: | 2023-09-27 | | Method: | ELECTRON MICROSCOPY (4.18 Å) | | Cite: | Structural basis of INTAC-regulated transcription.
Protein Cell, 14, 2023
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5YEW
 | | Structural basis for GTP hydrolysis and conformational change of mitofusin 1 in mediating mitochondrial fusion | | Descriptor: | BERYLLIUM TRIFLUORIDE ION, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Yan, L, Qi, Y, Huang, X, Yu, C. | | Deposit date: | 2017-09-20 | | Release date: | 2018-01-31 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structural basis for GTP hydrolysis and conformational change of MFN1 in mediating membrane fusion
Nat. Struct. Mol. Biol., 25, 2018
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6L54
 | | Structure of SMG189 | | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Protein SMG8, ... | | Authors: | Xu, Y, Qi, Y. | | Deposit date: | 2019-10-22 | | Release date: | 2020-04-15 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.43 Å) | | Cite: | Cryo-EM structure of SMG1-SMG8-SMG9 complex.
Cell Res., 29, 2019
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6L53
 | | Structure of SMG1 | | Descriptor: | Serine/threonine-protein kinase SMG1 | | Authors: | Xu, Y, Qi, Y. | | Deposit date: | 2019-10-22 | | Release date: | 2020-04-15 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.63 Å) | | Cite: | Cryo-EM structure of SMG1-SMG8-SMG9 complex.
Cell Res., 29, 2019
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3SBJ
 | | MutM slanted complex 7 | | Descriptor: | 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*AP*GP*G)-3', 5'-D(P*CP*CP*TP*GP*GP*TP*(CX)P*TP*AP*CP*C)-3', Formamidopyrimidine-DNA glycosylase, ... | | Authors: | Sung, R.J, Zhang, M, Verdine, G.L. | | Deposit date: | 2011-06-05 | | Release date: | 2012-01-11 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Strandwise translocation of a DNA glycosylase on undamaged DNA.
Proc.Natl.Acad.Sci.USA, 109, 2012
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5GNR
 | | the structure of mini-MFN1 K88A in complex with GDP | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Mitofusin-1 | | Authors: | Yan, L, Yu, C, Ming, Z, Lou, Z, Rao, Z, Hu, J. | | Deposit date: | 2016-07-24 | | Release date: | 2016-11-23 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | BDLP-like folding of Mitofusin 1
To Be Published
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5GNU
 | | the structure of mini-MFN1 apo | | Descriptor: | Mitofusin-1 | | Authors: | Yan, L, Yu, C, Ming, Z, Lou, Z, Rao, Z, Lou, J. | | Deposit date: | 2016-07-25 | | Release date: | 2016-11-23 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (4.113 Å) | | Cite: | BDLP-like folding of Mitofusin 1
To Be Published
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4WWI
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2Y1R
 | | Structure of MecA121 & ClpC N-domain complex | | Descriptor: | ADAPTER PROTEIN MECA 1, NEGATIVE REGULATOR OF GENETIC COMPETENCE CLPC/MECB, S,R MESO-TARTARIC ACID | | Authors: | Wang, F, Mei, Z.Q, Wang, J.W, Shi, Y.G. | | Deposit date: | 2010-12-10 | | Release date: | 2011-03-16 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.595 Å) | | Cite: | Structure and Mechanism of the Hexameric Meca-Clpc Molecular Machine.
Nature, 471, 2011
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7EGF
 | | TFIID lobe A subcomplex | | Descriptor: | TATA-box-binding protein, Transcription initiation factor TFIID subunit 10, Transcription initiation factor TFIID subunit 11, ... | | Authors: | Chen, X, Wu, Z, Li, J, Zhao, D, Xu, Y. | | Deposit date: | 2021-03-24 | | Release date: | 2021-05-05 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (3.16 Å) | | Cite: | Structural insights into preinitiation complex assembly on core promoters.
Science, 2021
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7EGG
 | | TFIID lobe B subcomplex | | Descriptor: | Transcription initiation factor TFIID subunit 10, Transcription initiation factor TFIID subunit 12, Transcription initiation factor TFIID subunit 4, ... | | Authors: | Chen, X, Wu, Z, Li, J, Zhao, D, Xu, Y. | | Deposit date: | 2021-03-24 | | Release date: | 2021-05-05 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (2.77 Å) | | Cite: | Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
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7EGH
 | | TFIID lobe C subcomplex | | Descriptor: | DNA (45-MER), Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 2, ... | | Authors: | Chen, X, Wu, Z, Li, J, Zhao, D, Xu, Y. | | Deposit date: | 2021-03-24 | | Release date: | 2021-05-12 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (3.04 Å) | | Cite: | Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
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7EGI
 | | TFIID in rearranged conformation | | Descriptor: | TATA-box-binding protein, Transcription initiation factor IIA subunit 1, Transcription initiation factor IIA subunit 2, ... | | Authors: | Chen, X, Wu, Z, Li, J, Zhao, D, Xu, Y. | | Deposit date: | 2021-03-24 | | Release date: | 2021-05-12 | | Last modified: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (9.82 Å) | | Cite: | Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
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7EGD
 | | SCP promoter-bound TFIID-TFIIA in initial TBP-loading state | | Descriptor: | DNA (72-MER), TATA-box-binding protein, Transcription initiation factor IIA subunit 1, ... | | Authors: | Chen, X, Wu, Z, Li, J, Zhao, D, Xu, Y. | | Deposit date: | 2021-03-24 | | Release date: | 2021-05-12 | | Last modified: | 2024-11-06 | | Method: | ELECTRON MICROSCOPY (6.75 Å) | | Cite: | Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
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7EGJ
 | | SCP promoter-bound TFIID-TFIIA in post TBP-loading state | | Descriptor: | DNA (74-MER), TATA-box-binding protein, Transcription initiation factor IIA subunit 1, ... | | Authors: | Chen, X, Wu, Z, Li, J, Zhao, D, Xu, Y. | | Deposit date: | 2021-03-24 | | Release date: | 2021-05-12 | | Last modified: | 2024-11-06 | | Method: | ELECTRON MICROSCOPY (8.64 Å) | | Cite: | Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
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7EGE
 | | TFIID in canonical conformation | | Descriptor: | TATA-box-binding protein, Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 10, ... | | Authors: | Chen, X, Wu, Z, Li, J, Zhao, D, Xu, Y. | | Deposit date: | 2021-03-24 | | Release date: | 2021-05-12 | | Method: | ELECTRON MICROSCOPY (9 Å) | | Cite: | Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
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2Y1Q
 | | Crystal Structure of ClpC N-terminal Domain | | Descriptor: | NEGATIVE REGULATOR OF GENETIC COMPETENCE CLPC/MECB, SULFATE ION | | Authors: | Wang, F, Mei, Z.Q, Wang, J.W, Shi, Y.G. | | Deposit date: | 2010-12-10 | | Release date: | 2011-03-16 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structure and Mechanism of the Hexameric Meca-Clpc Molecular Machine.
Nature, 471, 2011
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5XJO
 | | Plant receptor ERL1-TMM in complex with peptide EPF1 | | Descriptor: | LRR receptor-like serine/threonine-protein kinase ERL1, Protein EPIDERMAL PATTERNING FACTOR 1, Protein TOO MANY MOUTHS | | Authors: | Chai, J, Lin, G, Zhang, L, Han, Z, Shpak, E.D, Yang, X. | | Deposit date: | 2017-05-03 | | Release date: | 2019-01-23 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (2.626 Å) | | Cite: | A receptor-like protein acts as a specificity switch for the regulation of stomatal development.
Genes Dev., 31, 2017
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5XKJ
 | | Crystal structure of plant receptor ERL1-TMM in complexe with EPF2 | | Descriptor: | LRR receptor-like serine/threonine-protein kinase ERL1, Protein EPIDERMAL PATTERNING FACTOR 2, Protein TOO MANY MOUTHS | | Authors: | Chai, J, Lin, G. | | Deposit date: | 2017-05-07 | | Release date: | 2019-01-23 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (3.475 Å) | | Cite: | A receptor-like protein acts as a specificity switch for the regulation of stomatal development.
Genes Dev., 31, 2017
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