6COZ
 
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1OTU
 | | Structure of the Escherichia coli ClC Chloride channel E148Q mutant and Fab Complex | | Descriptor: | CHLORIDE ION, Fab fragment (Heavy chain), Fab fragment (Light chain), ... | | Authors: | Dutzler, R, Campbell, E.B, MacKinnon, R. | | Deposit date: | 2003-03-23 | | Release date: | 2003-04-15 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Gating the Selectivity Filter in ClC Chloride Channels
Science, 300, 2003
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6C3P
 | | Cryo-EM structure of human KATP bound to ATP and ADP in propeller form | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ... | | Authors: | Lee, K.P.K, Chen, J, MacKinnon, R. | | Deposit date: | 2018-01-10 | | Release date: | 2018-01-24 | | Method: | ELECTRON MICROSCOPY (5.6 Å) | | Cite: | Molecular structure of human KATP in complex with ATP and ADP.
Elife, 6, 2017
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6C3O
 | | Cryo-EM structure of human KATP bound to ATP and ADP in quatrefoil form | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ... | | Authors: | Lee, K.P.K, Chen, J, MacKinnon, R. | | Deposit date: | 2018-01-10 | | Release date: | 2018-01-31 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Molecular structure of human KATP in complex with ATP and ADP
Elife, 6, 2017
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1LNQ
 | | CRYSTAL STRUCTURE OF MTHK AT 3.3 A | | Descriptor: | CALCIUM ION, POTASSIUM CHANNEL RELATED PROTEIN | | Authors: | Jiang, Y, Lee, A, Chen, J, Cadene, M, Chait, B.T, Mackinnon, R. | | Deposit date: | 2002-05-03 | | Release date: | 2002-06-19 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | CRYSTAL STRUCTURE AND MECHANISM OF A CALCIUM-GATED POTASSIUM CHANNEL
Nature, 417, 2002
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1KPK
 | | Crystal Structure of the ClC Chloride Channel from E. coli | | Descriptor: | putative channel transporter | | Authors: | Dutzler, R, Campbell, E.B, Cadene, M, Chait, B.T, MacKinnon, R. | | Deposit date: | 2001-12-31 | | Release date: | 2002-01-23 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | X-ray structure of a ClC chloride channel at 3.0 A reveals the molecular basis of
anion selectivity.
Nature, 415, 2002
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1KPL
 | | Crystal Structure of the ClC Chloride Channel from S. typhimurium | | Descriptor: | CHLORIDE ION, N-OCTANE, PENTADECANE, ... | | Authors: | Dutzler, R, Campbell, E.B, Cadene, M, Chait, B.T, MacKinnon, R. | | Deposit date: | 2001-12-31 | | Release date: | 2002-01-23 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | X-ray structure of a ClC chloride channel at 3.0 A reveals the molecular basis of
anion selectivity.
Nature, 415, 2002
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6PBY
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6PBX
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6UQF
 | | Human HCN1 channel in a hyperpolarized conformation | | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, MERCURY (II) ION, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 | | Authors: | Lee, C.-H, MacKinnon, R. | | Deposit date: | 2019-10-19 | | Release date: | 2019-12-11 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.04 Å) | | Cite: | Voltage Sensor Movements during Hyperpolarization in the HCN Channel.
Cell, 179, 2019
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6UWM
 | | Single particle cryo-EM structure of KvAP | | Descriptor: | Voltage-gated potassium channel | | Authors: | Tao, X, MacKinnon, R. | | Deposit date: | 2019-11-05 | | Release date: | 2019-12-04 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (5.9 Å) | | Cite: | Cryo-EM structure of the KvAP channel reveals a non-domain-swapped voltage sensor topology.
Elife, 8, 2019
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6UQG
 | | Human HCN1 channel Y289D mutant | | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 | | Authors: | Lee, C.-H, MacKinnon, R. | | Deposit date: | 2019-10-19 | | Release date: | 2019-12-11 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.54 Å) | | Cite: | Voltage Sensor Movements during Hyperpolarization in the HCN Channel.
Cell, 179, 2019
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6V35
 | | Cryo-EM structure of Ca2+-free hsSlo1-beta4 channel complex | | Descriptor: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... | | Authors: | Tao, X, MacKinnon, R. | | Deposit date: | 2019-11-25 | | Release date: | 2019-12-25 | | Last modified: | 2020-10-07 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Molecular structures of the human Slo1 K + channel in complex with beta 4.
Elife, 8, 2019
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6V22
 | | Cryo-EM structure of Ca2+-bound hsSlo1-beta4 channel complex | | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | Authors: | Tao, X, MacKinnon, R. | | Deposit date: | 2019-11-22 | | Release date: | 2019-12-25 | | Last modified: | 2020-10-07 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Molecular structures of the human Slo1 K + channel in complex with beta 4.
Elife, 8, 2019
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6V38
 | | Cryo-EM structure of Ca2+-bound hsSlo1 channel | | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CALCIUM ION, CHOLESTEROL, ... | | Authors: | Tao, X, MacKinnon, R. | | Deposit date: | 2019-11-25 | | Release date: | 2019-12-25 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Molecular structures of the human Slo1 K + channel in complex with beta 4.
Elife, 8, 2019
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6V3G
 | | Cryo-EM structure of Ca2+-free hsSlo1 channel | | Descriptor: | Calcium-activated potassium channel subunit alpha-1 | | Authors: | Tao, X, MacKinnon, R. | | Deposit date: | 2019-11-25 | | Release date: | 2019-12-25 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Molecular structures of the human Slo1 K + channel in complex with beta 4.
Elife, 8, 2019
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5VA2
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4JTC
 | | Crystal structure of Kv1.2-2.1 paddle chimera channel in complex with Charybdotoxin in Cs+ | | Descriptor: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CESIUM ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | Authors: | Banerjee, A, Lee, A, Campbell, E, MacKinnon, R. | | Deposit date: | 2013-03-23 | | Release date: | 2013-06-12 | | Last modified: | 2019-12-25 | | Method: | X-RAY DIFFRACTION (2.56 Å) | | Cite: | Structure of a pore-blocking toxin in complex with a eukaryotic voltage-dependent K(+) channel.
Elife, 2, 2013
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4KFM
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7S5T
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7S5V
 | | Human KATP channel in open conformation, focused on SUR | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ... | | Authors: | Zhao, C, MacKinnon, R. | | Deposit date: | 2021-09-12 | | Release date: | 2021-12-01 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Molecular structure of an open human K ATP channel.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7S61
 | | Human KATP channel in open conformation, focused on Kir and one SUR, position 5 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ... | | Authors: | Zhao, C, MacKinnon, R. | | Deposit date: | 2021-09-12 | | Release date: | 2021-12-01 | | Last modified: | 2021-12-08 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Molecular structure of an open human K ATP channel.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7S60
 | | Human KATP channel in open conformation, focused on Kir and one SUR, position 4 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ... | | Authors: | Zhao, C, MacKinnon, R. | | Deposit date: | 2021-09-12 | | Release date: | 2021-12-01 | | Last modified: | 2021-12-08 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Molecular structure of an open human K ATP channel.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7S5X
 | | Human KATP channel in open conformation, focused on Kir and one SUR, position 1 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ... | | Authors: | Zhao, C, MacKinnon, R. | | Deposit date: | 2021-09-12 | | Release date: | 2021-12-01 | | Last modified: | 2021-12-08 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Molecular structure of an open human K ATP channel.
Proc.Natl.Acad.Sci.USA, 118, 2021
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4JTD
 | | Crystal structure of Kv1.2-2.1 paddle chimera channel in complex with Lys27Met mutant of Charybdotoxin | | Descriptor: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, POTASSIUM ION, ... | | Authors: | Banerjee, A, Lee, A, Campbell, E, MacKinnon, R. | | Deposit date: | 2013-03-23 | | Release date: | 2013-06-12 | | Last modified: | 2019-12-25 | | Method: | X-RAY DIFFRACTION (2.54 Å) | | Cite: | Structure of a pore-blocking toxin in complex with a eukaryotic voltage-dependent K(+) channel.
Elife, 2, 2013
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