6P87
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![BU of 6p87 by Molmil](/molmil-images/mine/6p87) | E.coli LpxD in complex with compound 5 | Descriptor: | 3-hydroxy-7,7-dimethyl-2-phenyl-4-(thiophen-2-yl)-2,6,7,8-tetrahydro-5H-pyrazolo[3,4-b]quinolin-5-one, MAGNESIUM ION, N-[(R)-(1H-indol-3-yl)(thiophen-2-yl)methyl]-2-(2-methoxyphenoxy)-N-methylacetamide, ... | Authors: | Ma, X, Shia, S. | Deposit date: | 2019-06-06 | Release date: | 2019-08-28 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural and Biological Basis of Small Molecule Inhibition ofEscherichia coliLpxD Acyltransferase Essential for Lipopolysaccharide Biosynthesis. Acs Infect Dis., 6, 2020
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6P8B
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![BU of 6p8b by Molmil](/molmil-images/mine/6p8b) | E.coli LpxD in complex with peptide FITC-RJPXD33 | Descriptor: | 3-hydroxy-7,7-dimethyl-2-phenyl-4-(thiophen-2-yl)-2,6,7,8-tetrahydro-5H-pyrazolo[3,4-b]quinolin-5-one, FITC-RJPXD33, MAGNESIUM ION, ... | Authors: | Ma, X, Shia, S. | Deposit date: | 2019-06-06 | Release date: | 2019-08-28 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural and Biological Basis of Small Molecule Inhibition ofEscherichia coliLpxD Acyltransferase Essential for Lipopolysaccharide Biosynthesis. Acs Infect Dis., 6, 2020
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6P84
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![BU of 6p84 by Molmil](/molmil-images/mine/6p84) | E.coli LpxD in complex with compound 2o | Descriptor: | 3-hydroxy-7,7-dimethyl-2-phenyl-4-(thiophen-2-yl)-2,6,7,8-tetrahydro-5H-pyrazolo[3,4-b]quinolin-5-one, MAGNESIUM ION, UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase | Authors: | Ma, X, Shia, S. | Deposit date: | 2019-06-06 | Release date: | 2019-08-28 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural and Biological Basis of Small Molecule Inhibition ofEscherichia coliLpxD Acyltransferase Essential for Lipopolysaccharide Biosynthesis. Acs Infect Dis., 6, 2020
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6P8A
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![BU of 6p8a by Molmil](/molmil-images/mine/6p8a) | E.coli LpxD in complex with compound 8.1 | Descriptor: | 2-[4,6-dimethyl-3-(1H-pyrrol-1-yl)-1H-pyrazolo[3,4-b]pyridin-1-yl]-N-[3-(morpholin-4-yl)propyl]acetamide, 3-hydroxy-7,7-dimethyl-2-phenyl-4-(thiophen-2-yl)-2,6,7,8-tetrahydro-5H-pyrazolo[3,4-b]quinolin-5-one, MAGNESIUM ION, ... | Authors: | Ma, X, Shia, S. | Deposit date: | 2019-06-06 | Release date: | 2019-08-28 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural and Biological Basis of Small Molecule Inhibition ofEscherichia coliLpxD Acyltransferase Essential for Lipopolysaccharide Biosynthesis. Acs Infect Dis., 6, 2020
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6P83
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![BU of 6p83 by Molmil](/molmil-images/mine/6p83) | E.coli LpxD in complex with compound 1o | Descriptor: | 4-(2-chlorophenyl)-3-hydroxy-7,7-dimethyl-2-phenyl-2,6,7,8-tetrahydro-5H-pyrazolo[3,4-b]quinolin-5-one, MAGNESIUM ION, UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase | Authors: | Ma, X, Shia, S. | Deposit date: | 2019-06-06 | Release date: | 2019-08-28 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural and Biological Basis of Small Molecule Inhibition ofEscherichia coliLpxD Acyltransferase Essential for Lipopolysaccharide Biosynthesis. Acs Infect Dis., 6, 2020
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6KS9
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![BU of 6ks9 by Molmil](/molmil-images/mine/6ks9) | |
6KSA
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![BU of 6ksa by Molmil](/molmil-images/mine/6ksa) | |
6KSB
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![BU of 6ksb by Molmil](/molmil-images/mine/6ksb) | |
6KW4
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![BU of 6kw4 by Molmil](/molmil-images/mine/6kw4) | The ClassB RSC-Nucleosome Complex | Descriptor: | Actin-like protein ARP9, Actin-related protein 7, Chromatin structure-remodeling complex protein RSC3, ... | Authors: | Ye, Y.P, Wu, H, Chen, K.J, Verma, N, Cairns, B, Gao, N, Chen, Z.C. | Deposit date: | 2019-09-06 | Release date: | 2019-11-13 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (7.55 Å) | Cite: | Structure of the RSC complex bound to the nucleosome. Science, 366, 2019
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6LQ7
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![BU of 6lq7 by Molmil](/molmil-images/mine/6lq7) | |
6LQ3
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![BU of 6lq3 by Molmil](/molmil-images/mine/6lq3) | |
7WK0
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![BU of 7wk0 by Molmil](/molmil-images/mine/7wk0) | Local refine of Omicron spike bitrimer with 6m6 antibody | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 6m6 heavy chain, 6m6 light chain, ... | Authors: | Zhan, W.Q, Zhang, X, Chen, Z.G, Sun, L. | Deposit date: | 2022-01-08 | Release date: | 2022-07-13 | Last modified: | 2022-09-14 | Method: | ELECTRON MICROSCOPY (3.32 Å) | Cite: | A broadly neutralizing antibody against SARS-CoV-2 Omicron variant infection exhibiting a novel trimer dimer conformation in spike protein binding. Cell Res., 32, 2022
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7WJY
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![BU of 7wjy by Molmil](/molmil-images/mine/7wjy) | Omicron spike trimer with 6m6 antibody | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 6m6 heavy chain, 6m6 light chain, ... | Authors: | Zhan, W.Q, Zhang, X, Chen, Z.G, Sun, L. | Deposit date: | 2022-01-08 | Release date: | 2022-07-13 | Last modified: | 2022-09-14 | Method: | ELECTRON MICROSCOPY (3.24 Å) | Cite: | A broadly neutralizing antibody against SARS-CoV-2 Omicron variant infection exhibiting a novel trimer dimer conformation in spike protein binding. Cell Res., 32, 2022
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7WJZ
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![BU of 7wjz by Molmil](/molmil-images/mine/7wjz) | Omicron Spike bitrimer with 6m6 antibody | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 6m6 heavy chain, 6m6 light chain, ... | Authors: | Zhan, W.Q, Zhang, X, Chen, Z.G, Sun, L. | Deposit date: | 2022-01-08 | Release date: | 2022-07-13 | Last modified: | 2022-09-14 | Method: | ELECTRON MICROSCOPY (3.34 Å) | Cite: | A broadly neutralizing antibody against SARS-CoV-2 Omicron variant infection exhibiting a novel trimer dimer conformation in spike protein binding. Cell Res., 32, 2022
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6LT8
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![BU of 6lt8 by Molmil](/molmil-images/mine/6lt8) | HSP90 in complex with KW-2478 | Descriptor: | 2-[2-ethyl-6-[3-methoxy-4-(2-morpholin-4-ylethoxy)phenyl]carbonyl-3,5-bis(oxidanyl)phenyl]-~{N},~{N}-bis(2-methoxyethyl)ethanamide, Heat shock protein HSP 90-alpha | Authors: | Cao, H.L. | Deposit date: | 2020-01-21 | Release date: | 2021-01-27 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.593 Å) | Cite: | Anti-NSCLC activity in vitro of Hsp90 N inhibitor KW-2478 and complex crystal structure determination of Hsp90 N -KW-2478. J.Struct.Biol., 213, 2021
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7E6T
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![BU of 7e6t by Molmil](/molmil-images/mine/7e6t) | Structural insights into the activation of human calcium-sensing receptor | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CYCLOMETHYLTRYPTOPHAN, ... | Authors: | Geng, Y, Chen, X.C, Wang, L, Cui, Q.Q, Ding, Z.Y, Han, L, Kou, Y.J, Zhang, W.Q, Wang, H.N, Jia, X.M, Dai, M, Shi, Z.Z, Li, Y.Y, Li, X.Y. | Deposit date: | 2021-02-24 | Release date: | 2021-09-22 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural insights into the activation of human calcium-sensing receptor. Elife, 10, 2021
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7E6U
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![BU of 7e6u by Molmil](/molmil-images/mine/7e6u) | the complex of inactive CaSR and NB2D11 | Descriptor: | Extracellular calcium-sensing receptor, NB-2D11 | Authors: | Geng, Y, Chen, X.C, Wang, L, Cui, Q.Q, Ding, Z.Y, Han, L, Kou, Y.J, Zhang, W.Q, Wang, H.N, Jia, X.M, Dai, M, Shi, Z.Z, Li, Y.Y, Li, X.Y. | Deposit date: | 2021-02-24 | Release date: | 2021-09-22 | Method: | ELECTRON MICROSCOPY (6 Å) | Cite: | Structural insights into the activation of human calcium-sensing receptor. Elife, 10, 2021
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6L8Q
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![BU of 6l8q by Molmil](/molmil-images/mine/6l8q) | Complex structure of bat CD26 and MERS-RBD | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Dipeptidyl peptidase 4, ... | Authors: | Yuan, Y. | Deposit date: | 2019-11-07 | Release date: | 2019-12-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Molecular Basis of Binding between Middle East Respiratory Syndrome Coronavirus and CD26 from Seven Bat Species. J.Virol., 94, 2020
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7CPX
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![BU of 7cpx by Molmil](/molmil-images/mine/7cpx) | Lovastatin nonaketide synthase | Descriptor: | Lovastatin nonaketide synthase, polyketide synthase component, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Wang, J, Wang, Z. | Deposit date: | 2020-08-08 | Release date: | 2021-01-13 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (2.91 Å) | Cite: | Structural basis for the biosynthesis of lovastatin. Nat Commun, 12, 2021
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7YR5
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![BU of 7yr5 by Molmil](/molmil-images/mine/7yr5) | |
7D2G
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![BU of 7d2g by Molmil](/molmil-images/mine/7d2g) | Coiled-coil structure of liprin-alpha2_H2delC | Descriptor: | GLYCEROL, Liprin-alpha-2 | Authors: | Liang, M, Wei, Z. | Deposit date: | 2020-09-16 | Release date: | 2021-04-07 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Oligomerized liprin-alpha promotes phase separation of ELKS for compartmentalization of presynaptic active zone proteins. Cell Rep, 34, 2021
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7D2E
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![BU of 7d2e by Molmil](/molmil-images/mine/7d2e) | Tetrameric coiled-coil structure of liprin-alpha2_H3 | Descriptor: | Liprin-alpha-2 | Authors: | Liang, M, Wei, Z. | Deposit date: | 2020-09-16 | Release date: | 2021-04-07 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Oligomerized liprin-alpha promotes phase separation of ELKS for compartmentalization of presynaptic active zone proteins. Cell Rep, 34, 2021
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7D2H
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![BU of 7d2h by Molmil](/molmil-images/mine/7d2h) | Tetrameric coiled-coil structure of liprin-alpha2_H2 | Descriptor: | GLYCEROL, Liprin-alpha-2 | Authors: | Liang, M, Wei, Z. | Deposit date: | 2020-09-16 | Release date: | 2021-04-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Oligomerized liprin-alpha promotes phase separation of ELKS for compartmentalization of presynaptic active zone proteins. Cell Rep, 34, 2021
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7CYA
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![BU of 7cya by Molmil](/molmil-images/mine/7cya) | Saimiri boliviensis boliviensis galectin-13 with lactose | Descriptor: | Galectin, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | Authors: | Su, J. | Deposit date: | 2020-09-03 | Release date: | 2021-06-16 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.71 Å) | Cite: | Actin binding to galectin-13/placental protein-13 occurs independently of the galectin canonical ligand-binding site. Glycobiology, 31, 2021
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7CYB
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![BU of 7cyb by Molmil](/molmil-images/mine/7cyb) | Saimiri boliviensis boliviensis galectin-13 with glycerol | Descriptor: | GLYCEROL, Galectin | Authors: | Su, J. | Deposit date: | 2020-09-03 | Release date: | 2021-06-16 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Actin binding to galectin-13/placental protein-13 occurs independently of the galectin canonical ligand-binding site. Glycobiology, 31, 2021
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