6WHC
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![BU of 6whc by Molmil](/molmil-images/mine/6whc) | CryoEM Structure of the glucagon receptor with a dual-agonist peptide | Descriptor: | Dual-agonist peptide, Glucagon receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Belousoff, M.J, Sexton, P, Danev, R. | Deposit date: | 2020-04-07 | Release date: | 2020-05-27 | Last modified: | 2020-07-22 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-electron microscopy structure of the glucagon receptor with a dual-agonist peptide. J.Biol.Chem., 295, 2020
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6R4C
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![BU of 6r4c by Molmil](/molmil-images/mine/6r4c) | Aurora-A in complex with shape-diverse fragment 57 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Aurora kinase A, CHLORIDE ION, ... | Authors: | Bayliss, R, McIntyre, P.J. | Deposit date: | 2019-03-22 | Release date: | 2019-05-01 | Last modified: | 2019-07-10 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Construction of a Shape-Diverse Fragment Set: Design, Synthesis and Screen against Aurora-A Kinase. Chemistry, 25, 2019
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6R4A
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![BU of 6r4a by Molmil](/molmil-images/mine/6r4a) | Aurora-A in complex with shape-diverse fragment 55 | Descriptor: | 2-(benzimidazol-1-yl)-~{N}-(2-phenylethyl)ethanamide, ADENOSINE-5'-DIPHOSPHATE, Aurora kinase A, ... | Authors: | Bayliss, R, McIntyre, P.J. | Deposit date: | 2019-03-22 | Release date: | 2019-05-08 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.937 Å) | Cite: | Construction of a Shape-Diverse Fragment Set: Design, Synthesis and Screen against Aurora-A Kinase. Chemistry, 25, 2019
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6R4B
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![BU of 6r4b by Molmil](/molmil-images/mine/6r4b) | Aurora-A in complex with shape-diverse fragment 56 | Descriptor: | (6~{S})-6-[2,4-bis(fluoranyl)phenyl]-~{N},~{N},4-trimethyl-2-oxidanylidene-5,6-dihydro-1~{H}-pyrimidine-5-carboxamide, ADENOSINE-5'-DIPHOSPHATE, Aurora kinase A, ... | Authors: | Bayliss, R, McIntyre, P.J. | Deposit date: | 2019-03-22 | Release date: | 2019-05-08 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Construction of a Shape-Diverse Fragment Set: Design, Synthesis and Screen against Aurora-A Kinase. Chemistry, 25, 2019
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6R49
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![BU of 6r49 by Molmil](/molmil-images/mine/6r49) | Aurora-A in complex with shape-diverse fragment 39 | Descriptor: | (1~{S},10~{S})-12-cyclopropyl-1-oxidanyl-10-propan-2-yl-9,12-diazatricyclo[8.2.1.0^{2,7}]trideca-2(7),3,5-trien-11-one, ADENOSINE-5'-DIPHOSPHATE, Aurora kinase A, ... | Authors: | Bayliss, R, McIntyre, P.J. | Deposit date: | 2019-03-22 | Release date: | 2019-05-08 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.209 Å) | Cite: | Construction of a Shape-Diverse Fragment Set: Design, Synthesis and Screen against Aurora-A Kinase. Chemistry, 25, 2019
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6R4D
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![BU of 6r4d by Molmil](/molmil-images/mine/6r4d) | Aurora-A in complex with shape-diverse fragment 58 | Descriptor: | (1~{S},10~{S})-12-cyclobutyl-5-methyl-1-oxidanyl-10-propan-2-yl-9,12-diazatricyclo[8.2.1.0^{2,7}]trideca-2(7),3,5-trien-11-one, ADENOSINE-5'-DIPHOSPHATE, Aurora kinase A, ... | Authors: | Bayliss, R, McIntyre, P.J. | Deposit date: | 2019-03-22 | Release date: | 2019-05-08 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.009 Å) | Cite: | Construction of a Shape-Diverse Fragment Set: Design, Synthesis and Screen against Aurora-A Kinase. Chemistry, 25, 2019
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5DD6
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![BU of 5dd6 by Molmil](/molmil-images/mine/5dd6) | |
5DD3
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![BU of 5dd3 by Molmil](/molmil-images/mine/5dd3) | |
5DD5
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![BU of 5dd5 by Molmil](/molmil-images/mine/5dd5) | |
1YWQ
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![BU of 1ywq by Molmil](/molmil-images/mine/1ywq) | |
3LMB
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![BU of 3lmb by Molmil](/molmil-images/mine/3lmb) | The crystal structure of the protein OLEI01261 with unknown function from Chlorobaculum tepidum TLS | Descriptor: | Uncharacterized protein | Authors: | Zhang, R, Evdokimova, E, Egorova, O, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2010-01-29 | Release date: | 2010-03-16 | Last modified: | 2013-08-07 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Genome sequence and functional genomic analysis of the oil-degrading bacterium Oleispira antarctica. Nat Commun, 4, 2013
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3NRV
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![BU of 3nrv by Molmil](/molmil-images/mine/3nrv) | |
3GA9
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![BU of 3ga9 by Molmil](/molmil-images/mine/3ga9) | Crystal structure of Bacillus anthracis transpeptidase enzyme CapD, crystal form II | Descriptor: | Capsule biosynthesis protein capD, GLUTAMIC ACID | Authors: | Zhang, R, Wu, R, Richter, S, Anderson, V.J, Missiakas, D, Joachimiak, A. | Deposit date: | 2009-02-16 | Release date: | 2009-06-16 | Last modified: | 2018-01-24 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal Structure of Bacillus anthracis Transpeptidase Enzyme CapD. J.Biol.Chem., 284, 2009
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8I7X
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![BU of 8i7x by Molmil](/molmil-images/mine/8i7x) | Crystal structure of human ClpP in complex with ZG36 | Descriptor: | (6S,9aS)-N-[(4-bromophenyl)methyl]-6-[(2S)-butan-2-yl]-8-[(4-methoxynaphthalen-1-yl)methyl]-4,7-bis(oxidanylidene)-3,6,9,9a-tetrahydro-2H-pyrazino[1,2-a]pyrimidine-1-carboxamide, ATP-dependent Clp protease proteolytic subunit, mitochondrial | Authors: | Wang, P.Y, Gan, J.H, Yang, C.-G. | Deposit date: | 2023-02-02 | Release date: | 2023-07-19 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Assessment of the structure-activity relationship and antileukemic activity of diacylpyramide compounds as human ClpP agonists. Eur.J.Med.Chem., 258, 2023
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3G9K
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![BU of 3g9k by Molmil](/molmil-images/mine/3g9k) | Crystal structure of Bacillus anthracis transpeptidase enzyme CapD | Descriptor: | Capsule biosynthesis protein capD, GLUTAMIC ACID | Authors: | Zhang, R, Wu, R, Richter, S, Anderson, V.J, Missiakas, D, Joachimiak, A. | Deposit date: | 2009-02-13 | Release date: | 2009-06-16 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Crystal Structure of Bacillus anthracis Transpeptidase Enzyme CapD. J.Biol.Chem., 284, 2009
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8D6K
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![BU of 8d6k by Molmil](/molmil-images/mine/8d6k) | Sco GlgEI-V279S in complex with cyclohexyl carbasugar | Descriptor: | (1R,4S,5S,6R)-4-(cyclohexylamino)-5,6-dihydroxy-2-(hydroxymethyl)cyclohex-2-en-1-yl alpha-D-glucopyranoside, Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase 1, DI(HYDROXYETHYL)ETHER | Authors: | Jayasinghe, T.J, Ronning, D.R. | Deposit date: | 2022-06-06 | Release date: | 2022-10-19 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.73 Å) | Cite: | Synthesis of C 7 /C 8 -cyclitols and C 7 N-aminocyclitols from maltose and X-ray crystal structure of Streptomyces coelicolor GlgEI V279S in a complex with an amylostatin GXG-like derivative. Front Chem, 10, 2022
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3SWJ
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![BU of 3swj by Molmil](/molmil-images/mine/3swj) | Crystal structure of Campylobacter jejuni ChuZ | Descriptor: | AZIDE ION, PROTOPORPHYRIN IX CONTAINING FE, Putative uncharacterized protein | Authors: | Hu, Y. | Deposit date: | 2011-07-14 | Release date: | 2011-11-09 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.409 Å) | Cite: | Crystal structure of Campylobacter jejuni ChuZ: a split-barrel family heme oxygenase with a novel heme-binding mode. Biochem.Biophys.Res.Commun., 415, 2011
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7EAU
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![BU of 7eau by Molmil](/molmil-images/mine/7eau) | SIB1, an effector of Colletotrichum orbiculare | Descriptor: | SIN1 | Authors: | Mori, M, Ohki, S, Kurita, J. | Deposit date: | 2021-03-08 | Release date: | 2021-11-03 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Fungal effector SIB1 of Colletotrichum orbiculare has unique structural features and can suppress plant immunity in Nicotiana benthamiana. J.Biol.Chem., 297, 2021
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7CBJ
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![BU of 7cbj by Molmil](/molmil-images/mine/7cbj) | Crystal structure of PDE4D catalytic domain in complex with compound 36 | Descriptor: | (1S)-1-[(7-chloranyl-1H-indol-3-yl)methyl]-6,7-dimethoxy-3,4-dihydro-1H-isoquinoline-2-carbaldehyde, 1,2-ETHANEDIOL, MAGNESIUM ION, ... | Authors: | Zhang, X.L, Xu, Y.C. | Deposit date: | 2020-06-12 | Release date: | 2021-06-16 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Design, synthesis, and biological evaluation of tetrahydroisoquinolines derivatives as novel, selective PDE4 inhibitors for antipsoriasis treatment. Eur.J.Med.Chem., 211, 2021
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1TMH
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1L3L
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![BU of 1l3l by Molmil](/molmil-images/mine/1l3l) | Crystal structure of a bacterial quorum-sensing transcription factor complexed with pheromone and DNA | Descriptor: | 3-OXO-OCTANOIC ACID (2-OXO-TETRAHYDRO-FURAN-3-YL)-AMIDE, 5'-D(*GP*AP*TP*GP*TP*GP*CP*AP*GP*AP*TP*CP*TP*GP*CP*AP*CP*AP*TP*C)-3', Transcriptional activator protein traR | Authors: | Zhang, R, Pappas, T, Brace, J.L, Miller, P.C, Oulmassov, T, Molyneaux, J.M, Anderson, J.C, Bashkin, J.K, Winans, S.C, Joachimiak, A. | Deposit date: | 2002-02-27 | Release date: | 2002-07-03 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | Structure of a bacterial quorum-sensing transcription factor complexed with pheromone and DNA. Nature, 417, 2002
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7CBQ
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![BU of 7cbq by Molmil](/molmil-images/mine/7cbq) | Crystal structure of PDE4D catalytic domain in complex with Apremilast | Descriptor: | 1,2-ETHANEDIOL, MAGNESIUM ION, N-{2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}acetamide, ... | Authors: | Zhang, X.L, Xu, Y.C. | Deposit date: | 2020-06-13 | Release date: | 2021-01-27 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | Design, synthesis, and biological evaluation of tetrahydroisoquinolines derivatives as novel, selective PDE4 inhibitors for antipsoriasis treatment. Eur.J.Med.Chem., 211, 2021
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1ILV
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![BU of 1ilv by Molmil](/molmil-images/mine/1ilv) | Crystal Structure Analysis of the TM107 | Descriptor: | STATIONARY-PHASE SURVIVAL PROTEIN SURE HOMOLOG | Authors: | Zhang, R, Joachimiak, A, Edwards, A, Savchenko, A, Beasley, S, Evdokimova, E, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2001-05-08 | Release date: | 2001-10-10 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of Thermotoga maritima stationary phase survival protein SurE: a novel acid phosphatase. Structure, 9, 2001
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1P99
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![BU of 1p99 by Molmil](/molmil-images/mine/1p99) | 1.7A crystal structure of protein PG110 from Staphylococcus aureus | Descriptor: | GLYCINE, Hypothetical protein PG110, METHIONINE | Authors: | Zhang, R, Zhou, M, Joachimiak, G, Schneewind, O, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2003-05-09 | Release date: | 2004-01-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The membrane-associated lipoprotein-9 GmpC from Staphylococcus aureus binds the dipeptide GlyMet via side chain interactions. Biochemistry, 43, 2004
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7VEG
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![BU of 7veg by Molmil](/molmil-images/mine/7veg) | Understanding NH-pi interaction between Gln and Phe | Descriptor: | (2~{S},4~{R})-4-oxidanylpyrrolidine-2-carboxamide, ACETYLAMINO-ACETIC ACID, peptide | Authors: | Fan, S, Xu, F. | Deposit date: | 2021-09-08 | Release date: | 2022-10-19 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.385 Å) | Cite: | Structural Achievability of an NH-pi Interaction between Gln and Phe in a Crystal Structure of a Collagen-like Peptide. Biomolecules, 12, 2022
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