3O38
| |
6WNG
| |
3PZY
| |
7AZN
| Structure of mouse AsterC (GramD1c) with a new cholesterol-derived compound | Descriptor: | 20alpha-hydroxy-20-(5-methylhexyl)cholesterol, ETHANOL, GLYCEROL, ... | Authors: | Romartinez-Alonso, B, Sirvydis, K, Kim, Y, Xiao, X, Jung, M, Tontonoz, P, Schwabe, J. | Deposit date: | 2020-11-16 | Release date: | 2021-01-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | Selective Aster inhibitors distinguish vesicular and nonvesicular sterol transport mechanisms. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
3NJD
| |
7UMP
| CRYSTAL STRUCTURE OF PHD2 CATALYTIC DOMAIN (CID 7465) IN COMPLEX WITH AKB-6548 AT 1.8 A RESOLUTION | Descriptor: | 1,2-ETHANEDIOL, Egl nine homolog 1, FE (II) ION, ... | Authors: | Davie, D.R, Abendroth, J, Boyd, J. | Deposit date: | 2022-04-07 | Release date: | 2022-05-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Preclinical Characterization of Vadadustat (AKB-6548), an Oral Small Molecule Hypoxia-Inducible Factor Prolyl-4-Hydroxylase Inhibitor, for the Potential Treatment of Renal Anemia. J.Pharmacol.Exp.Ther., 383, 2022
|
|
3RD8
| |
3PPI
| |
3DMS
| |
3R6O
| |
3FI3
| Crystal structure of JNK3 with indazole inhibitor, SR-3737 | Descriptor: | 1,2-ETHANEDIOL, 3-{5-[(2-fluorophenyl)amino]-1H-indazol-1-yl}-N-(3,4,5-trimethoxyphenyl)benzamide, Mitogen-activated protein kinase 10 | Authors: | Habel, J.E, Duckett, D, LoGrasso, P. | Deposit date: | 2008-12-10 | Release date: | 2009-03-03 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure-activity relationships and X-ray structures describing the selectivity of aminopyrazole inhibitors for c-Jun N-terminal kinase 3 (JNK3) over p38. J.Biol.Chem., 284, 2009
|
|
3OC6
| |
4DXL
| |
3P4T
| Crystal structure of a putative acyl-CoA dehydrogenase from Mycobacterium smegmatis | Descriptor: | 1,2-ETHANEDIOL, Putative acyl-CoA dehydrogenase, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl (2R,3S,4S)-5-[(4aS,10aR)-7,8-dimethyl-2,4-dioxo-1,3,4,4a,5,10a-hexahydrobenzo[g]pteridin-10(2H)-yl]-2,3,4-trihydroxypentyl dihydrogen diphosphate | Authors: | Seattle Structural Genomics Center for Infectious Disease (SSGCID) | Deposit date: | 2010-10-07 | Release date: | 2010-10-20 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
|
|
3P0T
| |
3P32
| |
3R6H
| |
3RD5
| |
3RD7
| |
2DBT
| |
3GVG
| |
3GWC
| |
3H81
| |
3HWK
| |
3HWI
| |