5XIK
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![BU of 5xik by Molmil](/molmil-images/mine/5xik) | Crystal Structure of Toxoplasma gondii Prolyl-tRNA Synthetase (TgPRS) in complex with tetrahydro quinazolinone febrifugine | Descriptor: | 3-[2-oxidanylidene-3-[(2R,3R)-3-oxidanylpiperidin-2-yl]propyl]-5,6,7,8-tetrahydroquinazolin-4-one, CHLORIDE ION, MAGNESIUM ION, ... | Authors: | Jain, V, Manickam, Y, Sharma, A. | Deposit date: | 2017-04-26 | Release date: | 2018-03-07 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Targeting Prolyl-tRNA Synthetase to Accelerate Drug Discovery against Malaria, Leishmaniasis, Toxoplasmosis, Cryptosporidiosis, and Coccidiosis Structure, 25, 2017
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5XIP
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![BU of 5xip by Molmil](/molmil-images/mine/5xip) | Crystal Structure of Eimeria tenella Prolyl-tRNA Synthetase (EtPRS) in complex with Halofuginone | Descriptor: | 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Jain, V, Manickam, Y, Sharma, A. | Deposit date: | 2017-04-26 | Release date: | 2018-03-07 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Targeting Prolyl-tRNA Synthetase to Accelerate Drug Discovery against Malaria, Leishmaniasis, Toxoplasmosis, Cryptosporidiosis, and Coccidiosis Structure, 25, 2017
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2ZVU
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![BU of 2zvu by Molmil](/molmil-images/mine/2zvu) | Crystal structure of rat heme oxygenase-1 in complex with ferrous verdoheme | Descriptor: | 5-OXA-PROTOPORPHYRIN IX CONTAINING FE, FORMIC ACID, Heme oxygenase 1 | Authors: | Sato, H, Sugishima, M, Fukuyama, K, Noguchi, M. | Deposit date: | 2008-11-21 | Release date: | 2009-02-03 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of rat haem oxygenase-1 in complex with ferrous verdohaem: presence of a hydrogen-bond network on the distal side Biochem.J., 419, 2009
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5XIQ
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![BU of 5xiq by Molmil](/molmil-images/mine/5xiq) | Crystal Structure of Toxoplasma gondii Prolyl-tRNA Synthetase (TgPRS) in complex with Halofuginone | Descriptor: | 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Jain, V, Manickam, Y, Sharma, A. | Deposit date: | 2017-04-26 | Release date: | 2018-03-07 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | Targeting Prolyl-tRNA Synthetase to Accelerate Drug Discovery against Malaria, Leishmaniasis, Toxoplasmosis, Cryptosporidiosis, and Coccidiosis Structure, 25, 2017
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5XII
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![BU of 5xii by Molmil](/molmil-images/mine/5xii) | Crystal Structure of Toxoplasma gondii Prolyl-tRNA Synthetase (TgPRS) in complex with inhibitor 6 | Descriptor: | 1,2-ETHANEDIOL, 6-chloranyl-7-fluoranyl-3-[3-[(2R)-3-oxidanylidenepiperidin-2-yl]propyl]quinazolin-4-one, CHLORIDE ION, ... | Authors: | Jain, V, Manickam, Y, Sharma, A. | Deposit date: | 2017-04-26 | Release date: | 2018-03-07 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.17 Å) | Cite: | Targeting Prolyl-tRNA Synthetase to Accelerate Drug Discovery against Malaria, Leishmaniasis, Toxoplasmosis, Cryptosporidiosis, and Coccidiosis Structure, 25, 2017
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3A2P
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![BU of 3a2p by Molmil](/molmil-images/mine/3a2p) | Structure of 6-aminohexanoate cyclic dimer hydrolase | Descriptor: | 6-aminohexanoate-cyclic-dimer hydrolase, GLYCEROL | Authors: | Shibata, N. | Deposit date: | 2009-05-26 | Release date: | 2009-11-03 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | X-ray crystallographic analysis of the 6-aminohexanoate cyclic dimer hydrolase: catalytic mechanism and evolution of an enzyme responsible for nylon-6 byproduct degradation J.Biol.Chem., 285, 2010
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3A4E
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![BU of 3a4e by Molmil](/molmil-images/mine/3a4e) | Crystal structure of Human Transthyretin (E54G) | Descriptor: | GLYCEROL, SULFATE ION, Transthyretin | Authors: | Miyata, M, Sato, T, Nakamura, T, Ikemizu, S, Yamagata, Y, Kai, H. | Deposit date: | 2009-07-06 | Release date: | 2009-12-22 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Role of the glutamic acid 54 residue in transthyretin stability and thyroxine binding Biochemistry, 49, 2010
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2ZXX
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![BU of 2zxx by Molmil](/molmil-images/mine/2zxx) | Crystal structure of Cdt1/geminin complex | Descriptor: | DNA replication factor Cdt1, Geminin | Authors: | Cho, Y, Lee, C, Hong, B.S, Choi, J.M. | Deposit date: | 2009-01-08 | Release date: | 2009-02-17 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural basis for inhibition of the replication licensing factor Cdt1 by geminin Nature, 430, 2004
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3A4D
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![BU of 3a4d by Molmil](/molmil-images/mine/3a4d) | Crystal structure of Human Transthyretin (wild-type) | Descriptor: | GLYCEROL, SULFATE ION, Transthyretin | Authors: | Miyata, M. | Deposit date: | 2009-07-06 | Release date: | 2009-12-22 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Role of the Glutamic Acid 54 Residue in Transthyretin Stability and Thyroxine Binding Biochemistry, 2009
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2EC7
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![BU of 2ec7 by Molmil](/molmil-images/mine/2ec7) | Solution Structure of Human Immunodificiency Virus Type-2 Nucleocapsid Protein | Descriptor: | Gag polyprotein (Pr55Gag), ZINC ION | Authors: | Matsui, T, Kodera, Y, Tanaka, T, Endoh, H, Tanaka, H, Miyauchi, E, Komatsu, H, Kohno, T, Maeda, T. | Deposit date: | 2007-02-10 | Release date: | 2008-02-19 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | The RNA recognition mechanism of human immunodeficiency virus (HIV) type 2 NCp8 is different from that of HIV-1 NCp7 Biochemistry, 48, 2009
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2D7T
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![BU of 2d7t by Molmil](/molmil-images/mine/2d7t) | |
3AW5
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![BU of 3aw5 by Molmil](/molmil-images/mine/3aw5) | Structure of a multicopper oxidase from the hyperthermophilic archaeon Pyrobaculum aerophilum | Descriptor: | ACETATE ION, COPPER (II) ION, CU-O-CU LINKAGE, ... | Authors: | Sakuraba, H, Ohshima, T, Yoneda, K. | Deposit date: | 2011-03-10 | Release date: | 2011-06-08 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of a multicopper oxidase from the hyperthermophilic archaeon Pyrobaculum aerophilum Acta Crystallogr.,Sect.F, 67, 2011
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3AW0
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![BU of 3aw0 by Molmil](/molmil-images/mine/3aw0) | Structure of SARS 3CL protease with peptidic aldehyde inhibitor | Descriptor: | 3C-Like Proteinase, peptide ACE-SER-ALA-VAL-LEU-HIS-H | Authors: | Akaji, K, Konno, H, Mitsui, H, Teruya, K, Hattori, Y, Ozaki, T, Kusunoki, M, Sanjho, A. | Deposit date: | 2011-03-09 | Release date: | 2011-12-14 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure-Based Design, Synthesis, and Evaluation of Peptide-Mimetic SARS 3CL Protease Inhibitors. J.Med.Chem., 54, 2011
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3AW1
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![BU of 3aw1 by Molmil](/molmil-images/mine/3aw1) | Structure of SARS 3CL protease auto-proteolysis resistant mutant in the absent of inhibitor | Descriptor: | 3C-Like Proteinase | Authors: | Akaji, K, Konno, H, Mitsui, H, Teruya, K, Hattori, Y, Ozaki, T, Kusunoki, M, Sanjho, A. | Deposit date: | 2011-03-09 | Release date: | 2011-12-14 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure-Based Design, Synthesis, and Evaluation of Peptide-Mimetic SARS 3CL Protease Inhibitors. J.Med.Chem., 54, 2011
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3ATW
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![BU of 3atw by Molmil](/molmil-images/mine/3atw) | Structure-Based Design, Synthesis, Evaluation of Peptide-mimetic SARS 3CL Protease Inhibitors | Descriptor: | 3C-Like Proteinase, peptide ACE-THR-VAL-ALC-HIS-H | Authors: | Akaji, K, Konno, H, Mitsui, H, Teruya, K, Hattori, Y, Ozaki, T, Kusunoki, M, Sanjho, A. | Deposit date: | 2011-01-20 | Release date: | 2011-12-14 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.36 Å) | Cite: | Structure-Based Design, Synthesis, and Evaluation of Peptide-Mimetic SARS 3CL Protease Inhibitors. J.Med.Chem., 54, 2011
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3AVZ
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![BU of 3avz by Molmil](/molmil-images/mine/3avz) | Structure of SARS 3CL protease with peptidic aldehyde inhibitor containing cyclohexyl side chain | Descriptor: | 3C-Like Proteinase, peptide ACE-SER-ALA-VAL-ALC-HIS-H | Authors: | Akaji, K, Konno, H, Mitsui, H, Teruya, K, Hattori, Y, Ozaki, T, Kusunoki, M, Sanjho, A. | Deposit date: | 2011-03-09 | Release date: | 2011-12-14 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.46 Å) | Cite: | Structure-Based Design, Synthesis, and Evaluation of Peptide-Mimetic SARS 3CL Protease Inhibitors. J.Med.Chem., 54, 2011
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5XRZ
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![BU of 5xrz by Molmil](/molmil-images/mine/5xrz) | Structure of a ssDNA bound to the inner DNA binding site of RAD52 | Descriptor: | DNA repair protein RAD52 homolog, POTASSIUM ION, ssDNA (40-MER) | Authors: | Saotome, M, Saito, K, Yasuda, T, Sugiyama, S, Kurumizaka, H, Kagawa, W. | Deposit date: | 2017-06-11 | Release date: | 2018-04-25 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Structural Basis of Homology-Directed DNA Repair Mediated by RAD52 iScience, 3, 2018
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3AL9
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![BU of 3al9 by Molmil](/molmil-images/mine/3al9) | Mouse Plexin A2 extracellular domain | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Plexin-A2 | Authors: | Nogi, T, Yasui, N, Mihara, E, Takagi, J. | Deposit date: | 2010-07-28 | Release date: | 2010-10-06 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis for semaphorin signalling through the plexin receptor. Nature, 467, 2010
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5XS0
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![BU of 5xs0 by Molmil](/molmil-images/mine/5xs0) | Structure of a ssDNA bound to the outer DNA binding site of RAD52 | Descriptor: | DNA repair protein RAD52 homolog, ssDNA (5'-D(*CP*CP*CP*CP*CP*C)-3'), ssDNA (5'-D(*CP*CP*CP*CP*CP*CP*CP*C)-3'), ... | Authors: | Saotome, M, Saito, K, Yasuda, T, Sugiyama, S, Kurumizaka, H, Kagawa, W. | Deposit date: | 2017-06-11 | Release date: | 2018-04-25 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural Basis of Homology-Directed DNA Repair Mediated by RAD52 iScience, 3, 2018
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5ZT8
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![BU of 5zt8 by Molmil](/molmil-images/mine/5zt8) | SirB from Bacillus subtilis | Descriptor: | Sirohydrochlorin ferrochelatase | Authors: | Fujishiro, T. | Deposit date: | 2018-05-02 | Release date: | 2019-02-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of sirohydrochlorin ferrochelatase SirB: the last of the structures of the class II chelatase family. Dalton Trans, 48, 2019
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3AFC
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![BU of 3afc by Molmil](/molmil-images/mine/3afc) | Mouse Semaphorin 6A extracellular domain | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Semaphorin-6A | Authors: | Yasui, N, Nogi, T, Mihara, E, Takagi, J. | Deposit date: | 2010-02-26 | Release date: | 2010-10-06 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis for semaphorin signalling through the plexin receptor. Nature, 467, 2010
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3AL8
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![BU of 3al8 by Molmil](/molmil-images/mine/3al8) | Plexin A2 / Semaphorin 6A complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Plexin-A2, ... | Authors: | Nogi, T, Yasui, N, Mihara, E, Takagi, J. | Deposit date: | 2010-07-28 | Release date: | 2010-10-06 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Structural basis for semaphorin signalling through the plexin receptor. Nature, 467, 2010
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5ZT7
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![BU of 5zt7 by Molmil](/molmil-images/mine/5zt7) | SirB from Bacillus subtilis with Co2+ | Descriptor: | COBALT (II) ION, Sirohydrochlorin ferrochelatase | Authors: | Fujishiro, T. | Deposit date: | 2018-05-02 | Release date: | 2019-02-27 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.94 Å) | Cite: | Structure of sirohydrochlorin ferrochelatase SirB: the last of the structures of the class II chelatase family. Dalton Trans, 48, 2019
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2CB3
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![BU of 2cb3 by Molmil](/molmil-images/mine/2cb3) | Crystal structure of peptidoglycan recognition protein-LE in complex with tracheal cytotoxin (monomeric diaminopimelic acid-type peptidoglycan) | Descriptor: | GLCNAC(BETA1-4)-MURNAC(1,6-ANHYDRO)-L-ALA-GAMMA-D-GLU-MESO-A2PM-D-ALA, GLYCEROL, PEPTIDOGLYCAN-RECOGNITION PROTEIN-LE | Authors: | Lim, J.-H, Kim, M.-S, Oh, B.-H. | Deposit date: | 2005-12-29 | Release date: | 2006-01-26 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural Basis for Preferential Recognition of Diaminopimelic Acid-Type Peptidoglycan by a Subset of Peptidoglycan Recognition Proteins J.Biol.Chem., 281, 2006
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3A5R
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![BU of 3a5r by Molmil](/molmil-images/mine/3a5r) | Benzalacetone synthase from Rheum palmatum complexed with 4-coumaroyl-primed monoketide intermediate | Descriptor: | 4'-HYDROXYCINNAMIC ACID, Benzalacetone synthase | Authors: | Morita, H, Kato, R, Abe, I, Sugio, S, Kohno, T. | Deposit date: | 2009-08-10 | Release date: | 2010-01-26 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | A structure-based mechanism for benzalacetone synthase from Rheum palmatum Proc.Natl.Acad.Sci.USA, 107, 2010
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