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4LUK
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BU of 4luk by Molmil
The crystal structure of the P132A, Y133G mutant of Pyrococcus furiosus phosphoglucose isomerase in complex with manganese and 5-phospho-D-arabinonate.
Descriptor: 1,2-ETHANEDIOL, 5-PHOSPHOARABINONIC ACID, Glucose-6-phosphate isomerase, ...
Authors:Baker, P.J, Almourfi, F.M.
Deposit date:2013-07-25
Release date:2014-07-30
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.41 Å)
Cite:Correlated mutation analysis as a tool for smart library design to improve protein performance.
To be Published
4LUL
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BU of 4lul by Molmil
The crystal structure of the P132A, Y133D mutant of Pyrococcus furiosus phosphoglucose isomerase in complex with manganese.
Descriptor: Glucose-6-phosphate isomerase, MANGANESE (II) ION
Authors:Baker, P.J, Almourfi, F.M.
Deposit date:2013-07-25
Release date:2014-07-30
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Correlated mutation analysis as a tool for smart library design to improve protein performance.
To be Published
4LTA
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BU of 4lta by Molmil
The crystal structure of the P132R, Y133G mutant of Pyrococcus furiosus phosphoglucose isomerase in complex with manganese and 5-phospho-D-arabinonate.
Descriptor: 1,2-ETHANEDIOL, 5-PHOSPHOARABINONIC ACID, Glucose-6-phosphate isomerase, ...
Authors:Baker, P.J, Almourfi, F.M.
Deposit date:2013-07-23
Release date:2014-07-30
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Correlated mutation analysis as a tool for smart library design to improve protein performance.
To be Published
3KXL
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BU of 3kxl by Molmil
crystal structure of SsGBP mutation variant G235S
Descriptor: GTP-binding protein (HflX), THIOCYANATE ION
Authors:Huang, B, Li, X, Zhang, X.C, Rao, Z.
Deposit date:2009-12-03
Release date:2010-05-26
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Functional study on GTP hydrolysis by the GTP binding protein from Sulfolobus solfataricus, a member of the HflX family.
J.Biochem., 2010
8TL0
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BU of 8tl0 by Molmil
Structure of activated SAVED-CHAT filament
Descriptor: CHAT domain-containing protein, RNA (5'-R(*AP*AP*A)-3')
Authors:Bravo, J.P.K, Taylor, D.W.
Deposit date:2023-07-26
Release date:2024-03-06
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Type III-B CRISPR-Cas cascade of proteolytic cleavages.
Science, 383, 2024
3KXI
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BU of 3kxi by Molmil
crystal structure of SsGBP and GDP complex
Descriptor: GTP-binding protein (HflX), GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Huang, B, Li, X, Zhang, X.C, Rao, Z.
Deposit date:2009-12-03
Release date:2010-05-26
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Functional study on GTP hydrolysis by the GTP binding protein from Sulfolobus solfataricus, a member of the HflX family.
J.Biochem., 2010
3KXK
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BU of 3kxk by Molmil
Crystal structure of SsGBP mutation variant G235P
Descriptor: GTP-binding protein (HflX)
Authors:Huang, B, Li, X, Zhang, X.C, Rao, Z.
Deposit date:2009-12-03
Release date:2010-05-26
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Functional study on GTP hydrolysis by the GTP binding protein from Sulfolobus solfataricus, a member of the HflX family.
J.Biochem., 2010
4TVX
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BU of 4tvx by Molmil
Crystal structure of the E. coli CRISPR RNA-guided surveillance complex, Cascade
Descriptor: CRISPR system Cascade subunit CasA, CRISPR system Cascade subunit CasB, CRISPR system Cascade subunit CasC, ...
Authors:Jackson, R.N, Golden, S.M, Carter, J, Wiedenheft, B.
Deposit date:2014-06-28
Release date:2014-08-13
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.24 Å)
Cite:Structural biology. Crystal structure of the CRISPR RNA-guided surveillance complex from Escherichia coli.
Science, 345, 2014
8HIO
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BU of 8hio by Molmil
Cryo-EM structure of the Cas12m2-crRNA binary complex
Descriptor: Cas12m2, MAGNESIUM ION, RNA (56-MER), ...
Authors:Omura, N.S, Nakagawa, R, Wu, Y.W, Sudfeld, C, Warren, V.R, Hirano, H, Kusakizako, T, Kise, Y, Lebbink, H.G.J, Itoh, Y, Oost, V.D.J, Nureki, O.
Deposit date:2022-11-21
Release date:2023-04-12
Last modified:2023-08-30
Method:ELECTRON MICROSCOPY (3.73 Å)
Cite:Mechanistic and evolutionary insights into a type V-M CRISPR-Cas effector enzyme.
Nat.Struct.Mol.Biol., 30, 2023
8HHM
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BU of 8hhm by Molmil
Cryo-EM structure of the Cas12m2-crRNA-target DNA ternary complex intermediate state
Descriptor: Cas12m2, DNA (36-MER), MAGNESIUM ION, ...
Authors:Omura, N.S, Nakagawa, R, Wu, Y.W, Sudfeld, C, Warren, V.R, Hirano, H, Kusakizako, T, Kise, Y, Lebbink, H.G.J, Itoh, Y, Oost, V.D.J, Nureki, O.
Deposit date:2022-11-16
Release date:2023-04-12
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.08 Å)
Cite:Mechanistic and evolutionary insights into a type V-M CRISPR-Cas effector enzyme.
Nat.Struct.Mol.Biol., 30, 2023
8HHL
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BU of 8hhl by Molmil
Cryo-EM structure of the Cas12m2-crRNA-target DNA full R-loop complex
Descriptor: Cas12m2, MAGNESIUM ION, NTS (36-MER), ...
Authors:Omura, N.S, Nakagawa, R, Wu, Y.W, Sudfeld, C, Warren, V.R, Hirano, H, Kusakizako, T, Kise, Y, Lebbink, H.G.J, Itoh, Y, Oost, V.D.J, Nureki, O.
Deposit date:2022-11-16
Release date:2023-04-12
Last modified:2023-08-30
Method:ELECTRON MICROSCOPY (2.87 Å)
Cite:Mechanistic and evolutionary insights into a type V-M CRISPR-Cas effector enzyme.
Nat.Struct.Mol.Biol., 30, 2023
8H1J
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BU of 8h1j by Molmil
Cryo-EM structure of the TnpB-omegaRNA-target DNA ternary complex
Descriptor: Non-target strand, RNA-guided DNA endonuclease TnpB, Target strand, ...
Authors:Nakagawa, R, Hirano, H, Omura, S, Nureki, O.
Deposit date:2022-10-03
Release date:2023-04-12
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Cryo-EM structure of the transposon-associated TnpB enzyme.
Nature, 616, 2023
3M82
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BU of 3m82 by Molmil
Crystal structure of Acetyl xylan esterase (TM0077) from THERMOTOGA MARITIMA at 2.40 A resolution (PMSF inhibitor complex structure)
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Acetyl xylan esterase, ...
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2010-03-17
Release date:2010-05-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Functional and structural characterization of a thermostable acetyl esterase from Thermotoga maritima.
Proteins, 80, 2012
3M81
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BU of 3m81 by Molmil
Crystal structure of Acetyl xylan esterase (TM0077) from THERMOTOGA MARITIMA at 2.50 A resolution (native apo structure)
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Acetyl xylan esterase, ...
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2010-03-17
Release date:2010-04-21
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Functional and structural characterization of a thermostable acetyl esterase from Thermotoga maritima.
Proteins, 80, 2012
3M83
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BU of 3m83 by Molmil
Crystal structure of Acetyl xylan esterase (TM0077) from THERMOTOGA MARITIMA at 2.12 A resolution (paraoxon inhibitor complex structure)
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Acetyl xylan esterase, ...
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2010-03-17
Release date:2010-05-12
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Functional and structural characterization of a thermostable acetyl esterase from Thermotoga maritima.
Proteins, 80, 2012
1UV6
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BU of 1uv6 by Molmil
X-ray structure of acetylcholine binding protein (AChBP) in complex with carbamylcholine
Descriptor: 2-[(AMINOCARBONYL)OXY]-N,N,N-TRIMETHYLETHANAMINIUM, ACETYLCHOLINE-BINDING PROTEIN
Authors:Celie, P.H.N, Van Rossum-fikkert, S.E, Van Dijk, W.J, Brejc, K, Smit, A.B, Sixma, T.K.
Deposit date:2004-01-15
Release date:2004-03-25
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Nicotine and Carbamylcholine Binding to Nicotinic Acetylcholine Receptors as Studied in Achbp Crystal Structures
Neuron, 41, 2004
1UW6
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BU of 1uw6 by Molmil
X-ray structure of acetylcholine binding protein (AChBP) in complex with nicotine
Descriptor: (S)-3-(1-METHYLPYRROLIDIN-2-YL)PYRIDINE, ACETYLCHOLINE-BINDING PROTEIN
Authors:Celie, P.H.N, Van Rossum-fikkert, S.E, Van Dijk, W.J, Brejc, K, Smit, A.B, Sixma, T.K.
Deposit date:2004-01-30
Release date:2004-03-25
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Nicotine and Carbamylcholine Binding to Nicotinic Acetylcholine Receptors as Studied in Achbp Crystal Structures
Neuron, 41, 2004
1UX2
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BU of 1ux2 by Molmil
X-ray structure of acetylcholine binding protein (AChBP)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETYLCHOLINE BINDING PROTEIN, ...
Authors:Celie, P.H.N, Van Rossum-fikkert, S.E, Van Dijk, W.J, Brejc, K, Smit, A.B, Sixma, T.K.
Deposit date:2004-02-18
Release date:2004-03-25
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Nicotine and Carbamylcholine Binding to Nicotinic Acetylcholine Receptors as Studied in Achbp Crystal Structures
Neuron, 41, 2004
4KPY
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BU of 4kpy by Molmil
DNA binding protein and DNA complex structure
Descriptor: DNA (5'-D(*TP*AP*TP*AP*CP*AP*AP*CP*C)-3'), DNA (5'-D(P*TP*AP*CP*TP*AP*CP*CP*TP*CP*G)-3'), DNA (5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*TP*AP*GP*T)-3'), ...
Authors:Sheng, G, Zhao, H, Wang, J, Rao, Y, Wang, Y.
Deposit date:2013-05-14
Release date:2014-01-29
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.406 Å)
Cite:Structure-based cleavage mechanism of Thermus thermophilus Argonaute DNA guide strand-mediated DNA target cleavage.
Proc.Natl.Acad.Sci.USA, 111, 2014
2CFX
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BU of 2cfx by Molmil
Structure of B.subtilis LrpC
Descriptor: HTH-TYPE TRANSCRIPTIONAL REGULATOR LRPC
Authors:Thaw, P, Rafferty, J.B.
Deposit date:2006-02-24
Release date:2006-03-28
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Insight Into Gene Transcriptional Regulation and Effector Binding by the Lrp/Asnc Family.
Nucleic Acids Res., 34, 2006
3BQB
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BU of 3bqb by Molmil
Hexagonal kristal form of 2-keto-3-deoxyarabinonate dehydratase
Descriptor: MAGNESIUM ION, Putative uncharacterized protein
Authors:Barends, T.M, Brouns, S, Worm, P, Akerboom, J, Turnbull, A, Salmon, L.
Deposit date:2007-12-20
Release date:2008-04-08
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural insight into substrate binding and catalysis of a novel 2-keto-3-deoxy-D-arabinonate dehydratase illustrates common mechanistic features of the FAH superfamily
J.Mol.Biol., 379, 2008
2VY0
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BU of 2vy0 by Molmil
The X-ray structure of endo-beta-1,3-glucanase from Pyrococcus furiosus
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, ...
Authors:Ilari, A, Fiorillo, A.
Deposit date:2008-07-15
Release date:2009-03-24
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Crystal Structure of a Family 16 Endoglucanase from the Hyperthermophile Pyrococcus Furiosus-Structural Basis of Substrate Recognition.
FEBS J., 276, 2009
1CYX
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BU of 1cyx by Molmil
QUINOL OXIDASE (PERIPLASMIC FRAGMENT OF SUBUNIT II WITH ENGINEERED CU-A BINDING SITE)(CYOA)
Descriptor: CYOA, DINUCLEAR COPPER ION
Authors:Wilmanns, M, Lappalainen, P, Kelly, M, Sauer-Eriksson, E, Saraste, M.
Deposit date:1995-08-22
Release date:1996-03-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the membrane-exposed domain from a respiratory quinol oxidase complex with an engineered dinuclear copper center.
Proc.Natl.Acad.Sci.USA, 92, 1995
2H6C
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BU of 2h6c by Molmil
Crystal structure of reduced CprK in absence of any ligand
Descriptor: ChloroPhenol Reduction gene K
Authors:Levy, C, Leys, D.
Deposit date:2006-05-31
Release date:2006-07-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:CprK Crystal Structures Reveal Mechanism for Transcriptional Control of Halorespiration.
J.Biol.Chem., 281, 2006
2H6B
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BU of 2h6b by Molmil
Crystal structure of oxidized CprK in complex with o-chlorophenolacetic acid
Descriptor: (3-CHLORO-4-HYDROXYPHENYL)ACETIC ACID, ChloroPhenol Reduction gene K, SULFATE ION
Authors:Joyce, M.G, Levy, C, Leys, D.
Deposit date:2006-05-31
Release date:2006-07-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:CprK Crystal Structures Reveal Mechanism for Transcriptional Control of Halorespiration.
J.Biol.Chem., 281, 2006

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