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4D2B
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BU of 4d2b by Molmil
Structure of a ligand free POT family peptide transporter
Descriptor: (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, DI-OR TRIPEPTIDE:H+ SYMPORTER, ...
Authors:Lyons, J.A, Parker, J.L, Solcan, N, Brinth, A, Li, D, Shah, S.T.A, Caffrey, M, Newstead, S.
Deposit date:2014-05-09
Release date:2014-06-25
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural Basis for Polyspecificity in the Pot Family of Proton-Coupled Oligopeptide Transporters.
Embo Rep., 15, 2014
4D2C
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BU of 4d2c by Molmil
Structure of a di peptide bound POT family peptide transporter
Descriptor: (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, ALANINE, ...
Authors:Lyons, J.A, Parker, J.L, Solcan, N, Brinth, A, Li, D, Shah, S.T.A, Caffrey, M, Newstead, S.
Deposit date:2014-05-09
Release date:2014-06-25
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:Structural Basis for Polyspecificity in the Pot Family of Proton-Coupled Oligopeptide Transporters.
Embo Rep., 15, 2014
4D2D
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BU of 4d2d by Molmil
Structure of a tri peptide bound POT family peptide transporter
Descriptor: (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, ALANINE-TRIPEPTIDE, ...
Authors:Lyons, J.A, Parker, J.L, Solcan, N, Brinth, A, Li, D, Shah, S.T.A, Caffrey, M, Newstead, S.
Deposit date:2014-05-09
Release date:2014-06-25
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.522 Å)
Cite:Structural Basis for Polyspecificity in the Pot Family of Proton-Coupled Oligopeptide Transporters.
Embo Rep., 15, 2014
1OB9
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BU of 1ob9 by Molmil
Holliday Junction Resolving Enzyme
Descriptor: 1,2-ETHANEDIOL, FORMIC ACID, HOLLIDAY JUNCTION RESOLVASE
Authors:Middleton, C.L, Parker, J.L, Richard, D.J, White, M.F, Bond, C.S.
Deposit date:2003-01-28
Release date:2004-10-15
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Substrate Recognition and Catalysis by the Holliday Junction Resolving Enzyme Hje.
Nucleic Acids Res., 32, 2004
1OB8
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BU of 1ob8 by Molmil
Holliday Junction Resolving Enzyme
Descriptor: 1,2-ETHANEDIOL, HOLLIDAY-JUNCTION RESOLVASE, SULFATE ION
Authors:Middleton, C.L, Parker, J.L, Richard, D.J, White, M.F, Bond, C.S.
Deposit date:2003-01-28
Release date:2004-10-15
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Substrate Recognition and Catalysis by the Holliday Junction Resolving Enzyme Hje.
Nucleic Acids Res., 32, 2004
6EI3
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BU of 6ei3 by Molmil
Crystal structure of auto inhibited POT family peptide transporter
Descriptor: (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, Proton-dependent oligopeptide transporter family protein
Authors:Newstead, S, Brinth, A, Vogeley, L, Caffrey, M.
Deposit date:2017-09-17
Release date:2017-11-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Proton movement and coupling in the POT family of peptide transporters.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6I6H
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BU of 6i6h by Molmil
Crystal structure of the KDEL receptor in the peptide bound state
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, AEKDEL peptide, ER lumen protein-retaining receptor 2
Authors:Braeuer, P, Newstead, S.
Deposit date:2018-11-15
Release date:2019-02-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for pH-dependent retrieval of ER proteins from the Golgi by the KDEL receptor.
Science, 363, 2019
6Y7V
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BU of 6y7v by Molmil
Crystal structure of the KDEL receptor bound to HDEL peptide at pH 6.0
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CARBON DIOXIDE, ER lumen protein-retaining receptor 2, ...
Authors:Braeuer, P, Newstead, S.
Deposit date:2020-03-02
Release date:2021-02-10
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.241 Å)
Cite:A signal capture and proofreading mechanism for the KDEL-receptor explains selectivity and dynamic range in ER retrieval.
Elife, 10, 2021
7ZKZ
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BU of 7zkz by Molmil
Crystal structure of cystinosin from Arabidopsis thaliana bound to two nanobodies
Descriptor: Cystinosin homolog, Llama nanobody, nanobody
Authors:Loebel, M, Newstead, S.
Deposit date:2022-04-13
Release date:2022-08-31
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.329 Å)
Cite:Structural basis for proton coupled cystine transport by cystinosin.
Nat Commun, 13, 2022
7ZK1
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BU of 7zk1 by Molmil
Crystal structure of cystinosin from Arabidopsis thaliana bound to sybody and nanobody
Descriptor: Cystinosin homolog, Llama derived nanobody, Synthetic nanobody (Sybody)
Authors:Loebel, M, Newstead, S, Omari, K.E.
Deposit date:2022-04-12
Release date:2022-08-31
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural basis for proton coupled cystine transport by cystinosin.
Nat Commun, 13, 2022
4TKD
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BU of 4tkd by Molmil
Sulfolobus solfataricus HJC mutants
Descriptor: Holliday junction resolvase Hjc
Authors:Bond, C.S.
Deposit date:2014-05-26
Release date:2015-08-12
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Crystal Unengineering: Reducing the Crystallisability of Sulfolobus solfataricus Hjc
Aust.J.Chem., 67, 2014
4TKK
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BU of 4tkk by Molmil
Sulfolobus solfataricus HJC mutants
Descriptor: Holliday junction resolvase Hjc
Authors:Bond, C.S.
Deposit date:2014-05-27
Release date:2015-08-12
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Unengineering: Reducing the Crystallisability of Sulfolobus solfataricus Hjc
Aust.J.Chem., 67, 2014
6I6B
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BU of 6i6b by Molmil
Crystal structure of the KDEL receptor in the peptide free state.
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, ER lumen protein-retaining receptor 2
Authors:Braeuer, P, Newstead, S.
Deposit date:2018-11-15
Release date:2019-02-27
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Structural basis for pH-dependent retrieval of ER proteins from the Golgi by the KDEL receptor.
Science, 363, 2019
6I6J
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BU of 6i6j by Molmil
Crystal structure of the KDEL receptor bound to synthetic nanobody.
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, ER lumen protein-retaining receptor 2, Sybody
Authors:Braeuer, P, Newstead, S.
Deposit date:2018-11-15
Release date:2019-02-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Structural basis for pH-dependent retrieval of ER proteins from the Golgi by the KDEL receptor.
Science, 363, 2019
5OQT
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BU of 5oqt by Molmil
Crystal structure of a bacterial cationic amino acid transporter (CAT) homologue
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, ACETATE ION, ALANINE, ...
Authors:Jungnickel, K.E.J, Newstead, S.
Deposit date:2017-08-14
Release date:2018-02-14
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:Structural basis for amino acid transport by the CAT family of SLC7 transporters.
Nat Commun, 9, 2018
6F34
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BU of 6f34 by Molmil
Crystal structure of a bacterial cationic amino acid transporter (CAT) homologue bound to Arginine.
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, ARGININE, Amino acid transporter, ...
Authors:Jungnickel, K.E.J, Newstead, S.
Deposit date:2017-11-27
Release date:2018-02-14
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.13 Å)
Cite:Structural basis for amino acid transport by the CAT family of SLC7 transporters.
Nat Commun, 9, 2018
5A9H
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BU of 5a9h by Molmil
Crystal structure of the extracellular domain of PepT2
Descriptor: ACETATE ION, CESIUM ION, GLYCEROL, ...
Authors:Beale, J.H, Newstead, S.
Deposit date:2015-07-21
Release date:2015-09-09
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Crystal Structures of the Extracellular Domain from Pept1 and Pept2 Provide Novel Insights Into Mammalian Peptide Transport
Structure, 23, 2015
5A9I
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BU of 5a9i by Molmil
Crystal structure of the extracellular domain of PepT2
Descriptor: CITRIC ACID, GLYCEROL, SOLUTE CARRIER FAMILY 15 MEMBER 2
Authors:Beale, J.H, Newstead, S.
Deposit date:2015-07-21
Release date:2015-09-09
Last modified:2019-10-09
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:Crystal Structures of the Extracellular Domain from Pept1 and Pept2 Provide Novel Insights Into Mammalian Peptide Transport
Structure, 23, 2015
5A9D
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BU of 5a9d by Molmil
Crystal structure of the extracellular domain of PepT1
Descriptor: GLYCEROL, SOLUTE CARRIER FAMILY 15 MEMBER 1
Authors:Beale, J.H, Bird, L.E, Owens, R.J, Newstead, S.
Deposit date:2015-07-20
Release date:2015-09-09
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structures of the Extracellular Domain from Pept1 and Pept2 Provide Novel Insights Into Mammalian Peptide Transport
Structure, 23, 2015
3VS2
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BU of 3vs2 by Molmil
Crystal structure of HCK complexed with a pyrrolo-pyrimidine inhibitor 7-[cis-4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Descriptor: 7-[cis-4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine, CALCIUM ION, CHLORIDE ION, ...
Authors:Kuratani, M, Tomabechi, Y, Niwa, H, Parker, J.L, Handa, N, Yokoyama, S.
Deposit date:2012-04-21
Release date:2013-05-01
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.609 Å)
Cite:A Pyrrolo-Pyrimidine Derivative Targets Human Primary AML Stem Cells in Vivo
Sci Transl Med, 5, 2013
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