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3P5B
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BU of 3p5b by Molmil
The structure of the LDLR/PCSK9 complex reveals the receptor in an extended conformation
Descriptor: CALCIUM ION, Low density lipoprotein receptor variant, Proprotein convertase subtilisin/kexin type 9
Authors:Lo Surdo, P, Bottomley, M.J, Calzetta, A, Settembre, E.C, Cirillo, A, Pandit, S, Ni, Y, Hubbard, B, Sitlani, A, Carfi, A.
Deposit date:2010-10-08
Release date:2011-10-26
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Mechanistic implications for LDL receptor degradation from the PCSK9/LDLR structure at neutral pH.
Embo Rep., 12, 2011
3P5C
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BU of 3p5c by Molmil
The structure of the LDLR/PCSK9 complex reveals the receptor in an extended conformation
Descriptor: CALCIUM ION, Low density lipoprotein receptor variant, Proprotein convertase subtilisin/kexin type 9
Authors:Lo Surdo, P, Bottomley, M.J, Calzetta, A, Settembre, E.C, Cirillo, A, Pandit, S, Ni, Y, Hubbard, B, Sitlani, A, Carfi, A.
Deposit date:2010-10-08
Release date:2011-10-26
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Mechanistic implications for LDL receptor degradation from the PCSK9/LDLR structure at neutral pH.
Embo Rep., 12, 2011
3SN7
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BU of 3sn7 by Molmil
Highly Potent, Selective, and Orally Active Phosphodiestarase 10A Inhibitors
Descriptor: 8-fluoro-6-methoxy-3,4-dimethyl-1-(3-methylpyridin-4-yl)imidazo[1,5-a]quinoxaline, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Parris, K.D.
Deposit date:2011-06-28
Release date:2011-10-26
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Highly Potent, Selective, and Orally Active Phosphodiesterase 10A Inhibitors.
J.Med.Chem., 54, 2011
7V97
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BU of 7v97 by Molmil
Arsenic-bound p53 DNA-binding domain mutant V272M
Descriptor: ARSENIC, Cellular tumor antigen p53, ZINC ION
Authors:Lu, M, Xing, Y.F, Wang, Z.Y, Ni, Y, Song, H.X.
Deposit date:2021-08-24
Release date:2022-08-31
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Diverse rescue potencies of p53 mutations to ATO are predetermined by intrinsic mutational properties.
Sci Transl Med, 15, 2023
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