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Crystal Structure Analysis of the RNA Dodecamer CGC-NF2-AAUUGGCG, with an Incorporated 2,4-Difluorotoluyl Residue (NF2)
Descriptor:	RNA (5'-R(CPGPCP(NF2)PAPAPUPUPGPGPCPG)-3')
Authors:	Li, F, Pallan, P.S.
Deposit date:	2007-05-25
Release date:	2007-10-30
Last modified:	2024-04-03
Method:	X-RAY DIFFRACTION (1.1 Å)
Cite:	Crystal structure, stability and in vitro RNAi activity of oligoribonucleotides containing the ribo-difluorotoluyl nucleotide: insights into substrate requirements by the human RISC Ago2 enzyme. Nucleic Acids Res., 35, 2007

RNA dodecamer containing a GNA A residue
Descriptor:	Chains: A,B,C,D
Authors:	Harp, J.M, Wawrzak, Z, Egli, M.
Deposit date:	2021-02-09
Release date:	2021-12-22
Last modified:	2024-05-22
Method:	X-RAY DIFFRACTION (1.78 Å)
Cite:	Overcoming GNA/RNA base-pairing limitations using isonucleotides improves the pharmacodynamic activity of ESC+ GalNAc-siRNAs. Nucleic Acids Res., 49, 2021

2'Fluoro modified RNA octamer fA2U2
Descriptor:	2'Fluoro modified RNA 8-MER, MAGNESIUM ION, STRONTIUM ION
Authors:	Manoharan, M, Akinc, A, Pandey, R.K, Qin, J, Hadwiger, P, John, M, Mills, K, Charisse, K, Maier, M.A, Nechev, L, Greene, E.M, Pallan, P.S, Rozners, E, Rajeev, K.G, Egli, M.
Deposit date:	2010-10-06
Release date:	2011-01-05
Last modified:	2024-02-21
Method:	X-RAY DIFFRACTION (1.2 Å)
Cite:	Unexpected origins of the enhanced pairing affinity of 2'-fluoro-modified RNA. Nucleic Acids Res., 39, 2011