5MSN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5msn by Molmil](/molmil-images/mine/5msn) | Structure of the Dcc1 Protein | Descriptor: | DCC1 protein | Authors: | Wade, B.O, Singleton, M.R. | Deposit date: | 2017-01-05 | Release date: | 2017-02-15 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.002 Å) | Cite: | Structural studies of RFC(C)(tf18) reveal a novel chromatin recruitment role for Dcc1. EMBO Rep., 18, 2017
|
|
5MSM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5msm by Molmil](/molmil-images/mine/5msm) | Structure of the Dcc1-Ctf8-Ctf18C Trimer | Descriptor: | Chromosome transmission fidelity protein 18, Chromosome transmission fidelity protein 8, Sister chromatid cohesion protein DCC1 | Authors: | Wade, B.O, Singleton, M.R. | Deposit date: | 2017-01-05 | Release date: | 2017-02-15 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Structural studies of RFC(C)(tf18) reveal a novel chromatin recruitment role for Dcc1. EMBO Rep., 18, 2017
|
|
4N6E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4n6e by Molmil](/molmil-images/mine/4n6e) | Crystal structure of Amycolatopsis orientalis BexX/CysO complex | Descriptor: | Putative thiosugar synthase, SULFATE ION, ThiS/MoaD family protein | Authors: | Zhang, X, Zhang, Y, Kinsland, C, Sasaki, E, Sun, H.G, Lu, M.J, Liu, T, Ou, A, Li, J, Chen, Y, Liu, H, Ealick, S.E. | Deposit date: | 2013-10-11 | Release date: | 2014-05-14 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Co-opting sulphur-carrier proteins from primary metabolic pathways for 2-thiosugar biosynthesis. Nature, 509, 2014
|
|
4N6F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4n6f by Molmil](/molmil-images/mine/4n6f) | Crystal structure of Amycolatopsis orientalis BexX complexed with G6P | Descriptor: | CALCIUM ION, FRUCTOSE -6-PHOSPHATE, Putative thiosugar synthase | Authors: | Zhang, X, Zhang, Y, Kinsland, C, Sasaki, E, Sun, H.G, Lu, M.J, Liu, T, Ou, A, Li, J, Chen, Y, Liu, H, Ealick, S.E. | Deposit date: | 2013-10-11 | Release date: | 2014-05-14 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Co-opting sulphur-carrier proteins from primary metabolic pathways for 2-thiosugar biosynthesis. Nature, 509, 2014
|
|
4PNE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4pne by Molmil](/molmil-images/mine/4pne) | Crystal Structure of the [4+2]-Cyclase SpnF | Descriptor: | MALONATE ION, Methyltransferase-like protein, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Fage, C.D, Isiorho, E.A, Liu, Y.-N, Liu, H.-W, Keatinge-Clay, A.T. | Deposit date: | 2014-05-23 | Release date: | 2015-02-18 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | The structure of SpnF, a standalone enzyme that catalyzes [4 + 2] cycloaddition. Nat.Chem.Biol., 11, 2015
|
|
6NKO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6nko by Molmil](/molmil-images/mine/6nko) | Crystal structure of ForH | Descriptor: | ForH | Authors: | Zheng, J, Irani, S, Zhang, Y. | Deposit date: | 2019-01-07 | Release date: | 2019-04-17 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.403 Å) | Cite: | Identification of the Formycin A Biosynthetic Gene Cluster from Streptomyces kaniharaensis Illustrates the Interplay between Biological Pyrazolopyrimidine Formation and de Novo Purine Biosynthesis. J. Am. Chem. Soc., 141, 2019
|
|
1ORR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1orr by Molmil](/molmil-images/mine/1orr) | |
4J1X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4j1x by Molmil](/molmil-images/mine/4j1x) | |
4J1W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4j1w by Molmil](/molmil-images/mine/4j1w) | |
4LEI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4lei by Molmil](/molmil-images/mine/4lei) | |
7V6H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7v6h by Molmil](/molmil-images/mine/7v6h) | Crystal Structure of the SpnL | Descriptor: | Cyclopropane fatty-acyl-phospholipid synthase-like methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Wu, H.-H, Ko, T.-P, Liu, H.-W, Tsai, M.-D. | Deposit date: | 2021-08-20 | Release date: | 2021-12-29 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (3.054 Å) | Cite: | Evidence for an Enzyme-Catalyzed Rauhut-Currier Reaction during the Biosynthesis of Spinosyn A. J.Am.Chem.Soc., 143, 2021
|
|
7SCP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7scp by Molmil](/molmil-images/mine/7scp) | The crystal structure of ScoE in complex with intermediate | Descriptor: | (3R)-3-(oxaloamino)butanoic acid, 1,2-ETHANEDIOL, FE (II) ION, ... | Authors: | Cha, L, Chen, J, Zhou, J, Chang, W. | Deposit date: | 2021-09-28 | Release date: | 2022-03-23 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Deciphering the Reaction Pathway of Mononuclear Iron Enzyme-Catalyzed N-C Triple Bond Formation in Isocyanide Lipopeptide and Polyketide Biosynthesis Acs Catalysis, 12, 2022
|
|
2JVN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2jvn by Molmil](/molmil-images/mine/2jvn) | Domain C of human PARP-1 | Descriptor: | Poly [ADP-ribose] polymerase 1, ZINC ION | Authors: | Hoffman, D, Tao, Z, Liu, H. | Deposit date: | 2007-09-24 | Release date: | 2008-05-13 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Domain C of human poly(ADP-ribose) polymerase-1 is important for enzyme activity and contains a novel zinc-ribbon motif. Biochemistry, 47, 2008
|
|
3UYK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3uyk by Molmil](/molmil-images/mine/3uyk) | Spinosyn Rhamnosyltransferase SpnG complexed with spinosyn aglycone | Descriptor: | (2R,3aS,5aR,5bS,9S,13S,14R,16aS,16bR)-9-ethyl-2,13-dihydroxy-14-methyl-2,3,3a,5a,5b,6,9,10,11,12,13,14,16a,16b-tetradecahydro-1H-as-indaceno[3,2-d]oxacyclododecine-7,15-dione, MAGNESIUM ION, NDP-rhamnosyltransferase, ... | Authors: | Isiorho, E.A, Liu, H.-W, Keatinge-Clay, A.T. | Deposit date: | 2011-12-06 | Release date: | 2012-02-15 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural Studies of the Spinosyn Rhamnosyltransferase, SpnG. Biochemistry, 51, 2012
|
|
3UYL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3uyl by Molmil](/molmil-images/mine/3uyl) | Spinosyn Rhamnosyltransferase SpnG complexed with thymidine diphosphate | Descriptor: | MAGNESIUM ION, NDP-rhamnosyltransferase, THYMIDINE-5'-DIPHOSPHATE, ... | Authors: | Isiorho, E.A, Liu, H.-W, Keatinge-Clay, A.T. | Deposit date: | 2011-12-06 | Release date: | 2012-02-15 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural Studies of the Spinosyn Rhamnosyltransferase, SpnG. Biochemistry, 51, 2012
|
|
3TSA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3tsa by Molmil](/molmil-images/mine/3tsa) | Spinosyn Rhamnosyltransferase SpnG | Descriptor: | MAGNESIUM ION, NDP-rhamnosyltransferase, alpha-D-glucopyranose | Authors: | Isiorho, E.A, Liu, H.-W, Keatinge-Clay, A.T. | Deposit date: | 2011-09-12 | Release date: | 2012-02-15 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural Studies of the Spinosyn Rhamnosyltransferase, SpnG. Biochemistry, 51, 2012
|
|
3SCH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3sch by Molmil](/molmil-images/mine/3sch) | Co(II)-HppE with R-HPP | Descriptor: | COBALT (II) ION, Epoxidase, [(2R)-2-hydroxypropyl]phosphonic acid | Authors: | Drennan, C.L. | Deposit date: | 2011-06-07 | Release date: | 2011-07-06 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis of regiospecificity of a mononuclear iron enzyme in antibiotic fosfomycin biosynthesis. J.Am.Chem.Soc., 133, 2011
|
|
7VOC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7voc by Molmil](/molmil-images/mine/7voc) | The crystal structure of a Radical SAM Enzyme BlsE involved in the Biosynthesis of Blasticidin S | Descriptor: | (2~{S},3~{S},4~{S},5~{R},6~{R})-6-(4-azanyl-2-oxidanylidene-pyrimidin-1-yl)-3,4,5-tris(oxidanyl)oxane-2-carboxylic acid, Cytosylglucuronate decarboxylase, GLYCEROL, ... | Authors: | Hou, X.L, Zhou, J.H. | Deposit date: | 2021-10-13 | Release date: | 2022-05-04 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.62005424 Å) | Cite: | Radical S -Adenosyl Methionine Enzyme BlsE Catalyzes a Radical-Mediated 1,2-Diol Dehydration during the Biosynthesis of Blasticidin S. J.Am.Chem.Soc., 144, 2022
|
|
7VOB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7vob by Molmil](/molmil-images/mine/7vob) | |
5UL4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ul4 by Molmil](/molmil-images/mine/5ul4) | |
5Z8A
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5z8a by Molmil](/molmil-images/mine/5z8a) | Crystal structure of GenB1 from Micromonospora echinospora in complex with JI-20A and PLP (external aldimine) | Descriptor: | (2~{R},3~{R},4~{R},5~{R})-2-[(1~{S},2~{S},3~{R},4~{S},6~{R})-3-[(2~{R},3~{R},4~{R},5~{S},6~{R})-6-(aminomethyl)-3-azany l-4,5-bis(oxidanyl)oxan-2-yl]oxy-4,6-bis(azanyl)-2-oxidanyl-cyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol, C-6' aminotransferase, PYRIDOXAL-5'-PHOSPHATE | Authors: | Hong, S.K, Cha, S.S. | Deposit date: | 2018-01-31 | Release date: | 2019-01-16 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.398 Å) | Cite: | Complete reconstitution of the diverse pathways of gentamicin B biosynthesis. Nat. Chem. Biol., 15, 2019
|
|
5Z83
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5z83 by Molmil](/molmil-images/mine/5z83) | |
5Z8K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5z8k by Molmil](/molmil-images/mine/5z8k) | Crystal structure of an aminotransferase in complex with product-1 | Descriptor: | (1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl 2,6-diamino-2,6-dideoxy-alpha-D-glucopyranoside, C-6' aminotransferase, PYRIDOXAL-5'-PHOSPHATE | Authors: | Hong, S.K, Cha, S.S. | Deposit date: | 2018-01-31 | Release date: | 2019-01-16 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.759 Å) | Cite: | Complete reconstitution of the diverse pathways of gentamicin B biosynthesis. Nat. Chem. Biol., 15, 2019
|
|
3SCF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3scf by Molmil](/molmil-images/mine/3scf) | Fe(II)-HppE with S-HPP and NO | Descriptor: | (S)-2-HYDROXYPROPYLPHOSPHONIC ACID, Epoxidase, FE (II) ION, ... | Authors: | Drennan, C.L. | Deposit date: | 2011-06-07 | Release date: | 2011-07-06 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Structural basis of regiospecificity of a mononuclear iron enzyme in antibiotic fosfomycin biosynthesis. J.Am.Chem.Soc., 133, 2011
|
|
3SCG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3scg by Molmil](/molmil-images/mine/3scg) | Fe(II)-HppE with R-HPP | Descriptor: | Epoxidase, FE (II) ION, [(2R)-2-hydroxypropyl]phosphonic acid | Authors: | Drennan, C.L. | Deposit date: | 2011-06-07 | Release date: | 2011-07-06 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural basis of regiospecificity of a mononuclear iron enzyme in antibiotic fosfomycin biosynthesis. J.Am.Chem.Soc., 133, 2011
|
|