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6UH6
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BU of 6uh6 by Molmil
EV-A71 strain 11316 complexed with MADAL compound 22
Descriptor: SPHINGOSINE, VP1, VP2, ...
Authors:Lee, H, Hafenstein, S.
Deposit date:2019-09-26
Release date:2019-12-18
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (2.98 Å)
Cite:Scaffold Simplification Strategy Leads to a Novel Generation of Dual Human Immunodeficiency Virus and Enterovirus-A71 Entry Inhibitors.
J.Med.Chem., 63, 2020
6UH1
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BU of 6uh1 by Molmil
Structure of the EVA71 strain 11316 capsid
Descriptor: SPHINGOSINE, VP1, VP2, ...
Authors:Lee, H, Hafenstein, S.
Deposit date:2019-09-26
Release date:2019-12-18
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.04 Å)
Cite:Scaffold Simplification Strategy Leads to a Novel Generation of Dual Human Immunodeficiency Virus and Enterovirus-A71 Entry Inhibitors.
J.Med.Chem., 63, 2020
5LDD
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BU of 5ldd by Molmil
Crystal structure of the heterodimeric GEF Mon1-Ccz1 in complex with Ypt7
Descriptor: Ccz1, Mon1, Rab small monomeric GTPase-like protein, ...
Authors:Kiontke, S, Kuemmel, D.
Deposit date:2016-06-24
Release date:2017-01-18
Last modified:2018-03-14
Method:X-RAY DIFFRACTION (2.496 Å)
Cite:Architecture and mechanism of the late endosomal Rab7-like Ypt7 guanine nucleotide exchange factor complex Mon1-Ccz1.
Nat Commun, 8, 2017
3V42
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BU of 3v42 by Molmil
Crystal structure of renal tumor suppressor protein, folliculin
Descriptor: Folliculin
Authors:Nookala, R.K, Chirgadze, D.Y, Blundell, T.L.
Deposit date:2011-12-14
Release date:2012-08-15
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of folliculin reveals a hidDENN function in genetically inherited renal cancer.
Open Biol, 2, 2012
8QX8
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BU of 8qx8 by Molmil
Endosomal membrane tethering complex CORVET
Descriptor: E3 ubiquitin-protein ligase PEP5, Vacuolar membrane protein PEP3, Vacuolar protein sorting-associated protein 16, ...
Authors:Shvarev, D, Ungermann, C, Moeller, A.
Deposit date:2023-10-23
Release date:2024-07-03
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structure of the endosomal CORVET tethering complex.
Nat Commun, 15, 2024
6GZV
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BU of 6gzv by Molmil
Identification of a druggable VP1-VP3 interprotomer pocket in the capsid of enteroviruses
Descriptor: 4-[[4-[1,3-bis(oxidanylidene)isoindol-2-yl]phenyl]sulfonylamino]benzoic acid, Capsid protein VP1, Capsid protein VP2, ...
Authors:Geraets, J.A, Flatt, J.W, Domanska, A, Butcher, S.J.
Deposit date:2018-07-05
Release date:2019-06-05
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4 Å)
Cite:A novel druggable interprotomer pocket in the capsid of rhino- and enteroviruses.
Plos Biol., 17, 2019
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