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Crystal structure of the PDE4D catalytic domain in complex with GEBR-42a
Descriptor:	1,2-ETHANEDIOL, 3-[(~{E})-1-(3-cyclopentyloxy-4-methoxy-phenyl)ethylideneamino]oxy-1-morpholin-4-yl-propan-1-one, MAGNESIUM ION, ...
Authors:	Torretta, A, Abbate, S, Parisini, E.
Deposit date:	2020-12-14
Release date:	2021-06-30
Last modified:	2024-01-31
Method:	X-RAY DIFFRACTION (1.5 Å)
Cite:	Design, synthesis, biological evaluation and structural characterization of novel GEBR library PDE4D inhibitors. Eur.J.Med.Chem., 223, 2021

Neutralizing antibody mAb#8 in complex with the Epitope II of HCV E2 envelope protein
Descriptor:	E2 envelop protein, Fab heavy chain, Fab light chain
Authors:	Deng, L, Zhang, P.
Deposit date:	2012-11-15
Release date:	2013-05-01
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (2.85 Å)
Cite:	Structural evidence for a bifurcated mode of action in the antibody-mediated neutralization of hepatitis C virus. Proc.Natl.Acad.Sci.USA, 110, 2013

Crystal structure of non-neutralizing antibody in complex with Epitope II of HCV E2
Descriptor:	Envelope glycoprotein E2, mAb 12 heavy chain, mAb 12 light chain
Authors:	Deng, L, Zhang, P.
Deposit date:	2014-04-02
Release date:	2014-07-09
Last modified:	2014-08-06
Method:	X-RAY DIFFRACTION (2.9 Å)
Cite:	Discrete conformations of epitope II on the hepatitis C virus E2 protein for antibody-mediated neutralization and nonneutralization. Proc.Natl.Acad.Sci.USA, 111, 2014

Structure of an AP Endonuclease from Archaeoglobus fulgidus
Descriptor:	5'-D(CPGPGPCPTPAPCPCPGPCP)-3', 5'-D(GPCPGPGPTPAPGPCPCPGP)-3', EXODEOXYRIBONUCLEASE III
Authors:	Kuettner, E.B, Schmiedel, R, Greiner-Stoffele, T, Strater, N.
Deposit date:	2008-02-11
Release date:	2008-12-09
Last modified:	2023-12-13
Method:	X-RAY DIFFRACTION (1.7 Å)
Cite:	Structure and Function of the Abasic Site Specificity Pocket of an Ap Endonuclease from Archaeoglobus Fulgidus. DNA Repair, 8, 2009