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1C4E
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BU of 1c4e by Molmil
GURMARIN FROM GYMNEMA SYLVESTRE
Descriptor: PROTEIN (GURMARIN)
Authors:Fletcher, J.I, Dingley, A.J, King, G.F.
Deposit date:1999-07-27
Release date:1999-08-27
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:High-resolution solution structure of gurmarin, a sweet-taste-suppressing plant polypeptide.
Eur.J.Biochem., 264, 1999
1B8W
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BU of 1b8w by Molmil
DEFENSIN-LIKE PEPTIDE 1
Descriptor: PROTEIN (DEFENSIN-LIKE PEPTIDE 1)
Authors:Torres, A.M, Wang, X, Fletcher, J.I, Alewood, D, Alewood, P.F, Smith, R, Simpson, R.J, Nicholson, G.M, Sutherland, S.K, Gallagher, C.H, King, G.F, Kuchel, P.W.
Deposit date:1999-02-02
Release date:1999-09-15
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution structure of a defensin-like peptide from platypus venom.
Biochem.J., 341, 1999
1AXH
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BU of 1axh by Molmil
ATRACOTOXIN-HVI FROM HADRONYCHE VERSUTA (AUSTRALIAN FUNNEL-WEB SPIDER, NMR, 20 STRUCTURES
Descriptor: ATRACOTOXIN-HVI
Authors:Fletcher, J.I, O'Donoghue, S.I, Nilges, M, King, G.F.
Deposit date:1996-11-04
Release date:1997-11-12
Last modified:2021-02-03
Method:SOLUTION NMR
Cite:The structure of a novel insecticidal neurotoxin, omega-atracotoxin-HV1, from the venom of an Australian funnel web spider.
Nat.Struct.Biol., 4, 1997
1U3O
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BU of 1u3o by Molmil
Solution structure of rat Kalirin N-terminal SH3 domain
Descriptor: Huntingtin-associated protein-interacting protein
Authors:Schiller, M.R, Chakrabarti, K, King, G.F, Schiller, N.I, Eipper, B.A, Maciejewski, M.W.
Deposit date:2004-07-22
Release date:2005-07-26
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Regulation of RhoGEF Activity by Intramolecular and Intermolecular SH3 Domain Interactions.
J.Biol.Chem., 281, 2006
2ALJ
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BU of 2alj by Molmil
Structure of the cis confomer of the major extracytoplasmic domain of the bacterial cell division protein divib from geobacillus stearothermophilus
Descriptor: cell-division initiation protein
Authors:Robson, S.A, King, G.F.
Deposit date:2005-08-05
Release date:2006-04-11
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Domain architecture and structure of the bacterial cell division protein DivIB
Proc.Natl.Acad.Sci.Usa, 103, 2006
1VTX
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BU of 1vtx by Molmil
DELTA-ATRACOTOXIN-HV1 (VERSUTOXIN) FROM HADRONYCHE VERSUTA, NMR, 20 STRUCTURES
Descriptor: DELTA-ATRACOTOXIN-HV1
Authors:Fletcher, J.I, Chapman, B.E, King, G.F.
Deposit date:1997-03-13
Release date:1998-01-28
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:The structure of versutoxin (delta-atracotoxin-Hv1) provides insights into the binding of site 3 neurotoxins to the voltage-gated sodium channel.
Structure, 5, 1997
6A90
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BU of 6a90 by Molmil
Complex of voltage-gated sodium channel NavPaS from American cockroach Periplaneta americana and Dc1a
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Mu-diguetoxin-Dc1a, ...
Authors:Shen, H.Z, li, Z.Q, Jiang, Y, Pan, X.J, Wu, J.P, Cristofori-Armstrong, B, Smith, J.J, Chin, Y.K.Y, Lei, J.L, Zhou, Q, King, G.F, Yan, N.
Deposit date:2018-07-11
Release date:2018-08-08
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structural basis for the modulation of voltage-gated sodium channels by animal toxins.
Science, 362, 2018
6A91
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Complex of voltage-gated sodium channel NavPaS from American cockroach Periplaneta americana bound with saxitoxin and Dc1a
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Shen, H.Z, li, Z.Q, Jiang, Y, Pan, X.J, Wu, J.P, Cristofori-Armstrong, B, Smith, J.J, Chin, Y.K.Y, Lei, J.L, Zhou, Q, King, G.F, Yan, N.
Deposit date:2018-07-11
Release date:2018-08-08
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural basis for the modulation of voltage-gated sodium channels by animal toxins.
Science, 362, 2018
6A95
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BU of 6a95 by Molmil
Complex of voltage-gated sodium channel NavPaS from American cockroach Periplaneta americana bound with tetrodotoxin and Dc1a
Descriptor: (1R,5R,6R,7R,9S,11S,12S,13S,14S)-3-amino-14-(hydroxymethyl)-8,10-dioxa-2,4-diazatetracyclo[7.3.1.1~7,11~.0~1,6~]tetradec-3-ene-5,9,12,13,14-pentol (non-preferred name), 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Shen, H.Z, li, Z.Q, Jiang, Y, Pan, X.J, Wu, J.P, Cristofori-Armstrong, B, Smith, J.J, Chin, Y.K.Y, Lei, J.L, Zhou, Q, King, G.F, Yan, N.
Deposit date:2018-07-11
Release date:2018-08-08
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structural basis for the modulation of voltage-gated sodium channels by animal toxins.
Science, 362, 2018
4MN5
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BU of 4mn5 by Molmil
Crystal structure of PAS domain of S. aureus YycG
Descriptor: Sensor protein kinase WalK, ZINC ION
Authors:Shaikh, N, Hvorup, R, Winnen, B, Collins, B.M, King, G.F.
Deposit date:2013-09-10
Release date:2014-09-10
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of PAS domain of S. aureus YycG
To be Published
4MN6
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BU of 4mn6 by Molmil
Crystal structure of truncated PAS domain from S. aureus YycG
Descriptor: Sensor protein kinase WalK, ZINC ION
Authors:Shaikh, N, Hvorup, R, Winnen, B, Collins, B.M, King, G.F.
Deposit date:2013-09-10
Release date:2014-09-10
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of PAS domain of S. aureus YycG
To be Published
2MUB
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BU of 2mub by Molmil
Solution structure of the analgesic sea anemone peptide APETx2
Descriptor: Toxin APETx2
Authors:Mobli, M, King, G.F, Rosengren, K.J, Jensen, J.E.
Deposit date:2014-09-07
Release date:2014-12-24
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Understanding the Molecular Basis of Toxin Promiscuity: The Analgesic Sea Anemone Peptide APETx2 Interacts with Acid-Sensing Ion Channel 3 and hERG Channels via Overlapping Pharmacophores.
J.Med.Chem., 57, 2014
2MUN
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BU of 2mun by Molmil
Solution structure of mu-SLPTX3-Ssm6a
Descriptor: Mu-scoloptoxin-Ssm6a
Authors:Undheim, E.A.B, King, G.F, Mobli, M.
Deposit date:2014-09-13
Release date:2015-06-24
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Weaponization of a Hormone: Convergent Recruitment of Hyperglycemic Hormone into the Venom of Arthropod Predators.
Structure, 23, 2015
6V6T
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BU of 6v6t by Molmil
Solution structure of delta-theraphotoxin-Hm1b from Heteroscodra maculata
Descriptor: Delta-theraphotoxin-Hm1b
Authors:Chin, Y.K.Y, Chow, C.Y, King, G.F.
Deposit date:2019-12-05
Release date:2020-05-13
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:A selective Na V 1.1 activator with potential for treatment of Dravet syndrome epilepsy.
Biochem Pharmacol, 181, 2020
2L0W
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BU of 2l0w by Molmil
Solution NMR structure of the N-terminal PAS domain of HERG potassium channel
Descriptor: Potassium voltage-gated channel, subfamily H (Eag-related), member 2, ...
Authors:Ng, C.A, Hunter, M.J, Mobli, M, King, G.F, Kuchel, P.W, Vandenberg, J.I.
Deposit date:2010-07-19
Release date:2011-01-26
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:The N-Terminal Tail of hERG Contains an Amphipathic alpha-Helix That Regulates Channel Deactivation
PLoS ONE, 6, 2011
2MI5
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BU of 2mi5 by Molmil
Structure of insect-specific sodium channel toxin mu-Dc1a
Descriptor: Mu-diguetoxin-Dc1a
Authors:Bende, N.S, Mobli, M, King, G.F.
Deposit date:2013-12-08
Release date:2014-07-23
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:A distinct sodium channel voltage-sensor locus determines insect selectivity of the spider toxin Dc1a.
Nat Commun, 5, 2014
2NDO
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BU of 2ndo by Molmil
Structure of EcDsbA-sulfonamide1 complex
Descriptor: 2-{[(4-iodophenyl)sulfonyl]amino}benzoic acid, Thiol:disulfide interchange protein DsbA
Authors:Williams, M.L, Doak, B.C, Vazirani, M, Ilyichova, O, Wang, G, Bermel, W, Simpson, J.S, Chalmers, D.K, King, G.F, Mobli, M, Scanlon, M.J.
Deposit date:2016-08-22
Release date:2017-02-08
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Determination of ligand binding modes in weak protein-ligand complexes using sparse NMR data.
J.Biomol.Nmr, 66, 2016
2N6O
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BU of 2n6o by Molmil
Structure of spider-venom peptide Hm1a
Descriptor: Kappa-theraphotoxin-Hm1a
Authors:Undheim, E.A.B, King, G.F, Mobli, M.
Deposit date:2015-08-27
Release date:2016-09-07
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structure of spider-venom peptide Hm1a
To be Published
2N8K
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BU of 2n8k by Molmil
Chemical Shift Assignments and Structure Determination for spider toxin, U33-theraphotoxin-Cg1c
Descriptor: U33-theraphotoxin-Cg1b
Authors:Chin, Y.K.-Y, Pineda, S.S, Mobli, M, King, G.F.
Deposit date:2015-10-20
Release date:2016-08-31
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural venomics reveals evolution of a complex venom by duplication and diversification of an ancient peptide-encoding gene.
Proc.Natl.Acad.Sci.USA, 117, 2020
2N6R
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BU of 2n6r by Molmil
NMR structure of spider toxin U4-hexatoxin-Hi1a
Descriptor: U4-hexatoxin-Hi1a
Authors:Pineda, S.S, Chin, Y.K.-Y, King, G.F.
Deposit date:2015-08-28
Release date:2016-08-31
Last modified:2023-03-08
Method:SOLUTION NMR
Cite:Structural venomics reveals evolution of a complex venom by duplication and diversification of an ancient peptide-encoding gene.
Proc.Natl.Acad.Sci.USA, 117, 2020
2NBC
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BU of 2nbc by Molmil
Resonance assignments and structure determination of poneritoxin, omega-PONTX-Ae1a, from Anochetus emarginatus
Descriptor: poneritoxin
Authors:Chin, Y.K.-Y, Touchard, A, King, G.F.
Deposit date:2016-02-03
Release date:2017-01-11
Method:SOLUTION NMR
Cite:Isolation and characterization of a structurally unique beta-hairpin venom peptide from the predatory ant Anochetus emarginatus.
Biochim.Biophys.Acta, 1860, 2016
2N8F
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BU of 2n8f by Molmil
Chemical shift assignments and structure calculation of spider toxin pi-hexatoxin-Hi1a
Descriptor: spider toxin pi-hexatoxin-Hi1a
Authors:Chin, Y.K.-Y, Pineda, S.S, Mobli, M, King, G.F.
Deposit date:2015-10-13
Release date:2016-10-19
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Potent neuroprotection after stroke afforded by a double-knot spider-venom peptide that inhibits acid-sensing ion channel 1a.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
2N6N
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BU of 2n6n by Molmil
Structure Determination for spider toxin, U4-agatoxin-Ao1a
Descriptor: U4-agatoxin-Ao1a
Authors:Pineda, S.S, Chin, Y.K.-Y, Mobli, M.S, King, G.F.
Deposit date:2015-08-27
Release date:2016-08-31
Last modified:2023-03-08
Method:SOLUTION NMR
Cite:Structural venomics reveals evolution of a complex venom by duplication and diversification of an ancient peptide-encoding gene.
Proc.Natl.Acad.Sci.USA, 117, 2020
2N1N
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BU of 2n1n by Molmil
Solution structure of VSTx1
Descriptor: Kappa-theraphotoxin-Gr3a
Authors:Lau, H.Y, King, G.F, Mobli, M.
Deposit date:2015-04-12
Release date:2016-03-02
Last modified:2016-10-12
Method:SOLUTION NMR
Cite:Molecular basis of the interaction between gating modifier spider toxins and the voltage sensor of voltage-gated ion channels.
Sci Rep, 6
2MT7
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BU of 2mt7 by Molmil
Solution structure of spider-venom peptide Hs1a
Descriptor: Hs1a
Authors:Klint, J.K, King, G.F, Mobli, M.
Deposit date:2014-08-14
Release date:2015-08-19
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Nav1.7 inhibitors normalise mechanical responses in chronic visceral hypersensitivity
To be Published

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