7L8K
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![BU of 7l8k by Molmil](/molmil-images/mine/7l8k) | Crystal structure of human GPX4-U46C | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, PHOSPHATE ION, ... | Authors: | Forouhar, F, Liu, H, Seibt, T, Saneto, R, Wigby, K, Friedman, J, Xia, X, Shchepinov, M.S, Ramesh, S, Conrad, M, Stockwell, B.R. | Deposit date: | 2020-12-31 | Release date: | 2021-12-29 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.38 Å) | Cite: | Patient-derived variant of GPX4 reveals the structural basis for its catalytic activity and degradation mechanism Nat.Chem.Biol., 2021
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7L8Q
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![BU of 7l8q by Molmil](/molmil-images/mine/7l8q) | Crystal structure of human GPX4-U46C with oxidized Cys-46 | Descriptor: | ACETATE ION, Phospholipid hydroperoxide glutathione peroxidase | Authors: | Forouhar, F, Liu, H, Seibt, T, Saneto, R, Wigby, K, Friedman, J, Xia, X, Shchepinov, M.S, Ramesh, S, Conrad, M, Stockwell, B.R. | Deposit date: | 2020-12-31 | Release date: | 2021-12-29 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.48 Å) | Cite: | Patient-derived variant of GPX4 reveals the structural basis for its catalytic activity and degradation mechanism Nat.Chem.Biol., 2021
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7L8R
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![BU of 7l8r by Molmil](/molmil-images/mine/7l8r) | Crystal structure of human GPX4-U46C mutant K48A | Descriptor: | Isoform Cytoplasmic of Phospholipid hydroperoxide glutathione peroxidase, THIOCYANATE ION | Authors: | Forouhar, F, Liu, H, Seibt, T, Saneto, R, Wigby, K, Friedman, J, Xia, X, Shchepinov, M.S, Ramesh, S, Conrad, M, Stockwell, B.R. | Deposit date: | 2020-12-31 | Release date: | 2021-12-29 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | Patient-derived variant of GPX4 reveals the structural basis for its catalytic activity and degradation mechanism Nat.Chem.Biol., 2021
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7L8L
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![BU of 7l8l by Molmil](/molmil-images/mine/7l8l) | Crystal structure of human R152H GPX4-U46C | Descriptor: | Phospholipid hydroperoxide glutathione peroxidase, THIOCYANATE ION | Authors: | Forouhar, F, Liu, H, Seibt, T, Saneto, R, Wigby, K, Friedman, J, Xia, X, Shchepinov, M.S, Ramesh, S, Conrad, M, Stockwell, B.R. | Deposit date: | 2020-12-31 | Release date: | 2021-12-29 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.61 Å) | Cite: | Patient-derived variant of GPX4 reveals the structural basis for its catalytic activity and degradation mechanism Nat.Chem.Biol., 2021
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8Q8N
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![BU of 8q8n by Molmil](/molmil-images/mine/8q8n) | Crystal structure of human GPX4-U46C-I129S-L130S | Descriptor: | Phospholipid hydroperoxide glutathione peroxidase | Authors: | Bostock, M.J, Mourao, A, Napolitano, V, Sattler, M, Conrad, M, Popowicz, G. | Deposit date: | 2023-08-18 | Release date: | 2024-08-28 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | An ultra-rare variant of GPX4 reveals the structural basis to avert neurodegeneration To Be Published
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8Q8J
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![BU of 8q8j by Molmil](/molmil-images/mine/8q8j) | Crystal structure of human GPX4-R152H | Descriptor: | Glutathione peroxidase | Authors: | Napolitano, V, Mourao, A, Kolonko, M, Bostock, M.J, Sattler, M, Conrad, M, Popowicz, G. | Deposit date: | 2023-08-18 | Release date: | 2024-08-28 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of human GPX4-R152H To Be Published
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7L8M
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![BU of 7l8m by Molmil](/molmil-images/mine/7l8m) | Crystal structure of human GPX4-U46C mutant K48L | Descriptor: | Phospholipid hydroperoxide glutathione peroxidase | Authors: | Forouhar, F, Liu, H, Seibt, T, Saneto, R, Friedman, J, Xia, X, Shchepinov, M.S, Ramesh, S, Conrad, M, Stockwell, B.R. | Deposit date: | 2020-12-31 | Release date: | 2021-12-29 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | Patient-derived variant of GPX4 reveals the structural basis for its catalytic activity and degradation mechanism Nat.Chem.Biol., 2021
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