4CMQ
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![BU of 4cmq by Molmil](/molmil-images/mine/4cmq) | Crystal structure of Mn-bound S.pyogenes Cas9 | Descriptor: | CRISPR-ASSOCIATED ENDONUCLEASE CAS9/CSN1, MANGANESE (II) ION, SULFATE ION | Authors: | Jinek, M, Jiang, F, Taylor, D.W, Sternberg, S.H, Kaya, E, Ma, E, Anders, C, Hauer, M, Zhou, K, Lin, S, Kaplan, M, Iavarone, A.T, Charpentier, E, Nogales, E, Doudna, J.A. | Deposit date: | 2014-01-17 | Release date: | 2014-02-12 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.09 Å) | Cite: | Structures of Cas9 Endonucleases Reveal RNA- Mediated Conformational Activation Science, 343, 2014
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7RZY
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![BU of 7rzy by Molmil](/molmil-images/mine/7rzy) | CryoEM structure of Vibrio cholerae transposon Tn6677 AAA+ ATPase TnsC | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Tn6677 Vibrio cholerae transposon TnsC (VchTnsC) | Authors: | Hoffmann, F.T, Kim, M, Beh, L.Y, Wang, J, Vo, P.L.H, Gelsinger, D.R, Acree, C, Mohabir, J.T, Fernandez, I.S, Sternberg, S.H. | Deposit date: | 2021-08-28 | Release date: | 2022-06-08 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Selective TnsC recruitment enhances the fidelity of RNA-guided transposition. Nature, 609, 2022
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4AL6
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![BU of 4al6 by Molmil](/molmil-images/mine/4al6) | |
4AL5
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![BU of 4al5 by Molmil](/molmil-images/mine/4al5) | |
4AL7
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![BU of 4al7 by Molmil](/molmil-images/mine/4al7) | |
7UFI
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![BU of 7ufi by Molmil](/molmil-images/mine/7ufi) | VchTnsC AAA+ ATPase with DNA, single heptamer | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(P*CP*TP*CP*CP*AP*GP*TP*AP*CP*AP*GP*CP*GP*CP*GP*GP*CP*TP*GP*AP*A)-3'), DNA (5'-D(P*TP*TP*CP*AP*GP*CP*CP*GP*CP*GP*CP*TP*GP*TP*AP*CP*TP*GP*GP*AP*G)-3'), ... | Authors: | Fernandez, I.S, Sternberg, S.H. | Deposit date: | 2022-03-22 | Release date: | 2022-06-08 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Selective TnsC recruitment enhances the fidelity of RNA-guided transposition. Nature, 609, 2022
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7UFM
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![BU of 7ufm by Molmil](/molmil-images/mine/7ufm) | VchTnsC AAA+ with DNA (double heptamer) | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, DNA (36-MER), VchTnsC | Authors: | Fernandez, I.S, Sternberg, S.H. | Deposit date: | 2022-03-22 | Release date: | 2022-06-08 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Selective TnsC recruitment enhances the fidelity of RNA-guided transposition. Nature, 609, 2022
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4CMP
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![BU of 4cmp by Molmil](/molmil-images/mine/4cmp) | Crystal structure of S. pyogenes Cas9 | Descriptor: | CRISPR-ASSOCIATED ENDONUCLEASE CAS9/CSN1, MAGNESIUM ION, SULFATE ION | Authors: | Jinek, M, Jiang, F, Taylor, D.W, Sternberg, S.H, Kaya, E, Ma, E, Anders, C, Hauer, M, Zhou, K, Lin, S, Kaplan, M, Iavarone, A.T, Charpentier, E, Nogales, E, Doudna, J.A. | Deposit date: | 2014-01-16 | Release date: | 2014-02-12 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.62 Å) | Cite: | Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation. Science, 343, 2014
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6PIG
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![BU of 6pig by Molmil](/molmil-images/mine/6pig) | V. cholerae TniQ-Cascade complex, closed conformation | Descriptor: | RNA (60-MER), TniQ monomer 1, TniQ monomer 2, ... | Authors: | Halpin-Healy, T, Klompe, S, Sternberg, S.H. | Deposit date: | 2019-06-26 | Release date: | 2019-10-02 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural basis of DNA targeting by a transposon-encoded CRISPR-Cas system. Nature, 577, 2020
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6PIJ
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![BU of 6pij by Molmil](/molmil-images/mine/6pij) | Target DNA-bound V. cholerae TniQ-Cascade complex, closed conformation | Descriptor: | Non-targeting strand ssDNA, Targeting strand ssDNA, TniQ monomer 2, ... | Authors: | Halpin-Healy, T, Klompe, S, Sternberg, S.H. | Deposit date: | 2019-06-26 | Release date: | 2019-10-02 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural basis of DNA targeting by a transposon-encoded CRISPR-Cas system. Nature, 577, 2020
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6PIF
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![BU of 6pif by Molmil](/molmil-images/mine/6pif) | V. cholerae TniQ-Cascade complex, open conformation | Descriptor: | Cas7, type I-F CRISPR-associated protein, TniQ monomer 1, ... | Authors: | Halpin-Healy, T, Klompe, S, Sternberg, S.H. | Deposit date: | 2019-06-26 | Release date: | 2019-10-02 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural basis of DNA targeting by a transposon-encoded CRISPR-Cas system. Nature, 577, 2020
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4OGE
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![BU of 4oge by Molmil](/molmil-images/mine/4oge) | Crystal structure of the Type II-C Cas9 enzyme from Actinomyces naeslundii | Descriptor: | HNH endonuclease domain protein, MAGNESIUM ION, SPERMIDINE, ... | Authors: | Jiang, F, Ma, E, Lin, S, Doudna, J.A. | Deposit date: | 2014-01-15 | Release date: | 2014-02-12 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.201 Å) | Cite: | Structures of Cas9 endonucleases reveal RNA-mediated conformational activation. Science, 343, 2014
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4OGC
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![BU of 4ogc by Molmil](/molmil-images/mine/4ogc) | Crystal structure of the Type II-C Cas9 enzyme from Actinomyces naeslundii | Descriptor: | ACETATE ION, HNH endonuclease domain protein, MAGNESIUM ION, ... | Authors: | Jiang, F, Ma, E, Lin, S, Doudna, J.A. | Deposit date: | 2014-01-15 | Release date: | 2014-02-12 | Last modified: | 2014-03-26 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structures of Cas9 endonucleases reveal RNA-mediated conformational activation. Science, 343, 2014
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