8RDX
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![BU of 8rdx by Molmil](/molmil-images/mine/8rdx) | PGGtase I in complex with probe BAY-6092 | Descriptor: | (5~{R})-5-(2-methoxyphenyl)-9-[(2~{R})-3,3,3-tris(fluoranyl)-2-methoxy-2-phenyl-propanoyl]-3,9-diazaspiro[5.5]undecan-2-one, CHLORIDE ION, DIPHOSPHATE, ... | Authors: | Steuber, H. | Deposit date: | 2023-12-08 | Release date: | 2024-02-14 | Last modified: | 2024-04-10 | Method: | X-RAY DIFFRACTION (3.67 Å) | Cite: | Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling. Cell Chem Biol, 2024
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3OLM
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![BU of 3olm by Molmil](/molmil-images/mine/3olm) | Structure and Function of a Ubiquitin Binding Site within the Catalytic Domain of a HECT Ubiquitin Ligase | Descriptor: | E3 ubiquitin-protein ligase RSP5, Ubiquitin | Authors: | Kim, H.C, Steffen, A, Chen, J, Huibregtse, J.M. | Deposit date: | 2010-08-26 | Release date: | 2011-03-23 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.495 Å) | Cite: | Structure and function of a HECT domain ubiquitin-binding site. Embo Rep., 12, 2011
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4YDH
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![BU of 4ydh by Molmil](/molmil-images/mine/4ydh) | The structure of human FMNL1 N-terminal domains bound to Cdc42 | Descriptor: | Cell division control protein 42 homolog, Formin-like protein 1, MAGNESIUM ION, ... | Authors: | Kuhn, S, Anand, K, Geyer, M. | Deposit date: | 2015-02-22 | Release date: | 2015-05-13 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | The structure of FMNL2-Cdc42 yields insights into the mechanism of lamellipodia and filopodia formation. Nat Commun, 6, 2015
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4YC7
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![BU of 4yc7 by Molmil](/molmil-images/mine/4yc7) | |
6YHM
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![BU of 6yhm by Molmil](/molmil-images/mine/6yhm) | Crystal structure of the C-terminal domain of CNFy from Yersinia pseudotuberculosis | Descriptor: | Cytotoxic necrotizing factor, MAGNESIUM ION | Authors: | Lukat, P, Gazdag, E.M, Heidler, T.V, Blankenfeldt, W. | Deposit date: | 2020-03-30 | Release date: | 2020-12-30 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.13 Å) | Cite: | Crystal structure of bacterial cytotoxic necrotizing factor CNF Y reveals molecular building blocks for intoxication. Embo J., 40, 2021
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6YHN
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![BU of 6yhn by Molmil](/molmil-images/mine/6yhn) | Crystal structure of domains 4-5 of CNFy from Yersinia pseudotuberculosis | Descriptor: | (R,R)-2,3-BUTANEDIOL, CHLORIDE ION, Cytotoxic necrotizing factor, ... | Authors: | Lukat, P, Gazdag, E.M, Heidler, T.V, Blankenfeldt, W. | Deposit date: | 2020-03-30 | Release date: | 2020-12-30 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of bacterial cytotoxic necrotizing factor CNF Y reveals molecular building blocks for intoxication. Embo J., 40, 2021
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6YHL
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![BU of 6yhl by Molmil](/molmil-images/mine/6yhl) | |
6YHK
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![BU of 6yhk by Molmil](/molmil-images/mine/6yhk) | Crystal structure of full-length CNFy (C866S) from Yersinia pseudotuberculosis | Descriptor: | CHLORIDE ION, Cytotoxic necrotizing factor, SULFATE ION | Authors: | Lukat, P, Gazdag, E.M, Heidler, T.V, Blankenfeldt, W. | Deposit date: | 2020-03-30 | Release date: | 2020-12-30 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of bacterial cytotoxic necrotizing factor CNF Y reveals molecular building blocks for intoxication. Embo J., 40, 2021
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