3K6N
| Crystal structure of the S225E mutant Kir3.1 cytoplasmic pore domain | Descriptor: | G protein-activated inward rectifier potassium channel 1, SODIUM ION | Authors: | Xu, Y, Shin, H.G, Szep, S, Lu, Z. | Deposit date: | 2009-10-09 | Release date: | 2009-11-17 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Physical determinants of strong voltage sensitivity of K(+) channel block. Nat.Struct.Mol.Biol., 16, 2009
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7V8I
| LolCD(E171Q)E with bound AMPPNP in nanodiscs | Descriptor: | Lipoprotein-releasing system ATP-binding protein LolD, Lipoprotein-releasing system transmembrane protein LolC, Lipoprotein-releasing system transmembrane protein LolE, ... | Authors: | Bei, W.W, Luo, Q.S, Shi, H.G, Zhang, X.Z, Huang, Y.H. | Deposit date: | 2021-08-23 | Release date: | 2022-08-31 | Last modified: | 2023-10-04 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Cryo-EM structures of LolCDE reveal the molecular mechanism of bacterial lipoprotein sorting in Escherichia coli. Plos Biol., 20, 2022
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7V8M
| LolCDE-apo in nanodiscs | Descriptor: | Lipoprotein-releasing system ATP-binding protein LolD, Lipoprotein-releasing system transmembrane protein LolC, Lipoprotein-releasing system transmembrane protein LolE | Authors: | Luo, Q.S, Bei, W.W, Shi, H.G, Zhang, X.Z, Huang, Y.H. | Deposit date: | 2021-08-23 | Release date: | 2022-08-31 | Last modified: | 2023-10-04 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Cryo-EM structures of LolCDE reveal the molecular mechanism of bacterial lipoprotein sorting in Escherichia coli. Plos Biol., 20, 2022
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7V8L
| LolCDE with bound RcsF in nanodiscs | Descriptor: | (2R)-3-{[(2S)-3-HYDROXY-2-(PALMITOYLAMINO)PROPYL]THIO}PROPANE-1,2-DIYL DIHEXADECANOATE, Lipoprotein-releasing system ATP-binding protein LolD, Lipoprotein-releasing system transmembrane protein LolC, ... | Authors: | Bei, W.W, Luo, Q.S, Shi, H.G, Zhang, X.Z, Huang, Y.H. | Deposit date: | 2021-08-23 | Release date: | 2022-09-21 | Last modified: | 2023-10-04 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Cryo-EM structures of LolCDE reveal the molecular mechanism of bacterial lipoprotein sorting in Escherichia coli. Plos Biol., 20, 2022
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7JUO
| CBP bromodomain complexed with YF2-23 | Descriptor: | CREB-binding protein, N-{1-[1,1-di(pyridin-2-yl)ethyl]-6-(1-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-3-yl)-1H-indol-4-yl}ethanesulfonamide | Authors: | Ratia, K.M, Xiong, R, Principe, D, Li, Y, Huang, F, Rana, A, Thatcher, G. | Deposit date: | 2020-08-20 | Release date: | 2021-09-01 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | XP-524 is a dual-BET/EP300 inhibitor that represses oncogenic KRAS and potentiates immune checkpoint inhibition in pancreatic cancer. Proc.Natl.Acad.Sci.USA, 119, 2022
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7YC5
| Cryo-EM structure of SARS-CoV-2 spike in complex with K202.B bispecific antibody | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain from K202.B, bispecific antibody, ... | Authors: | Yoo, Y, Cho, H.S. | Deposit date: | 2022-06-30 | Release date: | 2023-07-05 | Last modified: | 2024-10-16 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Novel bispecific human antibody platform specifically targeting a fully open spike conformation potently neutralizes multiple SARS-CoV-2 variants. Antiviral Res., 212, 2023
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