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7S7B
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BU of 7s7b by Molmil
Human Nuclear exosome targeting (NEXT) complex homodimer bound to RNA (substrate 1)
Descriptor: Exosome RNA helicase MTR4, RNA (46-MER), RNA-binding protein 7, ...
Authors:Puno, M.R, Lima, C.D.
Deposit date:2021-09-15
Release date:2022-06-15
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (4.06 Å)
Cite:Structural basis for RNA surveillance by the human nuclear exosome targeting (NEXT) complex.
Cell, 185, 2022
7S7C
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BU of 7s7c by Molmil
Human Nuclear Exosome Targeting (NEXT) complex bound to RNA (substrate 2)
Descriptor: Exosome RNA helicase MTR4, RNA (30-MER), RNA-binding protein 7, ...
Authors:Puno, M.R, Lima, C.D.
Deposit date:2021-09-15
Release date:2022-06-15
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.62 Å)
Cite:Structural basis for RNA surveillance by the human nuclear exosome targeting (NEXT) complex.
Cell, 185, 2022
4BTE
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BU of 4bte by Molmil
DJ-1 Cu(I) complex
Descriptor: COPPER (I) ION, PROTEIN DJ-1
Authors:Puno, M.R.A, Odell, M, Moody, P.C.E.
Deposit date:2013-06-14
Release date:2013-11-06
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:Structure of Cu(I)-Bound Dj-1 Reveals a Biscysteinate Metal Binding Site at the Homodimer Interface: Insights Into Mutational Inactivation of Dj-1 in Parkinsonism.
J.Am.Chem.Soc., 135, 2013
6C90
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BU of 6c90 by Molmil
Human Mtr4 helicase in complex with ZCCHC8-CTD
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Exosome RNA helicase MTR4,Exosome RNA helicase MTR4, L(+)-TARTARIC ACID, ...
Authors:Puno, M.R, Lima, C.D.
Deposit date:2018-01-25
Release date:2018-05-30
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for MTR4-ZCCHC8 interactions that stimulate the MTR4 helicase in the nuclear exosome-targeting complex.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6D6Q
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BU of 6d6q by Molmil
Human nuclear exosome-MTR4 RNA complex - overall reconstruction
Descriptor: DNA/RNA (62-MER), Exosome RNA helicase MTR4, Exosome complex component CSL4, ...
Authors:Weick, E.-M, Lima, C.D.
Deposit date:2018-04-22
Release date:2018-06-20
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.45 Å)
Cite:Helicase-Dependent RNA Decay Illuminated by a Cryo-EM Structure of a Human Nuclear RNA Exosome-MTR4 Complex.
Cell, 173, 2018
6D6R
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BU of 6d6r by Molmil
Human nuclear exosome-MTR4 RNA complex - composite map after focused reconstruction
Descriptor: DNA/RNA (62-MER), Exosome RNA helicase MTR4, Exosome complex component CSL4, ...
Authors:Weick, E.-M, Lima, C.D.
Deposit date:2018-04-22
Release date:2018-06-20
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.45 Å)
Cite:Helicase-Dependent RNA Decay Illuminated by a Cryo-EM Structure of a Human Nuclear RNA Exosome-MTR4 Complex.
Cell, 173, 2018

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數據於2024-07-10公開中

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