1DD9
| STRUCTURE OF THE DNAG CATALYTIC CORE | Descriptor: | DNA PRIMASE, STRONTIUM ION | Authors: | Keck, J.L, Roche, D.D, Lynch, A.S, Berger, J.M. | Deposit date: | 1999-11-09 | Release date: | 2000-04-07 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure of the RNA polymerase domain of E. coli primase. Science, 287, 2000
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1DDE
| STRUCTURE OF THE DNAG CATALYTIC CORE | Descriptor: | DNA PRIMASE, YTTRIUM ION | Authors: | Keck, J.L, Roche, D.D, Lynch, A.S, Berger, J.M. | Deposit date: | 1999-11-09 | Release date: | 2000-04-07 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure of the RNA polymerase domain of E. coli primase. Science, 287, 2000
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2FL7
| S. cerevisiae Sir3 BAH domain | Descriptor: | Regulatory protein SIR3 | Authors: | Keck, J.L, Hou, Z, Daner, J.R, Fox, C.A. | Deposit date: | 2006-01-05 | Release date: | 2006-05-09 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structure of the Sir3 protein bromo adjacent homology (BAH) domain from S. cerevisiae at 1.95 A resolution. Protein Sci., 15, 2006
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2RHF
| D. radiodurans RecQ HRDC domain 3 | Descriptor: | DNA helicase RecQ, PHOSPHATE ION | Authors: | Keck, J.L, Killoran, M.P. | Deposit date: | 2007-10-09 | Release date: | 2008-04-22 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Structure and function of the regulatory C-terminal HRDC domain from Deinococcus radiodurans RecQ. Nucleic Acids Res., 36, 2008
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3PLW
| Ref protein from P1 bacteriophage | Descriptor: | Recombination enhancement function protein, SULFATE ION, ZINC ION | Authors: | Keck, J.L, Lu, D, Cox, M.M. | Deposit date: | 2010-11-15 | Release date: | 2010-12-29 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Creating Directed Double-strand Breaks with the Ref Protein: A NOVEL RecA-DEPENDENT NUCLEASE FROM BACTERIOPHAGE P1. J.Biol.Chem., 286, 2011
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3C95
| Exonuclease I (apo) | Descriptor: | Exodeoxyribonuclease I, MAGNESIUM ION | Authors: | Keck, J.L, Lu, D. | Deposit date: | 2008-02-15 | Release date: | 2008-07-08 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural basis of Escherichia coli single-stranded DNA-binding protein stimulation of exonuclease I. Proc.Natl.Acad.Sci.USA, 105, 2008
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3C9B
| Crystal structure of SeMet Vps75 | Descriptor: | Vacuolar protein sorting-associated protein 75 | Authors: | Keck, J.L, Berndsen, C.E, Tsubota, T, Lindner, S.E, Lee, S, Holton, J.M, Kaufman, P.D, Denu, J.M. | Deposit date: | 2008-02-15 | Release date: | 2008-08-12 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.42 Å) | Cite: | Molecular functions of the histone acetyltransferase chaperone complex Rtt109-Vps75 Nat.Struct.Mol.Biol., 15, 2008
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1TXY
| E. coli PriB | Descriptor: | Primosomal replication protein n | Authors: | Keck, J.L, Lopper, M, Holton, J.M. | Deposit date: | 2004-07-06 | Release date: | 2004-11-16 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of PriB, a component of the Escherichia coli replication restart primosome Structure, 12, 2004
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4DAY
| Crystal structure of the RMI core complex with MM2 peptide from FANCM | Descriptor: | Fanconi anemia group M protein, RecQ-mediated genome instability protein 1, RecQ-mediated genome instability protein 2 | Authors: | Hoadley, K.A, Keck, J.L. | Deposit date: | 2012-01-13 | Release date: | 2012-03-14 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Defining the molecular interface that connects the Fanconi anemia protein FANCM to the Bloom syndrome dissolvasome. Proc.Natl.Acad.Sci.USA, 109, 2012
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2PNH
| Escherichia coli PriB E39A variant | Descriptor: | Primosomal replication protein n | Authors: | Lopper, M.E, Keck, J.L. | Deposit date: | 2007-04-24 | Release date: | 2007-08-07 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | A hand-off mechanism for primosome assembly in replication restart. Mol.Cell, 26, 2007
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3SXU
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8FAK
| DNA replication fork binding triggers structural changes in the PriA DNA helicase that regulate the PriA-PriB replication restart pathway in E. coli | Descriptor: | DNA (5'-D(P*CP*AP*GP*AP*CP*TP*CP*AP*TP*TP*TP*AP*GP*CP*CP*CP*TP*TP*AP*TP*CP*CP*G)-3'), DNA (5'-D(P*CP*GP*GP*AP*TP*AP*AP*GP*GP*GP*CP*TP*GP*AP*GP*CP*AP*CP*GP*CP*CP*GP*A)-3'), DNA (5'-D(P*TP*CP*GP*GP*CP*GP*TP*GP*CP*TP*C)-3'), ... | Authors: | Duckworth, A.T, Ducos, P.L, McMillan, S.D, Satyshur, K.A, Blumenthal, K.H, Deorio, H.R, Larson, J.A, Sandler, S.J, Grant, T, Keck, J.L. | Deposit date: | 2022-11-28 | Release date: | 2023-05-10 | Last modified: | 2023-05-24 | Method: | ELECTRON MICROSCOPY (3.22 Å) | Cite: | Replication fork binding triggers structural changes in the PriA helicase that govern DNA replication restart in E. coli. Nat Commun, 14, 2023
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4QRH
| Molecular mechanism and evolution of guanylate kinase regulation by (p)ppGpp | Descriptor: | 1,2-ETHANEDIOL, Guanylate kinase, MAGNESIUM ION, ... | Authors: | Liu, K, Krasny, K, Myers, A.R, Satyshur, K.A, Keck, J.L, Wnag, J.D. | Deposit date: | 2014-07-01 | Release date: | 2015-02-25 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Molecular Mechanism and Evolution of Guanylate Kinase Regulation by (p)ppGpp. Mol.Cell, 57, 2015
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4TMU
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1WUD
| E. coli RecQ HRDC domain | Descriptor: | ATP-dependent DNA helicase recQ | Authors: | Bernstein, D.A, Keck, J.L. | Deposit date: | 2004-12-04 | Release date: | 2005-08-09 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Conferring Substrate Specificity to DNA Helicases: Role of the RecQ HRDC Domain STRUCTURE, 13, 2005
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1YO8
| Structure of the C-terminal domain of human thrombospondin-2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Carlson, C.B, Bernstein, D.A, Annis, D.S, Misenheimer, T.M, Hannah, B.A, Mosher, D.F, Keck, J.L. | Deposit date: | 2005-01-26 | Release date: | 2005-09-27 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of the calcium-rich signature domain of human thrombospondin-2 Nat.Struct.Mol.Biol., 12, 2005
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1ZHI
| Complex of the S. cerevisiae Orc1 and Sir1 interacting domains | Descriptor: | Origin recognition complex subunit 1, Regulatory protein SIR1 | Authors: | Hou, Z, Bernstein, D.A, Fox, C.A, Keck, J.L. | Deposit date: | 2005-04-25 | Release date: | 2005-06-07 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural basis of the Sir1-origin recognition complex interaction in transcriptional silencing. Proc.Natl.Acad.Sci.Usa, 102, 2005
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3VDY
| B. subtilis SsbB/ssDNA | Descriptor: | 5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3', Single-stranded DNA-binding protein ssbB | Authors: | Yadav, T, Carrasco, B, Myers, A.R, George, N.P, Keck, J.L, Alonso, J.C. | Deposit date: | 2012-01-06 | Release date: | 2012-03-14 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Genetic recombination in Bacillus subtilis: a division of labor between two single-strand DNA-binding proteins. Nucleic Acids Res., 40, 2012
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3V8E
| Crystal structure of the yeast nicotinamidase Pnc1p bound to the inhibitor nicotinaldehyde | Descriptor: | MAGNESIUM ION, Nicotinamidase, ZINC ION | Authors: | Hoadley, K.A, Smith, B.C, Denu, J.M, Keck, J.L. | Deposit date: | 2011-12-22 | Release date: | 2012-01-25 | Method: | X-RAY DIFFRACTION (2.71 Å) | Cite: | Structural and Kinetic Isotope Effect Studies of Nicotinamidase (Pnc1) from Saccharomyces cerevisiae. Biochemistry, 51, 2012
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3UF7
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3UFM
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3UDG
| Structure of Deinococcus radiodurans SSB bound to ssDNA | Descriptor: | 5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3', Single-stranded DNA-binding protein, THYMIDINE-5'-PHOSPHATE | Authors: | George, N.P, Ngo, K.V, Chitteni-Patu, S, Norais, C.A, Battista, J.R, Cox, M.M, Keck, J.L. | Deposit date: | 2011-10-28 | Release date: | 2012-05-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure and Cellular Dynamics of Deinococcus radiodurans Single-stranded DNA (ssDNA)-binding Protein (SSB)-DNA Complexes. J.Biol.Chem., 287, 2012
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6W1I
| Re-interpretation of ppGpp (G4P) electron density in the deposited crystal structure of Xanthine phosphoribosyltransferase (XPRT) (1Y0B). | Descriptor: | GUANOSINE-5',3'-TETRAPHOSPHATE, SODIUM ION, Xanthine phosphoribosyltransferase | Authors: | Satyshur, K.A, Anderson, B.W, Keck, J.L, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2020-03-04 | Release date: | 2020-07-29 | Last modified: | 2021-04-07 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Molecular Mechanism of Regulation of the Purine Salvage Enzyme XPRT by the Alarmones pppGpp, ppGpp, and pGpp. J.Mol.Biol., 432, 2020
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5JRJ
| Crystal Structure of Herbaspirillum seropedicae RecA | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, ... | Authors: | Leite, W.C, Galvao, C.W, Saab, S.C, Iulek, J, Etto, R.M, Steffens, M.B.R, Chitteni-Pattu, S, Stanage, T, Keck, J.L, Cox, M.M. | Deposit date: | 2016-05-06 | Release date: | 2016-08-03 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural and Functional Studies of H. seropedicae RecA Protein - Insights into the Polymerization of RecA Protein as Nucleoprotein Filament. PLoS ONE, 11, 2016
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1Z1A
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