4CP3
 
 | | The structure of BCL6 BTB (POZ) domain in complex with the ansamycin antibiotic rifabutin. | | Descriptor: | B-CELL LYMPHOMA 6 PROTEIN, RIFABUTIN | | Authors: | Evans, S.E, Fairall, L, Goult, B.T, Jamieson, A.G, Ferrigno, P.K, Ford, R, Wagner, S.D, Schwabe, J.W.R. | | Deposit date: | 2014-01-31 | | Release date: | 2014-03-19 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | The Ansamycin Antibiotic, Rifamycin Sv, Inhibits Bcl6 Transcriptional Repression and Forms a Complex with the Bcl6-Btb/Poz Domain.
Plos One, 9, 2014
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8RPC
 | | Crystal structure of PfCLK3 with TCMDC-135051 | | Descriptor: | 1,2-ETHANEDIOL, 4-[2-[5-(diethylaminomethyl)-2-methoxy-phenyl]-1~{H}-pyrrolo[2,3-b]pyridin-4-yl]-2-propan-2-yl-benzoic acid, GLYCEROL, ... | | Authors: | Yelland, T.S, Benazir, A, Hole, A. | | Deposit date: | 2024-01-15 | | Release date: | 2024-11-06 | | Last modified: | 2024-11-27 | | Method: | X-RAY DIFFRACTION (2.079 Å) | | Cite: | Targeting Pf CLK3 with Covalent Inhibitors: A Novel Strategy for Malaria Treatment.
J.Med.Chem., 67, 2024
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5ICN
 | | HDAC1:MTA1 in complex with inositol-6-phosphate and a novel peptide inhibitor based on histone H4 | | Descriptor: | GLY-ALA-6A0-ARG-HIS, Histone deacetylase 1, INOSITOL HEXAKISPHOSPHATE, ... | | Authors: | Millard, C.J, Robertson, N.S, Watson, P.J, Jameson, A.G, Schwabe, J.W.R. | | Deposit date: | 2016-02-23 | | Release date: | 2016-05-11 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Insights into the activation mechanism of class I HDAC complexes by inositol phosphates.
Nat Commun, 7, 2016
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5LXM
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6SQO
 | | Crystal structure of human MDM2 RING domain homodimer bound to UbcH5B-Ub | | Descriptor: | CHLORIDE ION, E3 ubiquitin-protein ligase Mdm2, NITRATE ION, ... | | Authors: | Magnussen, H.M, Ahmed, S.F, Huang, D.T. | | Deposit date: | 2019-09-04 | | Release date: | 2020-05-06 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.41 Å) | | Cite: | Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain.
Nat Commun, 11, 2020
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6SQS
 | | Crystal structure of cat phospho-Ser429 MDM2 RING domain bound to UbcH5B-Ub | | Descriptor: | E3 ubiquitin-protein ligase Mdm2, Ubiquitin-40S ribosomal protein S27a, Ubiquitin-conjugating enzyme E2 D2, ... | | Authors: | Magnussen, H.M, Ahmed, S.F, Huang, D.T. | | Deposit date: | 2019-09-04 | | Release date: | 2020-05-06 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (1.83 Å) | | Cite: | Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain.
Nat Commun, 11, 2020
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6SQP
 | | Crystal structure of Cat MDM2-S429E RING domain homodimer | | Descriptor: | CHLORIDE ION, E3 ubiquitin-protein ligase Mdm2, NITRATE ION, ... | | Authors: | Magnussen, H.M, Ahmed, S.F, Huang, D.T. | | Deposit date: | 2019-09-04 | | Release date: | 2020-05-06 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.21 Å) | | Cite: | Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain.
Nat Commun, 11, 2020
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6SQR
 | | Crystal structure of Cat MDM2-S429E RING domain bound to UbcH5B-Ub | | Descriptor: | 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase Mdm2, NITRATE ION, ... | | Authors: | Magnussen, H.M, Ahmed, S.F, Huang, D.T. | | Deposit date: | 2019-09-04 | | Release date: | 2020-05-06 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.18 Å) | | Cite: | Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain.
Nat Commun, 11, 2020
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