1ITG
 
 | | CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HIV-1 INTEGRASE: SIMILARITY TO OTHER POLYNUCLEOTIDYL TRANSFERASES | | Descriptor: | CACODYLATE ION, HIV-1 INTEGRASE | | Authors: | Dyda, F, Hickman, A.B, Jenkins, T.M, Engelman, A, Craigie, R, Davies, D.R. | | Deposit date: | 1994-11-21 | | Release date: | 1995-05-08 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure of the catalytic domain of HIV-1 integrase: similarity to other polynucleotidyl transferases.
Science, 266, 1994
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9AZ7
 | | Chloride Sites in Photoactive Yellow Protein | | Descriptor: | 4'-HYDROXYCINNAMIC ACID, CHLORIDE ION, Photoactive yellow protein | | Authors: | Dyda, F, Schotte, F, Anfinrud, P, Cho, H.S. | | Deposit date: | 2024-03-10 | | Release date: | 2024-03-20 | | Last modified: | 2024-04-24 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Watching a signaling protein function: What has been learned over four decades of time-resolved studies of photoactive yellow protein.
Struct Dyn., 11, 2024
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9AZ9
 | | Chloride Sites in Photoactive Yellow Protein (Chloride-Free Reference Structure) | | Descriptor: | 4'-HYDROXYCINNAMIC ACID, Photoactive yellow protein | | Authors: | Dyda, F, Schotte, F, Anfinrud, P, Cho, H.S. | | Deposit date: | 2024-03-10 | | Release date: | 2024-03-20 | | Last modified: | 2024-04-24 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Watching a signaling protein function: What has been learned over four decades of time-resolved studies of photoactive yellow protein.
Struct Dyn., 11, 2024
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1PYD
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6DX0
 | | Hermes transposase deletion dimer complex with (A/T) DNA | | Descriptor: | DNA (25-MER), DNA (5'-D(*AP*GP*AP*GP*AP*AP*CP*AP*AP*CP*AP*AP*CP*AP*AP*G)-3'), DNA (5'-D(*GP*CP*GP*TP*GP*AP*A)-3'), ... | | Authors: | Dyda, F, Voth, A.R, Hickman, A.B. | | Deposit date: | 2018-06-28 | | Release date: | 2018-09-19 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structural insights into the mechanism of double strand break formation by Hermes, a hAT family eukaryotic DNA transposase.
Nucleic Acids Res., 46, 2018
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6DWW
 | | Hermes transposase deletion dimer complex with (A/T) DNA and Mn2+ | | Descriptor: | DNA (25-MER), DNA (5'-D(*AP*GP*AP*GP*AP*AP*CP*AP*AP*CP*AP*AP*CP*AP*AP*G)-3'), DNA (5'-D(*GP*CP*GP*TP*GP*AP*A)-3'), ... | | Authors: | Dyda, F, Voth, A.R, Hickman, A.B. | | Deposit date: | 2018-06-28 | | Release date: | 2018-09-19 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.851 Å) | | Cite: | Structural insights into the mechanism of double strand break formation by Hermes, a hAT family eukaryotic DNA transposase.
Nucleic Acids Res., 46, 2018
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6DWY
 | | Hermes transposase deletion dimer complex with (C/G) DNA and Ca2+ | | Descriptor: | CALCIUM ION, DNA (26-MER), DNA (5'-D(*AP*GP*AP*GP*AP*AP*CP*AP*AP*CP*AP*AP*CP*AP*AP*G)-3'), ... | | Authors: | Dyda, F, Hickman, A.B. | | Deposit date: | 2018-06-28 | | Release date: | 2018-09-19 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structural insights into the mechanism of double strand break formation by Hermes, a hAT family eukaryotic DNA transposase.
Nucleic Acids Res., 46, 2018
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6OPM
 | | Casposase bound to integration product | | Descriptor: | CALCIUM ION, CRISPR-associated endonuclease Cas1, DNA 21-mer, ... | | Authors: | Dyda, F, Hickman, A.B, Kailasan, S. | | Deposit date: | 2019-04-25 | | Release date: | 2020-02-12 | | Last modified: | 2020-08-26 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Casposase structure and the mechanistic link between DNA transposition and spacer acquisition by CRISPR-Cas.
Elife, 9, 2020
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6B67
 | | Human PP2Calpha (PPM1A) complexed with cyclic peptide c(MpSIpYVA) | | Descriptor: | CALCIUM ION, Protein phosphatase 1A, cyclic peptide c(MpSIpYVA) | | Authors: | Dyda, F, Kosek, D. | | Deposit date: | 2017-10-01 | | Release date: | 2018-04-11 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | A trapped human PPM1A-phosphopeptide complex reveals structural features critical for regulation of PPM protein phosphatase activity.
J. Biol. Chem., 293, 2018
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6DWZ
 | | Hermes transposase deletion dimer complex with (C/G) DNA | | Descriptor: | DNA (26-MER), DNA (5'-D(*GP*AP*GP*AP*AP*CP*AP*AP*CP*AP*AP*CP*AP*AP*G)-3'), DNA (5'-D(*GP*CP*GP*TP*GP*AP*C)-3'), ... | | Authors: | Dyda, F, Hickman, A.B. | | Deposit date: | 2018-06-28 | | Release date: | 2018-09-19 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structural insights into the mechanism of double strand break formation by Hermes, a hAT family eukaryotic DNA transposase.
Nucleic Acids Res., 46, 2018
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1UUT
 | | The Nuclease Domain of Adeno-Associated Virus Rep Complexed with the RBE' Stemloop of the Viral Inverted Terminal Repeat | | Descriptor: | 5'-D(*CP*AP*GP*CP*TP*CP*TP*TP*TP*GP *AP*GP*CP*TP*G)-3', CHLORIDE ION, MAGNESIUM ION, ... | | Authors: | Dyda, F, Hickman, A.B, Ronning, D.R, Perez, Z.N, Kotin, R.M. | | Deposit date: | 2004-01-10 | | Release date: | 2004-02-19 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The Nuclease Domain of Adeno-Associated Virus Rep Coordinates Replication Initiation Using Two Distinct DNA Recognition Interfaces
Mol.Cell, 13, 2004
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8T2J
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1F1Z
 | | TNSA, a catalytic component of the TN7 transposition system | | Descriptor: | CHLORIDE ION, MAGNESIUM ION, TNSA ENDONUCLEASE | | Authors: | Hickman, A.B, Li, Y, Mathew, S.V, May, E.W, Craig, N.L, Dyda, F. | | Deposit date: | 2000-05-21 | | Release date: | 2000-06-28 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Unexpected structural diversity in DNA recombination: the restriction endonuclease connection.
Mol.Cell, 5, 2000
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1MVK
 | | X-ray structure of the tetrameric mutant of the B1 domain of streptococcal protein G | | Descriptor: | Immunoglobulin G binding protein G, SULFATE ION | | Authors: | Frank, M.K, Dyda, F, Dobrodumov, A, Gronenborn, A.M. | | Deposit date: | 2002-09-25 | | Release date: | 2002-10-30 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Core mutations switch monomeric protein GB1 into an intertwined tetramer.
Nat.Struct.Biol., 9, 2002
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4ER8
 | | Structure of the REP associates tyrosine transposase bound to a REP hairpin | | Descriptor: | DNA (32-MER), NICKEL (II) ION, TnpArep for protein | | Authors: | Messing, S.A.J, Ton-Hoang, B, Hickman, A.B, Ghirlando, R, Chandler, M, Dyda, F. | | Deposit date: | 2012-04-19 | | Release date: | 2012-08-15 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | The processing of repetitive extragenic palindromes: the structure of a repetitive extragenic palindrome bound to its associated nuclease.
Nucleic Acids Res., 40, 2012
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7TH0
 | | Escherichia coli RpnA-S | | Descriptor: | Recombination-promoting nuclease RpnA | | Authors: | Zhong, A, Hickman, A.B, Storz, G, Dyda, F. | | Deposit date: | 2022-01-10 | | Release date: | 2023-03-29 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Toxic antiphage defense proteins inhibited by intragenic antitoxin proteins.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8SJD
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8EDG
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8EB5
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6X68
 | | Cryo-EM structure of piggyBac transposase synaptic complex with hairpin DNA (SNHP) | | Descriptor: | CALCIUM ION, Transposase, ZINC ION, ... | | Authors: | Chen, Q, Hickman, A.B, Dyda, F. | | Deposit date: | 2020-05-27 | | Release date: | 2020-07-22 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.66 Å) | | Cite: | Structural basis of seamless excision and specific targeting by piggyBac transposase
Nat Commun, 11, 2020
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6XG8
 | | ISCth4 transposase, pre-cleaved complex, PCC | | Descriptor: | DNA (26-MER), Mutator family transposase | | Authors: | Kosek, D, Dyda, F. | | Deposit date: | 2020-06-17 | | Release date: | 2020-10-14 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Structures of ISCth4 transpososomes reveal the role of asymmetry in copy-out/paste-in DNA transposition.
Embo J., 40, 2021
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6XGW
 | | ISCth4 transposase, pre-reaction complex, PRC | | Descriptor: | DNA (32-MER), Mutator family transposase | | Authors: | Kosek, D, Dyda, F. | | Deposit date: | 2020-06-18 | | Release date: | 2020-10-14 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Structures of ISCth4 transpososomes reveal the role of asymmetry in copy-out/paste-in DNA transposition.
Embo J., 40, 2021
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6X67
 | | Cryo-EM structure of piggyBac transposase strand transfer complex (STC) | | Descriptor: | CALCIUM ION, DNA (37-MER), DNA (47-MER), ... | | Authors: | Chen, Q, Hickman, A.B, Dyda, F. | | Deposit date: | 2020-05-27 | | Release date: | 2020-07-22 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.47 Å) | | Cite: | Structural basis of seamless excision and specific targeting by piggyBac transposase
Nat Commun, 11, 2020
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6XGX
 | | ISCth4 transposase, strand transfer complex 1, STC1 | | Descriptor: | DNA (21-MER), DNA (25-MER), DNA (47-MER), ... | | Authors: | Kosek, D, Dyda, F. | | Deposit date: | 2020-06-18 | | Release date: | 2020-10-14 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Structures of ISCth4 transpososomes reveal the role of asymmetry in copy-out/paste-in DNA transposition.
Embo J., 40, 2021
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5LME
 | | Specific-DNA binding activity of the cross-brace zinc finger motif of the piggyBac transposase | | Descriptor: | ZINC ION, piggyBac transposase | | Authors: | Morellet, N, Taylor, J.A, Wieninger, S, Moriau, S, Li, X, Lescop, E, Mathy, N, Bischerour, J, Betermier, M, Bardiaux, B, Nilges, M, Craig, N.L, Hickman, A.B, Dyda, F, Guittet, E. | | Deposit date: | 2016-07-30 | | Release date: | 2017-12-20 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Sequence-specific DNA binding activity of the cross-brace zinc finger motif of the piggyBac transposase.
Nucleic Acids Res., 46, 2018
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