1ASZ
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![BU of 1asz by Molmil](/molmil-images/mine/1asz) | THE ACTIVE SITE OF YEAST ASPARTYL-TRNA SYNTHETASE: STRUCTURAL AND FUNCTIONAL ASPECTS OF THE AMINOACYLATION REACTION | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, ASPARTYL-tRNA SYNTHETASE, T-RNA (75-MER) | Authors: | Cavarelli, J, Rees, B, Thierry, J.C, Moras, D. | Deposit date: | 1995-01-19 | Release date: | 1995-05-08 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The active site of yeast aspartyl-tRNA synthetase: structural and functional aspects of the aminoacylation reaction. EMBO J., 13, 1994
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1BS2
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![BU of 1bs2 by Molmil](/molmil-images/mine/1bs2) | YEAST ARGINYL-TRNA SYNTHETASE | Descriptor: | ARGININE, PROTEIN (ARGINYL-TRNA SYNTHETASE) | Authors: | Cavarelli, J, Delagouute, B, Eriani, G, Gangloff, J, Moras, D. | Deposit date: | 1998-08-31 | Release date: | 1999-08-27 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | L-arginine recognition by yeast arginyl-tRNA synthetase. EMBO J., 17, 1998
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1AGJ
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![BU of 1agj by Molmil](/molmil-images/mine/1agj) | EPIDERMOLYTIC TOXIN A FROM STAPHYLOCOCCUS AUREUS | Descriptor: | EPIDERMOLYTIC TOXIN A | Authors: | Cavarelli, J. | Deposit date: | 1997-03-25 | Release date: | 1997-09-26 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The structure of Staphylococcus aureus epidermolytic toxin A, an atypic serine protease, at 1.7 A resolution. Structure, 5, 1997
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1YZ1
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![BU of 1yz1 by Molmil](/molmil-images/mine/1yz1) | |
3PY7
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![BU of 3py7 by Molmil](/molmil-images/mine/3py7) | |
2OQB
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![BU of 2oqb by Molmil](/molmil-images/mine/2oqb) | |
2XPN
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![BU of 2xpn by Molmil](/molmil-images/mine/2xpn) | Crystal structure of a Spt6-Iws1(Spn1) complex from Encephalitozoon cuniculi, Form I | Descriptor: | BROMIDE ION, CHROMATIN STRUCTURE MODULATOR, IWS1 | Authors: | Diebold, M.-L, Koch, M, Cura, V, Cavarelli, J, Romier, C. | Deposit date: | 2010-08-27 | Release date: | 2010-11-17 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | The Structure of an Iws1/Spt6 Complex Reveals an Interaction Domain Conserved in Tfiis, Elongin a and Med26 Embo J., 29, 2010
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2XPO
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![BU of 2xpo by Molmil](/molmil-images/mine/2xpo) | Crystal structure of a Spt6-Iws1(Spn1) complex from Encephalitozoon cuniculi, Form II | Descriptor: | CHLORIDE ION, CHROMATIN STRUCTURE MODULATOR, IWS1 | Authors: | Diebold, M.-L, Koch, M, Cura, V, Moras, D, Cavarelli, J, Romier, C. | Deposit date: | 2010-08-27 | Release date: | 2010-11-17 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The Structure of an Iws1/Spt6 Complex Reveals an Interaction Domain Conserved in Tfiis, Elongin a and Med26 Embo J., 29, 2010
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5K8V
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![BU of 5k8v by Molmil](/molmil-images/mine/5k8v) | Crystal Structure of Mus musculus Protein Arginine Methyltransferase 4 (CARM1 130-487) with CP1 | Descriptor: | 1,2-DIMETHOXYETHANE, 1,2-ETHANEDIOL, 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, ... | Authors: | Cura, V, Marechal, N, Mailliot, J, Troffer-Charlier, N, Hassenboehler, P, Wurtz, J.M, Bonnefond, L, Cavarelli, J. | Deposit date: | 2016-05-31 | Release date: | 2016-11-09 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structural studies of protein arginine methyltransferase 2 reveal its interactions with potential substrates and inhibitors. FEBS J., 284, 2017
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7QRD
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![BU of 7qrd by Molmil](/molmil-images/mine/7qrd) | Crystal structure of mouse CARM1 in complex with histone H3_10-25 | Descriptor: | (2~{R},3~{R},4~{S},5~{R})-2-(6-aminopurin-9-yl)-5-[(~{E})-prop-1-enyl]oxolane-3,4-diol, 1,2-ETHANEDIOL, Histone-arginine methyltransferase CARM1, ... | Authors: | Marechal, N, Cura, V, Troffer-Charlier, N, Bonnefond, L, Cavarelli, J. | Deposit date: | 2022-01-11 | Release date: | 2022-12-28 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | CARM1 Transition State Mimics To Be Published
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7QPH
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![BU of 7qph by Molmil](/molmil-images/mine/7qph) | Crystal structure of mouse CARM1 in complex with histone H3_22-31 K27 acetylated | Descriptor: | (2~{R},3~{R},4~{S},5~{R})-2-(6-aminopurin-9-yl)-5-[(~{E})-prop-1-enyl]oxolane-3,4-diol, 1,2-ETHANEDIOL, Histone H3 22-31 K27 acetylated, ... | Authors: | Marechal, N, Cura, V, Troffer-Charlier, N, Bonnefond, L, Cavarelli, J. | Deposit date: | 2022-01-04 | Release date: | 2023-01-18 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | CARM1 Transition State Mimics To Be Published
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5K8X
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![BU of 5k8x by Molmil](/molmil-images/mine/5k8x) | Crystal structure of mouse CARM1 in complex with inhibitor U3 | Descriptor: | 1,2-DIMETHOXYETHANE, 1,2-ETHANEDIOL, 1-METHOXY-2-(2-METHOXYETHOXY)ETHANE, ... | Authors: | Cura, V, Marechal, N, Mailliot, J, Troffer-Charlier, N, Hassenboehler, P, Wurtz, J.M, Bonnefond, L, Cavarelli, J. | Deposit date: | 2016-05-31 | Release date: | 2017-06-21 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.991 Å) | Cite: | Crystal structure of mouse CARM1 in complex with inhibitor U3 To Be Published
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1EOV
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![BU of 1eov by Molmil](/molmil-images/mine/1eov) | FREE ASPARTYL-TRNA SYNTHETASE (ASPRS) (E.C. 6.1.1.12) FROM YEAST | Descriptor: | ASPARTYL-TRNA SYNTHETASE | Authors: | Sauter, C, Lorber, B, Cavarelli, J, Moras, D, Giege, R. | Deposit date: | 2000-03-24 | Release date: | 2000-09-24 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The free yeast aspartyl-tRNA synthetase differs from the tRNA(Asp)-complexed enzyme by structural changes in the catalytic site, hinge region, and anticodon-binding domain. J.Mol.Biol., 299, 2000
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3O0A
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![BU of 3o0a by Molmil](/molmil-images/mine/3o0a) | Crystal structure of the wild type CP1 hydrolitic domain from Aquifex Aeolicus leucyl-trna | Descriptor: | Leucyl-tRNA synthetase subunit alpha | Authors: | Cura, V, Olieric, N, Wang, E.-D, Moras, D, Eriani, G, Cavarelli, J. | Deposit date: | 2010-07-19 | Release date: | 2010-11-17 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Crystal Structure of the Wild Type and Two Mutants of the Cp1 Hydrolytic Domain from Aquifex Aeolicus Leucyl-tRNA Synthetase To be Published
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4X33
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![BU of 4x33 by Molmil](/molmil-images/mine/4x33) | Structure of the Elongator cofactor complex Kti11/Kti13 at 1.45A | Descriptor: | 1,2-DIMETHOXYETHANE, CHLORIDE ION, Diphthamide biosynthesis protein 3, ... | Authors: | Kolaj-Robin, O, McEwen, A.G, Cavarelli, J, Seraphin, B. | Deposit date: | 2014-11-27 | Release date: | 2015-01-21 | Last modified: | 2015-03-11 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structure of the Elongator cofactor complex Kti11/Kti13 provides insight into the role of Kti13 in Elongator-dependent tRNA modification. Febs J., 282, 2015
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4Z9V
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![BU of 4z9v by Molmil](/molmil-images/mine/4z9v) | TCTP contains a BH3-like domain, which instead of inhibiting, activates Bcl-xL | Descriptor: | BICARBONATE ION, Bcl-2-like protein 1,APOPTOSIS REGULATOR BCL-XL, SODIUM ION, ... | Authors: | Cura, V, Agez, M, Thebault, S, Cavarelli, J. | Deposit date: | 2015-04-12 | Release date: | 2016-02-10 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.099 Å) | Cite: | TCTP contains a BH3-like domain, which instead of inhibiting, activates Bcl-xL. Sci Rep, 6, 2016
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3B3G
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![BU of 3b3g by Molmil](/molmil-images/mine/3b3g) | The 2.4 A crystal structure of the apo catalytic domain of coactivator-associated arginine methyl transferase I(CARM1,140-480). | Descriptor: | Histone-arginine methyltransferase CARM1 | Authors: | Troffer-Charlier, N, Cura, V, Hassenboehler, P, Moras, D, Cavarelli, J. | Deposit date: | 2007-10-22 | Release date: | 2007-11-06 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Functional insights from structures of coactivator-associated arginine methyltransferase 1 domains. Embo J., 26, 2007
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3B3F
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![BU of 3b3f by Molmil](/molmil-images/mine/3b3f) | The 2.2 A crystal structure of the catalytic domain of coactivator-associated arginine methyl transferase I(CARM1,142-478), in complex with S-adenosyl homocysteine | Descriptor: | Histone-arginine methyltransferase CARM1, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Troffer-Charlier, N, Cura, V, Hassenboehler, P, Moras, D, Cavarelli, J. | Deposit date: | 2007-10-22 | Release date: | 2007-11-06 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Functional insights from structures of coactivator-associated arginine methyltransferase 1 domains. Embo J., 26, 2007
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3B3J
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![BU of 3b3j by Molmil](/molmil-images/mine/3b3j) | The 2.55 A crystal structure of the apo catalytic domain of coactivator-associated arginine methyl transferase I(CARM1:28-507, residues 28-146 and 479-507 not ordered) | Descriptor: | BENZAMIDINE, Histone-arginine methyltransferase CARM1 | Authors: | Troffer-Charlier, N, Cura, V, Hassenboehler, P, Moras, D, Cavarelli, J. | Deposit date: | 2007-10-22 | Release date: | 2007-11-06 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Functional insights from structures of coactivator-associated arginine methyltransferase 1 domains. Embo J., 26, 2007
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8BVA
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![BU of 8bva by Molmil](/molmil-images/mine/8bva) | Crystal Structure of Mus musculus Protein Arginine Methyltransferase 2 in complex with RSF1_114-126 | Descriptor: | (2~{R},3~{R},4~{S},5~{R})-2-(6-aminopurin-9-yl)-5-[(~{E})-prop-1-enyl]oxolane-3,4-diol, L(+)-TARTARIC ACID, POTASSIUM ION, ... | Authors: | Cura, V, Troffer-Charlier, N, Marechal, N, Bonnefond, L, Cavarelli, J. | Deposit date: | 2022-12-02 | Release date: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | Crystal Structure of Mus musculus Protein Arginine Methyltransferase 2 in complex with RSF1_114-126 To Be Published
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8C1J
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![BU of 8c1j by Molmil](/molmil-images/mine/8c1j) | Crystal Structure of Mus musculus Protein Arginine Methyltransferase 2 in complex with RSF1_18-30 | Descriptor: | (2~{R},3~{R},4~{S},5~{R})-2-(6-aminopurin-9-yl)-5-[(~{E})-prop-1-enyl]oxolane-3,4-diol, Protein arginine N-methyltransferase 2, RNA-binding protein Rsf1-like | Authors: | Cura, V, Troffer-Charlier, N, Marechal, N, Bonnefond, L, Cavarelli, J. | Deposit date: | 2022-12-20 | Release date: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of Mus musculus Protein Arginine Methyltransferase 2 in complex with RSF1_18-30 To Be Published
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1JMM
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![BU of 1jmm by Molmil](/molmil-images/mine/1jmm) | Crystal structure of the V-region of Streptococcus mutans antigen I/II | Descriptor: | SODIUM ION, protein I/II V-region | Authors: | Troffer-Charlier, N, Ogier, J, Moras, D, Cavarelli, J. | Deposit date: | 2001-07-19 | Release date: | 2002-07-17 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal Structure of the V-region of Streptococcus mutans Antigen I/II at 2.4 a Resolution Suggests a Sugar Preformed Binding Site J.Mol.Biol., 318, 2002
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2XPL
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![BU of 2xpl by Molmil](/molmil-images/mine/2xpl) | Crystal structure of Iws1(Spn1) conserved domain from Encephalitozoon cuniculi | Descriptor: | CHLORIDE ION, IWS1 | Authors: | Koch, M, Diebold, M.-L, Cura, V, Cavarelli, J, Romier, C. | Deposit date: | 2010-08-27 | Release date: | 2010-11-17 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | The Structure of an Iws1/Spt6 Complex Reveals an Interaction Domain Conserved in Tfiis, Elongin a and Med26 Embo J., 29, 2010
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2QEN
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![BU of 2qen by Molmil](/molmil-images/mine/2qen) | The walker-type atpase paby2304 of pyrococcus abyssi | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, WALKER-TYPE ATPASE | Authors: | Uhring, M, Bey, G, Lecompte, O, Moras, D, Poch, O, Cavarelli, J. | Deposit date: | 2007-06-26 | Release date: | 2008-07-01 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | The walker-type atpase paby2304 of pyrococcus abyssi To be Published
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5NTC
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![BU of 5ntc by Molmil](/molmil-images/mine/5ntc) | Crystal structure of mouse CARM1 in complex with inhibitor SA0678 | Descriptor: | 1,2-DIMETHOXYETHANE, 1,2-ETHANEDIOL, 1-METHOXY-2-(2-METHOXYETHOXY)ETHANE, ... | Authors: | Cura, V, Marechal, N, Mailliot, J, Troffer-Charlier, N, Hassenboehler, P, Wurtz, J.M, Bonnefond, L, Cavarelli, J. | Deposit date: | 2017-04-27 | Release date: | 2018-05-30 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Crystal structure of mouse CARM1 in complex with inhibitor SA0678 To Be Published
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