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8Q9Z
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BU of 8q9z by Molmil
Cryo-EM structure of Cx26 gap junction K125E mutant in bicarbonate buffer (classification on hemichannel)
Descriptor: DODECYL-BETA-D-MALTOSIDE, Gap junction beta-2 protein, PHOSPHATIDYLETHANOLAMINE
Authors:Brotherton, D.H, Cameron, A.D.
Deposit date:2023-08-22
Release date:2024-06-12
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Structures of wild-type and a constitutively closed mutant of connexin26 shed light on channel regulation by CO 2.
Elife, 13, 2024
8QA1
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BU of 8qa1 by Molmil
Cryo-EM structure of Cx26 solubilised in LMNG - Hemichannel classification NFlex conformation
Descriptor: Gap junction beta-2 protein, PHOSPHATIDYLETHANOLAMINE
Authors:Brotherton, D.H, Cameron, A.D.
Deposit date:2023-08-22
Release date:2024-06-12
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Structures of wild-type and a constitutively closed mutant of connexin26 shed light on channel regulation by CO 2.
Elife, 13, 2024
8QA2
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BU of 8qa2 by Molmil
Cryo-EM structure of Cx26 solubilised in LMNG: classification on subunit A; Nconst-mon conformation
Descriptor: Gap junction beta-2 protein, PHOSPHATIDYLETHANOLAMINE
Authors:Brotherton, D.H, Cameron, A.D.
Deposit date:2023-08-22
Release date:2024-06-12
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Structures of wild-type and a constitutively closed mutant of connexin26 shed light on channel regulation by CO 2.
Elife, 13, 2024
8QA3
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BU of 8qa3 by Molmil
Cryo-EM structure of Cx26 solubilised in LMNG: classification on subunit A; NFlex conformation
Descriptor: Gap junction beta-2 protein, PHOSPHATIDYLETHANOLAMINE
Authors:Brotherton, D.H, Cameron, A.D.
Deposit date:2023-08-22
Release date:2024-06-12
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Structures of wild-type and a constitutively closed mutant of connexin26 shed light on channel regulation by CO 2.
Elife, 13, 2024
8QA0
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BU of 8qa0 by Molmil
Cryo-EM structure of Cx26 solubilised in LMNG - hemichannel classification - NConst conformation
Descriptor: Gap junction beta-2 protein, PHOSPHATIDYLETHANOLAMINE
Authors:Brotherton, D.H, Cameron, A.D.
Deposit date:2023-08-22
Release date:2024-06-12
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Structures of wild-type and a constitutively closed mutant of connexin26 shed light on channel regulation by CO 2.
Elife, 13, 2024
7QEQ
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BU of 7qeq by Molmil
human Connexin 26 dodecamer at 90mmHg PCO2, pH7.4
Descriptor: DODECYL-BETA-D-MALTOSIDE, Gap junction beta-2 protein, PHOSPHATIDYLETHANOLAMINE
Authors:Brotherton, D.H, Cameron, A.D, Savva, C.G, Ragan, T.J.
Deposit date:2021-12-03
Release date:2022-03-30
Last modified:2022-05-18
Method:ELECTRON MICROSCOPY (1.9 Å)
Cite:Conformational changes and CO 2 -induced channel gating in connexin26.
Structure, 30, 2022
7QER
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BU of 7qer by Molmil
human Connexin 26 dodecamer at 55mm Hg PCO2, pH7.4
Descriptor: DODECYL-BETA-D-MALTOSIDE, Gap junction beta-2 protein, PHOSPHATIDYLETHANOLAMINE
Authors:Brotherton, D.H, Cameron, A.D, Savva, C.G, Ragan, T.J.
Deposit date:2021-12-03
Release date:2022-03-30
Last modified:2022-05-18
Method:ELECTRON MICROSCOPY (2.2 Å)
Cite:Conformational changes and CO 2 -induced channel gating in connexin26.
Structure, 30, 2022
7QEW
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BU of 7qew by Molmil
human Connexin 26 class 2 hexamer at 90mmHg PCO2, pH7.4
Descriptor: DODECYL-BETA-D-MALTOSIDE, Gap junction beta-2 protein, PHOSPHATIDYLETHANOLAMINE
Authors:Brotherton, D.H, Cameron, A.D, Savva, C.G, Ragan, T.J.
Deposit date:2021-12-03
Release date:2022-03-30
Last modified:2022-05-18
Method:ELECTRON MICROSCOPY (2.1 Å)
Cite:Conformational changes and CO 2 -induced channel gating in connexin26.
Structure, 30, 2022
7QET
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BU of 7qet by Molmil
human Connexin 26 dodecamer at 20mmHg PCO2, pH7.4
Descriptor: DODECYL-BETA-D-MALTOSIDE, Gap junction beta-2 protein, PHOSPHATIDYLETHANOLAMINE
Authors:Brotherton, D.H, Cameron, A.D, Savva, C.G, Ragan, T.J.
Deposit date:2021-12-03
Release date:2022-03-30
Last modified:2022-05-18
Method:ELECTRON MICROSCOPY (2.1 Å)
Cite:Conformational changes and CO 2 -induced channel gating in connexin26.
Structure, 30, 2022
7QEY
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BU of 7qey by Molmil
human Connexin 26 class 1 hexamer at 90mmHg PCO2, pH7.4
Descriptor: DODECYL-BETA-D-MALTOSIDE, Gap junction beta-2 protein, PHOSPHATIDYLETHANOLAMINE
Authors:Brotherton, D.H, Cameron, A.D, Savva, C.G, Ragan, T.J.
Deposit date:2021-12-03
Release date:2022-03-30
Last modified:2022-11-09
Method:ELECTRON MICROSCOPY (2 Å)
Cite:Conformational changes and CO 2 -induced channel gating in connexin26.
Structure, 30, 2022
7QEU
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BU of 7qeu by Molmil
human Connexin 26 at 55mmHg PCO2, pH7.4: two masked subunits, class B
Descriptor: DODECYL-BETA-D-MALTOSIDE, Gap junction beta-2 protein, PHOSPHATIDYLETHANOLAMINE
Authors:Brotherton, D.H, Cameron, A.D, Savva, C.G, Ragan, T.J.
Deposit date:2021-12-03
Release date:2022-06-15
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Conformational changes and CO 2 -induced channel gating in connexin26.
Structure, 30, 2022
7QEO
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BU of 7qeo by Molmil
human Connexin 26 at 55mm Hg PCO2, pH7.4: two masked subunits, class C
Descriptor: DODECYL-BETA-D-MALTOSIDE, Gap junction beta-2 protein, PHOSPHATIDYLETHANOLAMINE
Authors:Brotherton, D.H, Cameron, A.D, Savva, C.G, Ragan, T.J.
Deposit date:2021-12-03
Release date:2022-06-22
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Conformational changes and CO 2 -induced channel gating in connexin26.
Structure, 30, 2022
7QEV
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BU of 7qev by Molmil
human Connexin 26 at 55mm Hg PCO2, pH7.4:two masked subunits, class D
Descriptor: DODECYL-BETA-D-MALTOSIDE, Gap junction beta-2 protein, PHOSPHATIDYLETHANOLAMINE
Authors:Brotherton, D.H, Cameron, A.D, Savva, C.G, Ragan, T.J.
Deposit date:2021-12-03
Release date:2022-06-15
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Conformational changes and CO 2 -induced channel gating in connexin26.
Structure, 30, 2022
7QES
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BU of 7qes by Molmil
human Connexin 26 at 55mm Hg PCO2, pH7.4: two masked subunits, class A
Descriptor: DODECYL-BETA-D-MALTOSIDE, Gap junction beta-2 protein, PHOSPHATIDYLETHANOLAMINE
Authors:Brotherton, D.H, Cameron, A.D, Savva, C.G, Ragan, T.J.
Deposit date:2021-12-03
Release date:2022-06-15
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Conformational changes and CO 2 -induced channel gating in connexin26.
Structure, 30, 2022
1BLX
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BU of 1blx by Molmil
P19INK4D/CDK6 COMPLEX
Descriptor: CALCIUM ION, CYCLIN-DEPENDENT KINASE 6, P19INK4D
Authors:Brotherton, D.H, Dhanaraj, V, Wick, S, Brizuela, L, Domaille, P.J, Volyanik, E, Xu, X, Parisini, E, Smith, B.O, Archer, S.J, Serrano, M, Brenner, S.L, Blundell, T.L, Laue, E.D.
Deposit date:1998-07-21
Release date:1999-06-01
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the complex of the cyclin D-dependent kinase Cdk6 bound to the cell-cycle inhibitor p19INK4d.
Nature, 395, 1998
8OYG
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BU of 8oyg by Molmil
Crystal structure of ASBTNM in complex with pantoate
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CADMIUM ION, PANTOATE, ...
Authors:Becker, P, Cameron, A.D.
Deposit date:2023-05-04
Release date:2023-07-12
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Mechanism of substrate binding and transport in BASS transporters.
Biorxiv, 2023
8OYF
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BU of 8oyf by Molmil
Crystal structure of ASBTNM in lipidic cubic phase without substrate bound
Descriptor: (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, NICKEL (II) ION, PHOSPHATIDYLETHANOLAMINE, ...
Authors:Becker, P, Cameron, A.D.
Deposit date:2023-05-04
Release date:2023-07-12
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Mechanism of substrate binding and transport in BASS transporters.
Biorxiv, 2023
7QOA
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BU of 7qoa by Molmil
Structure of CodB, a cytosine transporter in an outward-facing conformation
Descriptor: 2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 6-AMINOPYRIMIDIN-2(1H)-ONE, Cytosine permease, ...
Authors:Hatton, C.E, Cameron, A.D.
Deposit date:2021-12-23
Release date:2022-07-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of cytosine transport protein CodB provides insight into nucleobase-cation symporter 1 mechanism.
Embo J., 41, 2022
1AP7
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BU of 1ap7 by Molmil
P19-INK4D FROM MOUSE, NMR, 20 STRUCTURES
Descriptor: P19-INK4D
Authors:Archer, S.J, Luh, F.Y, Domaille, P.J, Smith, B.O, Laue, E.D.
Deposit date:1997-07-25
Release date:1998-09-16
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure of the cyclin-dependent kinase inhibitor p19Ink4d.
Nature, 389, 1997

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數據於2024-07-31公開中

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