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human cardiac myosin binding protein C C1 Ig-domain bound to native cardiac thin filament
Descriptor:	Actin, cytoplasmic 2, Myosin-binding protein C, ...
Authors:	Risi, C, Belknap, B, Forgacs, E, Harris, S.P, Schroder, G.F, White, H.D, Galkin, V.E.
Deposit date:	2018-03-23
Release date:	2018-10-17
Last modified:	2024-05-15
Method:	ELECTRON MICROSCOPY (9 Å)
Cite:	N-Terminal Domains of Cardiac Myosin Binding Protein C Cooperatively Activate the Thin Filament. Structure, 26, 2018

5NOG

Ca2+-induced Movement of Tropomyosin on Native Cardiac Thin Filaments - "Blocked" state
Descriptor:	ADENOSINE-5'-DIPHOSPHATE, Cardiac muscle alpha actin 1, MAGNESIUM ION, ...
Authors:	Risi, C, Eisner, J, Belknap, B, Heeley, D.H, White, H.D, Schroeder, G.F, Galkin, V.E.
Deposit date:	2017-04-12
Release date:	2017-07-19
Last modified:	2017-08-30
Method:	ELECTRON MICROSCOPY (11 Å)
Cite:	Ca(2+)-induced movement of tropomyosin on native cardiac thin filaments revealed by cryoelectron microscopy. Proc. Natl. Acad. Sci. U.S.A., 114, 2017

5NOL

Ca2+-induced Movement of Tropomyosin on Native Cardiac Thin Filaments - "Closed" state
Descriptor:	ADENOSINE-5'-DIPHOSPHATE, Cardiac muscle alpha actin 1, MAGNESIUM ION, ...
Authors:	Risi, C, Eisner, J, Belknap, B, Heeley, D.H, White, H.D, Schroeder, G.F, Galkin, V.E.
Deposit date:	2017-04-12
Release date:	2017-07-19
Last modified:	2024-05-15
Method:	ELECTRON MICROSCOPY (8 Å)
Cite:	Ca(2+)-induced movement of tropomyosin on native cardiac thin filaments revealed by cryoelectron microscopy. Proc. Natl. Acad. Sci. U.S.A., 114, 2017

5NOJ

Ca2+-induced Movement of Tropomyosin on Native Cardiac Thin Filaments - "OPEN" state
Descriptor:	ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:	Risi, C, Eisner, J, Belknap, B, Heeley, D.H, White, H.D, Schroeder, G.F, Galkin, V.E.
Deposit date:	2017-04-12
Release date:	2017-08-02
Last modified:	2017-08-09
Method:	ELECTRON MICROSCOPY (11 Å)
Cite:	Ca(2+)-induced movement of tropomyosin on native cardiac thin filaments revealed by cryoelectron microscopy. Proc. Natl. Acad. Sci. U.S.A., 114, 2017

8DD0

The structure of the native cardiac thin filament junction region
Descriptor:	ADENOSINE-5'-DIPHOSPHATE, Actin, alpha cardiac muscle 1, ...
Authors:	Galkin, V.E, Risi, C.M.
Deposit date:	2022-06-17
Release date:	2022-12-28
Last modified:	2024-06-12
Method:	ELECTRON MICROSCOPY (3.5 Å)
Cite:	High-resolution cryo-EM structure of the junction region of the native cardiac thin filament in relaxed state. Pnas Nexus, 2, 2023

7LRG

Filamentous actin decorated with human cardiac myosin binding protein C C2 domain
Descriptor:	Actin, alpha cardiac muscle 1, Myosin-binding protein C, ...
Authors:	Galkin, V.E.
Deposit date:	2021-02-16
Release date:	2021-08-11
Last modified:	2024-05-29
Method:	ELECTRON MICROSCOPY (6.1 Å)
Cite:	Interaction of the C2 Ig-like Domain of Cardiac Myosin Binding Protein-C with F-actin. J.Mol.Biol., 433, 2021

6CXI

Cardiac thin filament decorated with C0C1 fragment of cardiac myosin binding protein C mode 1
Descriptor:	Actin, cytoplasmic 2, Myosin-binding protein C, ...
Authors:	Galkin, V.E, Schroeder, G.F.
Deposit date:	2018-04-03
Release date:	2018-10-10
Last modified:	2024-03-13
Method:	ELECTRON MICROSCOPY (11 Å)
Cite:	N-Terminal Domains of Cardiac Myosin Binding Protein C Cooperatively Activate the Thin Filament. Structure, 26, 2018

6CXJ

Cardiac thin filament decorated with C0C1 fragment of cardiac myosin binding protein C mode 2
Descriptor:	Actin, cytoplasmic 2, Myosin-binding protein C, ...
Authors:	Galkin, V.E, Schroeder, G.F.
Deposit date:	2018-04-03
Release date:	2018-10-10
Last modified:	2024-03-13
Method:	ELECTRON MICROSCOPY (11 Å)
Cite:	N-Terminal Domains of Cardiac Myosin Binding Protein C Cooperatively Activate the Thin Filament. Structure, 26, 2018

7TIT

Cardiac thin filament decorated with regulatory M-domain of cardiac myosin binding protein C
Descriptor:	Myosin-binding protein C, cardiac-type, cardiac actin, ...
Authors:	Risi, C.M, Galkin, V.E.
Deposit date:	2022-01-14
Release date:	2022-11-23
Last modified:	2024-06-05
Method:	ELECTRON MICROSCOPY (8 Å)
Cite:	Cryo-Electron Microscopy Reveals Cardiac Myosin Binding Protein-C M-Domain Interactions with the Thin Filament. J.Mol.Biol., 434, 2022

7TJ7

Cardiac thin filament decorated with C1 Ig-domain and regulatory M-domain of cardiac myosin binding protein C (cMyBP-C)
Descriptor:	Myosin-binding protein C, cardiac-type, cardiac actin, ...
Authors:	Risi, C.M, Galkin, V.E.
Deposit date:	2022-01-14
Release date:	2022-11-23
Last modified:	2024-06-05
Method:	ELECTRON MICROSCOPY (8 Å)
Cite:	Cryo-Electron Microscopy Reveals Cardiac Myosin Binding Protein-C M-Domain Interactions with the Thin Filament. J.Mol.Biol., 434, 2022

7TIJ

Cardiac F-actin decorated with regulatory M-domain of cardiac myosin binding protein C
Descriptor:	Myosin-binding protein C, cardiac-type, cardiac actin
Authors:	Risi, C.M, Galkin, V.E.
Deposit date:	2022-01-13
Release date:	2022-11-23
Last modified:	2024-06-05
Method:	ELECTRON MICROSCOPY (8 Å)
Cite:	Cryo-Electron Microscopy Reveals Cardiac Myosin Binding Protein-C M-Domain Interactions with the Thin Filament. J.Mol.Biol., 434, 2022

7JH7

cardiac actomyosin complex
Descriptor:	ADENOSINE-5'-DIPHOSPHATE, Actin, alpha cardiac muscle 1, ...
Authors:	Galkin, V.E, Schroeder, G.F.
Deposit date:	2020-07-20
Release date:	2020-10-28
Last modified:	2024-03-06
Method:	ELECTRON MICROSCOPY (3.8 Å)
Cite:	High-Resolution Cryo-EM Structure of the Cardiac Actomyosin Complex. Structure, 29, 2021

7KO4

Structure of cardiac native thin filament at pCa=5.8 having upper and lower troponins in Ca2+ free state
Descriptor:	Actin, alpha skeletal muscle, Isoform 4 of Troponin T, ...
Authors:	Galkin, V.E, Risi, C.M.
Deposit date:	2020-11-06
Release date:	2021-03-24
Last modified:	2024-03-06
Method:	ELECTRON MICROSCOPY (8 Å)
Cite:	The structure of the native cardiac thin filament at systolic Ca 2+ levels. Proc.Natl.Acad.Sci.USA, 118, 2021

7KO5

Structure of cardiac native thin filament at pCa=5.8 having upper and lower troponins in Ca2+ bound state
Descriptor:	Actin, alpha skeletal muscle, Tropomyosin alpha-1 chain, ...
Authors:	Galkin, V.E, Risi, C.M.
Deposit date:	2020-11-06
Release date:	2021-03-24
Last modified:	2024-03-06
Method:	ELECTRON MICROSCOPY (7.8 Å)
Cite:	The structure of the native cardiac thin filament at systolic Ca 2+ levels. Proc.Natl.Acad.Sci.USA, 118, 2021

7KOR

Structure of cardiac native thin filament at pCa=5.8 having upper troponin in Ca2+ bound state and lower troponin in Ca2+ free state
Descriptor:	Actin, alpha skeletal muscle, Tropomyosin alpha-1 chain, ...
Authors:	Galkin, V.E, Risi, C.M.
Deposit date:	2020-11-09
Release date:	2021-03-24
Last modified:	2024-03-06
Method:	ELECTRON MICROSCOPY (7.8 Å)
Cite:	The structure of the native cardiac thin filament at systolic Ca 2+ levels. Proc.Natl.Acad.Sci.USA, 118, 2021

7KO7

Structure of the native cardiac thin filament at pCa=5.8 having upper Tn in Ca2+ free state and lower Tn in Ca2+ bound state
Descriptor:	Actin, alpha skeletal muscle, Tropomyosin alpha-1 chain, ...
Authors:	Galkin, V.E, Risi, C.M.
Deposit date:	2020-11-06
Release date:	2021-03-24
Last modified:	2024-03-06
Method:	ELECTRON MICROSCOPY (8.3 Å)
Cite:	The structure of the native cardiac thin filament at systolic Ca 2+ levels. Proc.Natl.Acad.Sci.USA, 118, 2021

7KON

Structure of upper Tn Ca2+ free (rotated) and lower Tn Ca2+ bound cardiac native thin filament at pCa=5.8
Descriptor:	Actin, alpha skeletal muscle, Tropomyosin alpha-1 chain, ...
Authors:	Galkin, V.E, Risi, C.M.
Deposit date:	2020-11-09
Release date:	2021-03-24
Last modified:	2024-05-29
Method:	ELECTRON MICROSCOPY (8.1 Å)
Cite:	The structure of the native cardiac thin filament at systolic Ca 2+ levels. Proc.Natl.Acad.Sci.USA, 118, 2021

8UZX

The structure of the native cardiac thin filament troponin core in Ca2+-bound fully activated state from the upper strand
Descriptor:	ADENOSINE-5'-DIPHOSPHATE, Actin, alpha cardiac muscle 1, ...
Authors:	Galkin, V.E, Risi, C.M.
Deposit date:	2023-11-16
Release date:	2024-03-06
Last modified:	2024-03-13
Method:	ELECTRON MICROSCOPY (5.4 Å)
Cite:	Troponin Structural Dynamics in the Native Cardiac Thin Filament Revealed by Cryo Electron Microscopy. J.Mol.Biol., 436, 2024

8UWY

The structure of the native cardiac thin filament troponin core in Ca2+-free rotated state from the upper strand
Descriptor:	Actin, alpha cardiac muscle 1, Tropomyosin alpha-1 chain, ...
Authors:	Galkin, V.E, Risi, C.M.
Deposit date:	2023-11-08
Release date:	2024-03-06
Last modified:	2024-03-13
Method:	ELECTRON MICROSCOPY (5.5 Å)
Cite:	Troponin Structural Dynamics in the Native Cardiac Thin Filament Revealed by Cryo Electron Microscopy. J.Mol.Biol., 436, 2024

8UZY

The structure of the native cardiac thin filament troponin core in Ca2+-bound partially activated state from the upper strand
Descriptor:	ADENOSINE-5'-DIPHOSPHATE, Actin, alpha cardiac muscle 1, ...
Authors:	Galkin, V.E, Risi, C.M.
Deposit date:	2023-11-16
Release date:	2024-03-06
Last modified:	2024-03-13
Method:	ELECTRON MICROSCOPY (5.3 Å)
Cite:	Troponin Structural Dynamics in the Native Cardiac Thin Filament Revealed by Cryo Electron Microscopy. J.Mol.Biol., 436, 2024

8UWW

The structure of the native cardiac thin filament troponin core in Ca2+-free state from the upper strand
Descriptor:	Actin, alpha cardiac muscle 1, Tropomyosin alpha-1 chain, ...
Authors:	Galkin, V.E, Risi, C.M.
Deposit date:	2023-11-08
Release date:	2024-03-06
Last modified:	2024-03-13
Method:	ELECTRON MICROSCOPY (5.1 Å)
Cite:	Troponin Structural Dynamics in the Native Cardiac Thin Filament Revealed by Cryo Electron Microscopy. J.Mol.Biol., 436, 2024

8V01

The structure of the native cardiac thin filament troponin core in Ca2+-bound fully activated state 1 from the lower strand
Descriptor:	ADENOSINE-5'-DIPHOSPHATE, Actin, alpha cardiac muscle 1, ...
Authors:	Galkin, V.E, Risi, C.M.
Deposit date:	2023-11-16
Release date:	2024-03-06
Last modified:	2024-03-13
Method:	ELECTRON MICROSCOPY (5.5 Å)
Cite:	Troponin Structural Dynamics in the Native Cardiac Thin Filament Revealed by Cryo Electron Microscopy. J.Mol.Biol., 436, 2024

8UZ6

The structure of the native cardiac thin filament troponin core in Ca2+-free tilted state from the lower strand
Descriptor:	ADENOSINE-5'-DIPHOSPHATE, Actin, alpha cardiac muscle 1, ...
Authors:	Galkin, V.E, Risi, C.M.
Deposit date:	2023-11-14
Release date:	2024-03-06
Last modified:	2024-03-13
Method:	ELECTRON MICROSCOPY (7.1 Å)
Cite:	Troponin Structural Dynamics in the Native Cardiac Thin Filament Revealed by Cryo Electron Microscopy. J.Mol.Biol., 436, 2024

8UZ5

The structure of the native cardiac thin filament troponin core in Ca2+-free rotated state from the lower strand
Descriptor:	ADENOSINE-5'-DIPHOSPHATE, Actin, alpha cardiac muscle 1, ...
Authors:	Galkin, V.E, Risi, C.M.
Deposit date:	2023-11-14
Release date:	2024-03-06
Last modified:	2024-03-13
Method:	ELECTRON MICROSCOPY (5.9 Å)
Cite:	Troponin Structural Dynamics in the Native Cardiac Thin Filament Revealed by Cryo Electron Microscopy. J.Mol.Biol., 436, 2024

8V0Y

The structure of the native cardiac thin filament troponin core in Ca2+-free state from the upper strand activated by the C1-domain of cardiac myosin binding protein C
Descriptor:	ADENOSINE-5'-DIPHOSPHATE, Actin, alpha cardiac muscle 1, ...
Authors:	Galkin, V.E, Risi, C.M.
Deposit date:	2023-11-17
Release date:	2024-03-06
Last modified:	2024-03-13
Method:	ELECTRON MICROSCOPY (7 Å)
Cite:	Troponin Structural Dynamics in the Native Cardiac Thin Filament Revealed by Cryo Electron Microscopy. J.Mol.Biol., 436, 2024

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Displayed results:	25
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