3D6R
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8R1J
| Structure of avian H5N1 influenza A polymerase dimer in complex with human ANP32B. | Descriptor: | Acidic leucine-rich nuclear phosphoprotein 32 family member B, Polymerase acidic protein, Polymerase basic protein 2, ... | Authors: | Carrique, L, Staller, E, Keown, J.R, Fan, H, Fodor, E, Grimes, J.M. | Deposit date: | 2023-11-02 | Release date: | 2024-05-08 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structures of H5N1 influenza polymerase with ANP32B reveal mechanisms of genome replication and host adaptation. Nat Commun, 15, 2024
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8R1L
| Structure of avian H5N1 influenza A polymerase in complex with human ANP32B. | Descriptor: | Acidic leucine-rich nuclear phosphoprotein 32 family member B, Polymerase acidic protein, Polymerase basic protein 2, ... | Authors: | Carrique, L, Staller, E, Keown, J.R, Fan, H, Fodor, E, Grimes, J.M. | Deposit date: | 2023-11-02 | Release date: | 2024-05-08 | Last modified: | 2024-07-31 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structures of H5N1 influenza polymerase with ANP32B reveal mechanisms of genome replication and host adaptation. Nat Commun, 15, 2024
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8PJE
| Human Leukocyte Antigen class II allotype DR1 presenting influenza A virus haemagglutinin (HA)306-318 PKYVKQNTLKLAT | Descriptor: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, ... | Authors: | MacLachlan, B.J, Wall, A, Greenshields-Watson, A.L, Hesketh, S.J, Cole, D.K, Rizkallah, P.J, Godkin, A.J. | Deposit date: | 2023-06-23 | Release date: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | A targeted single mutation in influenza A virus universal epitope transforms immunogenicity and protective immunity via CD4 + T cell activation. Cell Rep, 43, 2024
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8PJF
| Human Leukocyte Antigen class II allotype DR1 presenting P11T->R modified influenza A virus haemagglutinin (HA)306-318 PKYVKQNTLKLAR | Descriptor: | 1,2-ETHANEDIOL, HLA class II histocompatibility antigen, DR alpha chain, ... | Authors: | MacLachlan, B.J, Wall, A, Greenshields-Watson, A.L, Cole, D.K, Rizkallah, P.J, Godkin, A.J. | Deposit date: | 2023-06-23 | Release date: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.48 Å) | Cite: | A targeted single mutation in influenza A virus universal epitope transforms immunogenicity and protective immunity via CD4 + T cell activation. Cell Rep, 43, 2024
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8PJG
| F11 TCR in complex with Human Leukocyte Antigen class II allotype DR1 presenting P11T->R modified influenza A virus haemagglutinin (HA)306-318 PKYVKQNTLKLAR | Descriptor: | 1,2-ETHANEDIOL, 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, HLA class II histocompatibility antigen, ... | Authors: | MacLachlan, B.J, Wall, A, Greenshields-Watson, A.L, Cole, D.K, Rizkallah, P.J, Godkin, A.J. | Deposit date: | 2023-06-23 | Release date: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | A targeted single mutation in influenza A virus universal epitope transforms immunogenicity and protective immunity via CD4 + T cell activation. Cell Rep, 43, 2024
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6XZG
| Influenza C virus polymerase in complex with chicken ANP32A - Subclass 3 | Descriptor: | Influenza viral RNA (vRNA) promoter 47mer, LRRcap domain-containing protein, Polymerase acidic protein, ... | Authors: | Carrique, L, Keown, J.R, Fan, H, Grimes, J.M, Fodor, E. | Deposit date: | 2020-02-04 | Release date: | 2020-11-25 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Host ANP32A mediates the assembly of the influenza virus replicase. Nature, 587, 2020
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6XZR
| Influenza C virus polymerase in complex with chicken ANP32A - Subclass 1 | Descriptor: | LRRcap domain-containing protein, Polymerase acidic protein, Polymerase basic protein 2, ... | Authors: | Carrique, L, Keown, J.R, Fan, H, Grimes, J.M, Fodor, E. | Deposit date: | 2020-02-05 | Release date: | 2020-11-25 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Host ANP32A mediates the assembly of the influenza virus replicase. Nature, 587, 2020
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6XZP
| Influenza C virus polymerase in complex with chicken ANP32A - Subclass 4 | Descriptor: | LRRcap domain-containing protein, Polymerase acidic protein, Polymerase basic protein 2, ... | Authors: | Carrique, L, Keown, J.R, Fan, H, Grimes, J.M, Fodor, E. | Deposit date: | 2020-02-05 | Release date: | 2020-11-25 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Host ANP32A mediates the assembly of the influenza virus replicase. Nature, 587, 2020
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6Y0C
| Influenza C virus polymerase in complex with human ANP32A - Subclass 2 | Descriptor: | Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-R(*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*GP*CP*CP*UP*UP*UP*U)-3'), ... | Authors: | Fan, H, Carrique, L, Keown, J.R, Grimes, J.M, Fodor, E. | Deposit date: | 2020-02-07 | Release date: | 2020-11-25 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Host ANP32A mediates the assembly of the influenza virus replicase. Nature, 587, 2020
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6XZD
| Influenza C virus polymerase complex without chicken ANP32A - Subclass 2 | Descriptor: | Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-R(*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*GP*CP*CP*CP*UP*GP*C)-3'), ... | Authors: | Keown, J.R, Carrique, L, Fan, H, Grimes, J.M, Fodor, E. | Deposit date: | 2020-02-04 | Release date: | 2020-12-23 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Host ANP32A mediates the assembly of the influenza virus replicase. Nature, 587, 2020
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6XZQ
| Influenza C virus polymerase in complex with human ANP32A - Subclass 1 | Descriptor: | Acidic leucine-rich nuclear phosphoprotein 32 family member A, Polymerase acidic protein, Polymerase basic protein 2, ... | Authors: | Fan, H, Carrique, L, Keown, J.R, Grimes, J.M, Fodor, E. | Deposit date: | 2020-02-05 | Release date: | 2020-11-25 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Host ANP32A mediates the assembly of the influenza virus replicase. Nature, 587, 2020
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