7Y3A
 
 | | Crystal structure of TRIM7 bound to 2C | | Descriptor: | E3 ubiquitin-protein ligase TRIM7,E3 ubiquitin-protein ligase TRIM7,E3 ubiquitin-protein ligase TRIM7,TRIM7-2C | | Authors: | Dong, C, Yan, X. | | Deposit date: | 2022-06-10 | | Release date: | 2022-08-03 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | C-terminal glutamine acts as a C-degron targeted by E3 ubiquitin ligase TRIM7.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7Y3B
 | | Crystal structure of TRIM7 bound to GN1 | | Descriptor: | E3 ubiquitin-protein ligase TRIM7,TRIM7-GN1 | | Authors: | Dong, C, Yan, X. | | Deposit date: | 2022-06-10 | | Release date: | 2022-08-03 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.76 Å) | | Cite: | C-terminal glutamine acts as a C-degron targeted by E3 ubiquitin ligase TRIM7.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7Y3C
 | | Crystal structure of TRIM7 bound to RACO-1 | | Descriptor: | E3 ubiquitin-protein ligase TRIM7,E3 ubiquitin-protein ligase TRIM7,TRIM7-RACO-1 | | Authors: | Dong, C, Yan, X. | | Deposit date: | 2022-06-10 | | Release date: | 2022-08-03 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.71 Å) | | Cite: | C-terminal glutamine acts as a C-degron targeted by E3 ubiquitin ligase TRIM7.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7WUI
 | | Tethered peptide activation mechanism of adhesion GPCRs ADGRG2 and ADGRG4 | | Descriptor: | Adhesion G-protein coupled receptor G2,mCherry, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Guo, S.C, He, Q.T, Xiao, P, Sun, J.P, Yu, X. | | Deposit date: | 2022-02-08 | | Release date: | 2022-04-27 | | Last modified: | 2022-05-11 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Tethered peptide activation mechanism of the adhesion GPCRs ADGRG2 and ADGRG4.
Nature, 604, 2022
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7WUQ
 | | Tethered peptide activation mechanism of adhesion GPCRs ADGRG2 and ADGRG4 | | Descriptor: | Adhesion G-protein coupled receptor G2,mCherry, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | He, Q.T, Guo, S.C, Xiao, P, Sun, J.P, Yu, X, Gou, L, Kong, L.L, Zhang, L. | | Deposit date: | 2022-02-09 | | Release date: | 2022-04-27 | | Last modified: | 2022-05-11 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Tethered peptide activation mechanism of the adhesion GPCRs ADGRG2 and ADGRG4.
Nature, 604, 2022
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7WUJ
 | | Tethered peptide activation mechanism of adhesion GPCRs ADGRG2 and ADGRG4 | | Descriptor: | Adhesion G-protein coupled receptor G4,Uncharacterized protein, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Guo, S.C, Huang, S.M, He, Q.T, Xiao, P, Sun, J.P, Yu, X. | | Deposit date: | 2022-02-08 | | Release date: | 2022-04-27 | | Last modified: | 2022-05-11 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Tethered peptide activation mechanism of the adhesion GPCRs ADGRG2 and ADGRG4.
Nature, 604, 2022
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5ZNZ
 | | Structure of mDR3 DD with MBP tag mutant-I387V | | Descriptor: | Maltose-binding periplasmic protein,Tumor necrosis factor receptor superfamily, member 25, SULFATE ION | | Authors: | Jin, T, Yin, X. | | Deposit date: | 2018-04-12 | | Release date: | 2019-04-17 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Crystal structure and activation mechanism of DR3 death domain.
Febs J., 286, 2019
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5ZNY
 | | Structure of mDR3_DD-C363G with MBP tag | | Descriptor: | Maltose-binding periplasmic protein,Tumor necrosis factor receptor superfamily, member 25, SULFATE ION | | Authors: | Yin, X, Jin, T. | | Deposit date: | 2018-04-11 | | Release date: | 2019-04-17 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.74 Å) | | Cite: | Crystal structure and activation mechanism of DR3 death domain.
Febs J., 286, 2019
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5YF4
 | | A kinase complex MST4-MOB4 | | Descriptor: | MOB-like protein phocein, Peptide from Serine/threonine-protein kinase 26, ZINC ION | | Authors: | Chen, M, Zhou, Z.C. | | Deposit date: | 2017-09-20 | | Release date: | 2018-08-15 | | Last modified: | 2018-09-26 | | Method: | X-RAY DIFFRACTION (1.897 Å) | | Cite: | The MST4-MOB4 complex disrupts the MST1-MOB1 complex in the Hippo-YAP pathway and plays a pro-oncogenic role in pancreatic cancer.
J. Biol. Chem., 293, 2018
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8JHZ
 | | Cryo-EM structure of the TcsH-TMPRSS2 complex | | Descriptor: | Hemorrhagic toxin, Transmembrane protease serine 2, ZINC ION | | Authors: | Zhou, R, Liang, T, Zhan, X. | | Deposit date: | 2023-05-25 | | Release date: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Molecular basis of TMPRSS2 recognition by Paeniclostridium sordellii hemorrhagic toxin.
Nat Commun, 15, 2024
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8JI0
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6JQ2
 | | Crystal Structure of H2-Kb in complex with a DPAGT1 self-peptide | | Descriptor: | Beta-2-microglobulin, DPATG1 antigen SIIVFNLV, H-2 class I histocompatibility antigen, ... | | Authors: | Bai, P, Yin, L. | | Deposit date: | 2019-03-28 | | Release date: | 2020-04-01 | | Last modified: | 2021-02-17 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Immune-based mutation classification enables neoantigen prioritization and immune feature discovery in cancer immunotherapy.
Oncoimmunology, 10, 2021
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6JQ3
 | | Crystal Structure of H2-Kb in complex with a DPAGT1 mutant peptide | | Descriptor: | Beta-2-microglobulin, DPAGT1 mutant antigen SIIVFNLL, H-2 class I histocompatibility antigen, ... | | Authors: | Bai, P, Zhou, Q, Wei, P, Yin, L. | | Deposit date: | 2019-03-28 | | Release date: | 2020-05-06 | | Last modified: | 2021-02-17 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Immune-based mutation classification enables neoantigen prioritization and immune feature discovery in cancer immunotherapy.
Oncoimmunology, 10, 2021
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6JTN
 | | Crystal structure of HLA-C08 in complex with a tumor mut10m peptide | | Descriptor: | 10-mer peptide, Beta-2-microglobulin, HLA class I antigen, ... | | Authors: | Bai, P, Zhou, Q, Wei, P, Yin, L. | | Deposit date: | 2019-04-11 | | Release date: | 2020-04-15 | | Last modified: | 2021-02-17 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Immune-based mutation classification enables neoantigen prioritization and immune feature discovery in cancer immunotherapy.
Oncoimmunology, 10, 2021
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6KIJ
 | | Crystal structure of yedK with ssDNA containing an abasic site | | Descriptor: | DNA (5'-D(*GP*AP*TP*TP*CP*GP*TP*CP*G)-3'), GLYCEROL, PENTANE-3,4-DIOL-5-PHOSPHATE, ... | | Authors: | Wang, N, Bao, H, Huang, H. | | Deposit date: | 2019-07-18 | | Release date: | 2019-08-07 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.58 Å) | | Cite: | Molecular basis of abasic site sensing in single-stranded DNA by the SRAP domain of E. coli yedK.
Nucleic Acids Res., 47, 2019
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6KIZ
 | | Cryo-EM structure of human MLL1-NCP complex, binding mode2 | | Descriptor: | DNA (145-MER), Histone H2A, Histone H2B 1.1, ... | | Authors: | Huang, J, Xue, H, Yao, T. | | Deposit date: | 2019-07-20 | | Release date: | 2019-09-11 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (4.5 Å) | | Cite: | Structural basis of nucleosome recognition and modification by MLL methyltransferases.
Nature, 573, 2019
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5Z0Q
 | | Crystal Structure of OvoB | | Descriptor: | Aminotransferase, class I and II, PYRIDOXAL-5'-PHOSPHATE | | Authors: | Cai, Y.J, Huang, P, Wu, L, Zhou, J.H, Liu, P.H. | | Deposit date: | 2017-12-20 | | Release date: | 2018-11-07 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.77 Å) | | Cite: | In Vitro Reconstitution of the Remaining Steps in Ovothiol A Biosynthesis: C-S Lyase and Methyltransferase Reactions.
Org. Lett., 20, 2018
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6KBZ
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6KIW
 | | Cryo-EM structure of human MLL3-ubNCP complex (4.0 angstrom) | | Descriptor: | DNA (144-MER), DNA (145-MER), Histone H2A, ... | | Authors: | Huang, J, Xue, H, Yao, T. | | Deposit date: | 2019-07-20 | | Release date: | 2019-09-11 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Structural basis of nucleosome recognition and modification by MLL methyltransferases.
Nature, 573, 2019
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6KBU
 | | Crystal structure of yedK | | Descriptor: | GLYCEROL, SOS response-associated protein | | Authors: | Wang, N, Bao, H, Huang, H. | | Deposit date: | 2019-06-26 | | Release date: | 2019-07-10 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Molecular basis of abasic site sensing in single-stranded DNA by the SRAP domain of E. coli yedK.
Nucleic Acids Res., 47, 2019
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6KBX
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6KL4
 | | Crystal structure of MavC-UBE2N-Ub | | Descriptor: | MavC, Ub, Ubiquitin-conjugating enzyme E2 N | | Authors: | Ouyang, S, Guan, H. | | Deposit date: | 2019-07-29 | | Release date: | 2020-04-15 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | Molecular Basis of Ubiquitination Catalyzed by the Bacterial Transglutaminase MavC.
Adv Sci, 7, 2020
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6KBS
 | | Crystal structure of yedK in complex with ssDNA | | Descriptor: | DNA (5'-D(*CP*GP*GP*TP*CP*GP*AP*TP*TP*C)-3'), SOS response-associated protein | | Authors: | Wang, N, Bao, H, Huang, H. | | Deposit date: | 2019-06-26 | | Release date: | 2019-07-10 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.601 Å) | | Cite: | Molecular basis of abasic site sensing in single-stranded DNA by the SRAP domain of E. coli yedK.
Nucleic Acids Res., 47, 2019
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6KCQ
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6KIX
 | | Cryo-EM structure of human MLL1-NCP complex, binding mode1 | | Descriptor: | DNA (145-MER), GLUTAMINE, Histone H2A, ... | | Authors: | Huang, J, Xue, H, Yao, T. | | Deposit date: | 2019-07-20 | | Release date: | 2019-09-11 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Structural basis of nucleosome recognition and modification by MLL methyltransferases.
Nature, 573, 2019
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