3K8W
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3K3T
| E185A mutant of peptidoglycan hydrolase from Sphingomonas sp. A1 | Descriptor: | Peptidoglycan hydrolase FlgJ, SULFATE ION | Authors: | Maruyama, Y, Ochiai, A, Itoh, T, Mikami, B, Hashimoto, W, Murata, K. | Deposit date: | 2009-10-04 | Release date: | 2010-07-14 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Mutational studies of the peptidoglycan hydrolase FlgJ of Sphingomonas sp. strain A1 J.Basic Microbiol., 50, 2010
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3K8V
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2GH4
| YteR/D143N/dGalA-Rha | Descriptor: | 2,6-anhydro-3-deoxy-L-threo-hex-2-enonic acid-(1-2)-alpha-L-rhamnopyranose, Putative glycosyl hydrolase yteR | Authors: | Itoh, T, Ochiai, A, Mikami, B, Hashimoto, W, Murata, K. | Deposit date: | 2006-03-25 | Release date: | 2006-08-29 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of unsaturated rhamnogalacturonyl hydrolase complexed with substrate Biochem.Biophys.Res.Commun., 347, 2006
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5GX7
| Crystal structure of solute-binding protein complexed with unsaturated chondroitin disaccharide with a sulfate group at C-6 position of GalNAc | Descriptor: | 4-deoxy-alpha-L-threo-hex-4-enopyranuronic acid-(1-3)-2-acetamido-2-deoxy-6-O-sulfo-beta-D-galactopyranose, CALCIUM ION, Extracellular solute-binding protein family 1 | Authors: | Oiki, S, Mikami, B, Murata, K, Hashimoto, W. | Deposit date: | 2016-09-15 | Release date: | 2017-07-19 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.991 Å) | Cite: | A bacterial ABC transporter enables import of mammalian host glycosaminoglycans Sci Rep, 7, 2017
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5GUB
| Crystal structure of solute-binding protein complexed with sulfate group-free unsaturated chondroitin disaccharide | Descriptor: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-deoxy-alpha-L-threo-hex-4-enopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose, ... | Authors: | Oiki, S, Mikami, B, Murata, K, Hashimoto, W. | Deposit date: | 2016-08-26 | Release date: | 2017-07-19 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | A bacterial ABC transporter enables import of mammalian host glycosaminoglycans Sci Rep, 7, 2017
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7CJ3
| Crystal structure of the transmembrane domain of Salpingoeca rosetta rhodopsin phosphodiesterase | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Phosphodiesterase, RETINAL | Authors: | Ikuta, T, Shihoya, W, Yamashita, K, Nureki, O. | Deposit date: | 2020-07-09 | Release date: | 2020-11-25 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural insights into the mechanism of rhodopsin phosphodiesterase. Nat Commun, 11, 2020
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5GX8
| Crystal structure of solute-binding protein related to glycosaminoglycans | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, D(-)-TARTARIC ACID, ... | Authors: | Oiki, S, Mikami, B, Murata, K, Hashimoto, W. | Deposit date: | 2016-09-15 | Release date: | 2017-07-19 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.778 Å) | Cite: | A bacterial ABC transporter enables import of mammalian host glycosaminoglycans Sci Rep, 7, 2017
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5GX6
| Crystal structure of solute-binding protein complexed with unsaturated chondroitin disaccharide with a sulfate group at C-4 position of GalNAc | Descriptor: | 1,2-ETHANEDIOL, 4-deoxy-alpha-L-threo-hex-4-enopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose, CALCIUM ION, ... | Authors: | Oiki, S, Mikami, B, Murata, K, Hashimoto, W. | Deposit date: | 2016-09-15 | Release date: | 2017-07-26 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | A bacterial ABC transporter enables import of mammalian host glycosaminoglycans Sci Rep, 7, 2017
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2FUZ
| UGL hexagonal crystal structure without glycine and DTT molecules | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Unsaturated glucuronyl hydrolase | Authors: | Itoh, T, Hashimoto, W, Mikami, B, Murata, K. | Deposit date: | 2006-01-28 | Release date: | 2006-05-30 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Substrate recognition by unsaturated glucuronyl hydrolase from Bacillus sp. GL1 Biochem.Biophys.Res.Commun., 344, 2006
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7D7P
| Crystal structure of the phosphodiesterase domain of Salpingoeca rosetta rhodopsin phosphodiesterase | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ... | Authors: | Ikuta, T, Shihoya, W, Yamashita, K, Nureki, O. | Deposit date: | 2020-10-05 | Release date: | 2020-11-18 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural insights into the mechanism of rhodopsin phosphodiesterase. Nat Commun, 11, 2020
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2FV0
| UGL_D88N/dGlcA-Glc-Rha-Glc | Descriptor: | 2,6-anhydro-3-deoxy-L-threo-hex-2-enonic acid-(1-4)-beta-D-glucopyranose-(1-4)-alpha-L-rhamnopyranose-(1-3)-beta-D-glucopyranose, Unsaturated glucuronyl hydrolase | Authors: | Itoh, T, Hashimoto, W, Mikami, B, Murata, K. | Deposit date: | 2006-01-28 | Release date: | 2006-05-30 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | Substrate recognition by unsaturated glucuronyl hydrolase from Bacillus sp. GL1 Biochem.Biophys.Res.Commun., 344, 2006
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2FV1
| UGL_D88N/dGlcA-GlcNAc | Descriptor: | 2,6-anhydro-3-deoxy-L-threo-hex-2-enonic acid-(1-3)-2-acetamido-2-deoxy-alpha-D-glucopyranose, Unsaturated glucuronyl hydrolase | Authors: | Itoh, T, Hashimoto, W, Mikami, B, Murata, K. | Deposit date: | 2006-01-28 | Release date: | 2006-05-30 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | Substrate recognition by unsaturated glucuronyl hydrolase from Bacillus sp. GL1 Biochem.Biophys.Res.Commun., 344, 2006
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6LMU
| Cryo-EM structure of the human CALHM2 | Descriptor: | Calcium homeostasis modulator protein 2 | Authors: | Demura, K, Kusakizako, T, Shihoya, W, Hiraizumi, M, Shimada, H, Yamashita, K, Nishizawa, T, Nureki, O. | Deposit date: | 2019-12-26 | Release date: | 2020-07-29 | Last modified: | 2020-09-09 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-EM structures of calcium homeostasis modulator channels in diverse oligomeric assemblies. Sci Adv, 6, 2020
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7D7Q
| Crystal structure of the transmembrane domain and linker region of Salpingoeca rosetta rhodopsin phosphodiesterase | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Phosphodiesterase, RETINAL | Authors: | Ikuta, T, Shihoya, W, Yamashita, K, Nureki, O. | Deposit date: | 2020-10-05 | Release date: | 2020-11-18 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structural insights into the mechanism of rhodopsin phosphodiesterase. Nat Commun, 11, 2020
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6LMX
| Cryo-EM structure of the CALHM chimeric construct (9-mer) | Descriptor: | Calcium homeostasis modulator 1,Calcium homeostasis modulator protein 2 | Authors: | Demura, K, Kusakizako, T, Shihoya, W, Hiraizumi, M, Shimada, H, Yamashita, K, Nishizawa, T, Nureki, O. | Deposit date: | 2019-12-26 | Release date: | 2020-07-29 | Last modified: | 2020-09-09 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-EM structures of calcium homeostasis modulator channels in diverse oligomeric assemblies. Sci Adv, 6, 2020
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6LMV
| Cryo-EM structure of the C. elegans CLHM-1 | Descriptor: | Calcium homeostasis modulator protein | Authors: | Demura, K, Kusakizako, T, Shihoya, W, Hiraizumi, M, Shimada, H, Yamashita, K, Nishizawa, T, Nureki, O. | Deposit date: | 2019-12-26 | Release date: | 2020-07-29 | Last modified: | 2020-09-09 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Cryo-EM structures of calcium homeostasis modulator channels in diverse oligomeric assemblies. Sci Adv, 6, 2020
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6LMW
| Cryo-EM structure of the CALHM chimeric construct (8-mer) | Descriptor: | Calcium homeostasis modulator 1,Calcium homeostasis modulator protein 2 | Authors: | Demura, K, Kusakizako, T, Shihoya, W, Hiraizumi, M, Shimada, H, Yamashita, K, Nishizawa, T, Nureki, O. | Deposit date: | 2019-12-26 | Release date: | 2020-07-29 | Last modified: | 2020-09-09 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-EM structures of calcium homeostasis modulator channels in diverse oligomeric assemblies. Sci Adv, 6, 2020
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6LMT
| Cryo-EM structure of the killifish CALHM1 | Descriptor: | CHOLESTEROL HEMISUCCINATE, Calcium homeostasis modulator 1 | Authors: | Demura, K, Kusakizako, T, Shihoya, W, Hiraizumi, M, Shimada, H, Yamashita, K, Nishizawa, T, Nureki, O. | Deposit date: | 2019-12-26 | Release date: | 2020-07-29 | Last modified: | 2020-09-09 | Method: | ELECTRON MICROSCOPY (2.66 Å) | Cite: | Cryo-EM structures of calcium homeostasis modulator channels in diverse oligomeric assemblies. Sci Adv, 6, 2020
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5WUV
| Crystal structure of Certolizumab Fab | Descriptor: | heavy chain, light chain | Authors: | Heo, Y.S, Lee, J.U, Son, J.Y, Shin, W, Yoo, K.Y. | Deposit date: | 2016-12-21 | Release date: | 2017-06-07 | Method: | X-RAY DIFFRACTION (1.952 Å) | Cite: | Molecular Basis for the Neutralization of Tumor Necrosis Factor alpha by Certolizumab Pegol in the Treatment of Inflammatory Autoimmune Diseases Int J Mol Sci, 18, 2017
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6LPB
| Cryo-EM structure of the human PAC1 receptor coupled to an engineered heterotrimeric G protein | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | Authors: | Kobayashi, K, Shihoya, W, Nishizawa, T, Nureki, O. | Deposit date: | 2020-01-09 | Release date: | 2020-03-11 | Last modified: | 2020-03-25 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Cryo-EM structure of the human PAC1 receptor coupled to an engineered heterotrimeric G protein. Nat.Struct.Mol.Biol., 27, 2020
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4F13
| Alginate lyase A1-III Y246F complexed with tetrasaccharide | Descriptor: | 4-deoxy-alpha-L-erythro-hex-4-enopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid, Alginate lyase, beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid | Authors: | Mikami, B, Ban, M, Suzuki, S, Yoon, H.-J, Miyake, O, Yamasaki, M, Ogura, K, Maruyama, Y, Hashimoto, W, Murata, K. | Deposit date: | 2012-05-06 | Release date: | 2012-06-27 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.208 Å) | Cite: | Induced-fit motion of a lid loop involved in catalysis in alginate lyase A1-III Acta Crystallogr.,Sect.D, 68, 2012
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4F10
| Alginate lyase A1-III H192A complexed with tetrasaccharide | Descriptor: | 4-deoxy-alpha-L-erythro-hex-4-enopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid, Alginate lyase, alpha-L-gulopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid | Authors: | Mikami, B, Ban, M, Suzuki, S, Yoon, H.-J, Miyake, O, Yamasaki, M, Ogura, K, Maruyama, Y, Hashimoto, W, Murata, K. | Deposit date: | 2012-05-05 | Release date: | 2012-06-27 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Induced-fit motion of a lid loop involved in catalysis in alginate lyase A1-III Acta Crystallogr.,Sect.D, 68, 2012
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4E1Y
| Alginate lyase A1-III H192A apo form | Descriptor: | Alginate lyase | Authors: | Mikami, B, Ban, M, Suzuki, S, Yoon, H.-J, Miyake, O, Yamasaki, M, Ogura, K, Maruyama, Y, Hashimoto, W, Murata, K. | Deposit date: | 2012-03-07 | Release date: | 2012-04-11 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Induced-fit motion of a lid loop involved in catalysis in alginate lyase A1-III Acta Crystallogr.,Sect.D, 68, 2012
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1IBQ
| ASPERGILLOPEPSIN FROM ASPERGILLUS PHOENICIS | Descriptor: | ASPERGILLOPEPSIN, ZINC ION, alpha-D-mannopyranose | Authors: | Cho, S.W, Shin, W. | Deposit date: | 2001-03-28 | Release date: | 2001-07-04 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | Structure of aspergillopepsin I from Aspergillus phoenicis: variations of the S1'-S2 subsite in aspartic proteinases. Acta Crystallogr.,Sect.D, 57, 2001
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