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2QJC
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BU of 2qjc by Molmil
Crystal structure of a putative diadenosine tetraphosphatase
Descriptor: Diadenosine tetraphosphatase, putative, MANGANESE (II) ION, ...
Authors:Sugadev, R, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2007-07-06
Release date:2007-07-24
Last modified:2021-02-03
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural genomics of protein phosphatases.
J.Struct.Funct.Genom., 8, 2007
8FM6
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BU of 8fm6 by Molmil
Dri1 hemoprotein variant H21A with a zinc-mirror heme site
Descriptor: HEME B/C, Ssr1698 protein
Authors:Yee, E.F, Blaby-Haas, C.
Deposit date:2022-12-22
Release date:2024-04-24
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:A hemoprotein with a zinc-mirror heme site ties heme availability to carbon metabolism in cyanobacteria.
Nat Commun, 15, 2024
8GAB
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BU of 8gab by Molmil
Crystal structure of CTLA-4 in complex with a high affinity CTLA-4 binder
Descriptor: CTLA-4 binder, Cytotoxic T-lymphocyte protein 4, POTASSIUM ION
Authors:Yang, W, Almo, S.C, Ghosh, A.
Deposit date:2023-02-22
Release date:2024-08-21
Last modified:2024-08-28
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:Design of High Affinity Binders to Convex Protein Target Sites.
Biorxiv, 2024
8GAC
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BU of 8gac by Molmil
Crystal structure of a high affinity CTLA-4 binder
Descriptor: 1,2-ETHANEDIOL, CTLA-4 binder
Authors:Yang, W, Almo, S.C, Ghosh, A.
Deposit date:2023-02-22
Release date:2024-08-21
Last modified:2024-08-28
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Design of High Affinity Binders to Convex Protein Target Sites.
Biorxiv, 2024
8GAD
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BU of 8gad by Molmil
Crystal structure of a high affinity PD-L1 binder
Descriptor: INDOLE, PD-L1 binder
Authors:Yang, W, Almo, S.C, Ghosh, A.
Deposit date:2023-02-22
Release date:2024-08-21
Last modified:2024-08-28
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Design of High Affinity Binders to Convex Protein Target Sites.
Biorxiv, 2024
2A0W
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BU of 2a0w by Molmil
Structure of human purine nucleoside phosphorylase H257G mutant
Descriptor: 7-[[(3R,4R)-3-(hydroxymethyl)-4-oxidanyl-pyrrolidin-1-ium-1-yl]methyl]-3,5-dihydropyrrolo[3,2-d]pyrimidin-4-one, Purine nucleoside phosphorylase, SULFATE ION
Authors:Murkin, A.S, Shi, W, Schramm, V.L.
Deposit date:2005-06-17
Release date:2006-06-06
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Neighboring group participation in the transition state of human purine nucleoside phosphorylase.
Biochemistry, 46, 2007
2A0X
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BU of 2a0x by Molmil
Structure of human purine nucleoside phosphorylase H257F mutant
Descriptor: 7-[[(3R,4R)-3-(hydroxymethyl)-4-oxidanyl-pyrrolidin-1-ium-1-yl]methyl]-3,5-dihydropyrrolo[3,2-d]pyrimidin-4-one, Purine nucleoside phosphorylase, SULFATE ION
Authors:Murkin, A.S, Shi, W, Schramm, V.L.
Deposit date:2005-06-17
Release date:2006-06-06
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Neighboring group participation in the transition state of human purine nucleoside phosphorylase.
Biochemistry, 46, 2007
1Q8F
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BU of 1q8f by Molmil
Crystal Structure of the E.coli pyrimidine nucleoside hydrolase yeiK
Descriptor: CALCIUM ION, GLYCEROL, Pyrimidine nucleoside hydrolase
Authors:Giabbai, B, Degano, M.
Deposit date:2003-08-21
Release date:2004-05-11
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure to 1.7 a of the Escherichia coli pyrimidine nucleoside hydrolase YeiK, a novel candidate for cancer gene therapy.
STRUCTURE, 12, 2004
3RO6
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BU of 3ro6 by Molmil
Crystal structure of Dipeptide Epimerase from Methylococcus capsulatus complexed with Mg ion
Descriptor: GLYCEROL, MAGNESIUM ION, Putative chloromuconate cycloisomerase, ...
Authors:Lukk, T, Sakai, A, Song, L, Gerlt, J.A, Nair, S.K.
Deposit date:2011-04-25
Release date:2011-05-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Homology models guide discovery of diverse enzyme specificities among dipeptide epimerases in the enolase superfamily.
Proc.Natl.Acad.Sci.USA, 109, 2012
5P21
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BU of 5p21 by Molmil
REFINED CRYSTAL STRUCTURE OF THE TRIPHOSPHATE CONFORMATION OF H-RAS P21 AT 1.35 ANGSTROMS RESOLUTION: IMPLICATIONS FOR THE MECHANISM OF GTP HYDROLYSIS
Descriptor: C-H-RAS P21 PROTEIN, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Pai, E.F, Wittinghofer, A, Kabsch, W.
Deposit date:1990-04-30
Release date:1992-01-15
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Refined crystal structure of the triphosphate conformation of H-ras p21 at 1.35 A resolution: implications for the mechanism of GTP hydrolysis.
EMBO J., 9, 1990
1ASA
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BU of 1asa by Molmil
THE STRUCTURAL BASIS FOR THE REDUCED ACTIVITY OF THE Y226F(Y225F) ACTIVE SITE MUTANT OF E. COLI ASPARTATE AMINOTRANSFERASE
Descriptor: ASPARTATE AMINOTRANSFERASE, MALEIC ACID, PYRIDOXAL-5'-PHOSPHATE
Authors:Schumacher, C, Ringe, D.
Deposit date:1993-08-27
Release date:1994-04-30
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Structural Basis for the Reduced Activity of the Y226F(Y225F) Active Site Mutant of E. Coli Aspartate Aminotransferase
To be Published
8SFV
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BU of 8sfv by Molmil
High affinity nanobodies to GFP
Descriptor: GLYCEROL, Green fluorescent protein, LaG19, ...
Authors:Ketaren, N.E, Rout, M.P, Bonanno, J.B, Almo, S.C.
Deposit date:2023-04-11
Release date:2024-05-22
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:High affinity nanobodies to GFP
To Be Published
8SG3
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BU of 8sg3 by Molmil
High Affinity nanobodies against GFP
Descriptor: Green fluorescent protein, LaG41
Authors:Ketaren, N.E, Rout, M.P, Bonanno, J.B, Almo, S.C.
Deposit date:2023-04-11
Release date:2024-05-22
Method:X-RAY DIFFRACTION (3.11 Å)
Cite:High Affinity nanobodies against GFP
To Be Published
8SFZ
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BU of 8sfz by Molmil
High Affinity nanobodies against GFP
Descriptor: Green fluorescent protein, LaG35, POTASSIUM ION, ...
Authors:Ketaren, N.E, Rout, M.P, Bonanno, J.B, Almo, S.C.
Deposit date:2023-04-11
Release date:2024-05-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:High Affinity nanobodies against GFP
To Be Published
8SFS
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BU of 8sfs by Molmil
High Affinity nanobodies against GFP
Descriptor: AMMONIUM ION, CHLORIDE ION, GLYCEROL, ...
Authors:Ketaren, N.E, Rout, M.P, Bonnano, J.B, Almo, S.C.
Deposit date:2023-04-11
Release date:2024-05-22
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:High Affinity nanobodies against GFP
To Be Published
8GDW
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BU of 8gdw by Molmil
Crystal structure of Domain Related to Iron (DRI) from cyanobacteria
Descriptor: Ssr1698 protein, ZINC ION
Authors:Kumaran, D, Grosjean, N, Blaby, E.C.
Deposit date:2023-03-06
Release date:2024-03-13
Last modified:2024-04-24
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:A hemoprotein with a zinc-mirror heme site ties heme availability to carbon metabolism in cyanobacteria.
Nat Commun, 15, 2024
8GF4
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BU of 8gf4 by Molmil
Crystal structure of Domain Related to Iron (DRI) in complex with heme
Descriptor: PROTOPORPHYRIN IX CONTAINING FE, Ssr1698 protein, ZINC ION
Authors:Kumaran, D, Blaby, E.C.
Deposit date:2023-03-07
Release date:2024-03-13
Last modified:2024-04-24
Method:X-RAY DIFFRACTION (3 Å)
Cite:A hemoprotein with a zinc-mirror heme site ties heme availability to carbon metabolism in cyanobacteria.
Nat Commun, 15, 2024
8GBK
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BU of 8gbk by Molmil
Dri1 hemoprotein variant H79A-R90A with a zinc-mirror heme site
Descriptor: HEME B/C, Ssr1698 protein
Authors:Yee, E.F, Blaby-Haas, C.
Deposit date:2023-02-26
Release date:2024-04-24
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A hemoprotein with a zinc-mirror heme site ties heme availability to carbon metabolism in cyanobacteria.
Nat Commun, 15, 2024
5TC6
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BU of 5tc6 by Molmil
Crystal structure of human 5'-deoxy-5'-methylthioadenosine phosphorylase in complex with propylthio-immucillin-A
Descriptor: (2S,3S,4R,5S)-2-(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-5-[(propylsulfanyl)methyl]pyrrolidine-3,4-diol, CHLORIDE ION, GLYCEROL, ...
Authors:Cameron, S.A, Firestone, R.S, Schramm, V.L, Almo, S.C.
Deposit date:2016-09-14
Release date:2017-10-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:TBA
To be published
5TC7
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BU of 5tc7 by Molmil
Crystal structure of human 5'-deoxy-5'-methylthioadenosine phosphorylase in complex with 5'-methylthiotubercidin at 1.75 angstrom
Descriptor: 2-(4-AMINO-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-METHYLSULFANYLMETHYL-TETRAHYDRO-FURAN-3,4-DIOL, CHLORIDE ION, PHOSPHATE ION, ...
Authors:Cameron, S.A, Firestone, R.S, Schramm, V.L, Almo, S.C.
Deposit date:2016-09-14
Release date:2017-10-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:TBA
To be published
5TC8
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BU of 5tc8 by Molmil
Crystal structure of human 5'-deoxy-5'-methylthioadenosine phosphorylase in complex with methylthio-DADMe-Immucillin-A
Descriptor: (3R,4S)-1-[(4-AMINO-5H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)METHYL]-4-[(METHYLSULFANYL)METHYL]PYRROLIDIN-3-OL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Cameron, S.A, Firestone, R.S, Schramm, V.L, Almo, S.C.
Deposit date:2016-09-14
Release date:2017-10-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:TBA
To be published
4XCV
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BU of 4xcv by Molmil
Probable 2-hydroxyacid dehydrogenase from Rhizobium etli CFN 42 in complex with NADPH
Descriptor: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, NADP-dependent 2-hydroxyacid dehydrogenase, ...
Authors:Langner, K.M, Shabalin, I.G, Handing, K.B, Gasiorowska, O.A, Stead, M, Hillerich, B.S, Chowdhury, S, Hammonds, J, Zimmerman, M.D, Al Obadi, N, Bonanno, J, Seidel, R, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC)
Deposit date:2014-12-18
Release date:2014-12-31
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal structure of 2-hydroxyacid dehydrogenase from Rhizobium etli CFN 42 in complex with NADPH
to be published
4XK4
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BU of 4xk4 by Molmil
E. coli transcriptional regulator RUTR with dihydrouracil
Descriptor: DIHYDROPYRIMIDINE-2,4(1H,3H)-DIONE, HTH-type transcriptional regulator RutR
Authors:Shumilin, I.A, Cooper, D.R, Shabalin, I.G, Grabowski, M, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC)
Deposit date:2015-01-09
Release date:2015-05-13
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:E. COLI TRANSCRIPTIONAL REGULATOR RUTR WITH DIHYDROURACIL
to be published
8SWS
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BU of 8sws by Molmil
Structure of K. lactis PNP S42E-H98R variant bound to transition state analog DADMe-IMMUCILLIN G and sulfate
Descriptor: 2-amino-7-{[(3R,4R)-3-hydroxy-4-(hydroxymethyl)pyrrolidin-1-yl]methyl}-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one, Purine nucleoside phosphorylase, SULFATE ION
Authors:Fedorov, E, Ghosh, A.
Deposit date:2023-05-19
Release date:2023-10-18
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Phosphate Binding in PNP Alters Transition-State Analogue Affinity and Subunit Cooperativity.
Biochemistry, 62, 2023
8SWR
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BU of 8swr by Molmil
Structure of K. lactis PNP S42E variant bound to transition state analog DADMe-IMMUCILLIN G and sulfate
Descriptor: 2-amino-7-{[(3R,4R)-3-hydroxy-4-(hydroxymethyl)pyrrolidin-1-yl]methyl}-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one, GUANINE, Purine nucleoside phosphorylase, ...
Authors:Fedorov, E, Ghosh, A.
Deposit date:2023-05-19
Release date:2023-10-18
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Phosphate Binding in PNP Alters Transition-State Analogue Affinity and Subunit Cooperativity.
Biochemistry, 62, 2023

225158

數據於2024-09-18公開中

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