6K4D
 
 | | Ancestral luciferase AncLamp in complex with ATP and D-luciferin | | Descriptor: | (4S)-2-(6-hydroxy-1,3-benzothiazol-2-yl)-4,5-dihydro-1,3-thiazole-4-carboxylic acid, Ancestral luciferase AncLamp, [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] (4S)-2-(6-oxidanyl-1,3-benzothiazol-2-yl)-4,5-dihydro-1,3-thiazole-4-carboxylate | | Authors: | Oba, Y, Konishi, K, Yano, D, Kato, D, Shirai, T. | | Deposit date: | 2019-05-23 | | Release date: | 2020-05-27 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Resurrecting the ancient glow of the fireflies.
Sci Adv, 6, 2020
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6K4C
 | | Ancestral luciferase AncLamp in complex with DLSA | | Descriptor: | 5'-O-[N-(DEHYDROLUCIFERYL)-SULFAMOYL] ADENOSINE, Ancestral luciferase AncLamp, MAGNESIUM ION | | Authors: | Oba, Y, Konishi, K, Yano, D, Kato, D, Shirai, T. | | Deposit date: | 2019-05-23 | | Release date: | 2020-05-27 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Resurrecting the ancient glow of the fireflies.
Sci Adv, 6, 2020
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6KOG
 | | Ketosynthase domain in tenuazonic acid synthetase 1 (TAS1). | | Descriptor: | GLYCEROL, Hybrid PKS-NRPS synthetase TAS1, SULFATE ION | | Authors: | Yun, C.S, Nishimoto, K, Motoyama, T, Hino, T, Nagano, S, Osada, H. | | Deposit date: | 2019-08-10 | | Release date: | 2020-07-01 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.68 Å) | | Cite: | Unique features of the ketosynthase domain in a nonribosomal peptide synthetase-polyketide synthase hybrid enzyme, tenuazonic acid synthetase 1.
J.Biol.Chem., 295, 2020
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6KO7
 | | Crystal structure of the Ethidium bound RamR determined with XtaLAB Synergy | | Descriptor: | ETHIDIUM, Putative regulatory protein, SULFATE ION | | Authors: | Matsumoto, T, Nakashima, R, Yamano, A, Nishino, K. | | Deposit date: | 2019-08-08 | | Release date: | 2019-10-09 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Development of a structure determination method using a multidrug-resistance regulator protein as a framework.
Biochem.Biophys.Res.Commun., 518, 2019
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6KO9
 | | Crystal structure of the Gefitinib Intermediate 1 bound RamR determined with XtaLAB Synergy | | Descriptor: | 4-[(3-chloranyl-4-fluoranyl-phenyl)amino]-7-methoxy-quinazolin-6-ol, Putative regulatory protein, SULFATE ION | | Authors: | Matsumoto, T, Nakashima, R, Yamano, A, Nishino, K. | | Deposit date: | 2019-08-08 | | Release date: | 2019-10-09 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Development of a structure determination method using a multidrug-resistance regulator protein as a framework.
Biochem.Biophys.Res.Commun., 518, 2019
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6KO8
 | | Crystal structure of the Cholic acid bound RamR determined with XtaLAB Synergy | | Descriptor: | CHOLIC ACID, Putative regulatory protein, SULFATE ION | | Authors: | Matsumoto, T, Nakashima, R, Yamano, A, Nishino, K. | | Deposit date: | 2019-08-08 | | Release date: | 2019-10-09 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Development of a structure determination method using a multidrug-resistance regulator protein as a framework.
Biochem.Biophys.Res.Commun., 518, 2019
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2ZZ9
 | | Structure of aquaporin-4 S180D mutant at 2.8 A resolution by electron crystallography | | Descriptor: | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, Aquaporin-4 | | Authors: | Tani, K, Mitsuma, T, Hiroaki, Y, Kamegawa, A, Nishikawa, K, Tanimura, Y, Fujiyoshi, Y. | | Deposit date: | 2009-02-06 | | Release date: | 2009-06-09 | | Last modified: | 2023-11-08 | | Method: | ELECTRON CRYSTALLOGRAPHY (2.8 Å) | | Cite: | Mechanism of Aquaporin-4's Fast and Highly Selective Water Conduction and Proton Exclusion.
J.Mol.Biol., 389, 2009
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2Z9U
 | | Crystal structure of pyridoxamine-pyruvate aminotransferase from Mesorhizobium loti at 2.0 A resolution | | Descriptor: | Aspartate aminotransferase, GLYCEROL, SULFATE ION | | Authors: | Yoshikane, Y, Yokochi, N, Yamasaki, M, Mizutani, K, Ohnishi, K, Mikami, B, Hayashi, H, Yagi, T. | | Deposit date: | 2007-09-26 | | Release date: | 2007-11-06 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure of pyridoxamine-pyruvate aminotransferase from Mesorhizobium loti MAFF303099
J.Biol.Chem., 283, 2008
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2Z1I
 | | Crystal structure of E.coli RNase HI surface charged mutant(Q4R/T40E/Q72H/Q76K/Q80E/T92K/Q105K/Q113R/Q115K) | | Descriptor: | Ribonuclease HI | | Authors: | You, D.J, Fukuchi, S, Nishikawa, K, Koga, Y, Takano, K, Kanaya, S. | | Deposit date: | 2007-05-08 | | Release date: | 2007-11-13 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Protein Thermostabilization Requires a Fine-tuned Placement of Surface-charged Residues
J.Biochem.(Tokyo), 142, 2007
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2Z1J
 | | Crystal structure of E.coli RNase HI surface charged mutant(Q4R/T40E/Q72H/Q76K/Q80E/T92K/Q105K/Q113R/Q115K/N143K/T145K) | | Descriptor: | Ribonuclease HI | | Authors: | You, D.J, Fukuchi, S, Nishikawa, K, Koga, Y, Takano, K, Kanaya, S. | | Deposit date: | 2007-05-08 | | Release date: | 2007-11-13 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.38 Å) | | Cite: | Protein Thermostabilization Requires a Fine-tuned Placement of Surface-charged Residues
J.Biochem.(Tokyo), 142, 2007
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2Z9V
 | | Crystal structure of pyridoxamine-pyruvate aminotransferase complexed with pyridoxamine | | Descriptor: | 4-(AMINOMETHYL)-5-(HYDROXYMETHYL)-2-METHYLPYRIDIN-3-OL, Aspartate aminotransferase, GLYCEROL, ... | | Authors: | Yoshikane, Y, Yokochi, N, Yamasaki, M, Mizutani, K, Ohnishi, K, Mikami, B, Hayashi, H, Yagi, T. | | Deposit date: | 2007-09-26 | | Release date: | 2007-11-06 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Crystal structure of pyridoxamine-pyruvate aminotransferase from Mesorhizobium loti MAFF303099
J.Biol.Chem., 283, 2008
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2Z9X
 | | Crystal structure of pyridoxamine-pyruvate aminotransferase complexed with pyridoxyl-L-alanine | | Descriptor: | 3-HYDROXY-5-(HYDROXYMETHYL)-2-METHYLISONICOTINALDEHYDE, ALANINE, Aspartate aminotransferase, ... | | Authors: | Yoshikane, Y, Yokochi, N, Yamasaki, M, Mizutani, K, Ohnishi, K, Mikami, B, Hayashi, H, Yagi, T. | | Deposit date: | 2007-09-26 | | Release date: | 2007-11-06 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.94 Å) | | Cite: | Crystal structure of pyridoxamine-pyruvate aminotransferase from Mesorhizobium loti MAFF303099
J.Biol.Chem., 283, 2008
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3T37
 | | Crystal structure of pyridoxine 4-oxidase from Mesorbium loti | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Probable dehydrogenase | | Authors: | Mugo, A.N, Kobayashi, J, Mikami, B, Ohnishi, K, Yagi, T. | | Deposit date: | 2011-07-25 | | Release date: | 2012-08-15 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.193 Å) | | Cite: | Structure biology and crystallization communication
TO BE PUBLISHED
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2D57
 | | Double layered 2D crystal structure of AQUAPORIN-4 (AQP4M23) at 3.2 a resolution by electron crystallography | | Descriptor: | Aquaporin-4 | | Authors: | Hiroaki, Y, Tani, K, Kamegawa, A, Gyobu, N, Nishikawa, K, Suzuki, H, Walz, T, Sasaki, S, Mitsuoka, K, Kimura, K, Mizoguchi, A, Fujiyoshi, Y. | | Deposit date: | 2005-10-29 | | Release date: | 2006-01-31 | | Last modified: | 2023-11-08 | | Method: | ELECTRON CRYSTALLOGRAPHY (3.2 Å) | | Cite: | Implications of the Aquaporin-4 Structure on Array Formation and Cell Adhesion
J.Mol.Biol., 355, 2005
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7BU4
 | | Crystal structure of CK2a1 complexed with KY49 | | Descriptor: | 4-(6-aminocarbonyl-8-oxidanylidene-9-phenyl-7H-purin-2-yl)benzoic acid, Casein Kinase 2 subunit alpha | | Authors: | Tsuyuguchi, M, Kinoshita, T. | | Deposit date: | 2020-04-04 | | Release date: | 2021-04-07 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.70227313 Å) | | Cite: | Design, synthesis and SAR studies of protein kinase CK2 inhibitors with a purine scaffold
To Be Published
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3BM1
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7VR9
 | | Crystal structure of human serum albumin complex with aripiprazole and myristic acid | | Descriptor: | 7-[4-[4-[2,3-bis(chloranyl)phenyl]piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one, MYRISTIC ACID, Serum albumin | | Authors: | Kawai, A, Yamasaki, K, Otagiri, M. | | Deposit date: | 2021-10-22 | | Release date: | 2022-02-16 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Effects of Myristate on the Induced Circular Dichroism Spectra of Aripiprazole Bound to Human Serum Albumin: A Structural-Chemical Investigation
Acs Omega, 7, 2022
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7WKZ
 | | Crystal structure of the HSA complex with mycophenolate and aripiprazole | | Descriptor: | 7-[4-[4-[2,3-bis(chloranyl)phenyl]piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one, MYCOPHENOLIC ACID, Serum albumin | | Authors: | Kawai, A, Yamasaki, K. | | Deposit date: | 2022-01-12 | | Release date: | 2022-12-28 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.992 Å) | | Cite: | Structural Basis of the Change in the Interaction Between Mycophenolic Acid and Subdomain IIA of Human Serum Albumin During Renal Failure.
J.Med.Chem., 66, 2023
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7D6J
 | | Human serum albumin complexed with benzbromarone | | Descriptor: | Serum albumin, [3,5-bis(bromanyl)-4-oxidanyl-phenyl]-(2-ethyl-1-benzofuran-3-yl)methanone | | Authors: | Kawai, A, Yamasaki, K. | | Deposit date: | 2020-09-30 | | Release date: | 2021-02-03 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.29 Å) | | Cite: | Interaction of Benzbromarone with Subdomains IIIA and IB/IIA on Human Serum Albumin as the Primary and Secondary Binding Regions.
Mol Pharm., 18, 2021
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7X7X
 | | Human serum albumin complex with deschloro-aripiprazole | | Descriptor: | 7-[4-(4-phenylpiperazin-1-yl)butoxy]-3,4-dihydro-1H-quinolin-2-one, PHOSPHATE ION, Serum albumin | | Authors: | Kawai, A, Otagiri, M. | | Deposit date: | 2022-03-10 | | Release date: | 2022-09-07 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Chlorine Atoms of an Aripiprazole Molecule Control the Geometry and Motion of Aripiprazole and Deschloro-aripiprazole in Subdomain IIIA of Human Serum Albumin.
Acs Omega, 7, 2022
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3H1T
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6L48
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6L47
 | | Structure of the human sterol O-acyltransferase 1 in complex with CI-976 | | Descriptor: | 2,2-dimethyl-N-(2,4,6-trimethoxyphenyl)dodecanamide, CHOLESTEROL, Sterol O-acyltransferase 1 | | Authors: | Chen, L, Guan, C, Niu, Y. | | Deposit date: | 2019-10-16 | | Release date: | 2020-04-29 | | Last modified: | 2020-10-07 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Structural insights into the inhibition mechanism of human sterol O-acyltransferase 1 by a competitive inhibitor.
Nat Commun, 11, 2020
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3BF7
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3BF8
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