3PPN
 
 | | Structures of the substrate-binding protein provide insights into the multiple compatible solutes binding specificities of Bacillus subtilis ABC transporter OpuC | | Descriptor: | Glycine betaine/carnitine/choline-binding protein | | Authors: | Du, Y, Shi, W.W, He, Y.X, Yang, Y.H, Zhou, C.Z, Chen, Y. | | Deposit date: | 2010-11-24 | | Release date: | 2011-05-11 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structures of the substrate-binding protein provide insights into the multiple compatible solute binding specificities of the Bacillus subtilis ABC transporter OpuC
Biochem.J., 436, 2011
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3QUW
 | | Crystal structure of yeast Mmf1 | | Descriptor: | Protein MMF1 | | Authors: | Jiang, Y.L, Pu, Y.G, Ma, X.X, Chen, Y, Zhou, C.Z. | | Deposit date: | 2011-02-24 | | Release date: | 2011-06-08 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Crystal structures and putative interface of Saccharomyces cerevisiae mitochondrial matrix proteins Mmf1 and Mam33.
J.Struct.Biol., 175, 2011
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3QWB
 | | Crystal structure of Saccharomyces cerevisiae Zeta-crystallin-like quinone oxidoreductase Zta1 complexed with NADPH | | Descriptor: | GLYCEROL, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Probable quinone oxidoreductase | | Authors: | Guo, P.C, Ma, X.X, Bao, Z.Z, Chen, Y.X, Zhou, C.Z. | | Deposit date: | 2011-02-28 | | Release date: | 2012-02-08 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.59 Å) | | Cite: | Structural insights into the cofactor-assisted substrate recognition of yeast quinone oxidoreductase Zta1
J.Struct.Biol., 176, 2011
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3QPM
 | | Crystal structure of peroxiredoxin Prx4 from Pseudosciaena crocea | | Descriptor: | GLYCEROL, Peroxiredoxin | | Authors: | Lian, F.M, Teng, Y.B, Jiang, Y.L, He, Y.X, Chen, Y, Zhou, C.Z. | | Deposit date: | 2011-02-14 | | Release date: | 2012-02-22 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | The N-terminal beta-sheet of peroxiredoxin Prx4 in the large yellow croaker Pseudosciaena crocea is critical for its peroxidase and anti-bacterial activities
To be Published
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3QFO
 | | Crystal structure of Streptococcal asymmetric Ap4A hydrolase and phosphodiesterase Spr1479/SapH im complex with AMP | | Descriptor: | ADENOSINE MONOPHOSPHATE, FE (III) ION, MANGANESE (II) ION, ... | | Authors: | Jiang, Y.L, Zhang, J.W, Yu, W.L, Cheng, W, Zhang, C.C, Zhou, C.Z, Chen, Y. | | Deposit date: | 2011-01-22 | | Release date: | 2011-08-24 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural and enzymatic characterization of a Streptococcal ATP/diadenosine polyphosphate and phosphodiester hydrolase Spr1479/SapH
To be Published
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3QFN
 | | Crystal structure of Streptococcal asymmetric Ap4A hydrolase and phosphodiesterase Spr1479/SapH in complex with inorganic phosphate | | Descriptor: | FE (III) ION, MANGANESE (II) ION, PHOSPHATE ION, ... | | Authors: | Jiang, Y.L, Zhang, J.W, Yu, W.L, Cheng, W, Zhang, C.C, Zhou, C.Z, Chen, Y. | | Deposit date: | 2011-01-22 | | Release date: | 2011-08-24 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.31 Å) | | Cite: | Structural and enzymatic characterization of a Streptococcal ATP/diadenosine polyphosphate and phosphodiester hydrolase Spr1479/SapH
To be Published
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4NT9
 | | Crystal structure of an L,D-carboxypeptidase DacB from Streptococcus pneumonia | | Descriptor: | ACETATE ION, GLYCEROL, Putative uncharacterized protein, ... | | Authors: | Yang, Y.H, Zhang, J, Jiang, Y.L, Zhou, C.Z, Chen, Y. | | Deposit date: | 2013-12-02 | | Release date: | 2014-11-12 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.705 Å) | | Cite: | Crystal structure of an L,D-carboxypeptidase DacB from Streptococcus pneumonia
To be Published
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4OI3
 | | Crystal structure analysis of SCO4226 from Streptomyces coelicolor A3(2) | | Descriptor: | Nickel responsive protein | | Authors: | Lu, M, Jiang, Y.L, Wang, S, Cheng, W, Zhang, R.G, Virolle, M.J, Chen, Y, Zhou, C.Z. | | Deposit date: | 2014-01-18 | | Release date: | 2014-09-17 | | Last modified: | 2014-10-22 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Streptomyces coelicolor SCO4226 Is a Nickel Binding Protein.
Plos One, 9, 2014
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4OI6
 | | Crystal structure analysis of nickel-bound form SCO4226 from Streptomyces coelicolor A3(2) | | Descriptor: | CITRIC ACID, NICKEL (II) ION, Nickel responsive protein | | Authors: | Lu, M, Jiang, Y.L, Wang, S, Cheng, W, Zhang, R.G, Virolle, M.J, Chen, Y, Zhou, C.Z. | | Deposit date: | 2014-01-18 | | Release date: | 2014-09-10 | | Last modified: | 2018-01-24 | | Method: | X-RAY DIFFRACTION (2.04 Å) | | Cite: | Streptomyces coelicolor SCO4226 Is a Nickel Binding Protein.
Plos One, 9, 2014
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4R7B
 | | Crystal structure of pneumococcal LicA in complex with choline | | Descriptor: | CHOLINE ION, Choline kinase | | Authors: | Wang, L, Jiang, Y.L, Zhou, C.Z, Chen, Y.X. | | Deposit date: | 2014-08-27 | | Release date: | 2015-08-12 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.01 Å) | | Cite: | Structural and enzymatic characterization of the choline kinase LicA from Streptococcus pneumoniae
Plos One, 10, 2015
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4PQG
 | | Crystal structure of the pneumococcal O-GlcNAc transferase GtfA in complex with UDP and GlcNAc | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Glycosyltransferase Gtf1, URIDINE-5'-DIPHOSPHATE | | Authors: | Shi, W.W, Jiang, Y.L, Zhu, F, Yang, Y.H, Wu, H, Ren, Y.M, Chen, Y, Zhou, C.Z. | | Deposit date: | 2014-03-03 | | Release date: | 2014-06-18 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure of a Novel O-Linked N-Acetyl-d-glucosamine (O-GlcNAc) Transferase, GtfA, Reveals Insights into the Glycosylation of Pneumococcal Serine-rich Repeat Adhesins.
J.Biol.Chem., 289, 2014
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4Q2W
 | | Crystal Structure of pneumococcal peptidoglycan hydrolase LytB | | Descriptor: | GLYCEROL, Putative endo-beta-N-acetylglucosaminidase | | Authors: | Bai, X.H, Chen, H.J, Jiang, Y.L, Wen, Z, Cheng, W, Li, Q, Zhang, J.R, Chen, Y, Zhou, C.Z. | | Deposit date: | 2014-04-10 | | Release date: | 2014-07-16 | | Last modified: | 2019-12-18 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Structure of pneumococcal peptidoglycan hydrolase LytB reveals insights into the bacterial cell wall remodeling and pathogenesis.
J.Biol.Chem., 289, 2014
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4R78
 | | Crystal structure of LicA in complex with AMP | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ADENOSINE MONOPHOSPHATE, Choline kinase | | Authors: | Wang, L, Jiang, Y.L, Zhou, C.Z, Chen, Y.X. | | Deposit date: | 2014-08-27 | | Release date: | 2015-08-12 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Structural and enzymatic characterization of the choline kinase LicA from Streptococcus pneumoniae
Plos One, 10, 2015
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4R77
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8JY5
 | | Cryo-EM structure of human ABC transporter ABCC2 in apo" state | | Descriptor: | ATP-binding cassette sub-family C member 2 | | Authors: | Mao, Y.X, Chen, Z.P, Wang, L, Hou, W.T, Chen, Y.X, Zhou, C.Z. | | Deposit date: | 2023-07-03 | | Release date: | 2024-01-03 | | Last modified: | 2024-02-28 | | Method: | ELECTRON MICROSCOPY (4.17 Å) | | Cite: | Transport mechanism of human bilirubin transporter ABCC2 tuned by the inter-module regulatory domain.
Nat Commun, 15, 2024
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8JY4
 | | Cryo-EM structure of human ABC transporter ABCC2 in apo' state | | Descriptor: | ATP-binding cassette sub-family C member 2 | | Authors: | Mao, Y.X, Chen, Z.P, Wang, L, Hou, W.T, Chen, Y.X, Zhou, C.Z. | | Deposit date: | 2023-07-02 | | Release date: | 2024-01-03 | | Last modified: | 2024-02-28 | | Method: | ELECTRON MICROSCOPY (3.58 Å) | | Cite: | Transport mechanism of human bilirubin transporter ABCC2 tuned by the inter-module regulatory domain.
Nat Commun, 15, 2024
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8JX7
 | | Cryo-EM structure of human ABC transporter ABCC2 | | Descriptor: | ATP-binding cassette sub-family C member 2 | | Authors: | Mao, Y.X, Chen, Z.P, Wang, L, Hou, W.T, Chen, Y.X, Zhou, C.Z. | | Deposit date: | 2023-06-30 | | Release date: | 2024-01-03 | | Last modified: | 2024-02-28 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Transport mechanism of human bilirubin transporter ABCC2 tuned by the inter-module regulatory domain.
Nat Commun, 15, 2024
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8JXU
 | | Cryo-EM structure of human ABC transporter ABCC2 under active turnover condition | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 2, ... | | Authors: | Mao, Y.X, Chen, Z.P, Wang, L, Hou, W.T, Chen, Y.X, Zhou, C.Z. | | Deposit date: | 2023-07-01 | | Release date: | 2024-01-03 | | Last modified: | 2024-02-28 | | Method: | ELECTRON MICROSCOPY (3.55 Å) | | Cite: | Transport mechanism of human bilirubin transporter ABCC2 tuned by the inter-module regulatory domain.
Nat Commun, 15, 2024
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8J3W
 | | Cryo-EM structure of aspirin-bound ABCC4 | | Descriptor: | 2-(ACETYLOXY)BENZOIC ACID, ATP-binding cassette sub-family C member 4 | | Authors: | Chen, Y, Wang, L, Hou, W.T, Zhou, C.Z, Chen, Y, Li, Q. | | Deposit date: | 2023-04-18 | | Release date: | 2023-05-24 | | Method: | ELECTRON MICROSCOPY (3.07 Å) | | Cite: | Cryo-EM structure ofABCC4
Nat Cardiovasc Res, 2023
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8J3Z
 | | Cryo-EM structure of ATP-U46619-bound ABCC4 | | Descriptor: | (5Z)-7-{(1R,4S,5S,6R)-6-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-2-oxabicyclo[2.2.1]hept-5-yl}hept-5-enoic acid, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 4, ... | | Authors: | Chen, Y, Wang, L, Hou, W.T, Zhou, C.Z, Chen, Y, Li, Q. | | Deposit date: | 2023-04-18 | | Release date: | 2023-05-24 | | Method: | ELECTRON MICROSCOPY (3.17 Å) | | Cite: | Cryo-EM structure ofABCC4
Nat Cardiovasc Res, 2023
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8JUL
 | | Cryo-EM structure of SIDT1 in complex with phosphatidic acid | | Descriptor: | 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, SID1 transmembrane family member 1, ZINC ION | | Authors: | Sun, C.R, Xu, D, Li, Q, Zhou, C.Z, Chen, Y. | | Deposit date: | 2023-06-26 | | Release date: | 2023-11-15 | | Last modified: | 2024-01-24 | | Method: | ELECTRON MICROSCOPY (2.92 Å) | | Cite: | Human SIDT1 mediates dsRNA uptake via its phospholipase activity.
Cell Res., 34, 2024
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8JUN
 | | Cryo-EM structure of SIDT1 E555Q mutant | | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SID1 transmembrane family member 1, ZINC ION | | Authors: | Sun, C.R, Xu, D, Li, Q, Zhou, C.Z, Chen, Y. | | Deposit date: | 2023-06-26 | | Release date: | 2023-11-15 | | Last modified: | 2024-01-24 | | Method: | ELECTRON MICROSCOPY (2.38 Å) | | Cite: | Human SIDT1 mediates dsRNA uptake via its phospholipase activity.
Cell Res., 34, 2024
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8JXQ
 | | Cryo-EM structure of bilirubin ditaurate (BDT) bound human ABC transporter ABCC2 | | Descriptor: | 2-[3-[5-[(E)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-2-[[5-[(3-ethenyl-4-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-3-[3-oxidanylidene-3-(2-sulfoethylamino)propyl]-1H-pyrrol-2-yl]methyl]-4-methyl-1H-pyrrol-3-yl]propanoylamino]ethanesulfonic acid, ATP-binding cassette sub-family C member 2, CHOLESTEROL | | Authors: | Mao, Y.X, Chen, Z.P, Wang, L, Hou, W.T, Chen, Y.X, Zhou, C.Z. | | Deposit date: | 2023-07-01 | | Release date: | 2024-01-03 | | Last modified: | 2024-02-28 | | Method: | ELECTRON MICROSCOPY (3.32 Å) | | Cite: | Transport mechanism of human bilirubin transporter ABCC2 tuned by the inter-module regulatory domain.
Nat Commun, 15, 2024
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7XSD
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7VGJ
 | | Cryo-EM structure of the human P4-type flippase ATP8B1-CDC50A in the auto-inhibited E2Pi-PS state | | Descriptor: | Cell cycle control protein 50A, O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine, Phospholipid-transporting ATPase IC | | Authors: | Chen, M.T, Chen, Y, Chen, Z.P, Zhou, C.Z, Hou, W.T, Chen, Y. | | Deposit date: | 2021-09-16 | | Release date: | 2022-03-30 | | Last modified: | 2022-10-12 | | Method: | ELECTRON MICROSCOPY (3.98 Å) | | Cite: | Structural insights into the activation of autoinhibited human lipid flippase ATP8B1 upon substrate binding.
Proc.Natl.Acad.Sci.USA, 119, 2022
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